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person · Reporting owner

ESHELMAN FREDRIC N

Disclosed activity across 8 companies

Tapewire entity
122866
SEC CIK
0001033409

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Aravive, Inc.ARAV · Entity 114535Director · Executive Chairman · 10% ownerOctober 24, 2022October 26, 2022
G1 Therapeutics, Inc.GTHX · Entity 87413DirectorJune 11, 2020June 12, 2020
HYPERION DEFI, INC.EYEN · Entity 7220DirectorNovember 17, 2021November 22, 2021
Jasper Therapeutics, Inc.AMHCU · Entity 7588DirectorNovember 19, 2019November 19, 2019
Liquidia Technologies IncLQDA · Entity 14505110% ownerNovember 25, 2020November 27, 2020
MEDICINES CO /DEMDCO · Entity 152552Director · Executive ChairmanMay 31, 2018June 04, 2018

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Aravive, Inc.

Report date October 24, 2022 · Filed October 26, 2022

Jointly reported with Eshelman Ventures, LLC

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectSee footnote25,517,889 Reported balance After 2022-10-24 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 1 · 2022-10-24 · Grant · Acquired 16,306,120 · Balance 25,517,889

F1: On October 24, 2022, Aravive, Inc. (the "Company") agreed to issue approximately $41.5 million of securities including shares of its common stock and warrants (the "Warrants") to purchase shares of common stock in a private placement transaction (the "Private Placement") to certain investors, including Eshelman Ventures, LLC. The combined purchase price of each share of common stock and accompanying Warrants is $0.9199.

F2: The shares of common stock and Warrants reported herein are owned directly by Eshelman Ventures, LLC, an entity wholly owned by the reporting person, Dr. Fredric N. Eshelman. Dr. Eshelman is the Executive Chairman of the Company's Board of Directors and disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

Series A Warrants (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.79IndirectSee footnote8,153,060 Reported balance After 2022-10-24 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2022-10-24 · Grant · Acquired 8,153,060 · Balance 8,153,060

F1: On October 24, 2022, Aravive, Inc. (the "Company") agreed to issue approximately $41.5 million of securities including shares of its common stock and warrants (the "Warrants") to purchase shares of common stock in a private placement transaction (the "Private Placement") to certain investors, including Eshelman Ventures, LLC. The combined purchase price of each share of common stock and accompanying Warrants is $0.9199.

F3: The Series A Warrants are exercisable at any time after the Authorized Share Increase (as defined below) and will expire on the date that is the later of (i) fifteen (15) months after the date of the Authorized Share Increase, or (ii) one (1) month after public announcement by or on behalf of the Company of the publication of top line data from the Company's Phase 3 trial of batiraxcept in platinum-resistant ovarian cancer.

F4: In connection with the Private Placement, the Company has agreed to convene a special meeting of its stockholders or to seek written consent of the stockholders no later than 120 days following the closing of the Private Placement to seek approval of an increase in the number of the Company's authorized shares of common stock pursuant to an amendment to the Company's Certificate of Incorporation (such increase, the "Authorized Share Increase") to allow for full sufficient authorized and unissued shares of common stock for the full exercise of all of the Warrants and the shares of common stock issuable upon exercise thereof.

F2: The shares of common stock and Warrants reported herein are owned directly by Eshelman Ventures, LLC, an entity wholly owned by the reporting person, Dr. Fredric N. Eshelman. Dr. Eshelman is the Executive Chairman of the Company's Board of Directors and disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

Series B Warrants (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.79IndirectSee Footnote8,153,060 Reported balance After 2022-10-24 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2022-10-24 · Grant · Acquired 8,153,060 · Balance 8,153,060

F1: On October 24, 2022, Aravive, Inc. (the "Company") agreed to issue approximately $41.5 million of securities including shares of its common stock and warrants (the "Warrants") to purchase shares of common stock in a private placement transaction (the "Private Placement") to certain investors, including Eshelman Ventures, LLC. The combined purchase price of each share of common stock and accompanying Warrants is $0.9199.

F5: The Series B Warrants are exercisable at any time after the Authorized Share Increase and will expire thirty (30) months after the Authorized Share Increase.

