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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 01, 2017 Filed Jun 5, 2017 22:05 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 10,195 $38.80 $395,566.00
Disclosure

SEC source: 0001209191-17-037922 · doc4.xml · nonDerivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 224,791

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:05 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 9,062 $51.75 $468,958.50
Disclosure

SEC source: 0001209191-17-037922 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 214,596

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:05 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 23,789 $37.86 $900,651.54
Disclosure

SEC source: 0001209191-17-037922 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 205,534

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:05 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 18,124 $48.74 $883,363.76
Disclosure

SEC source: 0001209191-17-037922 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 181,745

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:05 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 37,383 $45.11 $1,686,347.13
Disclosure

SEC source: 0001209191-17-037922 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 163,621

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:06 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 13,594 $0.00 Strike: $53.74 $0.00
Disclosure

SEC source: 0001209191-17-037923 · doc4.xml · derivative · entry 7

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 13,594 shares

Expires 2022-09-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:06 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 13,594 $124.00 $1,685,656.00
Disclosure

SEC source: 0001209191-17-037923 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,467

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $124.00 (range $124.00 to $124.04).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:06 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 13,594 $53.74 $730,541.56
Disclosure

SEC source: 0001209191-17-037923 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,061

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:07 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 5,155 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-17-037925 · doc4.xml · derivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,908

Underlying: Common Stock · 5,155 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/15/2014.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:07 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 5,155 $126.87 $654,014.85
Disclosure

SEC source: 0001209191-17-037925 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,511

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:07 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 5,155 $96.87 $499,364.85
Disclosure

SEC source: 0001209191-17-037925 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 127,666

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:08 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 30,500 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-17-037926 · doc4.xml · derivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,500 shares

Expires 2021-07-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:08 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 30,500 $125.00 $3,812,500.00
Disclosure

SEC source: 0001209191-17-037926 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,335

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:08 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 30,500 $51.75 $1,578,375.00
Disclosure

SEC source: 0001209191-17-037926 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,835

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:09 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 3,867 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-17-037927 · doc4.xml · derivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,312

Underlying: Common Stock · 3,867 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:09 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 3,867 $127.31 $492,307.77
Disclosure

SEC source: 0001209191-17-037927 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,071

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 22:09 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 3,867 $77.31 $298,957.77
Disclosure

SEC source: 0001209191-17-037927 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,938

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 15, 2017 Filed May 17, 2017 20:21 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 271 $114.64 $31,067.44
Disclosure

SEC source: 0001209191-17-033063 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,071

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2017 Filed May 17, 2017 20:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 116 $114.37 $13,266.92
Disclosure

SEC source: 0001209191-17-033067 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,335

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2017 Filed May 17, 2017 20:24 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 294 $114.92 $33,786.48
Disclosure

SEC source: 0001209191-17-033072 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 126,238

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $114.92 (range $114.37 to $115.21).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 15, 2017 Filed May 17, 2017 20:25 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 181 $114.37 $20,700.97
Disclosure

SEC source: 0001209191-17-033077 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,011

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
May 02, 2017 Filed May 4, 2017 12:51 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 8,979 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-17-029869 · doc4.xml · derivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,756

Underlying: Common Stock · 8,979 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/02/2016.

Read SEC document
May 02, 2017 Filed May 4, 2017 12:51 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 8,979 $121.05 $1,086,907.95
Disclosure

SEC source: 0001209191-17-029869 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,511

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

Read SEC document
May 02, 2017 Filed May 4, 2017 12:51 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 8,979 $91.05 $817,537.95
Disclosure

SEC source: 0001209191-17-029869 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,490

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $34.05 $0.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · derivative · entry 10

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2019-07-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 20,000 $0.00 Strike: $34.24 $0.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · derivative · entry 9

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,000 shares

Expires 2020-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 1,527 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · derivative · entry 8

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,527 shares

Expires 2020-12-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 88,507 $0.00 Strike: $29.98 $0.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · derivative · entry 7

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 124,601

Underlying: Common Stock · 88,507 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 157,200 $119.50 $18,785,400.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · nonDerivative · entry 5

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 289,479

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $119.50 (range $119.50 to $119.60).

