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Nasdaq · USD

VIR

Vir Biotechnology, Inc.

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4522
SEC CIK
0001706431
Parsed reports
486

Last 12 months

Inside the activity.

0 purchase rows · 35 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202508
Dec 202502
Jan 202601
Feb 2026016
Mar 202603
Apr 202602
May 202601
Jun 202602
Jul 202600
Aug 202600
Sep 202600
Oct 202600

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
December 28, 2021 Filed Dec 30, 2021 22:00 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,375 $0.00 Strike: $1.53 $0.00
Disclosure

SEC source: 0001209191-21-071611 · doc4.xml · derivative · entry 3

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 225,005

Underlying: Common Stock · 1,375 shares

Expires 2028-01-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/4 of the shares subject to the stock option vested and became exercisable on January 8, 2019, and the remaining shares vest in 36 equal monthly installments thereafter.

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December 28, 2021 Filed Dec 30, 2021 22:00 UTC
Virgin HerbertEVP, Research & CSO
SaleCommon Stock 1,375 $39.95 $54,931.25
Disclosure

SEC source: 0001209191-21-071611 · doc4.xml · nonDerivative · entry 2

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,700

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 26, 2021.

Read SEC document
December 28, 2021 Filed Dec 30, 2021 22:00 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionCommon Stock 1,375 $1.53 $2,103.75
Disclosure

SEC source: 0001209191-21-071611 · doc4.xml · nonDerivative · entry 1

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,075

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 20, 2021 Filed Dec 21, 2021 23:13 UTC
SATO VICKI LDirector
SaleCommon Stock 2,401 $57.82 $138,825.82
Disclosure

SEC source: 0001209191-21-070835 · doc4.xml · nonDerivative · entry 5

SATO VICKI L · CIK 0001197020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,551,092

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

Read SEC document
December 20, 2021 Filed Dec 21, 2021 23:13 UTC
SATO VICKI LDirector
SaleCommon Stock 1,100 $56.10 $61,714.95
Disclosure

SEC source: 0001209191-21-070835 · doc4.xml · nonDerivative · entry 4

SATO VICKI L · CIK 0001197020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,553,493

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $56.06 to $56.21, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
December 20, 2021 Filed Dec 21, 2021 23:13 UTC
SATO VICKI LDirector
SaleCommon Stock 5,200 $55.38 $287,993.16
Disclosure

SEC source: 0001209191-21-070835 · doc4.xml · nonDerivative · entry 3

SATO VICKI L · CIK 0001197020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,554,593

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $55.00 to $55.81, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

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December 20, 2021 Filed Dec 21, 2021 23:13 UTC
SATO VICKI LDirector
SaleCommon Stock 1,300 $54.35 $70,652.01
Disclosure

SEC source: 0001209191-21-070835 · doc4.xml · nonDerivative · entry 2

SATO VICKI L · CIK 0001197020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,559,793

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $54.00 to $54.62, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
December 20, 2021 Filed Dec 21, 2021 23:13 UTC
SATO VICKI LDirector
SaleCommon Stock 5,173 $51.87 $268,298.68
Disclosure

SEC source: 0001209191-21-070835 · doc4.xml · nonDerivative · entry 1

SATO VICKI L · CIK 0001197020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,561,093

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.70 to $52.115, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
December 20, 2021 Filed Dec 22, 2021 16:30 UTC SaleCommon Stock 400,022 $52.73 $21,093,160.06
Disclosure

SEC source: 0000899243-21-049394 · doc4.xml · nonDerivative · entry 1

SVF Endurance (Cayman) Ltd · CIK 0001782338 · 10% owner

SB INVESTMENT ADVISERS (UK) LTD · CIK 0001731509 · 10% owner

SOFTBANK VISION FUND (AIV M1) L.P. · CIK 0001755143 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 22,216,644

