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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
December 06, 2006 Filed Dec 7, 2006 17:59 UTC Exercise / conversionStock Option · Derivative 3,000 $0.00 Strike: $13.23 $0.00
Disclosure

SEC source: 0000875320-06-000113 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common Stock · 3,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan. Fully vested.

Read SEC document
December 06, 2006 Filed Dec 7, 2006 17:59 UTC SaleCommon Stock 3,000 $44.71 $134,130.00
Disclosure

SEC source: 0000875320-06-000113 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,000

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan established under Rule 10b5-1.

Read SEC document
December 06, 2006 Filed Dec 7, 2006 17:59 UTC Exercise / conversionComon Stock 3,000 $13.23 $39,690.00
Disclosure

SEC source: 0000875320-06-000113 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 05, 2006 Filed Dec 6, 2006 18:21 UTC
BOGER JOSHUA SDirector · President & CEO
Exercise / conversionStock Option · Derivative 11,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000110 · edgar.xml · derivative · entry 5

BOGER JOSHUA S · CIK 0001197023 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,982,531

Underlying: Common Stock · 11,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan, vesting quarterly over 5 years from 12/12/1996.

Read SEC document
December 05, 2006 Filed Dec 6, 2006 18:21 UTC
BOGER JOSHUA SDirector · President & CEO
SaleCommon Stock 11,000 $44.52 $489,720.00
Disclosure

SEC source: 0000875320-06-000110 · edgar.xml · nonDerivative · entry 2

BOGER JOSHUA S · CIK 0001197023 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,035,403

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

Read SEC document
December 05, 2006 Filed Dec 6, 2006 18:21 UTC
BOGER JOSHUA SDirector · President & CEO
Exercise / conversionCommon Stock 11,000 $15.56 $171,160.00
Disclosure

SEC source: 0000875320-06-000110 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,046,403

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 05, 2006 Filed Dec 6, 2006 18:22 UTC Exercise / conversionStock Option · Derivative 3,000 $0.00 Strike: $13.23 $0.00
Disclosure

SEC source: 0000875320-06-000111 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,000

Underlying: Common Stock · 3,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan. Fully vested.

Read SEC document
December 05, 2006 Filed Dec 6, 2006 18:22 UTC SaleCommon Stock 3,000 $44.51 $133,530.00
Disclosure

SEC source: 0000875320-06-000111 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,000

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan established under Rule 10b5-1.

Read SEC document
December 05, 2006 Filed Dec 6, 2006 18:22 UTC Exercise / conversionComon Stock 3,000 $13.23 $39,690.00
Disclosure

SEC source: 0000875320-06-000111 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:07 UTC Exercise / conversionStock Option · Derivative 3,000 $0.00 Strike: $13.23 $0.00
Disclosure

SEC source: 0000875320-06-000109 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,000

Underlying: Common Stock · 3,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan. Fully vested.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:07 UTC SaleCommon Stock 3,000 $44.28 $132,840.00
Disclosure

SEC source: 0000875320-06-000109 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,000

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan established under Rule 10b5-1.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:07 UTC Exercise / conversionComon Stock 3,000 $13.23 $39,690.00
Disclosure

SEC source: 0000875320-06-000109 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:02 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock · Derivative 178 $0.00 Strike: $9.69 $0.00
Disclosure

SEC source: 0000875320-06-000108 · edgar.xml · derivative · entry 6

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,960

Underlying: Common Stock · 178 shares

Expires 2014-06-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 20 equal quarterly installments from 3/17/2004.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:02 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock · Derivative 72 $0.00 Strike: $9.07 $0.00
Disclosure

SEC source: 0000875320-06-000108 · edgar.xml · derivative · entry 5

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,138

Underlying: Common Stock · 72 shares

Expires 2013-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 20 equal quarterly installments from 12/11/2003.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:02 UTC
POWER JOHANNA MESSINAVP & Controller
SaleCommon Stock 250 $44.28 $11,070.00
Disclosure

SEC source: 0000875320-06-000108 · edgar.xml · nonDerivative · entry 3

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,297

F1 · kind: Transaction made pursuant to Ms. Messina-Power's company approved trading plan established under Rule 10b5-1.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:02 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock 178 $9.69 $1,724.82
Disclosure

