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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 10, 2011 Filed Mar 11, 2011 16:07 UTC
Silva Paul MVP & Corp Controller
SaleCommon Stock 1,525 $45.73 $69,738.25
Disclosure

SEC source: 0001209191-11-017266 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,100

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $45.73 (range $45.22 to $45.99).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 03, 2011 Filed Mar 4, 2011 20:29 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionStock Option · Derivative 9,531 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-11-015485 · doc4.xml · derivative · entry 4

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,062

Underlying: Common Stock · 9,531 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/07/2008, except that the first quarterly vesting occurred on May 15, 2008.

Read SEC document
March 03, 2011 Filed Mar 4, 2011 20:29 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 9,531 $49.50 $471,784.50
Disclosure

SEC source: 0001209191-11-015485 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,154

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
March 03, 2011 Filed Mar 4, 2011 20:29 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionCommon Stock 9,531 $18.93 $180,421.83
Disclosure

SEC source: 0001209191-11-015485 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,685

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 03, 2011 Filed Mar 4, 2011 20:35 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionStock Option · Derivative 13,343 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-11-015489 · doc4.xml · derivative · entry 4

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,157

Underlying: Common Stock · 13,343 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/12/2007.

Read SEC document
March 03, 2011 Filed Mar 4, 2011 20:35 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 13,343 $50.00 $667,150.00
Disclosure

SEC source: 0001209191-11-015489 · doc4.xml · nonDerivative · entry 2

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

Read SEC document
March 03, 2011 Filed Mar 4, 2011 20:35 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionCommon Stock 13,343 $28.84 $384,812.12
Disclosure

SEC source: 0001209191-11-015489 · doc4.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,585

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 02, 2011 Filed Mar 3, 2011 20:28 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionStock Option · Derivative 11,438 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-11-014962 · doc4.xml · derivative · entry 4

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,625

Underlying: Common Stock · 11,438 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/07/2008, except that the first quarterly vesting occurred on May 15, 2008.

Read SEC document
March 02, 2011 Filed Mar 3, 2011 20:28 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 11,438 $47.50 $543,305.00
Disclosure

SEC source: 0001209191-11-014962 · doc4.xml · nonDerivative · entry 2

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

Read SEC document
March 02, 2011 Filed Mar 3, 2011 20:28 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionCommon Stock 11,438 $18.93 $216,521.34
Disclosure

SEC source: 0001209191-11-014962 · doc4.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,680

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:32 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionStock Option · Derivative 11,915 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0000875320-11-000019 · edgar.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,593

Underlying: Common Stock · 11,915 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/07/2008, except that the first quarterly vesting occurred on May 15, 2008.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:32 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 3,972 $45.00 $178,740.00
Disclosure

SEC source: 0000875320-11-000019 · edgar.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,154

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:32 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 11,915 $46.00 $548,090.00
Disclosure

SEC source: 0000875320-11-000019 · edgar.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,126

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:32 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionCommon Stock 11,915 $18.93 $225,550.95
Disclosure

SEC source: 0000875320-11-000019 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:36 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionStock Option · Derivative 11,437 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0000875320-11-000020 · edgar.xml · derivative · entry 4

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,063

Underlying: Common Stock · 11,437 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/07/2008, except that the first quarterly vesting occurred on May 15, 2008.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:36 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 11,437 $45.00 $514,665.00
Disclosure

SEC source: 0000875320-11-000020 · edgar.xml · nonDerivative · entry 2

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

Read SEC document
February 28, 2011 Filed Mar 1, 2011 21:36 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionCommon Stock 11,437 $18.93 $216,502.41
Disclosure

SEC source: 0000875320-11-000020 · edgar.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,679

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 23, 2011 Filed Feb 24, 2011 21:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionStock Option · Derivative 23,828 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0000875320-11-000018 · edgar.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,446

Underlying: Common Stock · 23,828 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/07/2008, except that the first quarterly vesting occurred on May 15, 2008.

