Tapewire

Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 26, 2018 Filed Feb 28, 2018 14:22 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 6,459 $169.00 $1,091,571.00
Disclosure

SEC source: 0001209191-18-014340 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,752

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 26, 2018 Filed Feb 28, 2018 14:22 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 1,554 $86.52 $134,452.08
Disclosure

SEC source: 0001209191-18-014340 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,211

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 26, 2018 Filed Feb 28, 2018 14:30 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,155 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-014341 · doc4.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,242

Underlying: Common Stock · 2,155 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
February 26, 2018 Filed Feb 28, 2018 14:30 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 2,155 $170.00 $366,350.00
Disclosure

SEC source: 0001209191-18-014341 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,662

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 26, 2018 Filed Feb 28, 2018 14:30 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 2,155 $91.05 $196,212.75
Disclosure

SEC source: 0001209191-18-014341 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,817

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 20, 2018 Filed Feb 21, 2018 23:16 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 3,437 $158.49 $544,730.13
Disclosure

SEC source: 0001209191-18-012084 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,525

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 13, 2018 Filed Feb 15, 2018 21:23 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 2,022 $152.26 $307,869.72
Disclosure

SEC source: 0001209191-18-010396 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,657

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

Read SEC document
February 13, 2018 Filed Feb 15, 2018 21:23 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 2,022 $151.40 $306,130.80
Disclosure

SEC source: 0001209191-18-010396 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,679

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:23 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 4,213 $153.41 $646,316.33
Disclosure

SEC source: 0001209191-18-010005 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,962

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:39 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 12,136 $153.41 $1,861,783.76
Disclosure

SEC source: 0001209191-18-010038 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,998

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:53 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 100 $153.84 $15,384.00
Disclosure

SEC source: 0001209191-18-010068 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,999

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:53 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 700 $153.11 $107,177.00
Disclosure

SEC source: 0001209191-18-010068 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,099

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $153.11 (range $152.71 to $153.59).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:53 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,953 $151.40 $295,684.20
Disclosure

SEC source: 0001209191-18-010068 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,799

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $151.40 (range $151.02 to $151.90).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:53 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,900 $150.67 $286,273.00
Disclosure

SEC source: 0001209191-18-010068 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,752

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $150.67 (range $150.01 to $150.97).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 22:53 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,750 $149.23 $261,152.50
Disclosure

SEC source: 0001209191-18-010068 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,652

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $149.23 (range $148.77 to $149.74).

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 300 $153.69 $46,107.00
Disclosure

SEC source: 0001209191-18-010119 · doc4.xml · nonDerivative · entry 5

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,663

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $153.69 (range $153.59 to $153.90).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 400 $152.62 $61,048.00
Disclosure

SEC source: 0001209191-18-010119 · doc4.xml · nonDerivative · entry 4

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,963

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $152.62 (range $152.09 to $152.96).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 2,022 $151.26 $305,847.72
Disclosure

SEC source: 0001209191-18-010119 · doc4.xml · nonDerivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,363

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $151.26 (range $150.88 to $151.86).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,100 $150.47 $165,517.00
Disclosure

SEC source: 0001209191-18-010119 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,385

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $150.47 (range $149.83 to $150.76).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:15 UTC
Chodakewitz JeffreyEVP GMDA, CMO
SaleCommon Stock 1,300 $149.21 $193,973.00
Disclosure

SEC source: 0001209191-18-010119 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,485

F1 · kind: Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $149.21 (range $148.80 to $149.64).

F3 · price: Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:06 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 200 $153.89 $30,778.00
Disclosure

SEC source: 0001209191-18-010105 · doc4.xml · nonDerivative · entry 6

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 190,658

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $153.89 (range $153.88 to $153.89).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:06 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 2,000 $153.29 $306,580.00
Disclosure

SEC source: 0001209191-18-010105 · doc4.xml · nonDerivative · entry 5

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 190,858

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $153.29 (range $152.88 to $153.84).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:06 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 1,200 $152.40 $182,880.00
Disclosure

SEC source: 0001209191-18-010105 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 192,858

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $152.40 (range $151.85 to $152.81).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:06 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 10,100 $151.23 $1,527,423.00
Disclosure

SEC source: 0001209191-18-010105 · doc4.xml · nonDerivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 194,058

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $151.23 (range $150.83 to $151.82).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:06 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 4,305 $150.44 $647,644.20
Disclosure

SEC source: 0001209191-18-010105 · doc4.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 204,158

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $150.44 (range $149.79 to $150.76).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:06 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 6,100 $149.22 $910,242.00
Disclosure

SEC source: 0001209191-18-010105 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 208,463

F1 · kind: Transaction made pursuant to Dr. Leiden's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $149.22 (range $148.77 to $149.74).

