Meister Keith A.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,539,356

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $144.50 to $145.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,592,132

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $143.50 to $144.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000351 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,738,297

F6 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $39.79 to $40.00.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,784,570 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000351 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,686,404

F5 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $38.79 to $39.77.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,784,570 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,604,441

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $148 to $148.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,609,751

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $147 to $147.98.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,616,275

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $145.75 to $146.74.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,669,885

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $144.75 to $145.73. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (5)-(13) to this Form 4.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000351 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,598,297

F4 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $39.21 to $39.80.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,784,570 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000351 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,527,371

F1 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $38.21 to $39.20. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the ranges set forth in footnotes (1), (4), (5), (6), (7) and (8) to this Form 4.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,784,570 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · derivative · entry 13

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 24,562

Underlying: Common Stock · 255,378 shares

Expires 2028-02-11

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F4 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 24,562 shares of common stock from the counterparty at $102.82 per share.

F3 · price: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,829,508

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F4 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 24,562 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,084,886

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F4 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 24,562 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · derivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 279,940

Underlying: Common Stock · 79,568 shares

Expires 2028-02-11

F4 · kind: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F4 · price: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,829,508

F4 · kind: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,909,076

F4 · kind: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 13

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,433,297

F15 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $40.22 to $40.41.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 12

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,432,765

F14 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $39.22 to $40.21.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 11

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,180,031

F13 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $38.22 to $39.21.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 10

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,933,297

F12 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $40.95 to $41.50.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 9

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,860,193

F11 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $39.95 to $40.94.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,781,049

F10 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $38.59 to $38.94.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,777,653

F9 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $37.59 to $38.58.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0000789570-26-000050 · form4.xml · derivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,298

Underlying: Common Stock $.01 Par Value ND · 6,298 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted Stock Units ("RSUs") granted under the MGM Resorts International ("Company") 2022 Omnibus Incentive Plan (the "Plan"). Each RSU represents the right to receive, following vesting, one share of Company common stock.

F4 · derivative.exercise_date: The RSUs will vest upon the earlier of (i) May 7, 2027 or (ii) the date of the Company's next annual meeting of stockholders, in each case subject to the terms of the Plan and applicable award agreement.

F4 · derivative.expiration_date: The RSUs will vest upon the earlier of (i) May 7, 2027 or (ii) the date of the Company's next annual meeting of stockholders, in each case subject to the terms of the Plan and applicable award agreement.

SEC source: 0001011438-26-000273 · form4.xml · derivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 359,508

Underlying: Common Stock · 9,236 shares

Expires 2028-02-11

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F3 · price: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,829,508

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,838,744

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,761,908

F8 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $40.05 to $40.66.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,705,278

F7 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $39.05 to $40.04.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,610,922

F6 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $38.05 to $39.04.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,494,510

F5 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $37.05 to $38.04.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,371,117

F4 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $35.97 to $36.84.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000276 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,356,331

F1 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $34.97 to $35.94. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the ranges set forth in footnotes (1), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), (14) and (15) to this Form 4.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 4,433,297 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0000789570-26-000050 · form4.xml · derivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,641.4963

Underlying: Common Stock $.01 Par Value ND · 6,675 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Represents Deferred Stock Units ("DSUs") under the MGM Resorts International (the "Company") Deferred Compensation Plan for Non-Employee Directors. Each DSU is the economic equivalent of one share of Company common stock. The DSUs become payable upon the Reporting Person's termination of service as a Director.

F3 · derivative.exercise_date: Represents Deferred Stock Units ("DSUs") under the MGM Resorts International (the "Company") Deferred Compensation Plan for Non-Employee Directors. Each DSU is the economic equivalent of one share of Company common stock. The DSUs become payable upon the Reporting Person's termination of service as a Director.

F3 · derivative.expiration_date: Represents Deferred Stock Units ("DSUs") under the MGM Resorts International (the "Company") Deferred Compensation Plan for Non-Employee Directors. Each DSU is the economic equivalent of one share of Company common stock. The DSUs become payable upon the Reporting Person's termination of service as a Director.