F2: The shares of common stock and Warrants reported herein are owned directly by Eshelman Ventures, LLC, an entity wholly owned by the reporting person, Dr. Fredric N. Eshelman. Dr. Eshelman is the Executive Chairman of the Company's Board of Directors and disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: On October 24, 2022, Aravive, Inc. (the "Company") agreed to issue approximately $41.5 million of securities including shares of its common stock and warrants (the "Warrants") to purchase shares of common stock in a private placement transaction (the "Private Placement") to certain investors, including Eshelman Ventures, LLC. The combined purchase price of each share of common stock and accompanying Warrants is $0.9199.

F2: The shares of common stock and Warrants reported herein are owned directly by Eshelman Ventures, LLC, an entity wholly owned by the reporting person, Dr. Fredric N. Eshelman. Dr. Eshelman is the Executive Chairman of the Company's Board of Directors and disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

F3: The Series A Warrants are exercisable at any time after the Authorized Share Increase (as defined below) and will expire on the date that is the later of (i) fifteen (15) months after the date of the Authorized Share Increase, or (ii) one (1) month after public announcement by or on behalf of the Company of the publication of top line data from the Company's Phase 3 trial of batiraxcept in platinum-resistant ovarian cancer.

F4: In connection with the Private Placement, the Company has agreed to convene a special meeting of its stockholders or to seek written consent of the stockholders no later than 120 days following the closing of the Private Placement to seek approval of an increase in the number of the Company's authorized shares of common stock pursuant to an amendment to the Company's Certificate of Incorporation (such increase, the "Authorized Share Increase") to allow for full sufficient authorized and unissued shares of common stock for the full exercise of all of the Warrants and the shares of common stock issuable upon exercise thereof.

F5: The Series B Warrants are exercisable at any time after the Authorized Share Increase and will expire thirty (30) months after the Authorized Share Increase.

G1 Therapeutics, Inc.

Report date June 11, 2020 · Filed June 12, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.59 · Expires 2030-06-11Direct20,000 Reported balance After 2020-06-11 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2020-06-11 · Grant · Acquired 20,000 · Balance 20,000

F1: The shares underlying this option will vest in their entirety twelve months after June 11, 2020, subject to the Reporting Person's continued service as a director.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option will vest in their entirety twelve months after June 11, 2020, subject to the Reporting Person's continued service as a director.

HYPERION DEFI, INC.

Report date November 17, 2021 · Filed November 22, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common Stock, par value $.0001SEC Table I · non-derivativeDirect1,299,750 Reported balance After 2021-11-17 transaction · row 1
1 source row

Row 1 · 2021-11-17 · Grant · Acquired 6,963 · Balance 1,299,750

F1: Represents restricted stock units that fully vest on the earlier of November 17, 2022 or the date of the Issuer's 2022 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.59 · Expires 2031-11-17Direct9,653 Reported balance After 2021-11-17 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2021-11-17 · Grant · Acquired 9,653 · Balance 9,653

F2: The option becomes exercisable on the earlier of November 17, 2022 or the date of the Issuer's 2022 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Filing footnotes · ownership attribution and instrument terms

F1: Represents restricted stock units that fully vest on the earlier of November 17, 2022 or the date of the Issuer's 2022 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

F2: The option becomes exercisable on the earlier of November 17, 2022 or the date of the Issuer's 2022 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Jasper Therapeutics, Inc.

Report date November 19, 2019 · Filed November 19, 2019

This filing explicitly reported no securities owned.

Liquidia Technologies Inc

Report date November 25, 2020 · Filed November 27, 2020

Jointly reported with Eshelman Ventures, LLC

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect6,570,569 Reported balance After 2020-11-25 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 1 · 2020-11-25 · Sale · Disposed 17,364 · Balance 6,570,569

F1: The securities reported as directly beneficially owned by the Reporting Person may be deemed to be indirectly beneficially owned by the Dr. Eshelman, who is the manager of the Reporting Person.

Common StockSEC Table I · non-derivativeIndirectBy Fred Eshelman, manager of Eshelman Ventures, LLC175,573 Reported balance Holding disclosure · report date 2020-11-25 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 175,573

Filing footnotes · ownership attribution and instrument terms

F1: The securities reported as directly beneficially owned by the Reporting Person may be deemed to be indirectly beneficially owned by the Dr. Eshelman, who is the manager of the Reporting Person.

MEDICINES CO /DE

Report date May 31, 2018 · Filed June 04, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect1,132,149 Reported balance After 2018-05-31 transaction · row 1
1 source row

Row 1 · 2018-05-31 · Grant · Acquired 3,766 · Balance 1,132,149

F1: The restricted stock award vests on May 31, 2019 and was made as part of and pursuant to Issuer's director compensation program.

