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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
December 27, 2017 Filed Dec 28, 2017 21:31 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 1,289 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-17-067583 · doc4.xml · derivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,289

Underlying: Common Stock · 1,289 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
December 27, 2017 Filed Dec 28, 2017 21:31 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 1,289 $152.31 $196,327.59
Disclosure

SEC source: 0001209191-17-067583 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
December 27, 2017 Filed Dec 28, 2017 21:31 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 1,289 $77.31 $99,652.59
Disclosure

SEC source: 0001209191-17-067583 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,923

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 20, 2017 Filed Jan 17, 2018 21:42 UTC GiftCommon Stock 10,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-003972 · doc5.xml · nonDerivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,398

F1 · kind: Represents a gift to a charitable foundation.

Read SEC document
December 11, 2017 Filed Dec 11, 2017 23:30 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 5,198 $143.39 $745,341.22
Disclosure

SEC source: 0001209191-17-065094 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,497

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $143.39 (range $142.90 to $143.85).

Read SEC document
December 11, 2017 Filed Dec 11, 2017 23:30 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 12,134 $142.21 $1,725,576.14
Disclosure

SEC source: 0001209191-17-065094 · doc4.xml · nonDerivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 137,695

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $142.21 (range $141.86 to $142.79).

Read SEC document
December 11, 2017 Filed Dec 11, 2017 23:30 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 87,578 $141.35 $12,379,150.30
Disclosure

SEC source: 0001209191-17-065094 · doc4.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,829

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $141.35 (range $140.86 to $141.85).

Read SEC document
December 11, 2017 Filed Dec 11, 2017 23:30 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 20,090 $140.31 $2,818,827.90
Disclosure

SEC source: 0001209191-17-065094 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 237,407

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $140.31 (range $139.85 to 140.84).

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 21:37 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 221 $147.29 $32,551.09
Disclosure

SEC source: 0001209191-17-061506 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,952

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 21:41 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 83 $147.29 $12,225.07
Disclosure

SEC source: 0001209191-17-061524 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,710

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 21:44 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 7 $147.29 $1,031.03
Disclosure

SEC source: 0001209191-17-061525 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 21:46 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 23 $147.29 $3,387.67
Disclosure

SEC source: 0001209191-17-061526 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 21:48 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 206 $149.80 $30,858.80
Disclosure

SEC source: 0001209191-17-061528 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,011

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $149.80 (range $149.28 to $150.25).

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 21:48 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 100 $147.71 $14,771.00
Disclosure

SEC source: 0001209191-17-061528 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,217

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 15, 2017 Filed Dec 6, 2017 22:40 UTC Amendment
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 48 $147.29 $7,069.92
Disclosure

SEC source: 0001209191-17-064229 · doc4a.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,952

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

F2 · shares: This amendment corrects an error by our external equity plan administrator and reduces the number of shares sold from 221 shares to 48 shares.

Read SEC document
November 06, 2017 Filed Nov 7, 2017 22:15 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,250 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-17-059636 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,250

Underlying: Common Stock · 4,250 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/5/2014.

Read SEC document
November 06, 2017 Filed Nov 7, 2017 22:15 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 4,250 $148.17 $629,722.50
Disclosure

SEC source: 0001209191-17-059636 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,952

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 06, 2017 Filed Nov 7, 2017 22:15 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 4,250 $77.31 $328,567.50
Disclosure

SEC source: 0001209191-17-059636 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 06, 2017 Filed Nov 7, 2017 22:26 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy) · Derivative 4,250 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-17-059638 · doc4.xml · derivative · entry 7

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,250

Underlying: Common Stock · 4,250 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/5/2014.

Read SEC document
November 06, 2017 Filed Nov 7, 2017 22:26 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 4,250 $150.00 $637,500.00
Disclosure

SEC source: 0001209191-17-059638 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 06, 2017 Filed Nov 7, 2017 22:26 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 4,250 $77.31 $328,567.50
Disclosure

SEC source: 0001209191-17-059638 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,138

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 03, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 3,594 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · derivative · entry 8

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,969

Underlying: Common Stock · 3,594 shares

Expires 2025-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2015.