SEC source: 0000789570-26-000050 · form4.xml · derivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock $.01 Par Value ND · 6,675 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted Stock Units ("RSUs") granted under the MGM Resorts International ("Company") 2022 Omnibus Incentive Plan (the "Plan"). Each RSU represents the right to receive, following vesting, one share of Company common stock.

F2 · derivative.exercise_date: The RSUs vested on May 6, 2026, pursuant to the terms of the Plan and applicable award agreement.

F2 · derivative.expiration_date: The RSUs vested on May 6, 2026, pursuant to the terms of the Plan and applicable award agreement.

SEC source: 0000789570-26-000025 · form4.xml · derivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 62,966.4963

Underlying: Common Stock $.01 Par Value ND · 1,080.789 shares

Expires not disclosed

F1 · derivative.exercise_price: Represents Deferred Stock Units ("DSUs") under the MGM Resorts International (the "Company") Deferred Compensation Plan for Non-Employee Directors. Each DSU is the economic equivalent of one share of Company common stock. The DSUs become payable upon the Reporting Person's termination of service as a Director.

F1 · derivative.exercise_date: Represents Deferred Stock Units ("DSUs") under the MGM Resorts International (the "Company") Deferred Compensation Plan for Non-Employee Directors. Each DSU is the economic equivalent of one share of Company common stock. The DSUs become payable upon the Reporting Person's termination of service as a Director.

F1 · derivative.expiration_date: Represents Deferred Stock Units ("DSUs") under the MGM Resorts International (the "Company") Deferred Compensation Plan for Non-Employee Directors. Each DSU is the economic equivalent of one share of Company common stock. The DSUs become payable upon the Reporting Person's termination of service as a Director.

SEC source: 0001110803-26-000083 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,566

F1 · shares: Mr. Meister elected to receive 100% of his 2026 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Meister's 1st quarter 2026 retainer fees.

SEC source: 0001193125-26-098505 · ownership.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 5,347,978

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $34.25 to $34.35, inclusive. The Reporting Person undertakes to provide to MGM Resorts International (the "Issuer"), any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: These securities are held for the accounts of certain private investment funds for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP, Corvex Select Equity Master Fund LP and Corvex-E LP. The general partner of Corvex is controlled by the Reporting Person.

F3 · ownership.nature: For purposes of Section 16 of the Securities Exchange Act of 1934, the Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or any other purpose.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 10

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,228,150

F11 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $81.95 to $82.37.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 9

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,198,914

F10 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $80.95 to $81.94.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,138,022

F9 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $79.95 to $80.94.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,090,399

F8 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $78.75 to $79.00.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,088,428

F7 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $77.50 to $78.37.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,088,124

F6 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $75.97 to $76.00.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,087,875

F5 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $74.97 to $75.96.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,086,954

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,086,754

F4 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $71.00 to $71.97.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-094527 · ownership.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director · 10% owner

Corvex Management LP · CIK 0001535472 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,078,315

F1 · price: The price reported in Column 4 is a weighted average price. These shares were bought in multiple transactions within the range of $69.99 to $70.78. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the ranges set forth in footnotes (1), (4), (5), (6), (7), (8), (9), (10), and (11) to this Form 4.

F2 · ownership.nature: Investment funds advised by Corvex Management LP ("Corvex") are the direct holders of 3,228,150 shares of the Class A Common Stock, par value $0.0001 per share ("Class A Common Stock") of GeneDX Holdings Corp. (the "Issuer") reported herein. Mr. Meister may be deemed to indirectly beneficially own these shares by virtue of Mr. Meister's control of the general partner of Corvex.

F3 · ownership.nature: For the purposes of this filing, each of Corvex or Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001213900-26-018902 · marketforms-72257.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,443

F1 · shares: Represents restricted stock units, which vest on the earlier of: (1) the first anniversary of the grant date, or (2) the day prior to the Issuer's next annual general meeting of stockholders to occur after the grant date, subject to the Reporting Person's continued service on the Issuer's board of directors through such date.

F2 · balance_after: Includes an additional 0.006 shares due to rounding upon settlement of vested awards.

SEC source: 0001213900-26-001826 · marketforms-71690.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,189.994

F1 · shares: Represents restricted stock units received in lieu of cash retainer, which vest in four equal annual installments on April 2, 2026, July 2, 2026, October 2, 2026 and January 2, 2027.