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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 18, 2011 Filed Jan 20, 2011 17:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 11,914 $40.00 $476,560.00
Disclosure

SEC source: 0000875320-11-000002 · edgar.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,838

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
January 18, 2011 Filed Jan 20, 2011 17:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionCommon Stock 11,914 $18.93 $225,532.02
Disclosure

SEC source: 0000875320-11-000002 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 11, 2011 Filed Jan 13, 2011 18:26 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 451 $37.66 $16,984.66
Disclosure

SEC source: 0000875320-11-000001 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,838

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan established under Rule 10b5-1.

Read SEC document
December 15, 2010 Filed Dec 17, 2010 14:29 UTC GrantStock Option · Derivative 1,527 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0000875320-10-000060 · edgar.xml · derivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,527

Underlying: Common Stock · 1,527 shares

Expires 2020-12-14

F1 · derivative.exercise_date: Fully vested.

Read SEC document
November 15, 2010 Filed Nov 16, 2010 21:19 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 77 $34.47 $2,654.19
Disclosure

SEC source: 0000875320-10-000057 · edgar.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,877

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $34.47 (range $34.30 to $34.59).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 15, 2010 Filed Nov 16, 2010 21:20 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 1,600 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-10-000058 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,800

Underlying: Common Stock · 1,600 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
November 15, 2010 Filed Nov 16, 2010 21:20 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,600 $34.43 $55,088.00
Disclosure

SEC source: 0000875320-10-000058 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,234

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $34.43 (range $33.95 to $34.57).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 15, 2010 Filed Nov 16, 2010 21:20 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,600 $10.41 $16,656.00
Disclosure

SEC source: 0000875320-10-000058 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 15, 2010 Filed Nov 16, 2010 21:21 UTC
Silva Paul MV.P. and Corporate Controller
SaleCommon Stock 570 $34.46 $19,642.20
Disclosure

SEC source: 0000875320-10-000059 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,625

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted average price of $34.46 (range $34.30 to $34.61).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 28, 2010 Filed Oct 29, 2010 15:00 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 4,750 $38.50 $182,875.00
Disclosure

SEC source: 0000875320-10-000056 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,160

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan established under Rule 10b5-1.

Read SEC document
October 26, 2010 Filed Oct 28, 2010 18:05 UTC
Sachdev AmitSVP, Public Policy,Gov Affairs
SaleCommon Stock 4,534 $37.50 $170,025.00
Disclosure

SEC source: 0000875320-10-000055 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Public Policy,Gov Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,910

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan established under Rule 10b5-1.

Read SEC document
October 18, 2010 Filed Oct 20, 2010 16:37 UTC
Sachdev AmitSVP, Public Policy,Gov Affairs
SaleCommon Stock 1,000 $36.50 $36,500.00
Disclosure

SEC source: 0000875320-10-000054 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Public Policy,Gov Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,444

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan established under Rule 10b5-1.

Read SEC document
October 15, 2010 Filed Oct 18, 2010 19:06 UTC
Sachdev AmitSVP, Public Policy,Gov Affairs
SaleCommon Stock 1,000 $35.00 $35,000.00
Disclosure

SEC source: 0000875320-10-000052 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Public Policy,Gov Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,444

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan established under Rule 10b5-1.

Read SEC document
October 15, 2010 Filed Oct 18, 2010 19:08 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 1,600 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-10-000053 · edgar.xml · derivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,400

Underlying: Common Stock · 1,600 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
October 15, 2010 Filed Oct 18, 2010 19:08 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 330 $36.02 $11,886.60
Disclosure

SEC source: 0000875320-10-000053 · edgar.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,234

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $36.02 (range ($35.96 to $36.10).

F4 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 15, 2010 Filed Oct 18, 2010 19:08 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,270 $35.55 $45,148.50
Disclosure

SEC source: 0000875320-10-000053 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,564

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $35.55 (range $34.88 to $35.87).

F4 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 15, 2010 Filed Oct 18, 2010 19:08 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,600 $10.41 $16,656.00
Disclosure

SEC source: 0000875320-10-000053 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 15, 2010 Filed Sep 16, 2010 19:53 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 1,600 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-10-000050 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 1,600 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
September 15, 2010 Filed Sep 16, 2010 19:53 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,600 $37.22 $59,552.00
Disclosure

SEC source: 0000875320-10-000050 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,234

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $37.22 (range $37.08 to $37.36).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
September 15, 2010 Filed Sep 16, 2010 19:53 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,600 $10.41 $16,656.00
Disclosure

SEC source: 0000875320-10-000050 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 16, 2010 Filed Aug 17, 2010 18:08 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 1,600 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-10-000049 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,600

Underlying: Common Stock · 1,600 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
August 16, 2010 Filed Aug 17, 2010 18:08 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,600 $36.38 $58,208.00
Disclosure

SEC source: 0000875320-10-000049 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,234

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $36.38 (range $36.02 to $36.54).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 16, 2010 Filed Aug 17, 2010 18:08 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,600 $10.41 $16,656.00
Disclosure

SEC source: 0000875320-10-000049 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 02, 2010 Filed Aug 3, 2010 16:08 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 307 $34.17 $10,490.19
Disclosure

SEC source: 0000875320-10-000048 · edgar.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,256

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan established under Rule 10b5-1.

