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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 17, 2011 Filed May 18, 2011 17:47 UTC
Silva Paul MVP & Corp Controller
SaleCommon Stock 467 $56.63 $26,446.21
Disclosure

SEC source: 0001209191-11-029276 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,734

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $56.63 (range $56.34 to $56.99).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 17, 2011 Filed May 18, 2011 17:49 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 300 $57.32 $17,196.00
Disclosure

SEC source: 0001209191-11-029277 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,877

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $57.32 (range $57.00 to $57.60).

Read SEC document
May 17, 2011 Filed May 18, 2011 17:49 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 409 $56.58 $23,141.22
Disclosure

SEC source: 0001209191-11-029277 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,177

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $56.58 (range $56.34 to $56.97).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 17, 2011 Filed May 18, 2011 18:28 UTC GrantStock Option · Derivative 30,000 $0.00 Strike: $56.99 $0.00
Disclosure

SEC source: 0001209191-11-029317 · doc4.xml · derivative · entry 1

Kearney Terrence C · CIK 0001289098 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2021-05-16

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 05/17/2011.

Read SEC document
May 16, 2011 Filed May 18, 2011 17:45 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Options · Derivative 2,500 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0001209191-11-029274 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,300

Underlying: Common Stock · 2,500 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
May 16, 2011 Filed May 18, 2011 17:45 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,700 $57.21 $97,257.00
Disclosure

SEC source: 0001209191-11-029274 · doc4.xml · nonDerivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,735

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $57.21 (range $57.00 to $57.49).

Read SEC document
May 16, 2011 Filed May 18, 2011 17:45 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 700 $56.79 $39,753.00
Disclosure

SEC source: 0001209191-11-029274 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 135,435

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $56.79 (range $56.61 to $56.92).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 16, 2011 Filed May 18, 2011 17:45 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 100 $55.44 $5,544.00
Disclosure

SEC source: 0001209191-11-029274 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136,135

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

Read SEC document
May 16, 2011 Filed May 18, 2011 17:45 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 2,500 $10.41 $26,025.00
Disclosure

SEC source: 0001209191-11-029274 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136,235

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 12, 2011 Filed May 13, 2011 18:57 UTC GrantStock Option · Derivative 30,000 $0.00 Strike: $57.27 $0.00
Disclosure

SEC source: 0001209191-11-028289 · doc4.xml · derivative · entry 1

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2021-05-11

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan vesting in 16 quarterly installments from 05/12/2011.

Read SEC document
May 11, 2011 Filed May 12, 2011 15:40 UTC Exercise / conversionStock Option · Derivative 4,000 $0.00 Strike: $24.66 $0.00
Disclosure

SEC source: 0001209191-11-027832 · doc4.xml · derivative · entry 5

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,946

Underlying: Common Stock · 4,000 shares

Expires 2011-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
May 11, 2011 Filed May 12, 2011 15:40 UTC SaleCommon Stock 1,900 $56.27 $106,913.00
Disclosure

SEC source: 0001209191-11-027832 · doc4.xml · nonDerivative · entry 3

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 727,395

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan under Rule 10b5-1.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $56.27 (range $56.02 to $56.70).

Read SEC document
May 11, 2011 Filed May 12, 2011 15:40 UTC SaleCommon Stock 2,100 $55.66 $116,886.00
Disclosure

SEC source: 0001209191-11-027832 · doc4.xml · nonDerivative · entry 2

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 729,295

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $55.66 (range $55.40 to $55.97).

Read SEC document
May 11, 2011 Filed May 12, 2011 15:40 UTC Exercise / conversionCommon Stock 4,000 $24.66 $98,640.00
Disclosure

SEC source: 0001209191-11-027832 · doc4.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 731,395

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2011 Filed May 10, 2011 20:10 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionStock Option · Derivative 1,906 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-11-027255 · doc4.xml · derivative · entry 6

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,719

Underlying: Common Stock · 1,906 shares

Expires 2018-05-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan vesting in 16 quarterly installments from 02/07/2008.

Read SEC document
May 09, 2011 Filed May 10, 2011 20:10 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 1,076 $57.53 $61,902.28
Disclosure

SEC source: 0001209191-11-027255 · doc4.xml · nonDerivative · entry 4

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

F3 · price: Ms. Kelly-Croswell undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $57.53 (range $57.13 to $57.90).

Read SEC document
May 09, 2011 Filed May 10, 2011 20:10 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 530 $56.69 $30,045.70
Disclosure

SEC source: 0001209191-11-027255 · doc4.xml · nonDerivative · entry 3

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,318

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

F3 · price: Ms. Kelly-Croswell undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $56.69 (range $56.22 to $56.97).