Read SEC document
February 23, 2011 Filed Feb 24, 2011 21:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 11,914 $44.00 $524,216.00
Disclosure

SEC source: 0000875320-11-000018 · edgar.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,126

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
February 23, 2011 Filed Feb 24, 2011 21:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 11,914 $43.60 $519,450.40
Disclosure

SEC source: 0000875320-11-000018 · edgar.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,040

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
February 23, 2011 Filed Feb 24, 2011 21:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionCommon Stock 23,828 $18.93 $451,064.04
Disclosure

SEC source: 0000875320-11-000018 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,954

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 07, 2011 Filed Feb 9, 2011 20:09 UTC GiftCommon Stock 39,000 $0.00 $0.00
Disclosure

SEC source: 0000875320-11-000017 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 727,395

F1 · shares: Common stock given to family members.

Read SEC document
February 06, 2011 Filed Feb 7, 2012 21:29 UTC
Emmens MatthewExecutive Chairman
SaleCommon Stock 40,600 $38.08 $1,546,048.00
Disclosure

SEC source: 0001209191-12-008147 · doc4.xml · nonDerivative · entry 3

Emmens Matthew · CIK 0001298332 · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 211,601

F1 · kind: Transaction made pursuant to Mr. Emmens' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Emmens undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $38.08 (range $37.70 to $38.33).

Read SEC document
February 06, 2011 Filed Feb 7, 2012 21:29 UTC
Emmens MatthewExecutive Chairman
SaleCommon Stock 12,900 $37.11 $478,719.00
Disclosure

SEC source: 0001209191-12-008147 · doc4.xml · nonDerivative · entry 2

Emmens Matthew · CIK 0001298332 · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 252,201

F1 · kind: Transaction made pursuant to Mr. Emmens' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Emmens undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $37.11 (range $36.68 to $37.67).

Read SEC document
February 06, 2011 Filed Feb 7, 2012 21:29 UTC
Emmens MatthewExecutive Chairman
SaleCommon Stock 2,500 $36.39 $90,975.00
Disclosure

SEC source: 0001209191-12-008147 · doc4.xml · nonDerivative · entry 1

Emmens Matthew · CIK 0001298332 · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 265,101

F1 · kind: Transaction made pursuant to Mr. Emmens' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $36.39 (range $35.64 to $36.61).

F3 · price: Mr. Emmens undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:52 UTC
Emmens MatthewDirector · President & CEO
GrantStock Option · Derivative 236,000 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000008 · edgar.xml · derivative · entry 2

Emmens Matthew · CIK 0001298332 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 236,000

Underlying: Common Stock · 236,000 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:52 UTC
Emmens MatthewDirector · President & CEO
GrantCommon Stock 47,201 $0.01 $472.01
Disclosure

SEC source: 0000875320-11-000008 · edgar.xml · nonDerivative · entry 1

Emmens Matthew · CIK 0001298332 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,406

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:53 UTC
BOGER KENNETH SSVP & General Counsel
GrantStock Options · Derivative 45,750 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000009 · edgar.xml · derivative · entry 3

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,750

Underlying: Common Stock · 45,750 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:53 UTC
BOGER KENNETH SSVP & General Counsel
GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0000875320-11-000009 · edgar.xml · nonDerivative · entry 1

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,752

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:54 UTC
SMITH IAN FEVP & CFO
GrantStock Option · Derivative 54,375 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000010 · edgar.xml · derivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,375

Underlying: Common Stock · 54,375 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:54 UTC
SMITH IAN FEVP & CFO
GrantCommon Stock 12,084 $0.01 $120.84
Disclosure

SEC source: 0000875320-11-000010 · edgar.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,877

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:56 UTC
MUELLER PETERDirector · EVP, Global R&D, CSO
GrantStock Option · Derivative 72,500 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000011 · edgar.xml · derivative · entry 3

MUELLER PETER · CIK 0001256126 · Director · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,500

Underlying: Common Stock · 72,500 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:56 UTC
MUELLER PETERDirector · EVP, Global R&D, CSO
GrantCommon Stock 14,501 $0.01 $145.01
Disclosure

