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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 24, 2023 Filed Jan 25, 2023 21:08 UTC
Lee YuchunDirector
SaleCommon Stock 2,511 $312.29 $784,160.19
Disclosure

SEC source: 0001209191-23-004816 · doc4.xml · nonDerivative · entry 4

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,364

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $312.29 (range $312.00 to $312.92).

Read SEC document
January 24, 2023 Filed Jan 25, 2023 21:08 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 4,000 $72.14 $288,560.00
Disclosure

SEC source: 0001209191-23-004816 · doc4.xml · nonDerivative · entry 3

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2023 Filed Jan 25, 2023 21:08 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,129 $0.00 Strike: $72.14 $0.00
Disclosure

SEC source: 0001209191-23-004816 · doc4.xml · derivative · entry 6

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,429

Underlying: Common Stock · 2,129 shares

Expires 2024-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
January 23, 2023 Filed Jan 25, 2023 21:08 UTC
Lee YuchunDirector
SaleCommon Stock 2,129 $312.02 $664,290.58
Disclosure

SEC source: 0001209191-23-004816 · doc4.xml · nonDerivative · entry 2

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $312.02 (range $312.00 to $312.17).

Read SEC document
January 23, 2023 Filed Jan 25, 2023 21:08 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 2,129 $72.14 $153,586.06
Disclosure

SEC source: 0001209191-23-004816 · doc4.xml · nonDerivative · entry 1

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,004

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 18, 2023 Filed Jan 19, 2023 21:07 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 442 $0.00 Strike: $72.14 $0.00
Disclosure

SEC source: 0001209191-23-004005 · doc4.xml · derivative · entry 6

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,558

Underlying: Common Stock · 442 shares

Expires 2024-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
January 18, 2023 Filed Jan 19, 2023 21:07 UTC
Lee YuchunDirector
SaleCommon Stock 442 $312.17 $137,979.14
Disclosure

SEC source: 0001209191-23-004005 · doc4.xml · nonDerivative · entry 4

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $312.17 (range $312.00 to $312.53).

Read SEC document
January 18, 2023 Filed Jan 19, 2023 21:07 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 442 $72.14 $31,885.88
Disclosure

SEC source: 0001209191-23-004005 · doc4.xml · nonDerivative · entry 3

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,317

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 17, 2023 Filed Jan 19, 2023 21:07 UTC
Lee YuchunDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 4,000 $0.00 Strike: $72.14 $0.00
Disclosure

SEC source: 0001209191-23-004005 · doc4.xml · derivative · entry 5

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 4,000 shares

Expires 2024-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
January 17, 2023 Filed Jan 19, 2023 21:07 UTC
Lee YuchunDirector
SaleCommon Stock 4,000 $312.03 $1,248,120.00
Disclosure

SEC source: 0001209191-23-004005 · doc4.xml · nonDerivative · entry 2

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,875

F1 · kind: Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $312.03 (range $312.00 to $312.14).

Read SEC document
January 17, 2023 Filed Jan 19, 2023 21:07 UTC
Lee YuchunDirector
Exercise / conversionCommon Stock 4,000 $72.14 $288,560.00
Disclosure

SEC source: 0001209191-23-004005 · doc4.xml · nonDerivative · entry 1

Lee Yuchun · CIK 0001334365 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 13, 2023 Filed Jan 18, 2023 21:07 UTC GrantDeferred Stock Units · Derivative 100.53 $298.42 $30,000.16
Disclosure

SEC source: 0001209191-23-003703 · doc4.xml · derivative · entry 1

MCKENZIE DIANA · CIK 0001754648 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,027.368

Underlying: Common Stock · 100.53 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

Read SEC document
January 13, 2023 Filed Jan 18, 2023 21:15 UTC GrantDeferred Stock Units · Derivative 146.606 $298.42 $43,750.16
Disclosure

SEC source: 0001209191-23-003726 · doc4.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,268.774

Underlying: Common Stock · 146.606 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

Read SEC document
January 13, 2023 Filed Jan 18, 2023 21:23 UTC GrantDeferred Stock Units · Derivative 96.341 $298.42 $28,750.08
Disclosure

SEC source: 0001209191-23-003744 · doc4.xml · derivative · entry 1

Upadhyay Suketu · CIK 0001533149 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 234.996

Underlying: Common Stock · 96.341 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Upadhyay's service on our board of directors, (ii) a change of control of our company and (iii) Mr. Upadhyay's disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Upadhyay's service on our board of directors, (ii) a change of control of our company and (iii) Mr. Upadhyay's disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Upadhyay's service on our board of directors, (ii) a change of control of our company and (iii) Mr. Upadhyay's disability or death.

