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Nasdaq · USD

XENE

Xenon Pharmaceuticals Inc.

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2602
SEC CIK
0001582313
Parsed reports
275

Last 12 months

Inside the activity.

2 purchase rows · 26 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202501
Dec 202503
Jan 202602
Feb 202600
Mar 2026015
Apr 202600
May 202600
Jun 202602
Jul 202600
Aug 202603
Sep 202620
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 12, 2022 Filed Aug 16, 2022 21:36 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionCommon Shares 20,000 $3.10 $62,000.00
Disclosure

SEC source: 0001209191-22-046017 · doc4.xml · nonDerivative · entry 1

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 21:26 UTC GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039827 · doc4.xml · derivative · entry 1

GANNON STEVEN · CIK 0001643085 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 17:48 UTC GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039837 · doc4.xml · derivative · entry 1

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 21:34 UTC GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039831 · doc4.xml · derivative · entry 1

Machado Patrick · CIK 0001311210 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 21:40 UTC
PATOU GARYDirector
GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039833 · doc4.xml · derivative · entry 1

PATOU GARY · CIK 0001283535 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 17:23 UTC GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039824 · doc4.xml · derivative · entry 1

AZAB MOHAMMAD · CIK 0001309653 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 21:44 UTC GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039836 · doc4.xml · derivative · entry 1

Svoronos Dawn · CIK 0001574579 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 21:31 UTC GrantStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $30.11 $0.00
Disclosure

SEC source: 0001209191-22-039829 · doc4.xml · derivative · entry 1

GAROFALO ELIZABETH A. · CIK 0001826361 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Shares · 18,000 shares

Expires 2032-06-27

F1 · derivative.exercise_date: 100% of the common shares subject to the option will vest on the earlier of (i) the first anniversary of grant date and (ii) the day immediately preceding the day of the Issuer's next annual general meeting of shareholders.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 20:13 UTC
KENNEY CHRISTOPHER JOHNChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 125,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018449 · doc4.xml · derivative · entry 1

KENNEY CHRISTOPHER JOHN · CIK 0001880129 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Shares · 125,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 16:11 UTC
AULIN SHERRYChief Financial Officer
GrantStock Option (Right to Buy) · Derivative 125,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018445 · doc4.xml · derivative · entry 1

AULIN SHERRY · CIK 0001862144 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Shares · 125,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 16:20 UTC
PIMSTONE SIMON N.Director · Executive Chair
GrantStock Option (Right to Buy) · Derivative 25,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018457 · doc4.xml · derivative · entry 1

PIMSTONE SIMON N. · CIK 0001620084 · Director · Executive Chair

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Shares · 25,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 20:24 UTC
Von Seggern ChristopherChief Commercial Officer
GrantStock Option (Right to Buy) · Derivative 100,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018467 · doc4.xml · derivative · entry 1

Von Seggern Christopher · CIK 0001821192 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 20:21 UTC
ROBIN SHERRINGTONEVP, Strategy & Innovation
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018463 · doc4.xml · derivative · entry 1

ROBIN SHERRINGTON · CIK 0001619962 · EVP, Strategy & Innovation

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Shares · 75,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 20:15 UTC
MORTIMER IANDirector · PRESIDENT & CEO
GrantStock Option (Right to Buy) · Derivative 400,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018453 · doc4.xml · derivative · entry 1

MORTIMER IAN · CIK 0001619961 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 400,000

Underlying: Common Shares · 400,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 10, 2022 Filed Mar 14, 2022 20:10 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
GrantStock Option (Right to Buy) · Derivative 65,000 $0.00 Strike: $30.01 $0.00
Disclosure

SEC source: 0001209191-22-018440 · doc4.xml · derivative · entry 1

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Shares · 65,000 shares

Expires 2032-03-09

F1 · derivative.exercise_date: Vesting 25% on January 1, 2023 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 08, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $30.50 $76,250.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 19

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,135

Read SEC document
March 08, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $30.55 $76,375.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 18

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,635

F11 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.55 to $30.65, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein

Read SEC document
March 08, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $30.20 $75,500.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 17

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 188,135

Read SEC document
March 08, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $30.10 $75,250.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 16