Read SEC document
May 09, 2011 Filed May 10, 2011 20:10 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 300 $55.72 $16,716.00
Disclosure

SEC source: 0001209191-11-027255 · doc4.xml · nonDerivative · entry 2

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,848

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $55.72 (range $55.52 to $55.90).

F3 · price: Ms. Kelly-Croswell undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 09, 2011 Filed May 10, 2011 20:10 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionCommon Stock 1,906 $18.93 $36,080.58
Disclosure

SEC source: 0001209191-11-027255 · doc4.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,148

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 02, 2011 Filed May 3, 2011 19:05 UTC
BOGER KENNETH SSVP & General Counsel
Exercise / conversionStock Option · Derivative 5,000 $0.00 Strike: $24.66 $0.00
Disclosure

SEC source: 0001209191-11-025599 · doc4.xml · derivative · entry 6

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,000 shares

Expires 2011-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
May 02, 2011 Filed May 3, 2011 19:05 UTC
BOGER KENNETH SSVP & General Counsel
SaleCommon Stock 1,386 $56.01 $77,629.86
Disclosure

SEC source: 0001209191-11-025599 · doc4.xml · nonDerivative · entry 3

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,752

F1 · kind: Transaction made pursuant to Mr. Boger's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $56.01 (range $55.90 to $56.48).

Read SEC document
May 02, 2011 Filed May 3, 2011 19:05 UTC
BOGER KENNETH SSVP & General Counsel
SaleCommon Stock 3,614 $55.57 $200,829.98
Disclosure

SEC source: 0001209191-11-025599 · doc4.xml · nonDerivative · entry 2

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,138

F1 · kind: Transaction made pursuant to Mr. Boger's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $55.57 (range $55.06 to $55.88).

F3 · price: Mr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 02, 2011 Filed May 3, 2011 19:05 UTC
BOGER KENNETH SSVP & General Counsel
Exercise / conversionCommon Stock 5,000 $24.66 $123,300.00
Disclosure

SEC source: 0001209191-11-025599 · doc4.xml · nonDerivative · entry 1

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 27, 2011 Filed Apr 27, 2011 20:09 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionStock Option · Derivative 14,297 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-11-024585 · doc4.xml · derivative · entry 4

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,907

Underlying: Common Stock · 14,297 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/12/2007.

Read SEC document
April 27, 2011 Filed May 3, 2011 19:06 UTC GiftCommon Stock 20,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-11-025601 · doc4.xml · nonDerivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 181,210

F1 · shares: Common stock gifted to a charitable entity.

Read SEC document
April 26, 2011 Filed Apr 27, 2011 20:09 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 14,297 $50.50 $721,998.50
Disclosure

SEC source: 0001209191-11-024585 · doc4.xml · nonDerivative · entry 2

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

Read SEC document
April 26, 2011 Filed Apr 27, 2011 20:09 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionCommon Stock 14,297 $28.84 $412,325.48
Disclosure

SEC source: 0001209191-11-024585 · doc4.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,539

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 25, 2011 Filed Apr 26, 2011 19:40 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionStock Option · Derivative 953 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-11-024395 · doc4.xml · derivative · entry 4

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,204

Underlying: Common Stock · 953 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 7/12/2007.

Read SEC document
April 25, 2011 Filed Apr 26, 2011 19:40 UTC
Kelly LisaSVP, Human Resources
SaleCommon Stock 953 $50.00 $47,650.00
Disclosure

SEC source: 0001209191-11-024395 · doc4.xml · nonDerivative · entry 2

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,242

F1 · kind: Transaction made pursuant to Ms. Kelly-Croswell's company approved trading plan under Rule 10b5-1.

Read SEC document
April 25, 2011 Filed Apr 26, 2011 19:40 UTC
Kelly LisaSVP, Human Resources
Exercise / conversionCommon Stock 953 $28.84 $27,484.52
Disclosure

SEC source: 0001209191-11-024395 · doc4.xml · nonDerivative · entry 1

Kelly Lisa · CIK 0001349077 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 25, 2011 Filed Apr 26, 2011 19:41 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 12,500 $0.00 Strike: $16.32 $0.00
Disclosure

SEC source: 0001209191-11-024396 · doc4.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 12,500 shares

Expires 2013-07-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 25, 2011 Filed Apr 26, 2011 19:41 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 12,500 $50.00 $625,000.00
Disclosure

SEC source: 0001209191-11-024396 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,735

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

Read SEC document
April 25, 2011 Filed Apr 26, 2011 19:41 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 12,500 $16.32 $204,000.00
Disclosure

SEC source: 0001209191-11-024396 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,235

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2011 Filed Apr 19, 2011 20:29 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 2,500 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0001209191-11-023372 · doc4.xml · derivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,800

Underlying: Common Stock · 2,500 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
April 15, 2011 Filed Apr 19, 2011 20:29 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,200 $47.71 $57,252.00
Disclosure

SEC source: 0001209191-11-023372 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,735

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $47.71 (range $47.60 to $48.10).

