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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 700 $159.35 $111,545.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,163

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $159.35 (range $159.27 to $159.45).

Read SEC document
January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 13,312 $158.59 $2,111,150.08
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,863

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $158.59 (range $158.20 to $159.10).

Read SEC document
January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 18,410 $157.67 $2,902,704.70
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,175

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $157.67 (range $157.18 to $158.17).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 13,750 $83.36 $1,146,200.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,585

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 18,672 $77.31 $1,443,532.32
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,835

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:34 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-003955 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,250

Underlying: Common Stock · 2,125 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/15/2014.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:34 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 2,125 $158.28 $336,345.00
Disclosure

SEC source: 0001209191-18-003955 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,952

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:34 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 2,125 $96.87 $205,848.75
Disclosure

SEC source: 0001209191-18-003955 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,077

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:38 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,719 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-003958 · doc4.xml · derivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,438

Underlying: Common Stock · 1,719 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/15/2014.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:38 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 300 $159.04 $47,712.00
Disclosure

SEC source: 0001209191-18-003958 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:38 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 900 $157.54 $141,786.00
Disclosure

SEC source: 0001209191-18-003958 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,724

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $157.54 (range $156.95 to $157.83).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:38 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 519 $155.80 $80,860.20
Disclosure

SEC source: 0001209191-18-003958 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,624

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $155.80 (range $155.77 to $155.91).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:38 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 1,719 $96.87 $166,519.53
Disclosure

SEC source: 0001209191-18-003958 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,143

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:40 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-003963 · doc4.xml · derivative · entry 7

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,250

Underlying: Common Stock · 2,125 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/15/2014.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:40 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 500 $159.29 $79,645.00
Disclosure

SEC source: 0001209191-18-003963 · doc4.xml · nonDerivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,888

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $159.29 (range $158.96 to $159.65).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:40 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 400 $158.11 $63,244.00
Disclosure

SEC source: 0001209191-18-003963 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,388

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $158.11 (range $157.77 to $158.67).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:40 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 400 $157.02 $62,808.00
Disclosure

SEC source: 0001209191-18-003963 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,788

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $157.02 (range $156.62 to $157.50).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:40 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 825 $155.80 $128,535.00
Disclosure

SEC source: 0001209191-18-003963 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,188

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $155.80 (range $155.32 to $156.26).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:40 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 2,125 $96.87 $205,848.75
Disclosure

SEC source: 0001209191-18-003963 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:43 UTC GrantDeferred Stock Units · Derivative 261.905 $157.50 $41,250.04
Disclosure

SEC source: 0001209191-18-003974 · doc4.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,119.469

Underlying: Common Stock · 261.905 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) the termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) the termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) the termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 55,313 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · derivative · entry 10

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 55,313 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: Fully vested.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 44,250 $0.00 Strike: $48.74 $0.00
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · derivative · entry 9

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 44,250 shares

Expires 2022-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: Fully vested.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 7,995 $159.39 $1,274,323.05
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 7

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,497

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $159.39 (range $159.18 to $159.75).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 17,918 $158.79 $2,845,199.22
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 6

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,492

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $158.79 (range $158.18 to $159.16).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 11,471 $157.67 $1,808,632.57
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 5

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,410

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $157.67 (range $157.18 to $158.17).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 19,808 $156.62 $3,102,328.96
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 169,881

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $156.62 (range $156.18 to $157.17).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 42,371 $155.77 $6,600,130.67
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 189,689

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $155.77 (range $155.18 to $156.17).

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionCommon Stock 55,313 $45.11 $2,495,169.43
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 232,060

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:45 UTC
LEIDEN JEFFREY MDirector · CEO & President
Exercise / conversionCommon Stock 44,250 $48.74 $2,156,745.00
Disclosure

SEC source: 0001209191-18-003981 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,747

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:46 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 3,955 $159.41 $630,466.55
Disclosure

SEC source: 0001209191-18-003986 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,761

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $159.41 (range $159.21 to $159.65).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:46 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 10,585 $158.82 $1,681,109.70
Disclosure

SEC source: 0001209191-18-003986 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,716

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $158.82 (range $158.21 to $159.20).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:46 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 6,130 $157.71 $966,762.30
Disclosure

SEC source: 0001209191-18-003986 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,301

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $157.71 (range $157.20 to $158.19).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:46 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 11,767 $156.63 $1,843,065.21
Disclosure

SEC source: 0001209191-18-003986 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,431

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $156.63 (range $156.19 to $157.18).