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 190,635

Read SEC document
March 08, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $3.80 $9,500.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 15

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 193,135

F10 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.800 to $30.880, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 08, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,051 $30.60 $62,760.60
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 14

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 195,635

Read SEC document
March 08, 2022 Filed Mar 8, 2022 21:41 UTC Amendment SaleCommon Shares 2,500 $30.80 $77,000.00
Disclosure

SEC source: 0001209191-22-017418 · doc4a.xml · nonDerivative · entry 1

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 193,135

F1 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.800 to $30.880, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 20,576 $0.00 Strike: $3.67 $0.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · derivative · entry 21

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Shares · 20,576 shares

Expires 2022-03-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The exercise price was converted to U.S. dollars from $3.74 CAD using the closing rate of exchange on the Bank of Canada on the date of grant. The actual exercise price is the Canadian dollar amount regardless of the exchange rate on the day of exercise.

F12 · derivative.exercise_date: 25% of the shares subject to the Option vested on the one year anniversary of January 1, 2012 (the "2012 Vesting Commencement Date") and thereafter 1/48th of the shares subject to the Option vest on each monthly anniversary of the 2012 Vesting Commencement Date.

F13 · derivative.expiration_date: Expiration date differs from originally reported date due to an automatic extension provided by the option plan as a result of the original expiration date falling during a Company blackout period.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $30.55 $76,375.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 13

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 197,686

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 7,500 $30.50 $228,750.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 12

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200,186

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 2,500 $30.52 $76,300.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 11

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 207,686

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 4,516 $30.44 $137,467.04
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 10

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 210,186

F9 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.40 to $30.50, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 4,516 $30.45 $137,512.20
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 9

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 214,702

F8 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.4100 to $30.4750, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 4,517 $30.49 $137,723.33
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 8

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 219,218

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.480 to $30.645, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 5,037 $30.60 $154,132.20
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 7

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,735

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.4865 to $30.67, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC Tax withholdingCommon Shares 1,990 $30.23 $60,157.70
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 6

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 228,772

F5 · price: Represents the closing price of the Company's common shares on March 4, 2022, which was converted to a Canadian dollar amount for purposes of net settlement calculations.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 19:58 UTC Exercise / conversionCommon Shares 20,576 $3.67 $75,513.92
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 5

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 230,762

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The exercise price was converted to U.S. dollars from $3.74 CAD using the closing rate of exchange on the Bank of Canada on the date of grant. The actual exercise price is the Canadian dollar amount regardless of the exchange rate on the day of exercise.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionStock Option (Right to Buy) · Derivative 40,000 $0.00 Strike: $6.76 $0.00
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · derivative · entry 12

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Shares · 40,000 shares

Expires 2026-02-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Vesting 25% on February 9, 2017 and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionStock Option (Right to Buy) · Derivative 2,500 $0.00 Strike: $8.40 $0.00
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · derivative · entry 11

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Shares · 2,500 shares

Expires 2027-03-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Vesting 25% on January 1, 2018, and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
SaleCommon Shares 31,048 $30.54 $948,205.92
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 9

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.5161 to $30.6208, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
SaleCommon Shares 1,805 $30.62 $55,269.10
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 8

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,048

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Tax withholdingCommon Shares 8,952 $30.23 $270,618.96
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 7

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,853

F3 · price: Represents the closing price of the Company's common shares on March 4, 2022 which was converted to a Canadian dollar amount for purposes of net settlement calculations.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionCommon Shares 40,000 $6.76 $270,400.00
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 6

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,805

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Tax withholdingCommon Shares 695 $30.23 $21,009.85
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 5

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,805

F3 · price: Represents the closing price of the Company's common shares on March 4, 2022 which was converted to a Canadian dollar amount for purposes of net settlement calculations.

Read SEC document
March 07, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionCommon Shares 2,500 $8.40 $21,000.00
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 4

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 04, 2022 Filed Mar 8, 2022 19:58 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 10,288 $0.00 Strike: $3.67 $0.00
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · derivative · entry 20

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Shares · 10,288 shares

Expires 2022-03-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The exercise price was converted to U.S. dollars from $3.74 CAD using the closing rate of exchange on the Bank of Canada on the date of grant. The actual exercise price is the Canadian dollar amount regardless of the exchange rate on the day of exercise.

