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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 07, 2017 Filed Aug 9, 2017 20:33 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 1,250 $156.02 $195,025.00
Disclosure

SEC source: 0001209191-17-048255 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $156.02 (range $155.87 to $156.26).

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:33 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 2,600 $155.29 $403,754.00
Disclosure

SEC source: 0001209191-17-048255 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,138

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $155.29 (range $154.82 to $155.80).

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:33 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 400 $154.09 $61,636.00
Disclosure

SEC source: 0001209191-17-048255 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,738

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $154.09 (range $153.67 to $154.50).

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:33 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 4,250 $77.31 $328,567.50
Disclosure

SEC source: 0001209191-17-048255 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,138

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:36 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,250 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-17-048258 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

Underlying: Common Stock · 4,250 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/5/2014.

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:36 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 4,250 $152.88 $649,740.00
Disclosure

SEC source: 0001209191-17-048258 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,117

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:36 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 4,250 $77.31 $328,567.50
Disclosure

SEC source: 0001209191-17-048258 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,367

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:38 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 1,289 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-17-048259 · doc4.xml · derivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,578

Underlying: Common Stock · 1,289 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/5/2014.

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:38 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 1,289 $152.88 $197,062.32
Disclosure

SEC source: 0001209191-17-048259 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 07, 2017 Filed Aug 9, 2017 20:38 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 1,289 $77.31 $99,652.59
Disclosure

SEC source: 0001209191-17-048259 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,923

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 3,594 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · derivative · entry 11

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,563

Underlying: Common Stock · 3,594 shares

Expires 2025-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2015.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 500 $155.15 $77,575.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 9

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $155.15 (range $154.73 to $155.53).

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 2,494 $154.21 $384,599.74
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 8

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,924

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $154.21 (range $153.71 to $154.64).

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 600 $153.29 $91,974.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 7

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,418

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $153.29 (range $152.63 to $153.55).

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 3,594 $109.14 $392,249.16
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 6

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:45 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-17-047723 · doc4.xml · derivative · entry 3

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,619

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:45 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 2,330 $155.72 $362,827.60
Disclosure

SEC source: 0001209191-17-047723 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,809

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:45 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-17-047723 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,139

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:53 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,250 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-17-047736 · doc4.xml · derivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,500

Underlying: Common Stock · 4,250 shares

Expires 2025-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2015.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:53 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 4,250 $155.72 $661,810.00
Disclosure

SEC source: 0001209191-17-047736 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,117

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 03, 2017 Filed Aug 4, 2017 20:53 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 4,250 $109.14 $463,845.00
Disclosure

SEC source: 0001209191-17-047736 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,367

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:36 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 1,289 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-17-047711 · doc4.xml · derivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,891

Underlying: Common Stock · 1,289 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:36 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 1,289 $151.80 $195,670.20
Disclosure

SEC source: 0001209191-17-047711 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:36 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 1,289 $91.05 $117,363.45
Disclosure

SEC source: 0001209191-17-047711 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,923

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · derivative · entry 10

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,960

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 296 $156.24 $46,247.04
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $156.24 (range $155.94 to $156.40).

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 400 $154.89 $61,956.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,720

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $154.89 (range $154.70 to $155.40).

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 600 $153.93 $92,358.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,120

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $153.93 (range $153.31 to $154.30).

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 500 $152.50 $76,250.00
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,720

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $152.50 (range $152.00 to $152.88).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:42 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-17-047716 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,220

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:48 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,155 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-17-047729 · doc4.xml · derivative · entry 7

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,552

Underlying: Common Stock · 2,155 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:48 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 455 $156.09 $71,020.95
Disclosure

SEC source: 0001209191-17-047729 · doc4.xml · nonDerivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $156.09 (range $155.49 to $156.40).

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:48 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 700 $154.55 $108,185.00
Disclosure

SEC source: 0001209191-17-047729 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,343

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $154.55 (range $154.20 to $154.93).

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:48 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 500 $153.57 $76,785.00
Disclosure

SEC source: 0001209191-17-047729 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,043

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $153.57 (range $153.08 to $154.05).

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:48 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 500 $152.49 $76,245.00
Disclosure

SEC source: 0001209191-17-047729 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,543

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $152.49 (range $152.00 to $152.76).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 02, 2017 Filed Aug 4, 2017 20:48 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 2,155 $91.05 $196,212.75
Disclosure

SEC source: 0001209191-17-047729 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,043

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:44 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-17-047127 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,125 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

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July 31, 2017 Filed Aug 2, 2017 20:44 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 2,125 $152.99 $325,103.75
Disclosure

SEC source: 0001209191-17-047127 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,117

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

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July 31, 2017 Filed Aug 2, 2017 20:44 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 2,125 $83.36 $177,140.00
Disclosure

SEC source: 0001209191-17-047127 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 123,242

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:47 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 860 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-17-047130 · doc4.xml · derivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 860 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:47 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 860 $152.99 $131,571.40
Disclosure

SEC source: 0001209191-17-047130 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:47 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 860 $83.36 $71,689.60
Disclosure

SEC source: 0001209191-17-047130 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,494

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:51 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-17-047132 · doc4.xml · derivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,125 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:51 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 100 $154.13 $15,413.00
Disclosure

SEC source: 0001209191-17-047132 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:51 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 1,100 $153.30 $168,630.00
Disclosure

SEC source: 0001209191-17-047132 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,988

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $153.30 (range $152.96 to $153.72).

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:51 UTC
SMITH IAN FEVP, CFO & COO
SaleCommon Stock 925 $152.24 $140,822.00
Disclosure

SEC source: 0001209191-17-047132 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,088

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $152.24 (range $151.80 to $152.79).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:51 UTC
SMITH IAN FEVP, CFO & COO
Exercise / conversionCommon Stock 2,125 $83.36 $177,140.00
Disclosure

SEC source: 0001209191-17-047132 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:56 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 11,063 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-17-047139 · doc4.xml · derivative · entry 6

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,313

Underlying: Common Stock · 11,063 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:56 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 700 $154.05 $107,835.00
Disclosure

SEC source: 0001209191-17-047139 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 257,392

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $154.05 (range $153.91 to $154.27).

Read SEC document
July 31, 2017 Filed Aug 2, 2017 20:56 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 5,000 $153.24 $766,200.00
Disclosure

SEC source: 0001209191-17-047139 · doc4.xml · nonDerivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 258,092

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $153.24 (range $152.79 to $153.78).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.