SEC source: 0000875320-06-000108 · edgar.xml · nonDerivative · entry 2

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,547

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 04, 2006 Filed Dec 5, 2006 19:02 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock 72 $9.07 $653.04
Disclosure

SEC source: 0000875320-06-000108 · edgar.xml · nonDerivative · entry 1

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,369

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 01, 2006 Filed Dec 4, 2006 20:37 UTC
POWER JOHANNA MESSINAVP & Controller
SaleCommon Stock 300 $43.87 $13,161.00
Disclosure

SEC source: 0000875320-06-000106 · edgar.xml · nonDerivative · entry 1

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,297

F1 · kind: Transaction made pursuant to Ms. Messina-Power's company approved trading plan established under Rule 10b5-1.

Read SEC document
December 01, 2006 Filed Dec 4, 2006 20:46 UTC Exercise / conversionStock Option · Derivative 3,000 $0.00 Strike: $13.23 $0.00
Disclosure

SEC source: 0000875320-06-000107 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,000

Underlying: Common Stock · 3,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan. Fully vested.

Read SEC document
December 01, 2006 Filed Dec 4, 2006 20:46 UTC SaleCommon Stock 3,000 $43.86 $131,580.00
Disclosure

SEC source: 0000875320-06-000107 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,000

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan established under Rule 10b5-1.

Read SEC document
December 01, 2006 Filed Dec 4, 2006 20:46 UTC Exercise / conversionComon Stock 3,000 $13.23 $39,690.00
Disclosure

SEC source: 0000875320-06-000107 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 30, 2006 Filed Dec 1, 2006 18:55 UTC Exercise / conversionStock Option · Derivative 3,000 $0.00 Strike: $13.23 $0.00
Disclosure

SEC source: 0000875320-06-000105 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,000

Underlying: Common Stock · 3,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan. Fully vested.

Read SEC document
November 30, 2006 Filed Dec 1, 2006 18:55 UTC SaleCommon Stock 3,000 $44.54 $133,620.00
Disclosure

SEC source: 0000875320-06-000105 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,000

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan established under Rule 10b5-1.

Read SEC document
November 30, 2006 Filed Dec 1, 2006 18:55 UTC Exercise / conversionComon Stock 3,000 $13.23 $39,690.00
Disclosure

SEC source: 0000875320-06-000105 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 29, 2006 Filed Nov 30, 2006 20:01 UTC
ALAM JOHN JEVP, Medicines Dev. & CMO
Exercise / conversionStock Option · Derivative 500 $0.00 Strike: $9.07 $0.00
Disclosure

SEC source: 0000875320-06-000104 · edgar.xml · derivative · entry 6

ALAM JOHN J · CIK 0001197014 · EVP, Medicines Dev. & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 504,495

Underlying: Common Stock · 500 shares

Expires 2013-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 4 years from 12/11/2003.

Read SEC document
November 29, 2006 Filed Nov 30, 2006 20:01 UTC
ALAM JOHN JEVP, Medicines Dev. & CMO
Exercise / conversionStock Option · Derivative 1,000 $0.00 Strike: $18.47 $0.00
Disclosure

SEC source: 0000875320-06-000104 · edgar.xml · derivative · entry 5

ALAM JOHN J · CIK 0001197014 · EVP, Medicines Dev. & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 504,995

Underlying: Common Stock · 1,000 shares

Expires 2007-09-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 9/26/1997.

Read SEC document
November 29, 2006 Filed Nov 30, 2006 20:01 UTC
ALAM JOHN JEVP, Medicines Dev. & CMO
SaleCommon Stock 1,500 $44.21 $66,315.00
Disclosure

SEC source: 0000875320-06-000104 · edgar.xml · nonDerivative · entry 3

ALAM JOHN J · CIK 0001197014 · EVP, Medicines Dev. & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,856

F1 · kind: Transaction made pursuant to Dr. Alam's company approved trading plan established under Rule 10b5-1.