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionCommon Stock 30,000 $34.05 $1,021,500.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 446,679

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionCommon Stock 20,000 $34.24 $684,800.00
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · nonDerivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 416,679

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionCommon Stock 1,527 $34.39 $52,513.53
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 396,679

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2017 Filed Apr 28, 2017 20:44 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionCommon Stock 88,507 $29.98 $2,653,439.86
Disclosure

SEC source: 0001209191-17-028749 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 395,152

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2017 Filed May 2, 2017 21:17 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 28,320 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-17-029272 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 28,320 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 28, 2017 Filed May 2, 2017 21:17 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 28,320 $119.50 $3,384,240.00
Disclosure

SEC source: 0001209191-17-029272 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,247

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

Read SEC document
April 28, 2017 Filed May 2, 2017 21:17 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 28,320 $45.11 $1,277,515.20
Disclosure

SEC source: 0001209191-17-029272 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 159,567

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2017 Filed May 2, 2017 21:18 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 7,500 $0.00 Strike: $63.14 $0.00
Disclosure

SEC source: 0001209191-17-029274 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2022-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 28, 2017 Filed May 2, 2017 21:18 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 7,500 $120.00 $900,000.00
Disclosure

SEC source: 0001209191-17-029274 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,011

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
April 28, 2017 Filed May 2, 2017 21:18 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionCommon Stock 7,500 $63.14 $473,550.00
Disclosure

SEC source: 0001209191-17-029274 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,511

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 17, 2017 Filed Apr 19, 2017 21:10 UTC GrantDeferred Stock Units · Derivative 360.011 $114.58 $41,250.06
Disclosure

SEC source: 0001209191-17-027500 · doc4.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,334.246

Underlying: Common Stock · 360.011 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 20:09 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock · Derivative 8,021 $0.00 Strike: $73.51 $0.00
Disclosure

SEC source: 0001209191-17-026241 · doc4.xml · derivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,313

Underlying: Common Stock · 8,021 shares

Expires 2024-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 01/02/2014.

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April 05, 2017 Filed Apr 7, 2017 20:09 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 8,021 $114.00 $914,394.00
Disclosure

SEC source: 0001209191-17-026241 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,511

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 20:09 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 8,021 $73.51 $589,623.71
Disclosure

SEC source: 0001209191-17-026241 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 130,532

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 03, 2017 Filed Apr 5, 2017 20:55 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,291 $0.00 Strike: $73.51 $0.00
Disclosure

SEC source: 0001209191-17-025700 · doc4.xml · derivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,334

Underlying: Common Stock · 2,291 shares

Expires 2024-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 01/02/2014.

Read SEC document
April 03, 2017 Filed Apr 5, 2017 20:55 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 200 $110.09 $22,018.00
Disclosure

SEC source: 0001209191-17-025700 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,511

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

Read SEC document
April 03, 2017 Filed Apr 5, 2017 20:55 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 600 $109.32 $65,592.00
Disclosure

SEC source: 0001209191-17-025700 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,711

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $109.32 (range $109.09 to $109.70).

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April 03, 2017 Filed Apr 5, 2017 20:55 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,491 $108.50 $161,773.50
Disclosure

SEC source: 0001209191-17-025700 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 123,311

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $108.50 (range $108.07 to $108.84).

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April 03, 2017 Filed Apr 5, 2017 20:55 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 2,291 $73.51 $168,411.41
Disclosure

SEC source: 0001209191-17-025700 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 124,802

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 29, 2017 Filed Mar 31, 2017 20:08 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 13,750 $0.00 Strike: $73.51 $0.00
Disclosure

SEC source: 0001209191-17-023840 · doc4.xml · derivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,625

Underlying: Common Stock · 13,750 shares

Expires 2024-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 01/02/2014.

Read SEC document
March 29, 2017 Filed Mar 31, 2017 20:08 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 13,750 $106.65 $1,466,437.50
Disclosure

SEC source: 0001209191-17-023840 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,511

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $106.65 (range $106.30 to $107.00).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.