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.90 to $57.82. The reporting person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: SVF Endurance (Cayman) Limited is the record holder of the shares of Common Stock reported herein. SVF Endurance (Cayman) Limited is a wholly owned subsidiary of SoftBank Vision Fund (AIV M1) L.P. ("SVF"). SB Investment Advisers (UK) Limited ("SBIA UK") has been appointed as alternative investment fund manager ("AIFM") and is exclusively responsible for managing SVF in accordance with the Alternative Investment Fund Managers Directive and is authorized and regulated by the UK Financial Conduct Authority accordingly. As AIFM of SVF, SBIA UK is exclusively responsible for making all decisions related to the acquisition, structuring, financing, voting and disposal of SVF's investments

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December 20, 2021 Filed Dec 22, 2021 23:00 UTC
NELSEN ROBERTDirector · 10% owner
OtherCommon Stock 102,041 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013386 · form4.xml · nonDerivative · entry 3

NELSEN ROBERT · CIK 0001219042 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 244,172

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F4 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

Read SEC document
December 20, 2021 Filed Dec 22, 2021 23:00 UTC
NELSEN ROBERTDirector · 10% owner
OtherCommon Stock 987,767 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013386 · form4.xml · nonDerivative · entry 2

NELSEN ROBERT · CIK 0001219042 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 10,677,283

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F3 · ownership.nature: The shares are directly held by ARCH Venture Fund IX Overage, L.P. ("ARCH Overage"). The Reporting Person is a managing director of ARCH Venture Partners IX, LLC, the sole general partner of ARCH Venture Partners IX Overage, L.P. ("Overage GPLP"), which is the sole general partner of ARCH Overage, and shares voting and investment control with respect to shares held by ARCH Overage. The Reporting Person disclaims ownership of such shares, except to the extent of his pecuniary interest therein.

Read SEC document
December 20, 2021 Filed Dec 22, 2021 23:00 UTC
NELSEN ROBERTDirector · 10% owner
OtherCommon Stock 762,233 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013386 · form4.xml · nonDerivative · entry 1

NELSEN ROBERT · CIK 0001219042 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 8,239,380

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F2 · ownership.nature: The shares are held by ARCH Venture Fund IX, L.P. ("ARCH IX"). The Reporting Person is a managing director of ARCH Venture Partners IX, LLC, the sole general partner of ARCH Venture Partners IX, L.P., which is the sole general partner of ARCH IX, and shares voting and investment control with respect to shares held by ARCH IX. The Reporting Person may be deemed to beneficially own the shares held by ARCH IX, and the Reporting Person disclaims ownership of such shares, except to the extent of his pecuniary interest therein.

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December 20, 2021 Filed Dec 22, 2021 22:59 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 15,504 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013385 · form4.xml · nonDerivative · entry 4

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,589

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F4 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

F6 · ownership.direct: Shares held directly by Bybee.

Read SEC document
December 20, 2021 Filed Dec 22, 2021 22:59 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 45,703 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013385 · form4.xml · nonDerivative · entry 3

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,058

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F4 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

F5 · ownership.direct: Shares held directly by Crandell.

Read SEC document
December 20, 2021 Filed Dec 22, 2021 22:59 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 987,767 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013385 · form4.xml · nonDerivative · entry 2

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 10,677,283

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F3 · ownership.nature: These shares are directly held by ARCH Venture Fund IX Overage, L.P. ("ARCH Overage"). ARCH Venture Partners IX Overage, L.P. ("Overage GPLP"), as the sole general partner of ARCH Overage, may be deemed to beneficially own the shares held by ARCH Overage. GPLLC, as the sole general partner of Overage GPLP, may be deemed to beneficially own the shares held by ARCH Overage. As managing directors of GPLLC, each of the ARCH Managing Directors may be deemed to beneficially own the shares held by ARCH Overage. Each of Overage GPLP, GPLLC and the ARCH Managing Directors disclaims beneficial ownership of the securities reported herein, except to the extent of their pecuniary interest therein, if any.