Read SEC document
July 15, 2010 Filed Jul 16, 2010 20:02 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 1,600 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-10-000047 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,200

Underlying: Common Stock · 1,600 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
July 15, 2010 Filed Jul 16, 2010 20:02 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,600 $34.24 $54,784.00
Disclosure

SEC source: 0000875320-10-000047 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,234

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $34.24 (range $34.04 to $34.50).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 15, 2010 Filed Jul 16, 2010 20:02 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,600 $10.41 $16,656.00
Disclosure

SEC source: 0000875320-10-000047 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:50 UTC
BOGER KENNETH SSVP & General Counsel
GrantStock Option · Derivative 30,500 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000040 · edgar.xml · derivative · entry 1

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,500

Underlying: Common STock · 30,500 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:52 UTC
SMITH IAN FEVP & CFO
GrantStock Option · Derivative 36,250 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000041 · edgar.xml · derivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,250

Underlying: Common Stock · 36,250 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:53 UTC
Wysenski NancyEVP & Chief Commercial Officer
GrantStock Options · Derivative 36,250 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000042 · edgar.xml · derivative · entry 1

Wysenski Nancy · CIK 0001294596 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,250

Underlying: Common Stock · 36,250 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:54 UTC
Emmens MatthewDirector · President & CEO
GrantStock Option · Derivative 118,000 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000043 · edgar.xml · derivative · entry 1

Emmens Matthew · CIK 0001298332 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,000

Underlying: Common Stock · 118,000 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:55 UTC
Kelly LisaSVP, Human Resources
GrantStock Options · Derivative 30,500 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000044 · edgar.xml · derivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,500

Underlying: Common Stock · 30,500 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:56 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
GrantStock Option · Derivative 30,500 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000045 · edgar.xml · derivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,500

Underlying: Common Stock · 30,500 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:57 UTC
Silva Paul MV.P. and Corporate Controller
GrantStock Options · Derivative 7,500 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000046 · edgar.xml · derivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 7,500 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 20:02 UTC
MUELLER PETEREVP, Global R&D, CSO
GrantStock Option · Derivative 36,250 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000047 · edgar.xml · derivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,250

Underlying: Common Stock · 36,250 shares

Expires 2020-07-13

F5 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
July 09, 2010 Filed Jul 13, 2010 20:42 UTC GrantStock Options · Derivative 30,000 $0.00 Strike: $33.89 $0.00
Disclosure

SEC source: 0000875320-10-000039 · edgar.xml · derivative · entry 1

Riley Wayne Joseph · CIK 0001432895 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2020-07-08

F1 · shares: Right to buy under 2006 Stock and Option Plan, vesting in 16 equal quarterly installments over four years.

Read SEC document
July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionStock Option · Derivative 10,000 $0.00 Strike: $13.32 $0.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · derivative · entry 8

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2015-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Fully vested.

Read SEC document
July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $9.09 $0.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · derivative · entry 7

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2014-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Fully vested.

Read SEC document
July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $14.46 $0.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · derivative · entry 6

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2013-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Fully vested.

Read SEC document
July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $19.84 $0.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · derivative · entry 5

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2012-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Fully vested.

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July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionCommon Stock 10,000 $13.32 $133,200.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · nonDerivative · entry 4

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 201,210

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionCommon Stock 7,500 $9.09 $68,175.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · nonDerivative · entry 3

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 191,210

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionCommon Stock 7,500 $14.46 $108,450.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · nonDerivative · entry 2

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,710

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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July 02, 2010 Filed Jul 6, 2010 21:19 UTC Exercise / conversionCommon Stock 7,500 $19.84 $148,800.00
Disclosure

SEC source: 0000875320-10-000036 · edgar.xml · nonDerivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,210

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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June 28, 2010 Filed Jun 29, 2010 18:50 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 876 $34.73 $30,423.48
Disclosure

SEC source: 0000875320-10-000035 · edgar.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,563

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $34.73 (range $34.40 to $35.11).

F3 · price: Ms. Kelly-Croswell undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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June 15, 2010 Filed Jun 16, 2010 16:28 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 1,600 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-10-000034 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,800

Underlying: Common Stock · 1,600 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

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June 15, 2010 Filed Jun 16, 2010 16:28 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,600 $34.93 $55,888.00
Disclosure

SEC source: 0000875320-10-000034 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,234

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $34.93 (range $34.78 to $35.09).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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June 15, 2010 Filed Jun 16, 2010 16:28 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,600 $10.41 $16,656.00
Disclosure

SEC source: 0000875320-10-000034 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2010 Filed Jun 2, 2010 19:25 UTC GrantStock Option · Derivative 40,000 $0.00 Strike: $34.24 $0.00
Disclosure

SEC source: 0000875320-10-000026 · edgar.xml · derivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2020-05-31

F1 · derivative.exercise_date: Fully vested.

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June 01, 2010 Filed Jun 2, 2010 19:26 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $34.24 $0.00
Disclosure

SEC source: 0000875320-10-000027 · edgar.xml · derivative · entry 1

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2020-05-31

F1 · derivative.exercise_date: Fully vested.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.