Read SEC document
November 03, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 3,594 $144.69 $520,015.86
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · nonDerivative · entry 6

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $144.69 (range $144.19 to $144.90).

Read SEC document
November 03, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 3,594 $109.14 $392,249.16
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · nonDerivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:12 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 7,073 $0.00 Strike: $93.51 $0.00
Disclosure

SEC source: 0001209191-17-059633 · doc4.xml · derivative · entry 3

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,073 shares

Expires 2026-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:12 UTC SaleCommon Stock 7,073 $143.05 $1,011,792.65
Disclosure

SEC source: 0001209191-17-059633 · doc4.xml · nonDerivative · entry 2

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,953

F1 · kind: Transaction made pursuant to Dr. Bhatia's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:12 UTC Exercise / conversionCommon Stock 7,073 $93.51 $661,396.23
Disclosure

SEC source: 0001209191-17-059633 · doc4.xml · nonDerivative · entry 1

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,026

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:23 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-17-059637 · doc4.xml · derivative · entry 3

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,289

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:23 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 2,330 $149.50 $348,335.00
Disclosure

SEC source: 0001209191-17-059637 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,809

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:23 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-17-059637 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,139

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:26 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,155 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-17-059638 · doc4.xml · derivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,397

Underlying: Common Stock · 2,155 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:26 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 2,155 $150.00 $323,250.00
Disclosure

SEC source: 0001209191-17-059638 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

Read SEC document
November 03, 2017 Filed Nov 7, 2017 22:26 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 2,155 $91.05 $196,212.75
Disclosure

SEC source: 0001209191-17-059638 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,043

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 02, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · derivative · entry 7

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,164

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
November 02, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 300 $145.89 $43,767.00
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $145.89 (range $145.63 to $146.04).

Read SEC document
November 02, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,096 $144.89 $158,799.44
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,724

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $144.89 (range $144.48 to $145.18).

Read SEC document
November 02, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 400 $143.54 $57,416.00
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,820

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $143.54 (range $142.98 to $143.81).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 02, 2017 Filed Nov 6, 2017 22:50 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-17-059474 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,220

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 100 $149.34 $14,934.00
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 8

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,710

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 1,000 $148.35 $148,350.00
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 7

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,810

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $148.35 (range $148.19 to $148.70).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 2,200 $147.70 $324,940.00
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 6

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,810

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $147.70 (range $147.18 to $148.15).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 3,200 $146.53 $468,896.00
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,010

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $146.53 (range $146.16 to $147.14).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 12,438 $145.26 $1,806,743.88
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,210

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $145.26 (range $144.93 to $145.87).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 17,362 $144.47 $2,508,288.14
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,648

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $144.47 (range $143.90 to $144.89).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 2,800 $143.49 $401,772.00
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,010

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $143.49 (range $142.87 to $143.85).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:12 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 900 $142.40 $128,160.00
Disclosure

SEC source: 0001209191-17-058477 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 89,810

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $142.40 (range $141.83 to $142.70).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 200 $149.34 $29,868.00
Disclosure

SEC source: 0001209191-17-058479 · doc4.xml · nonDerivative · entry 8

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,400 $148.40 $207,760.00
Disclosure

SEC source: 0001209191-17-058479 · doc4.xml · nonDerivative · entry 7

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,624

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $148.40 (range $148.19 to $148.70).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 3,400 $147.75 $502,350.00
Disclosure

SEC source: 0001209191-17-058479 · doc4.xml · nonDerivative · entry 6

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,024

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $147.75 (range $147.18 to $148.15).

Read SEC document
October 31, 2017 Filed Oct 31, 2017 22:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 4,700 $146.52 $688,644.00
Disclosure

SEC source: 0001209191-17-058479 · doc4.xml · nonDerivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $146.52 (range $146.16 to $147.14).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.