ZLAB

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 14

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 930,650

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F15 · price: Reflects a weighted average sale price of $127.55 per share, at prices ranging from $126.94 to $127.94 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 13

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 950,094

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F14 · price: Reflects a weighted average sale price of $126.62 per share, at prices ranging from $125.93 to $126.92 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 12

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 952,117

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F13 · price: Reflects a weighted average sale price of $125.25 per share, at prices ranging from $124.92 to $125.71 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 11

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 952,977

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F12 · price: Reflects a weighted average sale price of $124.39 per share, at prices ranging from $123.89 to $124.81 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 10

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 956,591

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F11 · price: Reflects a weighted average sale price of $123.20 per share, at prices ranging from $122.79 to $123.60 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 9

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 957,869

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F10 · price: Reflects a weighted average sale price of $132.42 per share, at prices ranging from $132.41 to $133.23 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 8

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 958,458

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F9 · price: Reflects a weighted average sale price of $131.09 per share, at prices ranging from $131.09 to $131.76 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 7

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 958,950

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F8 · price: Reflects a weighted average sale price of $129.63 per share, at prices ranging from $129.20 to $130.04 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 6

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 960,767

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F7 · price: Reflects a weighted average sale price of $128.65 per share, at prices ranging from $128.19 to $129.19 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 5

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 963,467

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F6 · price: Reflects a weighted average sale price of $127.69 per share, at prices ranging from $127.16.10 to $128.16 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 4

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 967,977

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F5 · price: Reflects a weighted average sale price of $126.45 per share, at prices ranging from $126.12 to $127.12 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 3

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 976,667

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F4 · price: Reflects a weighted average sale price of $125.70 per share, at prices ranging from $125.11 to $126.11per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 2

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 997,161

F1 · kind: This transaction was automatically triggered pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person.

F3 · price: Reflects a weighted average sale price of $124.63 per share, at prices ranging from $124.10 to $125.10 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001567619-21-011576 · doc1.xml · derivative · entry 3

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,444,720

Underlying: Ordinary Shares · 111,112 shares

Expires 2025-10-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On April 7, 2021, the Reporting Person filed a Form 4 which inadvertently did not report that she exercised 111,112 Stock Options in connection with the sales of Ordinary Shares reported in such filing. However, as reported in this amendment, the Reporting Person exercised 111,112 Stock Options for Ordinary Shares, granted to her in connection with a stock option plan that fully vested on October 22, 2020. Accordingly, Table I, Column 5 is amended to reflect such acquisition of Ordinary Shares, pursuant to such exercise of Stock Options, giving effect to the various sale transactions previously reported on the initial filing of this Form 4.

F2 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 3, 2021, expires December 31, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1931.

F3 · derivative.exercise_date: The Stock Options fully vested as of October 22, 2020.

SEC source: 0001567619-21-011576 · doc1.xml · nonDerivative · entry 1

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,119,765

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On April 7, 2021, the Reporting Person filed a Form 4 which inadvertently did not report that she exercised 111,112 Stock Options in connection with the sales of Ordinary Shares reported in such filing. However, as reported in this amendment, the Reporting Person exercised 111,112 Stock Options for Ordinary Shares, granted to her in connection with a stock option plan that fully vested on October 22, 2020. Accordingly, Table I, Column 5 is amended to reflect such acquisition of Ordinary Shares, pursuant to such exercise of Stock Options, giving effect to the various sale transactions previously reported on the initial filing of this Form 4.

F2 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 3, 2021, expires December 31, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1931.

F1 · balance_after: On April 7, 2021, the Reporting Person filed a Form 4 which inadvertently did not report that she exercised 111,112 Stock Options in connection with the sales of Ordinary Shares reported in such filing. However, as reported in this amendment, the Reporting Person exercised 111,112 Stock Options for Ordinary Shares, granted to her in connection with a stock option plan that fully vested on October 22, 2020. Accordingly, Table I, Column 5 is amended to reflect such acquisition of Ordinary Shares, pursuant to such exercise of Stock Options, giving effect to the various sale transactions previously reported on the initial filing of this Form 4.

SEC source: 0000899243-21-014989 · doc4.xml · derivative · entry 2

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

Underlying: Ordinary Shares · 17,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one Ordinary Share of the issuer.

F3 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

F3 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

SEC source: 0000899243-21-014989 · doc4.xml · derivative · entry 1

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,000

Underlying: Ordinary Shares · 87,000 shares

Expires 2031-04-01

F1 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant.