SEC source: 0000875320-11-000011 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · Director · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,735

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:57 UTC
Wysenski NancyEVP & Chief Commercial Officer
GrantStock Option · Derivative 54,375 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000012 · edgar.xml · derivative · entry 2

Wysenski Nancy · CIK 0001294596 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,375

Underlying: Common Stock · 54,375 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:57 UTC
Wysenski NancyEVP & Chief Commercial Officer
GrantCommon Stock 12,084 $0.01 $120.84
Disclosure

SEC source: 0000875320-11-000012 · edgar.xml · nonDerivative · entry 1

Wysenski Nancy · CIK 0001294596 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,084

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:57 UTC
Kelly LisaSVP, Human Resources
GrantStock Option · Derivative 45,750 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000013 · edgar.xml · derivative · entry 3

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,750

Underlying: Common Stock · 45,750 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:57 UTC
Kelly LisaSVP, Human Resources
GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0000875320-11-000013 · edgar.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:58 UTC
Silva Paul MV.P. and Corporate Controller
GrantStock Option · Derivative 15,000 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000014 · edgar.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

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February 03, 2011 Filed Feb 7, 2011 19:58 UTC
Silva Paul MV.P. and Corporate Controller
GrantCommon Stock 3,000 $0.01 $30.00
Disclosure

SEC source: 0000875320-11-000014 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,625

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

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February 03, 2011 Filed Feb 7, 2011 20:00 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
GrantStock Option · Derivative 45,750 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000015 · edgar.xml · derivative · entry 3

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,750

Underlying: Common Stock · 45,750 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

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February 03, 2011 Filed Feb 7, 2011 20:00 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0000875320-11-000015 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,126

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

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February 03, 2011 Filed Feb 7, 2011 20:01 UTC
Stamoulis ChristianaSVP, Corp Strategy & Bus Devlp
GrantStock Option · Derivative 58,250 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000016 · edgar.xml · derivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,250

Underlying: Common Stock · 58,250 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

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February 03, 2011 Filed Feb 7, 2011 20:01 UTC
Stamoulis ChristianaSVP, Corp Strategy & Bus Devlp
GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0000875320-11-000016 · edgar.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,813

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

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January 25, 2011 Filed Jan 26, 2011 20:25 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 6,042 $40.71 $245,969.82
Disclosure

SEC source: 0000875320-11-000007 · edgar.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,793

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $40.71 (range $40.66 to $40.72).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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January 25, 2011 Filed Jan 26, 2011 20:23 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 471 $40.78 $19,207.38
Disclosure

SEC source: 0000875320-11-000006 · edgar.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,076

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan established under Rule 10b5-1.

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January 21, 2011 Filed Jan 25, 2011 18:09 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 6,042 $39.93 $241,257.06
Disclosure

SEC source: 0000875320-11-000003 · edgar.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,835

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $39.93 (range $39.75 to $40.04).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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January 21, 2011 Filed Jan 25, 2011 18:10 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 2,128 $39.92 $84,949.76
Disclosure

SEC source: 0000875320-11-000004 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,960

F1 · kind: Transaction made pursuant to Mr. Sachdev's comany approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $39.92 (range $39.77 to $40.02).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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January 21, 2011 Filed Jan 25, 2011 18:11 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 1,709 $39.93 $68,240.37
Disclosure

SEC source: 0000875320-11-000005 · edgar.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,547

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $39.93 (range $39.81 to 40.02).

F3 · price: Ms. Kelly-Croswell undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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January 18, 2011 Filed Jan 20, 2011 17:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
Exercise / conversionStock Option · Derivative 11,914 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0000875320-11-000002 · edgar.xml · derivative · entry 5

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,336

Underlying: Common Stock · 11,914 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/07/2008, except that the first quarterly vesting occurred on May 15, 2008.

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January 18, 2011 Filed Jan 20, 2011 17:33 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 3,750 $39.50 $148,125.00
Disclosure

SEC source: 0000875320-11-000002 · edgar.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,088

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.