Read SEC document
December 06, 2022 Filed Dec 8, 2022 21:08 UTC GrantCommon Stock 12,753 $0.00 $0.00
Disclosure

SEC source: 0001209191-22-060339 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,031

F1 · shares: Restricted stock unit award that vests on 07/01/2025.

Read SEC document
November 15, 2022 Filed Nov 17, 2022 21:08 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 34 $308.61 $10,492.74
Disclosure

SEC source: 0000899243-22-036184 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,303 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · derivative · entry 9

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,304

Underlying: Common Stock · 1,303 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2019.

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 83 $306.57 $25,445.31
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 8

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $306.57 (range $306.45 to $307.22).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 140 $305.39 $42,754.60
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 7

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,160

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $305.39 (range $305.38 to $305.39).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 280 $304.58 $85,282.40
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,300

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $304.58 (range $304.14 to $304.91).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 261 $303.21 $79,137.81
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,580

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $303.21 (range $302.89 to $303.45).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 189 $301.99 $57,076.11
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,841

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $301.99 (range $301.84 to $302.20).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 210 $300.96 $63,201.60
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,030

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $300.96 (range $300.54 to $301.18).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 140 $299.72 $41,960.80
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,240

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $299.72 (range $299.46 to $299.97).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionCommon Stock 1,303 $187.53 $244,351.59
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,380

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 22 $317.77 $6,990.94
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 8

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,104

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $317.77 (range $317.56 to $317.82).

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 10 $315.68 $3,156.80
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 7

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,126

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 12 $314.43 $3,773.16
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 6

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,136

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $314.43 (range $314.42 to $314.48).

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 81 $313.37 $25,382.97
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 5

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,148

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $313.37 (range $312.98 to $313.97).

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 100 $312.40 $31,240.00
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 4

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,229

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $312.40 (range $311.98 to $312.90).

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 39 $311.17 $12,135.63
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 3

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,329

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $311.17 (range $310.51 to $311.45).

Read SEC document
November 02, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 56 $310.10 $17,365.60
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 2

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,368

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $310.10 (range $309.50 to $310.48).

Read SEC document
November 01, 2022 Filed Nov 3, 2022 20:05 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
Tax withholdingCommon Stock 768 $312.84 $240,261.12
Disclosure

SEC source: 0000899243-22-034883 · doc4.xml · nonDerivative · entry 1

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,424

Read SEC document
October 24, 2022 Filed Oct 26, 2022 20:05 UTC SaleCommon Stock 621 $310.00 $192,510.00
Disclosure

SEC source: 0000899243-22-034249 · doc4.xml · nonDerivative · entry 1

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,040

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

Read SEC document
October 18, 2022 Filed Oct 20, 2022 20:11 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 288 $301.84 $86,929.92
Disclosure

SEC source: 0000899243-22-033880 · doc4.xml · nonDerivative · entry 2

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,192

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $301.84 (range $301.14 to $301.98).

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October 18, 2022 Filed Oct 20, 2022 20:11 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 1,503 $300.02 $450,930.06
Disclosure

SEC source: 0000899243-22-033880 · doc4.xml · nonDerivative · entry 1

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,480

F1 · kind: Transaction made pursuant to Dr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Sanna undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $300.02 (range $300.00 to $300.14).