Stock Option (right-to-buy)SEC Table II · derivative / convertible security · Conversion / exercise price $33.86 · Expires 2028-05-31Direct14,141 Reported balance After 2018-05-31 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2018-05-31 · Grant · Acquired 14,141 · Balance 14,141

F3: The option vests in one installment on May 31, 2019 and was made as part of and pursuant to the Issuer's director compensation program.

Common StockSEC Table I · non-derivativeIndirectSee footnote944,537 Reported balance Holding disclosure · report date 2018-05-31 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 944,537

F2: These shares of the Issuer's common stock are owned by Eshelman Ventures, LLC, an entity wholly owned by the reporting person.

Filing footnotes · ownership attribution and instrument terms

F1: The restricted stock award vests on May 31, 2019 and was made as part of and pursuant to Issuer's director compensation program.

F2: These shares of the Issuer's common stock are owned by Eshelman Ventures, LLC, an entity wholly owned by the reporting person.

F3: The option vests in one installment on May 31, 2019 and was made as part of and pursuant to the Issuer's director compensation program.

Past disclosures · reporting ended (2)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Bausch Health Companies Inc.

Report date April 30, 2018 · Filed May 03, 2018

Section 16 reporting ended · disclosed 2018-05-03. Current position is not established by this disclosure.

No balance rows disclosed in this filing.

Liquidia Corp

Report date January 26, 2021 · Filed January 27, 2021

Jointly reported with Eshelman Ventures, LLC

Section 16 reporting ended · disclosed 2021-01-27. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect2,601,210 Reported balance After 2021-01-26 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 1 · 2021-01-26 · Sale · Disposed 1,762,162 · Balance 2,601,210

F1: This transaction was executed in multiple trades at prices ranging from $2.94 to $3.3650. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the trades were effected.

F2: The securities reported as directly beneficially owned by the Reporting Person may be deemed to be indirectly beneficially owned by Dr. Eshelman, who is the manager of the Reporting Person.

Common StockSEC Table I · non-derivativeIndirectBy Fred Eshelman, manager of Eshelman Ventures, LLC175,573 Reported balance Holding disclosure · report date 2021-01-26 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 175,573

Filing footnotes · ownership attribution and instrument terms

F1: This transaction was executed in multiple trades at prices ranging from $2.94 to $3.3650. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the trades were effected.

F2: The securities reported as directly beneficially owned by the Reporting Person may be deemed to be indirectly beneficially owned by Dr. Eshelman, who is the manager of the Reporting Person.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
April 01, 2020 Filed Apr 3, 2020 17:40 UTC Liquidia Technologies Inc LQDA · Entity 145051 PurchaseCommon Stock 45,000 $4.89 $220,122.00
Disclosure

SEC source: 0001578563-20-000011 · primary_doc.xml · nonDerivative · entry 1

Eshelman Ventures, LLC · CIK 0001706673 · 10% owner

ESHELMAN FREDRIC N · CIK 0001033409 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Fred Eshelman, manager of Eshelman Ventures, LLC

Disclosed balance after: 89,100

F1 · price: This transaction was executed in multiple trades at prices ranging from $4.64 to $4.98. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the trades were effected.

Read SEC document
March 31, 2020 Filed Apr 1, 2020 17:35 UTC Liquidia Technologies Inc LQDA · Entity 145051 PurchaseCommon Stock 30,000 $4.87 $146,112.00
Disclosure

SEC source: 0001578563-20-000007 · primary_doc.xml · nonDerivative · entry 2

Eshelman Ventures, LLC · CIK 0001706673 · 10% owner

ESHELMAN FREDRIC N · CIK 0001033409 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Fred Eshelman, manager of Eshelman Ventures, LLC

Disclosed balance after: 44,100

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.64 to $4.96. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the trades were effected.

Read SEC document
March 30, 2020 Filed Apr 1, 2020 17:35 UTC Liquidia Technologies Inc LQDA · Entity 145051 PurchaseCommon Stock 14,100 $4.76 $67,106.13
Disclosure

SEC source: 0001578563-20-000007 · primary_doc.xml · nonDerivative · entry 1

Eshelman Ventures, LLC · CIK 0001706673 · 10% owner

ESHELMAN FREDRIC N · CIK 0001033409 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Fred Eshelman, manager of Eshelman Ventures, LLC

Disclosed balance after: 14,100

F1 · price: This transaction was executed in multiple trades at prices ranging from $4.51 to $4.79. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the trades were effected.

