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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 02, 2014 Filed May 6, 2014 20:30 UTC
Pace Megan ESVP, Corp. Communications
SaleCommon Stock 100 $69.42 $6,942.00
Disclosure

SEC source: 0001209191-14-031519 · doc4.xml · nonDerivative · entry 3

Pace Megan E · CIK 0001554979 · SVP, Corp. Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,350

F1 · kind: Transaction made pursuant to Ms. Pace's company approved trading plan under Rule 10b5-1.

Read SEC document
May 02, 2014 Filed May 6, 2014 20:30 UTC
Pace Megan ESVP, Corp. Communications
SaleCommon Stock 400 $67.94 $27,176.00
Disclosure

SEC source: 0001209191-14-031519 · doc4.xml · nonDerivative · entry 2

Pace Megan E · CIK 0001554979 · SVP, Corp. Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,450

F1 · kind: Transaction made pursuant to Ms. Pace's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Pace undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $67.94 (range $67.73 to $68.24).

Read SEC document
May 02, 2014 Filed May 6, 2014 20:30 UTC
Pace Megan ESVP, Corp. Communications
SaleCommon Stock 500 $67.01 $33,505.00
Disclosure

SEC source: 0001209191-14-031519 · doc4.xml · nonDerivative · entry 1

Pace Megan E · CIK 0001554979 · SVP, Corp. Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,850

F1 · kind: Transaction made pursuant to Ms. Pace's company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Pace undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $67.01 (range $66.49 to $67.40).

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option (righty to buy) · Derivative 5,750 $0.00 Strike: $32.16 $0.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · derivative · entry 10

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,500

Underlying: Common Stock · 5,750 shares

Expires 2018-07-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: Fully vested.

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option (right to buy) · Derivative 1,750 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · derivative · entry 9

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,750 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: Fully vested.

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 700 $63.27 $44,289.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · nonDerivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,750

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $63.27 (range $63.03 to $63.65).

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,800 $62.38 $112,284.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · nonDerivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 159,450

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $62.38 (range $62.00 to $62.84).

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 2,900 $61.53 $178,437.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · nonDerivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 161,250

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $61.53 (range $61.05 to $61.97).

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 2,100 $60.57 $127,197.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 164,150

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $60.57 (range $60.06 to $60.94).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 5,750 $32.16 $184,920.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 166,250

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2014 Filed Apr 17, 2014 20:12 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 1,750 $28.84 $50,470.00
Disclosure

SEC source: 0001209191-14-028131 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 09, 2014 Filed Apr 11, 2014 20:16 UTC Exercise / conversionStock Option(right to buy) · Derivative 2,500 $0.00 Strike: $34.32 $0.00
Disclosure

SEC source: 0001209191-14-027157 · doc4.xml · derivative · entry 3

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,500

Underlying: Common Stock · 2,500 shares

Expires 2016-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 09, 2014 Filed Apr 11, 2014 20:16 UTC SaleCommon Stock 2,500 $70.00 $175,000.00
Disclosure

SEC source: 0001209191-14-027157 · doc4.xml · nonDerivative · entry 2

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,265

F1 · kind: Transaction made pursuant to Ms. Ullian's company approved trading plan under Rule 10b5-1.

Read SEC document
April 09, 2014 Filed Apr 11, 2014 20:16 UTC Exercise / conversionCommon Stock 2,500 $34.32 $85,800.00
Disclosure

SEC source: 0001209191-14-027157 · doc4.xml · nonDerivative · entry 1

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,765

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 21, 2014 Filed Mar 25, 2014 20:10 UTC SaleCommon Stock 500 $76.57 $38,285.00
Disclosure

SEC source: 0001209191-14-022943 · doc4.xml · nonDerivative · entry 4

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,210

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $76.57 (range $76.22 to $76.74).

Read SEC document
March 21, 2014 Filed Mar 25, 2014 20:10 UTC SaleCommon Stock 3,000 $75.25 $225,750.00
Disclosure

SEC source: 0001209191-14-022943 · doc4.xml · nonDerivative · entry 3

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,710

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $75.25 (range $75.00 to $75.85).

Read SEC document
March 21, 2014 Filed Mar 25, 2014 20:10 UTC SaleCommon Stock 2,750 $74.47 $204,792.50
Disclosure

SEC source: 0001209191-14-022943 · doc4.xml · nonDerivative · entry 2

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,710

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $74.47 (range $73.99 to $74.96).

Read SEC document
March 21, 2014 Filed Mar 25, 2014 20:10 UTC SaleCommon Stock 2,450 $73.53 $180,148.50
Disclosure

SEC source: 0001209191-14-022943 · doc4.xml · nonDerivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,460

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $73.53 (range $72.99 to $73.98).