SEC source: 0000899243-21-014994 · doc4.xml · derivative · entry 2

Liang Yi · CIK 0001835832 · CCO & President, Greater China

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,650

Underlying: Ordinary Shares · 3,650 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one Ordinary Share of the issuer.

F3 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

F3 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

SEC source: 0000899243-21-014994 · doc4.xml · derivative · entry 1

Liang Yi · CIK 0001835832 · CCO & President, Greater China

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Ordinary Shares · 20,000 shares

Expires 2031-04-01

F1 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant.

SEC source: 0000899243-21-014995 · doc4.xml · derivative · entry 2

Reinhart Harald · CIK 0001835824 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,050

Underlying: Ordinary Shares · 5,050 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one Ordinary Share of the issuer.

F3 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

F3 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

SEC source: 0000899243-21-014995 · doc4.xml · derivative · entry 1

Reinhart Harald · CIK 0001835824 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,650

Underlying: Ordinary Shares · 26,650 shares

Expires 2031-04-01

F1 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant.

SEC source: 0000899243-21-014992 · doc4.xml · derivative · entry 2

Edmondson Frazor Titus III · CIK 0001835780 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,150

Underlying: Ordinary Shares · 4,150 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one Ordinary Share of the issuer.

F3 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

F3 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

SEC source: 0000899243-21-014992 · doc4.xml · derivative · entry 1

Edmondson Frazor Titus III · CIK 0001835780 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,000

Underlying: Ordinary Shares · 22,000 shares

Expires 2031-04-01

F1 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant.

SEC source: 0000899243-21-014987 · doc4.xml · derivative · entry 2

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,300

Underlying: Ordinary Shares · 5,300 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one Ordinary Share of the issuer.

F3 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

F3 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

SEC source: 0000899243-21-014987 · doc4.xml · derivative · entry 1

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,000

Underlying: Ordinary Shares · 28,000 shares

Expires 2031-04-01

F1 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant.

SEC source: 0000899243-21-014986 · doc4.xml · derivative · entry 2

Cho William Ki Chul · CIK 0001835836 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,600

Underlying: Ordinary Shares · 4,600 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one Ordinary Share of the issuer.

F3 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

F3 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting.

SEC source: 0000899243-21-014986 · doc4.xml · derivative · entry 1

Cho William Ki Chul · CIK 0001835836 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,050

Underlying: Ordinary Shares · 24,050 shares

Expires 2031-04-01

F1 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant.

SEC source: 0000899243-21-015354 · doc4.xml · nonDerivative · entry 1

Du Ying · CIK 0001731790 · Director · Chairwoman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,008,653

F2 · price: On April 1, 2021, the Reporting Person made a charitable gift of 16,000 Ordinary Shares.

SEC source: 0000899243-21-013955 · doc4.xml · derivative · entry 3

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 480,000

Underlying: Ordinary Shares · 20,000 shares

Expires 2028-09-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person expiring on September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · derivative.exercise_date: The option vests in equal annual installments over five years beginning on 09/24/2019, the first anniversary of the date of grant.

SEC source: 0000899243-21-013955 · doc4.xml · nonDerivative · entry 1

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 207,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person expiring on September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000899243-21-014019 · doc4.xml · nonDerivative · entry 1

Chen Kai-Xian · CIK 0001836195 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,662

SEC source: 0000899243-22-006147 · doc5.xml · nonDerivative · entry 1

DIEKMAN JOHN D · CIK 0001240357 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,019

SEC source: 0000899243-21-002541 · doc4.xml · nonDerivative · entry 1

WIRTH PETER · CIK 0001021041 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 338,852

SEC source: 0000899243-21-002540 · doc4.xml · nonDerivative · entry 1

DIEKMAN JOHN D · CIK 0001240357 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,852

SEC source: 0000899243-21-002544 · doc4.xml · nonDerivative · entry 1

MOULDER LEON O JR · CIK 0001228865 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,852

SEC source: 0000899243-21-002543 · doc4.xml · nonDerivative · entry 1

Lis William · CIK 0001574558 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,277

SEC source: 0000899243-21-002539 · doc4.xml · nonDerivative · entry 1

Chen Kai-Xian · CIK 0001836195 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,964

SEC source: 0000899243-22-006141 · doc5.xml · nonDerivative · entry 1

Lis William · CIK 0001574558 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,927

F1 · kind: Disposition of shares to cover taxes. The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated December 4, 2020 and which expired January 5, 2021, and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.