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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 02, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · derivative · entry 7

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,368

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 100 $169.49 $16,949.00
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · nonDerivative · entry 6

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,524

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 100 $168.06 $16,806.00
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · nonDerivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,624

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 996 $166.10 $165,435.60
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,724

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $166.10 (range $165.81 to $166.43).

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 600 $165.23 $99,138.00
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,720

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $165.23 (range $164.80 to $165.67).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,320

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:47 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-007618 · doc4.xml · derivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,368

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:47 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 100 $169.49 $16,949.00
Disclosure

SEC source: 0001209191-18-007618 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,761

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:47 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 100 $167.81 $16,781.00
Disclosure

SEC source: 0001209191-18-007618 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,861

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:47 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 996 $166.12 $165,455.52
Disclosure

SEC source: 0001209191-18-007618 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,961

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $166.12 (range $165.81 to $166.43).

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:47 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 600 $165.24 $99,144.00
Disclosure

SEC source: 0001209191-18-007618 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,957

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $165.24 (range $164.80 to $165.71).

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 02, 2018 Filed Feb 5, 2018 22:47 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-18-007618 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,557

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 22:35 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 3,450 $174.11 $600,679.50
Disclosure

SEC source: 0001209191-18-007604 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,493

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 22:39 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 8,594 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-007614 · doc4.xml · derivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,719

Underlying: Common Stock · 8,594 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/15/2014.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 22:39 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 8,594 $174.11 $1,496,301.34
Disclosure

SEC source: 0001209191-18-007614 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 22:39 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 8,594 $96.87 $832,500.78
Disclosure

SEC source: 0001209191-18-007614 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,228

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 22:43 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,900 $167.44 $318,136.00
Disclosure

SEC source: 0001209191-18-007617 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,524

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 29, 2018 Filed Jan 30, 2018 22:10 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 15,085 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-006063 · doc4.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,397

Underlying: Common Stock · 15,085 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
January 29, 2018 Filed Jan 30, 2018 22:10 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 15,085 $170.00 $2,564,450.00
Disclosure

SEC source: 0001209191-18-006063 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,163

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 29, 2018 Filed Jan 30, 2018 22:10 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 15,085 $91.05 $1,373,489.25
Disclosure

SEC source: 0001209191-18-006063 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,248

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 24, 2018 Filed Jan 26, 2018 21:46 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,659 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-005638 · doc4.xml · derivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,193

Underlying: Common Stock · 4,659 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
January 24, 2018 Filed Jan 26, 2018 21:46 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,310 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-005638 · doc4.xml · derivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,397

Underlying: Common Stock · 4,310 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
January 24, 2018 Filed Jan 26, 2018 21:46 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 8,969 $169.00 $1,515,761.00
Disclosure

SEC source: 0001209191-18-005638 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,952

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 24, 2018 Filed Jan 26, 2018 21:46 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 4,659 $86.52 $403,096.68
Disclosure

SEC source: 0001209191-18-005638 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,921

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 24, 2018 Filed Jan 26, 2018 21:46 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 4,310 $91.05 $392,425.50
Disclosure

SEC source: 0001209191-18-005638 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,262

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 1,719 $0.00 Strike: $90.29 $0.00
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · derivative · entry 9

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,594

Underlying: Common Stock · 1,719 shares

Expires 2026-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/12/2016.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 1,289 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · derivative · entry 8

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,602

Underlying: Common Stock · 1,289 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 3,008 $166.05 $499,478.40
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · nonDerivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 1,719 $90.29 $155,208.51
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,642

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 1,289 $91.05 $117,363.45
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,923

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:35 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 10,000 $0.00 Strike: $59.55 $0.00
Disclosure

SEC source: 0001209191-18-005206 · doc4.xml · derivative · entry 6

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2022-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:35 UTC SaleCommon Stock 10,000 $165.00 $1,650,000.00
Disclosure

SEC source: 0001209191-18-005206 · doc4.xml · nonDerivative · entry 4

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,217

F1 · kind: Transaction made pursuant to Ms. MsGlynn's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 23, 2018 Filed Jan 24, 2018 22:35 UTC Exercise / conversionCommon Stock 10,000 $59.55 $595,500.00
Disclosure

SEC source: 0001209191-18-005206 · doc4.xml · nonDerivative · entry 3

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,217

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 23:33 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 5,824 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-005468 · doc4.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,241

Underlying: Common Stock · 5,824 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 23:33 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 5,824 $165.00 $960,960.00
Disclosure

SEC source: 0001209191-18-005468 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,163

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 23:33 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 5,824 $86.52 $503,892.48
Disclosure

SEC source: 0001209191-18-005468 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,987

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 22, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 13,750 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · derivative · entry 12

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 13,750 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: Fully vested.

Read SEC document
January 22, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 13,750 $160.00 $2,200,000.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 7

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,163

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F6 · balance_after: Reflects a change in the form of ownership resulting from transfers of shares between a trust and Mr. Sachdev.

Read SEC document
January 22, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 13,750 $83.36 $1,146,200.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · nonDerivative · entry 6

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,913

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 22, 2018 Filed Jan 24, 2018 22:29 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-005201 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,164

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
January 22, 2018 Filed Jan 24, 2018 22:29 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,796 $160.00 $287,360.00
Disclosure

SEC source: 0001209191-18-005201 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,761

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

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January 22, 2018 Filed Jan 24, 2018 22:29 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-18-005201 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,557

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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January 22, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 2,427 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · derivative · entry 7

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,517

Underlying: Common Stock · 2,427 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

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January 22, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 2,427 $161.52 $392,009.04
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,634

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

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January 22, 2018 Filed Jan 24, 2018 22:33 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 2,427 $86.52 $209,984.04
Disclosure

SEC source: 0001209191-18-005204 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,061

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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January 22, 2018 Filed Jan 24, 2018 22:35 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 10,000 $0.00 Strike: $59.55 $0.00
Disclosure

SEC source: 0001209191-18-005206 · doc4.xml · derivative · entry 5

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2022-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

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January 22, 2018 Filed Jan 24, 2018 22:35 UTC SaleCommon Stock 10,000 $160.00 $1,600,000.00
Disclosure

SEC source: 0001209191-18-005206 · doc4.xml · nonDerivative · entry 2

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,217

F1 · kind: Transaction made pursuant to Ms. MsGlynn's company-approved trading plan under Rule 10b5-1.

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January 22, 2018 Filed Jan 24, 2018 22:35 UTC Exercise / conversionCommon Stock 10,000 $59.55 $595,500.00
Disclosure

SEC source: 0001209191-18-005206 · doc4.xml · nonDerivative · entry 1

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,217

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 13,750 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · derivative · entry 11

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,750

Underlying: Common Stock · 13,750 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: Fully vested.

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January 19, 2018 Filed Jan 23, 2018 21:56 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 18,672 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-18-004928 · doc4.xml · derivative · entry 10

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,578

Underlying: Common Stock · 18,672 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/5/2014.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.