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 17, 2014 Filed Mar 19, 2014 20:16 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option (right to buy) · Derivative 7,500 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-14-021850 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,750

Underlying: Common Stock · 7,500 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
March 17, 2014 Filed Mar 19, 2014 20:16 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 1,220 $78.78 $96,111.60
Disclosure

SEC source: 0001209191-14-021850 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,750

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $78.78 (range $78.50 to $79.36).

Read SEC document
March 17, 2014 Filed Mar 19, 2014 20:16 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 6,280 $78.19 $491,033.20
Disclosure

SEC source: 0001209191-14-021850 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 159,970

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $78.19 (range $77.50 to $78.49).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 17, 2014 Filed Mar 19, 2014 20:16 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 7,500 $28.84 $216,300.00
Disclosure

SEC source: 0001209191-14-021850 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 166,250

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 20, 2014 Filed Feb 24, 2014 21:30 UTC SaleCommon Stock 3,200 $84.13 $269,216.00
Disclosure

SEC source: 0001209191-14-013508 · doc4.xml · nonDerivative · entry 3

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,910

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $84.13 (range $84.02 to $84.35).

Read SEC document
February 20, 2014 Filed Feb 24, 2014 21:30 UTC SaleCommon Stock 3,800 $83.65 $317,870.00
Disclosure

SEC source: 0001209191-14-013508 · doc4.xml · nonDerivative · entry 2

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,110

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $83.65 (range $83.16 to $83.99).

Read SEC document
February 20, 2014 Filed Feb 24, 2014 21:30 UTC SaleCommon Stock 1,300 $82.51 $107,263.00
Disclosure

SEC source: 0001209191-14-013508 · doc4.xml · nonDerivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,910

F1 · kind: Transaction made pursuant to Mr. Sachs' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $82.51 (range $82.00 to $82.99).

F3 · price: Mr. Sachs undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 18, 2014 Filed Feb 20, 2014 21:07 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionStock Option (right to buy) · Derivative 7,500 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-14-012316 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,250

Underlying: Common Stock · 7,500 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
February 18, 2014 Filed Feb 20, 2014 21:07 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 633 $83.05 $52,570.65
Disclosure

SEC source: 0001209191-14-012316 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,750

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $83.05 (range $82.96 to $83.18).

Read SEC document
February 18, 2014 Filed Feb 20, 2014 21:07 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 6,867 $82.55 $566,870.85
Disclosure

SEC source: 0001209191-14-012316 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 159,383

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $82.55 (range $81.95 to $82.92).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 18, 2014 Filed Feb 20, 2014 21:07 UTC
MUELLER PETEREVP, Global R&D, CSO
Exercise / conversionCommon Stock 7,500 $28.84 $216,300.00
Disclosure

SEC source: 0001209191-14-012316 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 166,250

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 07, 2014 Filed Feb 11, 2014 21:12 UTC
LEIDEN JEFFREY MDirector · CEO & President
SaleCommon Stock 35,944 $80.00 $2,875,520.00
Disclosure

SEC source: 0001209191-14-009094 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 211,481

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:02 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
GrantEmployee Stock Option (right to buy) · Derivative 68,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008348 · doc4.xml · derivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,000

Underlying: Common Stock · 68,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:02 UTC
Arbuckle Stuart AEVP\Chief Commercial Officer
GrantCommon Stock 20,700 $0.01 $207.00
Disclosure

SEC source: 0001209191-14-008348 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,418

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Connolly ThomasSVP, Human Resources
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 938 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-14-008352 · doc4.xml · derivative · entry 7

Connolly Thomas · CIK 0001453943 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,250

Underlying: Common Stock · 938 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2013.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Connolly ThomasSVP, Human Resources
GrantEmployee Stock Option (right to buy) · Derivative 62,750 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008352 · doc4.xml · derivative · entry 6

Connolly Thomas · CIK 0001453943 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,750

Underlying: Common Stock · 62,750 shares

Expires 2024-02-04

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Connolly ThomasSVP, Human Resources
SaleCommon Stock 738 $77.83 $57,438.54
Disclosure

SEC source: 0001209191-14-008352 · doc4.xml · nonDerivative · entry 4

Connolly Thomas · CIK 0001453943 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,647

F2 · kind: Transaction made pursuant to Mr. Connolly's company approved trading plan under Rule 10b5-1.

F4 · price: Mr. Connolly undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $77.83 (range $77.47 to $78.13).

