Tapewire

Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

Export transactions ↓
Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 15, 2018 Filed May 16, 2018 20:48 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 98 $155.78 $15,266.44
Disclosure

SEC source: 0001209191-18-030546 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,999

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2018 Filed May 16, 2018 21:06 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 83 $155.78 $12,929.74
Disclosure

SEC source: 0001209191-18-030587 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,662

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2018 Filed May 16, 2018 21:11 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 138 $155.78 $21,497.64
Disclosure

SEC source: 0001209191-18-030593 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,752

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2018 Filed May 16, 2018 21:21 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 217 $155.78 $33,804.26
Disclosure

SEC source: 0001209191-18-030604 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,699

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2018 Filed May 16, 2018 21:24 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 85 $155.78 $13,241.30
Disclosure

SEC source: 0001209191-18-030610 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,609

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2018 Filed May 16, 2018 21:27 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 201 $155.78 $31,311.78
Disclosure

SEC source: 0001209191-18-030616 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,087

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 11, 2018 Filed May 15, 2018 20:21 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,941 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-030207 · doc4.xml · derivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,358

Underlying: Common Stock · 1,941 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
May 11, 2018 Filed May 15, 2018 20:21 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,155 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-030207 · doc4.xml · derivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,086

Underlying: Common Stock · 2,155 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
May 11, 2018 Filed May 15, 2018 20:21 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 4,096 $155.00 $634,880.00
Disclosure

SEC source: 0001209191-18-030207 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,699

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 11, 2018 Filed May 15, 2018 20:21 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 1,941 $86.52 $167,935.32
Disclosure

SEC source: 0001209191-18-030207 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,795

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 11, 2018 Filed May 15, 2018 20:21 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 2,155 $91.05 $196,212.75
Disclosure

SEC source: 0001209191-18-030207 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,854

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 03, 2018 Filed May 4, 2018 20:23 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-028114 · doc4.xml · derivative · entry 3

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,629

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
May 03, 2018 Filed May 4, 2018 20:23 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 2,330 $149.50 $348,335.00
Disclosure

SEC source: 0001209191-18-028114 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,609

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 03, 2018 Filed May 4, 2018 20:23 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-18-028114 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,939

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy · Derivative 51,000 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · derivative · entry 15

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

Underlying: Common Stock · 51,000 shares

Expires 2025-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2015.

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy · Derivative 2,125 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · derivative · entry 14

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,125

Underlying: Common Stock · 2,125 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/15/2014.

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 53,125 $160.12 $8,506,375.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 9

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,699

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $160.12 (range $160.00 to $160.23).

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 51,000 $109.14 $5,566,140.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 8

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,824

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 2,125 $96.87 $205,848.75
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 7

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,824

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:38 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 38,250 $159.56 $6,103,170.00
Disclosure

SEC source: 0001209191-18-026609 · doc4.xml · nonDerivative · entry 5

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,609

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $159.56 (range $159.51 to $159.60).

Read SEC document
April 26, 2018 Filed Apr 27, 2018 20:38 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionCommon Stock 38,250 $122.45 $4,683,712.50
Disclosure

SEC source: 0001209191-18-026609 · doc4.xml · nonDerivative · entry 4

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,859

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy · Derivative 7,766 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · derivative · entry 13

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,299

Underlying: Common Stock · 7,766 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2017.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy · Derivative 2,156 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · derivative · entry 12

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,241

Underlying: Common Stock · 2,156 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/02/2016.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionStock Option (Right to Buy · Derivative 4,250 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · derivative · entry 11

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,250 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: Fully vested.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 2,700 $156.78 $423,306.00
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,699

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $156.78 (range $156.38 to $157.29).

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 9,790 $155.62 $1,523,519.80
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,399

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $155.62 (range $155.32 to $156.29).

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
SaleCommon Stock 19,478 $154.98 $3,018,700.44
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,189

F1 · kind: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $154.98 (range $154.32 to $155.31).

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 7,766 $86.52 $671,914.32
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,667

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 2,156 $91.05 $196,303.80
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,901

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:37 UTC
SMITH IAN FEVP, COO
Exercise / conversionCommon Stock 4,250 $77.31 $328,567.50
Disclosure

SEC source: 0001209191-18-026607 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,745

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:38 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $90.29 $0.00
Disclosure

SEC source: 0001209191-18-026609 · doc4.xml · derivative · entry 6

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,125

Underlying: Common Stock · 2,125 shares

Expires 2026-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/12/2016.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:38 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 300 $156.36 $46,908.00
Disclosure

SEC source: 0001209191-18-026609 · doc4.xml · nonDerivative · entry 3

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,609

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $156.36 (range $155.97 to $156.75).