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October 14, 2022 Filed Oct 18, 2022 20:25 UTC GrantDeferred Stock Units · Derivative 101.072 $296.82 $30,000.19
Disclosure

SEC source: 0000899243-22-033743 · doc4.xml · derivative · entry 1

MCKENZIE DIANA · CIK 0001754648 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,926.838

Underlying: Common Stock · 101.072 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

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October 14, 2022 Filed Oct 18, 2022 20:27 UTC GrantDeferred Stock Units · Derivative 147.396 $296.82 $43,750.08
Disclosure

SEC source: 0000899243-22-033744 · doc4.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,122.168

Underlying: Common Stock · 147.396 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

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October 14, 2022 Filed Oct 18, 2022 20:30 UTC GrantDeferred Stock Units · Derivative 96.861 $296.82 $28,750.28
Disclosure

SEC source: 0000899243-22-033745 · doc4.xml · derivative · entry 1

Upadhyay Suketu · CIK 0001533149 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 138.655

Underlying: Common Stock · 96.861 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Upadhyay's service on our board of directors, (ii) a change of control of our company and (iii) Mr. Upadhyay's disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Upadhyay's service on our board of directors, (ii) a change of control of our company and (iii) Mr. Upadhyay's disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Upadhyay's service on our board of directors, (ii) a change of control of our company and (iii) Mr. Upadhyay's disability or death.

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September 19, 2022 Filed Sep 21, 2022 20:10 UTC
Biller JonathanEVP and Chief Legal Officer
GrantCommon Stock 5,294 $0.00 $0.00
Disclosure

SEC source: 0000899243-22-031641 · doc4.xml · nonDerivative · entry 1

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,294

F1 · shares: Restricted stock unit award that vests in installments beginning on 10/01/2022.

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:36 UTC
Liu JoySVP, General Counsel
SaleCommon Stock 300 $305.57 $91,671.00
Disclosure

SEC source: 0000899243-22-029023 · doc4.xml · nonDerivative · entry 6

Liu Joy · CIK 0001847529 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,605

F1 · kind: Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $305.57 (range $305.55 to $305.58).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:36 UTC
Liu JoySVP, General Counsel
SaleCommon Stock 1,743 $305.01 $531,632.43
Disclosure

SEC source: 0000899243-22-029023 · doc4.xml · nonDerivative · entry 5

Liu Joy · CIK 0001847529 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,905

F1 · kind: Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $305.01 (range $304.54 to $305.53).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:36 UTC
Liu JoySVP, General Counsel
SaleCommon Stock 700 $303.99 $212,793.00
Disclosure

SEC source: 0000899243-22-029023 · doc4.xml · nonDerivative · entry 4

Liu Joy · CIK 0001847529 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,648

F1 · kind: Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $303.99 (range $303.48 to $304.46).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:36 UTC
Liu JoySVP, General Counsel
SaleCommon Stock 100 $302.35 $30,235.00
Disclosure

SEC source: 0000899243-22-029023 · doc4.xml · nonDerivative · entry 3

Liu Joy · CIK 0001847529 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,348

F1 · kind: Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:36 UTC
Liu JoySVP, General Counsel
SaleCommon Stock 698 $301.63 $210,537.74
Disclosure

SEC source: 0000899243-22-029023 · doc4.xml · nonDerivative · entry 2

Liu Joy · CIK 0001847529 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,448

F1 · kind: Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $301.63 (range $301.23 to $302.01).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:36 UTC
Liu JoySVP, General Counsel
SaleCommon Stock 206 $300.26 $61,853.56
Disclosure

SEC source: 0000899243-22-029023 · doc4.xml · nonDerivative · entry 1

Liu Joy · CIK 0001847529 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,146

F1 · kind: Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $300.26 (range $300.00 to $300.28).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:39 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 6,571 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0000899243-22-029030 · doc4.xml · derivative · entry 9

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,571 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:39 UTC SaleCommon Stock 6,948 $305.38 $2,121,780.24
Disclosure

SEC source: 0000899243-22-029030 · doc4.xml · nonDerivative · entry 7

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,278

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $305.38 (range $305.13 to $305.83).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:39 UTC SaleCommon Stock 6,990 $304.67 $2,129,643.30
Disclosure

SEC source: 0000899243-22-029030 · doc4.xml · nonDerivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,226

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $304.67 (range $304.13 to $305.12).

Read SEC document
August 15, 2022 Filed Aug 17, 2022 21:39 UTC SaleCommon Stock 2,339 $303.78 $710,541.42
Disclosure

SEC source: 0000899243-22-029030 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,216

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $303.78 (range $303.13 to $304.09).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.