Read SEC document
April 15, 2011 Filed Apr 19, 2011 20:29 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,300 $47.28 $61,464.00
Disclosure

SEC source: 0001209191-11-023372 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,935

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $47.28 (range $46.88 to $47.58).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 15, 2011 Filed Apr 19, 2011 20:29 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 2,500 $10.41 $26,025.00
Disclosure

SEC source: 0001209191-11-023372 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136,235

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 11, 2011 Filed Apr 13, 2011 18:01 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 2,500 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0001209191-11-022756 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,300

Underlying: Common Stock · 2,500 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
April 11, 2011 Filed Apr 13, 2011 18:01 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option · Derivative 37,500 $0.00 Strike: $16.32 $0.00
Disclosure

SEC source: 0001209191-11-022756 · doc4.xml · derivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 112,500

Underlying: Common Stock · 37,500 shares

Expires 2013-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

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April 11, 2011 Filed Apr 13, 2011 18:01 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 21,135 $48.20 $1,018,707.00
Disclosure

SEC source: 0001209191-11-022756 · doc4.xml · nonDerivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,735

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a wieghted average price of $48.20 (range $48.00 to $48.84).

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April 11, 2011 Filed Apr 13, 2011 18:01 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 18,865 $47.83 $902,312.95
Disclosure

SEC source: 0001209191-11-022756 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 154,870

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $47.83 (range $47.57 to $47.99).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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April 11, 2011 Filed Apr 13, 2011 18:01 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 37,500 $16.32 $612,000.00
Disclosure

SEC source: 0001209191-11-022756 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 173,735

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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April 11, 2011 Filed Apr 13, 2011 18:01 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 2,500 $10.41 $26,025.00
Disclosure

SEC source: 0001209191-11-022756 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136,235

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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March 31, 2011 Filed Apr 4, 2011 18:53 UTC
BOGER KENNETH SSVP & General Counsel
OtherCommon Stock 33,333 $0.00 $0.00
Disclosure

SEC source: 0001209191-11-020912 · doc4.xml · nonDerivative · entry 1

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Indirect · Trustee of Trusts

Disclosed balance after: 174,167

F1 · kind: Kenneth S. Boger is the trustee for trusts established for the benefit of the three adult children of Joshua S. Boger (a director of the issuer) that held 207,500 shares of common stock. On March 31, 2011, one of Joshua S. Boger's children withdrew 33,333 shares of Vertex common stock from a trust formed for his benefit. Kenneth S. Boger disclaims beneficial ownership of the 174,167 shares held in the trusts.

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March 23, 2011 Filed Mar 24, 2011 17:26 UTC Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $44.47 $0.00
Disclosure

SEC source: 0001209191-11-019495 · doc4.xml · derivative · entry 3

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2011-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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March 23, 2011 Filed Mar 24, 2011 17:26 UTC SaleCommon Stock 7,235 $46.08 $333,388.80
Disclosure

SEC source: 0001209191-11-019495 · doc4.xml · nonDerivative · entry 2

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,265

F1 · price: Open market sales reported on this line occurred at a weighted average price of $46.08 (range $46.07 to $46.11).

F2 · price: Ms. Ullian undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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March 23, 2011 Filed Mar 24, 2011 17:26 UTC Exercise / conversionCommon Stock 7,500 $44.47 $333,525.00
Disclosure

SEC source: 0001209191-11-019495 · doc4.xml · nonDerivative · entry 1

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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March 17, 2011 Filed Mar 18, 2011 16:53 UTC SaleCommon Stock 2,000 $44.62 $89,240.00
Disclosure

SEC source: 0001209191-11-018838 · doc4.xml · nonDerivative · entry 1

CORDES EUGENE · CIK 0001192609 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

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March 15, 2011 Filed Feb 7, 2013 22:36 UTC GiftCommon Stock 100,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-13-007134 · doc5.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 632,895

F1 · kind: On March 15, 2011, Dr. Boger transferred 100,000 shares of Vertex common stock to a trust established for the benefit of his future grandchildren. The 100,000 shares remain in this trust as of the date of this filing.

F2 · balance_after: As of December 31, 2012.

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March 10, 2011 Filed Mar 11, 2011 16:07 UTC
Silva Paul MVP & Corp Controller
SaleCommon Stock 600 $46.24 $27,744.00
Disclosure

SEC source: 0001209191-11-017266 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $46.24 (range $46.03 to $46.70).

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.