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:38 UTC
Parini MichaelEVP, CL&AO
SaleCommon Stock 2,214 $155.07 $343,324.98
Disclosure

SEC source: 0001209191-18-026609 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,909

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $155.07 (range $154.61 to $155.56).

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 25, 2018 Filed Apr 27, 2018 20:38 UTC
Parini MichaelEVP, CL&AO
Exercise / conversionCommon Stock 2,125 $90.29 $191,866.25
Disclosure

SEC source: 0001209191-18-026609 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, CL&AO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,123

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 18, 2018 Filed Apr 19, 2018 21:37 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 859 $0.00 Strike: $90.29 $0.00
Disclosure

SEC source: 0001209191-18-025619 · doc4.xml · derivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,735

Underlying: Common Stock · 859 shares

Expires 2026-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/12/2016.

Read SEC document
April 18, 2018 Filed Apr 19, 2018 21:37 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 859 $166.05 $142,636.95
Disclosure

SEC source: 0001209191-18-025619 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,087

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
April 18, 2018 Filed Apr 19, 2018 21:37 UTC
Silva Paul MSVP & Corp Controller
Exercise / conversionCommon Stock 859 $90.29 $77,559.11
Disclosure

SEC source: 0001209191-18-025619 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,946

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 16, 2018 Filed Apr 18, 2018 18:50 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-025334 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,125

Underlying: Common Stock · 2,125 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/15/2014.

Read SEC document
April 16, 2018 Filed Apr 18, 2018 18:50 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
SaleCommon Stock 2,125 $163.01 $346,396.25
Disclosure

SEC source: 0001209191-18-025334 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,752

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company-approved trading plan under Rule 10b5-1.

Read SEC document
April 16, 2018 Filed Apr 18, 2018 18:50 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionCommon Stock 2,125 $96.87 $205,848.75
Disclosure

SEC source: 0001209191-18-025334 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,877

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 16, 2018 Filed Apr 18, 2018 18:51 UTC GrantDeferred Stock Units · Derivative 279.695 $160.89 $45,000.13
Disclosure

SEC source: 0001209191-18-025337 · doc4.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,399.164

Underlying: Common Stock · 279.695 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

Read SEC document
April 02, 2018 Filed Apr 4, 2018 21:07 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 138 $161.99 $22,354.62
Disclosure

SEC source: 0001209191-18-023770 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,087

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

Read SEC document
April 02, 2018 Filed Apr 4, 2018 21:07 UTC
Silva Paul MSVP & Corp Controller
SaleCommon Stock 3,300 $161.18 $531,894.00
Disclosure

SEC source: 0001209191-18-023770 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,225

F1 · kind: Transaction made pursuant to Mr. Silva's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $161.18 (range $160.64 to $161.52).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 09, 2018 Filed Mar 12, 2018 21:36 UTC
Sachdev AmitEVP, CRO
Exercise / conversionStock Option (Right to Buy) · Derivative 13,750 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-18-018919 · doc4.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,750

Underlying: Common Stock · 13,750 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/15/2014.

Read SEC document
March 09, 2018 Filed Mar 12, 2018 21:36 UTC
Sachdev AmitEVP, CRO
SaleCommon Stock 13,750 $175.00 $2,406,250.00
Disclosure

SEC source: 0001209191-18-018919 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,662

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

Read SEC document
March 09, 2018 Filed Mar 12, 2018 21:36 UTC
Sachdev AmitEVP, CRO
Exercise / conversionCommon Stock 13,750 $96.87 $1,331,962.50
Disclosure

SEC source: 0001209191-18-018919 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,412

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 02, 2018 Filed Mar 5, 2018 23:13 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 10,000 $0.00 Strike: $81.54 $0.00
Disclosure

SEC source: 0001209191-18-016827 · doc4.xml · derivative · entry 3

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
March 02, 2018 Filed Mar 5, 2018 23:13 UTC SaleCommon Stock 10,000 $170.00 $1,700,000.00
Disclosure

SEC source: 0001209191-18-016827 · doc4.xml · nonDerivative · entry 2

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,312

F1 · kind: Transaction made pursuant to Ms. McGlynn's company approved trading plan under Rule 10b5-1.

Read SEC document
March 02, 2018 Filed Mar 5, 2018 23:13 UTC Exercise / conversionCommon Stock 10,000 $81.54 $815,400.00
Disclosure

SEC source: 0001209191-18-016827 · doc4.xml · nonDerivative · entry 1

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,312

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 26, 2018 Filed Feb 28, 2018 14:22 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 1,554 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-014340 · doc4.xml · derivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,639

Underlying: Common Stock · 1,554 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.