Read SEC document
December 20, 2021 Filed Dec 22, 2021 22:59 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 762,233 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-013385 · form4.xml · nonDerivative · entry 1

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 8,239,380

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F2 · ownership.nature: These shares are directly held by ARCH Venture Fund IX, L.P. ("ARCH IX"). ARCH Venture Partners IX, L.P. ("GPLP"), as the sole general partner of ARCH IX, may be deemed to beneficially own the shares held by ARCH IX. ARCH Venture Partners IX, LLC ("GPLLC"), as the sole general partner of GPLP, may be deemed to beneficially own the shares held by ARCH IX. As managing directors of GPLLC, each of Keith Crandell and Clinton Bybee (the "ARCH Managing Directors"), may be deemed to beneficially own the shares held by ARCH IX. Each of GPLP, GPLLC and the ARCH Managing Directors disclaims beneficial ownership of the securities reported herein, except to the extent of their pecuniary interest therein, if any.

Read SEC document
December 20, 2021 Filed May 10, 2022 21:26 UTC Amendment
NELSEN ROBERTDirector · 10% owner
OtherCommon Stock 102,041 $0.00 $0.00
Disclosure

SEC source: 0001062993-22-012007 · form4a.xml · nonDerivative · entry 1

NELSEN ROBERT · CIK 0001219042 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 247,546

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F2 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

F3 · ownership.direct: Correction made to include shares previously reported in prior filing on 5/21/21 but not included in the amount of shares beneficially owned in subsequent filings.

Read SEC document
December 15, 2021 Filed Dec 16, 2021 22:04 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,750 $0.00 Strike: $1.53 $0.00
Disclosure

SEC source: 0001209191-21-069994 · doc4.xml · derivative · entry 6

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 226,380

Underlying: Common Stock · 2,750 shares

Expires 2028-01-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/4 of the shares subject to the stock option vested and became exercisable on January 8, 2019, and the remaining shares vest in 36 equal monthly installments thereafter.

Read SEC document
December 15, 2021 Filed Dec 16, 2021 22:04 UTC
Virgin HerbertEVP, Research & CSO
SaleCommon Stock 2,750 $50.00 $137,500.00
Disclosure

SEC source: 0001209191-21-069994 · doc4.xml · nonDerivative · entry 4

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,700

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 26, 2021.

Read SEC document
December 15, 2021 Filed Dec 16, 2021 22:04 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionCommon Stock 2,750 $1.53 $4,207.50
Disclosure

SEC source: 0001209191-21-069994 · doc4.xml · nonDerivative · entry 3

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 110,450

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 15, 2021 Filed Dec 17, 2021 22:01 UTC
Pang PhillipChief Medical Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $1.53 $0.00
Disclosure

SEC source: 0001209191-21-070325 · doc4.xml · derivative · entry 6

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,591

Underlying: Common Stock · 5,000 shares

Expires 2018-04-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: 1/4 of the shares subject to the stock option vested and became exercisable on April 27, 2019, and the remaining shares vest in 36 equal monthly installments thereafter.

Read SEC document
December 15, 2021 Filed Dec 17, 2021 22:01 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 1,200 $52.20 $62,640.48
Disclosure

SEC source: 0001209191-21-070325 · doc4.xml · nonDerivative · entry 5

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,777

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F5 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $52.01 to $52.59 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
December 15, 2021 Filed Dec 17, 2021 22:01 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 1,034 $51.30 $53,039.75
Disclosure

SEC source: 0001209191-21-070325 · doc4.xml · nonDerivative · entry 4

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,977

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F4 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.00 to $51.95 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
December 15, 2021 Filed Dec 17, 2021 22:01 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 1,050 $50.60 $53,133.15
Disclosure

SEC source: 0001209191-21-070325 · doc4.xml · nonDerivative · entry 3

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,011

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.9825 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
December 15, 2021 Filed Dec 17, 2021 22:01 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 1,716 $49.41 $84,794.77
Disclosure

SEC source: 0001209191-21-070325 · doc4.xml · nonDerivative · entry 2

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,061

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $48.91 to $49.83 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
December 15, 2021 Filed Dec 17, 2021 22:01 UTC
Pang PhillipChief Medical Officer
Exercise / conversionCommon Stock 5,000 $1.53 $7,650.00
Disclosure