Read SEC document
November 29, 2006 Filed Nov 30, 2006 20:01 UTC
ALAM JOHN JEVP, Medicines Dev. & CMO
Exercise / conversionCommon Stock 500 $9.07 $4,535.00
Disclosure

SEC source: 0000875320-06-000104 · edgar.xml · nonDerivative · entry 2

ALAM JOHN J · CIK 0001197014 · EVP, Medicines Dev. & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,356

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 29, 2006 Filed Nov 30, 2006 20:01 UTC
ALAM JOHN JEVP, Medicines Dev. & CMO
Exercise / conversionCommon Stock 1,000 $18.47 $18,470.00
Disclosure

SEC source: 0000875320-06-000104 · edgar.xml · nonDerivative · entry 1

ALAM JOHN J · CIK 0001197014 · EVP, Medicines Dev. & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,856

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 28, 2006 Filed Nov 29, 2006 18:51 UTC
BOGER JOSHUA SDirector · President & CEO
Exercise / conversionStock Option · Derivative 11,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000103 · edgar.xml · derivative · entry 5

BOGER JOSHUA S · CIK 0001197023 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,993,531

Underlying: Common Stock · 11,000 shares

Expires 2006-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Right to buy under 1994 Stock and Option Plan, vesting quarterly over 5 years from 12/12/1996.

Read SEC document
November 28, 2006 Filed Nov 29, 2006 18:51 UTC
BOGER JOSHUA SDirector · President & CEO
SaleCommon Stock 11,000 $43.55 $479,050.00
Disclosure

SEC source: 0000875320-06-000103 · edgar.xml · nonDerivative · entry 2

BOGER JOSHUA S · CIK 0001197023 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,035,403

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

Read SEC document
November 28, 2006 Filed Nov 29, 2006 18:51 UTC
BOGER JOSHUA SDirector · President & CEO
Exercise / conversionCommon Stock 11,000 $15.56 $171,160.00
Disclosure

SEC source: 0000875320-06-000103 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,046,403

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 27, 2006 Filed Nov 28, 2006 17:23 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock · Derivative 250 $0.00 Strike: $9.07 $0.00
Disclosure

SEC source: 0000875320-06-000102 · edgar.xml · derivative · entry 4

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,210

Underlying: Common Stock · 250 shares

Expires 2013-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 20 equal quarterly installments from 12/11/2003.

Read SEC document
November 27, 2006 Filed Nov 28, 2006 17:23 UTC
POWER JOHANNA MESSINAVP & Controller
SaleCommon Stock 250 $43.72 $10,930.00
Disclosure

SEC source: 0000875320-06-000102 · edgar.xml · nonDerivative · entry 2

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,597

F1 · kind: Transaction made pursuant to Ms. Messina-Power's company approved trading plan established under Rule 10b5-1.

Read SEC document
November 27, 2006 Filed Nov 28, 2006 17:23 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock 250 $9.07 $2,267.50
Disclosure

SEC source: 0000875320-06-000102 · edgar.xml · nonDerivative · entry 1

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,847

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 22, 2006 Filed Nov 27, 2006 15:54 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
Exercise / conversionStock Option · Derivative 1,500 $0.00 Strike: $18.47 $0.00
Disclosure

SEC source: 0000875320-06-000101 · edgar.xml · derivative · entry 4

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 505,995

Underlying: Common Stock · 1,500 shares

Expires 2007-09-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 9/26/1997.

Read SEC document
November 22, 2006 Filed Nov 27, 2006 15:54 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
SaleCommon Stock 1,500 $44.36 $66,540.00
Disclosure

SEC source: 0000875320-06-000101 · edgar.xml · nonDerivative · entry 2

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,563

F1 · kind: Transaction made pursuant to Dr. Alam's company approved trading plan established under Rule 10b5-1.

Read SEC document
November 22, 2006 Filed Nov 27, 2006 15:54 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
Exercise / conversionCommon Stock 1,500 $18.47 $27,705.00
Disclosure

SEC source: 0000875320-06-000101 · edgar.xml · nonDerivative · entry 1

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,063

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2006 Filed Nov 21, 2006 21:04 UTC
MUELLER PETERCSO&EVP Drug Innov&Realization
SaleCommon Stock 32,314 $45.00 $1,454,130.00
Disclosure

SEC source: 0000875320-06-000099 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · CSO&EVP Drug Innov&Realization

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,912

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan established under Rule 10b5-1.