Read SEC document
August 16, 2019 Filed Aug 20, 2019 17:22 UTC HYPERION DEFI, INC. EYEN · Entity 7220 GrantStock Option (right to buy) · Derivative 9,057 $0.00 Strike: $3.11 $0.00
Disclosure

SEC source: 0001638599-19-000798 · doc4_6260.xml · derivative · entry 3

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,057

Underlying: Common Stock · 9,057 shares

Expires 2029-08-16

F3 · derivative.exercise_date: The option becomes exercisable on the earlier of August 16, 2020 or the date of the Issuer's 2020 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Read SEC document
August 16, 2019 Filed Aug 20, 2019 17:22 UTC HYPERION DEFI, INC. EYEN · Entity 7220 GrantCommon Stock, par value $.0001 8,038 $0.00 $0.00
Disclosure

SEC source: 0001638599-19-000798 · doc4_6260.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,285,499

F1 · shares: Represents restricted stock units that vest on the earlier of August 16, 2020 or the date of the Issuer's 2020 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Read SEC document
June 12, 2019 Filed Jun 14, 2019 16:38 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 GrantStock Option (right to buy) · Derivative 20,000 $0.00 Strike: $18.47 $0.00
Disclosure

SEC source: 0001209191-19-037157 · doc4.xml · derivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2029-06-12

F1 · derivative.exercise_date: The shares underlying this option will vest in their entirety twelve months after June 12, 2019, subject to the Reporting Person's continued service as a director.

Read SEC document
July 24, 2018 Filed Jul 26, 2018 18:12 UTC HYPERION DEFI, INC. EYEN · Entity 7220 GrantStock Option (right to buy) · Derivative 4,465 $0.00 Strike: $6.20 $0.00
Disclosure

SEC source: 0001638599-18-000819 · doc4_5548.xml · derivative · entry 3

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,655

Underlying: Common Stock · 4,465 shares

Expires 2028-07-24

F3 · derivative.exercise_date: The option becomes exercisable on the earlier of July 24, 2019 or the date of the Issuer's 2019 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Read SEC document
July 24, 2018 Filed Jul 26, 2018 18:12 UTC HYPERION DEFI, INC. EYEN · Entity 7220 GrantCommon Stock, par value $.0001 4,033 $0.00 $0.00
Disclosure

SEC source: 0001638599-18-000819 · doc4_5548.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,277,461

F1 · shares: Represents restricted stock units that vest on the earlier of July 24, 2019 or the date of the Issuer's 2019 annual meeting of stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors and acceleration upon change in control.

Read SEC document
June 07, 2018 Filed Jun 11, 2018 12:04 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 GrantStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $38.39 $0.00
Disclosure

SEC source: 0001209191-18-036865 · doc4.xml · derivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-06-07

F1 · derivative.exercise_date: The shares underlying this option will vest in their entirety twelve months after June 7, 2018, subject to the Reporting Person's continued service as a director.

Read SEC document
May 31, 2018 Filed Jun 4, 2018 16:58 UTC MEDICINES CO /DE MDCO · Entity 152552 GrantStock Option (right-to-buy) · Derivative 14,141 $0.00 Strike: $33.86 $0.00
Disclosure

SEC source: 0001179110-18-007959 · edgar.xml · derivative · entry 3

ESHELMAN FREDRIC N · CIK 0001033409 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,141

Underlying: Common Stock · 14,141 shares

Expires 2028-05-31

F3 · derivative.exercise_date: The option vests in one installment on May 31, 2019 and was made as part of and pursuant to the Issuer's director compensation program.

Read SEC document
May 31, 2018 Filed Jun 4, 2018 16:58 UTC MEDICINES CO /DE MDCO · Entity 152552 GrantCommon Stock 3,766 $0.00 $0.00
Disclosure

SEC source: 0001179110-18-007959 · edgar.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,132,149

F1 · shares: The restricted stock award vests on May 31, 2019 and was made as part of and pursuant to Issuer's director compensation program.

