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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
April 12, 2022 Filed Apr 14, 2022 20:35 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $0.00 Strike: $81.54 $0.00
Disclosure

SEC source: 0000899243-22-014804 · doc4.xml · derivative · entry 15

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F14 · derivative.exercise_date: Fully vested.

Read SEC document
April 12, 2022 Filed Apr 14, 2022 20:35 UTC
Lee YuchunDirector
SaleCommon Stock 300 $283.15 $84,945.00
Disclosure

SEC source: 0000899243-22-014804 · doc4.xml · nonDerivative · entry 5

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $283.15 (range $282.73 to $283.57).

Read SEC document
April 12, 2022 Filed Apr 14, 2022 20:35 UTC
Lee YuchunDirector
SaleCommon Stock 318 $281.70 $89,580.60
Disclosure

SEC source: 0000899243-22-014804 · doc4.xml · nonDerivative · entry 4

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,175

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $281.70 (range $281.45 to $281.98).

Read SEC document
April 12, 2022 Filed Apr 14, 2022 20:35 UTC
Lee YuchunDirector
SaleCommon Stock 1,182 $280.61 $331,681.02
Disclosure

SEC source: 0000899243-22-014804 · doc4.xml · nonDerivative · entry 3

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,493

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $280.61 (range $280.24 to $281.19).

Read SEC document
April 12, 2022 Filed Apr 14, 2022 20:35 UTC
Lee YuchunDirector
SaleCommon Stock 200 $279.22 $55,844.00
Disclosure

SEC source: 0000899243-22-014804 · doc4.xml · nonDerivative · entry 2

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,675

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $279.22 (range $279.14 to $279.30).

Read SEC document
April 12, 2022 Filed Apr 14, 2022 20:35 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,000 $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014804 · doc4.xml · nonDerivative · entry 1

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 11, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $0.00 Strike: $81.54 $0.00
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · derivative · entry 11

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: Fully vested.

Read SEC document
April 11, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 110 $281.58 $30,973.80
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 9

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $281.58 (range $281.55 to $281.58).

Read SEC document
April 11, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 968 $280.62 $271,640.16
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 8

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,985

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $280.62 (range $280.31 to $281.28).

Read SEC document
April 11, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 922 $279.81 $257,984.82
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 7

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,953

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $279.81 (range $279.29 to $280.18).

Read SEC document
April 11, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,000 $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 6

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $127.54 $0.00
Disclosure

SEC source: 0000899243-22-014548 · doc4.xml · derivative · entry 4

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2025-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC SaleCommon Stock 100 $281.49 $28,149.00
Disclosure

SEC source: 0000899243-22-014548 · doc4.xml · nonDerivative · entry 3

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,099

F1 · kind: Transaction made pursuant to Ms. McGlynn's company approved trading plan under Rule 10b5-1.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC SaleCommon Stock 4,900 $280.19 $1,372,931.00
Disclosure

SEC source: 0000899243-22-014548 · doc4.xml · nonDerivative · entry 2

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,199

F1 · kind: Transaction made pursuant to Ms. McGlynn's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. McGlynn undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $280.19 (range $280.00 to $280.95).

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC Exercise / conversionCommon Stock 5,000 $127.54 $637,700.00
Disclosure

SEC source: 0000899243-22-014548 · doc4.xml · nonDerivative · entry 1

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,099

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 1,907 $0.00 Strike: $125.71 $0.00
Disclosure

SEC source: 0000899243-22-014549 · doc4.xml · derivative · entry 3

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,907 shares

Expires 2027-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC SaleCommon Stock 1,907 $280.20 $534,341.40
Disclosure

SEC source: 0000899243-22-014549 · doc4.xml · nonDerivative · entry 2

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,191

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $280.20 (range $280.00 to $280.53).

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:05 UTC Exercise / conversionCommon Stock 1,907 $125.71 $239,728.97
Disclosure

SEC source: 0000899243-22-014549 · doc4.xml · nonDerivative · entry 1

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,098

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $0.00 Strike: $81.54 $0.00
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · derivative · entry 10

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: Fully vested.

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 452 $280.37 $126,727.24
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 5

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $280.37 (range $280.06 to $281.02).