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 1,270 $153.80 $195,326.00
Disclosure

SEC source: 0001209191-18-010129 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,701

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $153.80 (range $153.67 to $153.99).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 3,879 $153.07 $593,758.53
Disclosure

SEC source: 0001209191-18-010129 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,971

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $153.07 (range $152.67 to $153.66).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 800 $152.27 $121,816.00
Disclosure

SEC source: 0001209191-18-010129 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,850

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $152.27 (range $151.67 to $152.62).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:16 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 875 $150.78 $131,932.50
Disclosure

SEC source: 0001209191-18-010129 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,650

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $150.78 (range $150.42 to $151.20).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 300 $153.92 $46,176.00
Disclosure

SEC source: 0001209191-18-010146 · doc4.xml · nonDerivative · entry 6

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,662

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $153.92 (range $153.89 to $153.99).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 1,400 $153.25 $214,550.00
Disclosure

SEC source: 0001209191-18-010146 · doc4.xml · nonDerivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,962

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $153.25 (range $152.87 to $153.82).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 1,100 $152.26 $167,486.00
Disclosure

SEC source: 0001209191-18-010146 · doc4.xml · nonDerivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,362

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $152.26 (range $151.83 to $152.81).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 7,296 $151.22 $1,103,301.12
Disclosure

SEC source: 0001209191-18-010146 · doc4.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,462

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $151.22 (range $150.81 to $151.79).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 3,200 $150.44 $481,408.00
Disclosure

SEC source: 0001209191-18-010146 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,758

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $150.44 (range $149.81 to $150.76).

Read SEC document
February 12, 2018 Filed Feb 14, 2018 23:23 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 4,500 $149.22 $671,490.00
Disclosure

SEC source: 0001209191-18-010146 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,958

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $149.22 (range $148.77 to $149.75).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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February 06, 2018 Filed Feb 8, 2018 22:49 UTC
Chodakewitz JeffreyEVP GMDA, CMO
GrantStock Option (Right to Buy) · Derivative 23,479 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-18-008515 · doc4.xml · derivative · entry 3

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,479

Underlying: Common Stock · 23,479 shares

Expires 2028-02-05

F3 · derivative.exercise_date: This option vests in 16 quarterly installments from 2/6/2018.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:49 UTC
Chodakewitz JeffreyEVP GMDA, CMO
GrantCommon Stock 10,125 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008515 · doc4.xml · nonDerivative · entry 2

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,785

F2 · shares: Restricted stock unit award that vests in three equal installments on 2/17/2019, 2/17/2020 and 2/17/2021.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:49 UTC
Chodakewitz JeffreyEVP GMDA, CMO
GrantCommon Stock 12,136 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008515 · doc4.xml · nonDerivative · entry 1

Chodakewitz Jeffrey · CIK 0001610876 · EVP GMDA, CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,660

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 2/3/2017 that contained both performance-vesting and service-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 2/6/2018. The earned performance shares remain subject to the service-vesting requirements and will vest in three equal installments on 2/10/2018, 2/10/2019 and 2/10/2020.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:53 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
GrantStock Option (Right to Buy) · Derivative 19,566 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-18-008518 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,566

Underlying: Common Stock · 19,566 shares

Expires 2028-02-05

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2018.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:53 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
GrantCommon Stock 8,437 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008518 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,525

F2 · shares: Restricted stock unit award that vests in three equal installments on 2/17/2019, 2/17/2020 and 2/17/2021.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:53 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
GrantCommon Stock 12,136 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008518 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,088

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 2/3/2017 that contained both performance-vesting and service-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 2/6/2018. The earned performance shares remain subject to the service-vesting requirements and will vest in three equal installments on 2/10/2018, 2/10/2019 and 2/10/2020.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:58 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
GrantStock Option (Right to Buy) · Derivative 19,566 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-18-008519 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,566

Underlying: Common Stock · 19,566 shares

Expires 2028-02-05

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2018.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:58 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
GrantCommon Stock 8,437 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008519 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,402

F2 · shares: Restricted stock unit award that vests in three equal installments on 2/17/2019, 2/17/2020 and 2/17/2021.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 22:58 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
GrantCommon Stock 18,204 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008519 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,965

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 2/03/2017 that contained both performance-vesting and service-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 2/6/2018. The earned performance shares remain subject to the service-vesting requirements and will vest in three equal installments on 2/10/2018, 2/10/2019 and 2/10/2020.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 23:07 UTC
LEIDEN JEFFREY MDirector · CEO & President
GrantStock Option (Right to Buy) · Derivative 73,046 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-18-008526 · doc4.xml · derivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,046

Underlying: Common Stock · 73,046 shares

Expires 2028-02-05

F3 · derivative.exercise_date: This option vests in 16 quarterly installments from 2/6/2018.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 23:07 UTC
LEIDEN JEFFREY MDirector · CEO & President
GrantCommon Stock 31,498 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008526 · doc4.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 214,563

F2 · shares: Restricted stock unit award that vests in three equal installments on 2/17/2019, 2/17/2020 and 2/17/2021.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 23:07 UTC
LEIDEN JEFFREY MDirector · CEO & President
GrantCommon Stock 50,568 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008526 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,065

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 2/03/2017 that contained both performance-vesting and service-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/06/2018. The earned performance shares remain subject to the service-vesting requirements and will vest in three equal installments on 2/10/2018, 2/10/2019 and 2/10/2020.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 23:10 UTC
Sachdev AmitEVP, CRO
GrantStock Option (Right to Buy) · Derivative 23,479 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-18-008531 · doc4.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,479

Underlying: Common Stock · 23,479 shares

Expires 2028-02-05

F3 · derivative.exercise_date: This option vests in 16 quarterly installments from 2/6/2018.

Read SEC document
February 06, 2018 Filed Feb 8, 2018 23:10 UTC
Sachdev AmitEVP, CRO
GrantCommon Stock 10,125 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-008531 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,458

F2 · shares: Restricted stock unit award that vests in three equal installments on 2/17/2019, 2/17/2020 and 2/17/2021.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.