Read SEC document
January 29, 2018 Filed Feb 6, 2018 10:00 UTC HYPERION DEFI, INC. EYEN · Entity 7220 PurchaseCommon Stock, par value $.0001 335,000 $10.00 $3,350,000.00
Disclosure

SEC source: 0001144204-18-005875 · tv484957_4.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,273,428

Read SEC document
December 08, 2017 Filed Dec 11, 2017 18:23 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 100,000 $26.65 $2,665,000.00
Disclosure

SEC source: 0001179110-17-015232 · edgar.xml · nonDerivative · entry 2

ESHELMAN FREDRIC N · CIK 0001033409 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,128,383

F2 · price: The reported price in Column 4 is a weighted average purchase price. These shares were purchased in multiple transactions at prices ranging from $26.40 to $26.81 per share. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

Read SEC document
December 07, 2017 Filed Dec 11, 2017 18:23 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 100,000 $26.46 $2,646,000.00
Disclosure

SEC source: 0001179110-17-015232 · edgar.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,028,383

F1 · price: The reported price in Column 4 is a weighted average purchase price. These shares were purchased in multiple transactions at prices ranging from $26.24 to $26.60 per share. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

Read SEC document
November 13, 2017 Filed Nov 15, 2017 17:12 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 PurchaseCommon Stock 250,000 $19.73 $4,932,500.00
Disclosure

SEC source: 0001578563-17-000011 · primary_doc.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 250,000

Read SEC document
July 11, 2017 Filed Jul 13, 2017 19:41 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 GrantStock Option (right to buy) · Derivative 20,000 $0.00 Strike: $15.55 $0.00
Disclosure

SEC source: 0001209191-17-045117 · doc4.xml · derivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2027-07-11

F1 · derivative.exercise_date: The stock option will vest in thirty-six monthly installments at the end of each successive month following July 11, 2017, subject to the Reporting Person's continued service as a director.

Read SEC document
May 25, 2017 Filed May 30, 2017 19:43 UTC MEDICINES CO /DE MDCO · Entity 152552 GrantStock Option (right-to-buy) · Derivative 13,577 $0.00 Strike: $39.39 $0.00
Disclosure

SEC source: 0001179110-17-008218 · edgar.xml · derivative · entry 3

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,577

Underlying: Common Stock · 13,577 shares

Expires 2027-05-25

F3 · derivative.exercise_date: This option vests in one installment on May 25, 2018 and is made as part of and pursuant to Issuer's director compensation package.

Read SEC document
May 25, 2017 Filed May 30, 2017 19:43 UTC MEDICINES CO /DE MDCO · Entity 152552 GrantCommon Stock 3,237 $0.00 $0.00
Disclosure

SEC source: 0001179110-17-008218 · edgar.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 928,383

F1 · shares: This restricted stock award vests on May 25, 2018 and is made as part of and pursuant to Issuer's director compensation package.

Read SEC document
May 22, 2017 Filed May 24, 2017 20:05 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 ConversionSeries C Preferred Stock · Derivative 2,524,233 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-17-035163 · doc4.xml · derivative · entry 4

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 841,411 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series B Preferred Stock and the Series C Preferred Stock converted to Common Stock on a 1-for-3 basis.

F1 · price: The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series B Preferred Stock and the Series C Preferred Stock converted to Common Stock on a 1-for-3 basis.

F4 · derivative.exercise_date: The Series B Preferred Stock and the Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date.

F4 · derivative.expiration_date: The Series B Preferred Stock and the Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date.

F2 · ownership.nature: Eshelman Ventures, LLC is the record holder of the securities. Dr. Fredric Eshelman is the founder and principal of Eshelman Ventures, LLC and may be deemed to beneficially own the securities held by Eshelman Ventures, LLC. Dr. Eshelman disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

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May 22, 2017 Filed May 24, 2017 20:05 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 ConversionSeries B Preferred Stock · Derivative 6,893,224 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-17-035163 · doc4.xml · derivative · entry 3

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 2,297,740 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series B Preferred Stock and the Series C Preferred Stock converted to Common Stock on a 1-for-3 basis.

F1 · price: The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series B Preferred Stock and the Series C Preferred Stock converted to Common Stock on a 1-for-3 basis.

F4 · derivative.exercise_date: The Series B Preferred Stock and the Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date.

F4 · derivative.expiration_date: The Series B Preferred Stock and the Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date.