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 700 $279.36 $195,552.00
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 4

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,327

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $279.36 (range $278.86 to $279.74).

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 430 $277.29 $119,234.70
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 3

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,027

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $277.29 (range $277.16 to $277.46).

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
SaleCommon Stock 418 $276.62 $115,627.16
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 2

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,457

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $276.62 (range $276.08 to $276.81).

Read SEC document
April 08, 2022 Filed Apr 12, 2022 20:07 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,000 $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014551 · doc4.xml · nonDerivative · entry 1

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 07, 2022 Filed Apr 8, 2022 20:34 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 30 $277.02 $8,310.60
Disclosure

SEC source: 0000899243-22-014360 · doc4.xml · nonDerivative · entry 3

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,782

F1 · kind: Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.

Read SEC document
April 07, 2022 Filed Apr 8, 2022 20:34 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 327 $276.39 $90,379.53
Disclosure

SEC source: 0000899243-22-014360 · doc4.xml · nonDerivative · entry 2

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,812

F1 · kind: Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Sanna undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $276.39 (range $276.00 to $276.78).

Read SEC document
April 07, 2022 Filed Apr 8, 2022 20:34 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 204 $275.71 $56,244.84
Disclosure

SEC source: 0000899243-22-014360 · doc4.xml · nonDerivative · entry 1

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,139

F1 · kind: Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Sanna undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $275.71 (range $275.00 to $275.95).

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $0.00 Strike: $81.54 $0.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · derivative · entry 13

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 100 $277.02 $27,702.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 11

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 727 $276.37 $200,920.99
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 10

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,975

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F10 · price: Open market sales reported on this line occurred at a weighted average price of $276.37 (range $275.94 to $276.82).

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 256 $275.26 $70,466.56
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 9

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,702

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $275.26 (range $274.64 to $275.43).

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 500 $273.78 $136,890.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 8

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,958

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $273.78 (range $273.52 to $273.98).

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 417 $272.76 $113,740.92
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 7

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,458

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $272.76 (range $272.50 to $273.28).

Read SEC document
April 07, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,000 $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 6

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 06, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $0.00 Strike: $81.54 $0.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · derivative · entry 12

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
April 06, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 83 $272.84 $22,645.72
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 5

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $272.84 (range $272.56 to $272.97).

Read SEC document
April 06, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 1,600 $271.78 $434,848.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 4

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,958

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $271.78 (range $271.43 to $272.33).

Read SEC document
April 06, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 300 $270.67 $81,201.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 3

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,558

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $270.67 (range $270.42 to $270.88).

Read SEC document
April 06, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
SaleCommon Stock 17 $267.57 $4,548.69
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 2

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,858

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

Read SEC document
April 06, 2022 Filed Apr 8, 2022 21:57 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,000 $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014367 · doc4.xml · nonDerivative · entry 1

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $81.54 Strike: $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · derivative · entry 13

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
SaleCommon Stock 461 $274.66 $126,618.26
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 11

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $274.66 (range $274.63 to $274.68).

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
SaleCommon Stock 100 $273.50 $27,350.00
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 10

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,336

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
SaleCommon Stock 600 $272.60 $163,560.00
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 9

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,436

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $272.60 (range $272.36 to $273.34).

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
SaleCommon Stock 488 $271.94 $132,706.72
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 8

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,036

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $271.94 (range $271.35 to $272.27).

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
SaleCommon Stock 334 $270.05 $90,196.70
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 7

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,524

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $270.05 (range $269.79 to $270.64).

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
SaleCommon Stock 17 $268.30 $4,561.10
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 6

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,858

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

Read SEC document
April 05, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,000 $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · nonDerivative · entry 5

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 05, 2022 Filed Apr 6, 2022 21:02 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 3,163 $275.23 $870,552.49
Disclosure

SEC source: 0000899243-22-014120 · doc4.xml · nonDerivative · entry 3

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,343

F1 · kind: Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Sanna undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $275.23 (range $275.00 to $275.66).

Read SEC document
April 04, 2022 Filed Apr 6, 2022 20:59 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $81.54 Strike: $81.54 $163,080.00
Disclosure

SEC source: 0000899243-22-014117 · doc4.xml · derivative · entry 12

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 2,000 shares

Expires 2023-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.