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Connolly ThomasSVP, Human Resources
SaleCommon Stock 200 $76.82 $15,364.00
Disclosure

SEC source: 0001209191-14-008352 · doc4.xml · nonDerivative · entry 3

Connolly Thomas · CIK 0001453943 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,385

F2 · kind: Transaction made pursuant to Mr. Connolly's company approved trading plan under Rule 10b5-1.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $76.82 (range $76.49 to $77.14).

F4 · price: Mr. Connolly undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Connolly ThomasSVP, Human Resources
Exercise / conversionCommon Stock 938 $45.11 $42,313.18
Disclosure

SEC source: 0001209191-14-008352 · doc4.xml · nonDerivative · entry 2

Connolly Thomas · CIK 0001453943 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,585

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Connolly ThomasSVP, Human Resources
GrantCommon Stock 11,875 $0.01 $118.75
Disclosure

SEC source: 0001209191-14-008352 · doc4.xml · nonDerivative · entry 1

Connolly Thomas · CIK 0001453943 · SVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,647

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Horton Kenneth LEVP & Chief Legal Officer
GrantEmployee Stock Option (right to buy) · Derivative 51,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008354 · doc4.xml · derivative · entry 3

Horton Kenneth L · CIK 0001552047 · EVP & Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,000

Underlying: Common Stock · 51,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

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February 05, 2014 Filed Feb 7, 2014 21:04 UTC
Horton Kenneth LEVP & Chief Legal Officer
GrantCommon Stock 17,250 $0.01 $172.50
Disclosure

SEC source: 0001209191-14-008354 · doc4.xml · nonDerivative · entry 1

Horton Kenneth L · CIK 0001552047 · EVP & Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,874

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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February 05, 2014 Filed Feb 7, 2014 21:05 UTC
LEIDEN JEFFREY MDirector · CEO & President
GrantEmployee Stock Option (right to buy) · Derivative 213,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008355 · doc4.xml · derivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 213,000

Underlying: Common Stock · 213,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

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February 05, 2014 Filed Feb 7, 2014 21:05 UTC
LEIDEN JEFFREY MDirector · CEO & President
GrantCommon Stock 64,500 $0.01 $645.00
Disclosure

SEC source: 0001209191-14-008355 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 247,425

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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February 05, 2014 Filed Feb 7, 2014 21:06 UTC
MUELLER PETEREVP, Global R&D, CSO
GrantEmployee Stock Option (right to buy) · Derivative 51,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008356 · doc4.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,000

Underlying: Common Stock · 51,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

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February 05, 2014 Filed Feb 7, 2014 21:06 UTC
MUELLER PETEREVP, Global R&D, CSO
GrantCommon Stock 17,250 $0.01 $172.50
Disclosure

SEC source: 0001209191-14-008356 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,750

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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February 05, 2014 Filed Feb 7, 2014 21:06 UTC
Pace Megan ESVP, Corp. Communications
GrantEmployee Stock Option (right to buy) · Derivative 55,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008357 · doc4.xml · derivative · entry 2

Pace Megan E · CIK 0001554979 · SVP, Corp. Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,000

Underlying: Common Stock · 55,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

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February 05, 2014 Filed Feb 7, 2014 21:06 UTC
Pace Megan ESVP, Corp. Communications
GrantCommon Stock 14,250 $0.01 $142.50
Disclosure

SEC source: 0001209191-14-008357 · doc4.xml · nonDerivative · entry 1

Pace Megan E · CIK 0001554979 · SVP, Corp. Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,350

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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February 05, 2014 Filed Feb 7, 2014 21:07 UTC
Sachdev AmitSVP, Global Gov. Strategy
GrantEmployee Stock Option (right to buy) · Derivative 41,250 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008358 · doc4.xml · derivative · entry 3

Sachdev Amit · CIK 0001406338 · SVP, Global Gov. Strategy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,250

Underlying: Common Stock · 41,250 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/5/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:07 UTC
Sachdev AmitSVP, Global Gov. Strategy
GrantCommon Stock 11,875 $0.01 $118.75
Disclosure

SEC source: 0001209191-14-008358 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Global Gov. Strategy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,436

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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February 05, 2014 Filed Feb 7, 2014 21:07 UTC
Silva Paul MSVP & Corp Controller
GrantEmployee Stock Option (right to buy) · Derivative 20,625 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008359 · doc4.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,625

Underlying: Common Stock · 20,625 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:07 UTC
Silva Paul MSVP & Corp Controller
GrantCommon Stock 6,875 $0.01 $68.75
Disclosure

SEC source: 0001209191-14-008359 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,625

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.