F2 · ownership.nature: Eshelman Ventures, LLC is the record holder of the securities. Dr. Fredric Eshelman is the founder and principal of Eshelman Ventures, LLC and may be deemed to beneficially own the securities held by Eshelman Ventures, LLC. Dr. Eshelman disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

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May 22, 2017 Filed May 24, 2017 20:05 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 PurchaseCommon Stock 300,000 $15.00 $4,500,000.00
Disclosure

SEC source: 0001209191-17-035163 · doc4.xml · nonDerivative · entry 2

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 3,439,151

F3 · price: Reflects shares Eshelman Ventures, LLC purchased in the initial public offering at the initial public offering price of $15.00 per share.

F2 · ownership.nature: Eshelman Ventures, LLC is the record holder of the securities. Dr. Fredric Eshelman is the founder and principal of Eshelman Ventures, LLC and may be deemed to beneficially own the securities held by Eshelman Ventures, LLC. Dr. Eshelman disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

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May 22, 2017 Filed May 24, 2017 20:05 UTC G1 Therapeutics, Inc. GTHX · Entity 87413 ConversionCommon Stock 3,139,151 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-17-035163 · doc4.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 3,139,151

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series B Preferred Stock and the Series C Preferred Stock converted to Common Stock on a 1-for-3 basis.

F2 · ownership.nature: Eshelman Ventures, LLC is the record holder of the securities. Dr. Fredric Eshelman is the founder and principal of Eshelman Ventures, LLC and may be deemed to beneficially own the securities held by Eshelman Ventures, LLC. Dr. Eshelman disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

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May 05, 2017 Filed May 5, 2017 20:53 UTC Bausch Health Companies Inc. VRX · Entity 4363 GrantCommon Stock, no par value 25,406 $0.00 $0.00
Disclosure

SEC source: 0000885590-17-000025 · primary_doc.xml · nonDerivative · entry 2

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,298

F2 · shares: Regular annual Restricted Share Units (RSUs) equal to $250,000 granted to non-employee directors in office on the third trading day following the Annual Meeting of Shareholders based on the closing price of registrant common stock on the date prior to the grant. RSUs represent a contingent right to receive one share of common stock, no par value, of Valeant Pharmaceuticals International, Inc.

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May 03, 2017 Filed May 5, 2017 20:53 UTC Bausch Health Companies Inc. VRX · Entity 4363 Tax withholdingCommon Stock, no par value 4,904 $9.66 $47,372.64
Disclosure

SEC source: 0000885590-17-000025 · primary_doc.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,892

F1 · shares: This number represents common shares withheld to satisfy the tax withholding obligations due upon vesting of Restricted Share Units.

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December 08, 2016 Filed Dec 8, 2016 16:53 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 5,501 $33.19 $182,578.19
Disclosure

SEC source: 0001140361-16-089118 · doc1.xml · nonDerivative · entry 5

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 925,146

F5 · price: Represents the weighted average purchase price of the shares purchased ranging from a low of $33.07 to a high of $33.25 per share.

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December 08, 2016 Filed Dec 8, 2016 16:53 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 19,188 $32.51 $623,801.88
Disclosure

SEC source: 0001140361-16-089118 · doc1.xml · nonDerivative · entry 4

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 919,645

F4 · price: Represents the weighted average purchase price of the shares purchased ranging from a low of $32.07 to a high of $33.06 per share.

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December 07, 2016 Filed Dec 8, 2016 16:53 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 86,587 $32.90 $2,848,712.30
Disclosure

SEC source: 0001140361-16-089118 · doc1.xml · nonDerivative · entry 3

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 900,457

F3 · price: Represents the weighted average purchase price of the shares purchased ranging from a low of $32.29 to a high of $33.28 per share.

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December 07, 2016 Filed Dec 8, 2016 16:53 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 172,764 $33.61 $5,806,598.04
Disclosure

SEC source: 0001140361-16-089118 · doc1.xml · nonDerivative · entry 2

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 813,870

F2 · price: Represents the weighted average purchase price of the shares purchased ranging from a low of $33.29 to a high of $34.27 per share.

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December 06, 2016 Filed Dec 8, 2016 16:53 UTC MEDICINES CO /DE MDCO · Entity 152552 PurchaseCommon Stock 337,680 $34.15 $11,531,772.00
Disclosure

SEC source: 0001140361-16-089118 · doc1.xml · nonDerivative · entry 1

ESHELMAN FREDRIC N · CIK 0001033409 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 641,106

F1 · price: Represents the weighted average purchase price of the shares purchased ranging from a low of $33.83 to a high of $34.80 per share. The reporting person undertakes, upon request by the Commission staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price for these transactions and the other transactions reported on this Form 4 and described in notes 2 through 5.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.