Read SEC document
January 16, 2018 Filed Jan 17, 2018 21:46 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 23,813 $155.77 $3,709,351.01
Disclosure

SEC source: 0001209191-18-003986 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,198

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $155.77 (range $155.19 to $156.17).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 12, 2018 Filed Jan 16, 2018 22:01 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $90.29 $0.00
Disclosure

SEC source: 0001209191-18-003628 · doc4.xml · derivative · entry 3

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,250

Underlying: Common Stock · 2,125 shares

Expires 2026-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/12/2016.

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January 12, 2018 Filed Jan 16, 2018 22:01 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 2,125 $157.16 $333,965.00
Disclosure

SEC source: 0001209191-18-003628 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,943

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

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January 12, 2018 Filed Jan 16, 2018 22:01 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionCommon Stock 2,125 $90.29 $191,866.25
Disclosure

SEC source: 0001209191-18-003628 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,068

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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January 11, 2018 Filed Jan 12, 2018 21:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,250 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-18-003419 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,250

Underlying: Common Stock · 4,250 shares

Expires 2025-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2015.

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January 11, 2018 Filed Jan 12, 2018 21:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 4,250 $159.00 $675,750.00
Disclosure

SEC source: 0001209191-18-003419 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,952

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

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January 11, 2018 Filed Jan 12, 2018 21:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 4,250 $109.14 $463,845.00
Disclosure

SEC source: 0001209191-18-003419 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 05, 2018 Filed Jan 9, 2018 22:33 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 10,753 $0.00 Strike: $126.68 $0.00
Disclosure

SEC source: 0001209191-18-002982 · doc4.xml · derivative · entry 3

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,247

Underlying: Common Stock · 10,753 shares

Expires 2025-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 06/04/2015.

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January 05, 2018 Filed Jan 9, 2018 22:33 UTC SaleCommon Stock 10,753 $156.00 $1,677,468.00
Disclosure

SEC source: 0001209191-18-002982 · doc4.xml · nonDerivative · entry 2

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,953

F1 · kind: Transaction made pursuant to Dr. Bhatia's company-approved trading plan under Rule 10b5-1.

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January 05, 2018 Filed Jan 9, 2018 22:33 UTC Exercise / conversionCommon Stock 10,753 $126.68 $1,362,190.04
Disclosure

SEC source: 0001209191-18-002982 · doc4.xml · nonDerivative · entry 1

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,706

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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January 02, 2018 Filed Jan 3, 2018 21:49 UTC
Graney ThomasChief Financial Officer
SaleCommon Stock 777 $149.95 $116,511.15
Disclosure

SEC source: 0001209191-18-000968 · doc4.xml · nonDerivative · entry 1

Graney Thomas · CIK 0001618275 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,789

F1 · kind: Transaction made pursuant to Mr. Graney's company-approved trading plan under Rule 10b5-1.

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January 02, 2018 Filed Jan 3, 2018 21:56 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 3,438 $0.00 Strike: $73.51 $0.00
Disclosure

SEC source: 0001209191-18-001000 · doc4.xml · derivative · entry 6

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,438 shares

Expires 2024-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: Fully vested.

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January 02, 2018 Filed Jan 3, 2018 21:56 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 863 $152.80 $131,866.40
Disclosure

SEC source: 0001209191-18-001000 · doc4.xml · nonDerivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,424

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $152.80 (range $152.70 to $153.03).

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January 02, 2018 Filed Jan 3, 2018 21:56 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,600 $152.06 $243,296.00
Disclosure

SEC source: 0001209191-18-001000 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,287

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $152.06 (range $151.70 to $152.69).

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January 02, 2018 Filed Jan 3, 2018 21:56 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 675 $150.87 $101,837.25
Disclosure

SEC source: 0001209191-18-001000 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,887

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $150.87 (range $150.53 to $151.50).

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January 02, 2018 Filed Jan 3, 2018 21:56 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 300 $149.65 $44,895.00
Disclosure

SEC source: 0001209191-18-001000 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,562

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $149.65 (range $149.41 to $149.92).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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January 02, 2018 Filed Jan 3, 2018 21:56 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 3,438 $73.51 $252,727.38
Disclosure

SEC source: 0001209191-18-001000 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,862

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.