F12 · derivative.exercise_date: 25% of the shares subject to the Option vested on the one year anniversary of January 1, 2012 (the "2012 Vesting Commencement Date") and thereafter 1/48th of the shares subject to the Option vest on each monthly anniversary of the 2012 Vesting Commencement Date.

F13 · derivative.expiration_date: Expiration date differs from originally reported date due to an automatic extension provided by the option plan as a result of the original expiration date falling during a Company blackout period.

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March 04, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 4,793 $30.56 $146,474.08
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 4

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 210,186

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.53 to $30.61, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

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March 04, 2022 Filed Mar 8, 2022 19:58 UTC SaleCommon Shares 4,532 $30.66 $138,951.12
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 3

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 214,979

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.49 to $30.97, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

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March 04, 2022 Filed Mar 8, 2022 19:58 UTC Tax withholdingCommon Shares 963 $31.42 $30,257.46
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 2

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 219,511

F2 · price: Represents the closing price of the Company's common shares on March 3, 2022, which was converted to a Canadian dollar amount for purposes of net settlement calculations.

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March 04, 2022 Filed Mar 8, 2022 19:58 UTC Exercise / conversionCommon Shares 10,288 $3.67 $37,756.96
Disclosure

SEC source: 0001209191-22-017341 · doc4.xml · nonDerivative · entry 1

PIMSTONE SIMON N. · CIK 0001620084 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 220,474

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The exercise price was converted to U.S. dollars from $3.74 CAD using the closing rate of exchange on the Bank of Canada on the date of grant. The actual exercise price is the Canadian dollar amount regardless of the exchange rate on the day of exercise.

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March 04, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionStock Option (Right to Buy) · Derivative 25,000 $0.00 Strike: $8.40 $0.00
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · derivative · entry 10

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Shares · 25,000 shares

Expires 2027-03-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Vesting 25% on January 1, 2018, and 75% vesting thereafter over the course of the next 3 years, in equal amounts, on the last day of each month.

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March 04, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
SaleCommon Shares 18,315 $30.79 $563,918.85
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 3

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $30.21 to $31.0296, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

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March 04, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Tax withholdingCommon Shares 6,685 $31.42 $210,042.70
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 2

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,315

F1 · price: Represents the closing price of the Company's common shares on March 3, 2022 which was converted to a Canadian dollar amount for purposes of net settlement calculations.

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March 04, 2022 Filed Mar 9, 2022 00:32 UTC
EMPFIELD JAMES R.EVP, Drug Discovery
Exercise / conversionCommon Shares 25,000 $8.40 $210,000.00
Disclosure

SEC source: 0001209191-22-017316 · doc4.xml · nonDerivative · entry 1

EMPFIELD JAMES R. · CIK 0001665430 · EVP, Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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March 04, 2022 Filed Mar 9, 2022 00:35 UTC
ROBIN SHERRINGTONEVP, Strategy & Innovation
Exercise / conversionStock Option (Right to Buy) · Derivative 6,172 $0.00 Strike: $3.67 $0.00
Disclosure

SEC source: 0001209191-22-017318 · doc4.xml · derivative · entry 9

ROBIN SHERRINGTON · CIK 0001619962 · EVP, Strategy & Innovation

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Shares · 6,172 shares

Expires 2022-03-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The exercise price was converted to U.S. dollars from $3.74 CAD using the closing rate of exchange on the Bank of Canada on the date of grant. The actual exercise price is the Canadian dollar amount regardless of the exchange rate on the day of exercise.

F8 · derivative.exercise_date: 25% of the shares subject to the Option vested on the one year anniversary of January 1, 2012 (the "Second 2012 Vesting Commencement Date") and thereafter 1/48th of the shares subject to the Option vest on each monthly anniversary of the Second 2012 Vesting Commencement Date

F7 · derivative.expiration_date: Expiration date differs from originally reported date due to an automatic extension provided by the option plan as a result of the original expiration date falling during a Company blackout period.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.