Read SEC document
November 20, 2006 Filed Nov 21, 2006 21:07 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock · Derivative 250 $0.00 Strike: $11.18 $0.00
Disclosure

SEC source: 0000875320-06-000100 · edgar.xml · derivative · entry 4

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,460

Underlying: Common Stock · 250 shares

Expires 2009-06-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 20 equal quarterly installments from 06/07/1999.

Read SEC document
November 20, 2006 Filed Nov 21, 2006 21:07 UTC
POWER JOHANNA MESSINAVP & Controller
SaleCommon Stock 250 $44.83 $11,207.50
Disclosure

SEC source: 0000875320-06-000100 · edgar.xml · nonDerivative · entry 2

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,597

F1 · kind: Transaction made pursuant to Ms. Messina-Power's company approved trading plan established under Rule 10b5-1.

Read SEC document
November 20, 2006 Filed Nov 21, 2006 21:07 UTC
POWER JOHANNA MESSINAVP & Controller
Exercise / conversionCommon Stock 250 $11.18 $2,795.00
Disclosure

SEC source: 0000875320-06-000100 · edgar.xml · nonDerivative · entry 1

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,847

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 16, 2006 Filed Nov 17, 2006 19:58 UTC
MUELLER PETERCSO&EVP Drug Innov&Realization
Disposition to issuerStock Option · Derivative 17,686 $0.00 Strike: $16.32 $0.00
Disclosure

SEC source: 0000875320-06-000098 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · CSO&EVP Drug Innov&Realization

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 392,864

Underlying: Common Stock · 17,686 shares

Expires 2013-07-14

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 20 equal quarterly installments from 07/15/2003.

Read SEC document
November 16, 2006 Filed Nov 17, 2006 19:58 UTC
MUELLER PETERCSO&EVP Drug Innov&Realization
SaleCommon Stock 17,686 $45.00 $795,870.00
Disclosure

SEC source: 0000875320-06-000098 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · CSO&EVP Drug Innov&Realization

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,226

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan established under Rule 10b5-1.

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November 16, 2006 Filed Nov 17, 2006 19:58 UTC
MUELLER PETERCSO&EVP Drug Innov&Realization
Exercise / conversionCommon Stock 17,686 $16.32 $288,635.52
Disclosure

SEC source: 0000875320-06-000098 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · CSO&EVP Drug Innov&Realization

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 102,912

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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November 15, 2006 Filed Nov 16, 2006 21:20 UTC
POWER JOHANNA MESSINAVP & Controller
SaleCommon Stock 267 $43.94 $11,731.98
Disclosure

SEC source: 0000875320-06-000096 · edgar.xml · nonDerivative · entry 1

POWER JOHANNA MESSINA · CIK 0001197030 · VP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,597

F1 · kind: Transaction made pursuant to Ms. Messina-Power's company approved trading plan established under Rule 10b5-1.

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November 15, 2006 Filed Nov 16, 2006 21:23 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
Exercise / conversionStock Option · Derivative 1,500 $0.00 Strike: $18.47 $0.00
Disclosure

SEC source: 0000875320-06-000097 · edgar.xml · derivative · entry 5

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 507,495

Underlying: Common Stock · 1,500 shares

Expires 2007-09-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 9/26/1997.

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November 15, 2006 Filed Nov 16, 2006 21:23 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
SaleCommon Stock 707 $44.01 $31,115.07
Disclosure

SEC source: 0000875320-06-000097 · edgar.xml · nonDerivative · entry 3

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,856

F1 · kind: Transaction made pursuant to Dr. Alam's company approved trading plan established under Rule 10b5-1.

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November 15, 2006 Filed Nov 16, 2006 21:23 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
SaleCommon Stock 1,500 $43.55 $65,325.00
Disclosure

SEC source: 0000875320-06-000097 · edgar.xml · nonDerivative · entry 2

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,563

F1 · kind: Transaction made pursuant to Dr. Alam's company approved trading plan established under Rule 10b5-1.

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November 15, 2006 Filed Nov 16, 2006 21:23 UTC
ALAM JOHN JEVP, Med. Dev. Group & CMO
Exercise / conversionCommon Stock 1,500 $18.47 $27,705.00
Disclosure

SEC source: 0000875320-06-000097 · edgar.xml · nonDerivative · entry 1

ALAM JOHN J · CIK 0001197014 · EVP, Med. Dev. Group & CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,063

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.