SEC source: 0001209191-21-070325 · doc4.xml · nonDerivative · entry 1

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,777

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 14, 2021 Filed Dec 16, 2021 22:04 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,375 $0.00 Strike: $1.53 $0.00
Disclosure

SEC source: 0001209191-21-069994 · doc4.xml · derivative · entry 5

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,130

Underlying: Common Stock · 1,375 shares

Expires 2028-01-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/4 of the shares subject to the stock option vested and became exercisable on January 8, 2019, and the remaining shares vest in 36 equal monthly installments thereafter.

Read SEC document
December 14, 2021 Filed Dec 16, 2021 22:04 UTC
Virgin HerbertEVP, Research & CSO
SaleCommon Stock 1,375 $45.88 $63,085.00
Disclosure

SEC source: 0001209191-21-069994 · doc4.xml · nonDerivative · entry 2

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,700

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 26, 2021.

Read SEC document
December 14, 2021 Filed Dec 16, 2021 22:04 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionCommon Stock 1,375 $1.53 $2,103.75
Disclosure

SEC source: 0001209191-21-069994 · doc4.xml · nonDerivative · entry 1

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,075

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 01, 2021 Filed Dec 3, 2021 22:22 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 91 $44.97 $4,092.27
Disclosure

SEC source: 0001209191-21-067918 · doc4.xml · nonDerivative · entry 4

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,777

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

Read SEC document
December 01, 2021 Filed Dec 3, 2021 22:22 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 2,050 $44.10 $90,405.00
Disclosure

SEC source: 0001209191-21-067918 · doc4.xml · nonDerivative · entry 3

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,868

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F4 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $43.84 to $44.49 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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December 01, 2021 Filed Dec 3, 2021 22:22 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 4,409 $43.46 $191,615.14
Disclosure

SEC source: 0001209191-21-067918 · doc4.xml · nonDerivative · entry 2

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,918

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $42.83 to $43.81 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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December 01, 2021 Filed Dec 3, 2021 22:22 UTC
Pang PhillipChief Medical Officer
SaleCommon Stock 950 $41.82 $39,729.00
Disclosure

SEC source: 0001209191-21-067918 · doc4.xml · nonDerivative · entry 1

Pang Phillip · CIK 0001787370 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,327

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.41 to $42.31 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 15,125 $0.00 Strike: $1.53 $0.00
Disclosure

SEC source: 0001209191-21-067659 · doc4.xml · derivative · entry 4

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 230,505

Underlying: Common Stock · 15,125 shares

Expires 2028-01-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/4 of the shares subject to the stock option vested and became exercisable on January 8, 2019, and the remaining shares vest in 36 equal monthly installments thereafter.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Virgin HerbertEVP, Research & CSO
SaleCommon Stock 13,750 $50.00 $687,500.00
Disclosure

SEC source: 0001209191-21-067659 · doc4.xml · nonDerivative · entry 3

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,700

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 26, 2021.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Virgin HerbertEVP, Research & CSO
SaleCommon Stock 1,375 $45.60 $62,700.00
Disclosure

SEC source: 0001209191-21-067659 · doc4.xml · nonDerivative · entry 2

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,450

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 26, 2021.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Virgin HerbertEVP, Research & CSO
Exercise / conversionCommon Stock 15,125 $1.53 $23,141.25
Disclosure

SEC source: 0001209191-21-067659 · doc4.xml · nonDerivative · entry 1

Virgin Herbert · CIK 0001786378 · EVP, Research & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,825

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Rice Steven J.Chief Administrative Officer
Exercise / conversionEmployee Stock Option (Right to Buy) · Derivative 10,000 $0.00 Strike: $12.76 $0.00
Disclosure

SEC source: 0001209191-21-067656 · doc4.xml · derivative · entry 3

Rice Steven J. · CIK 0001820108 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 424,441

Underlying: Common Stock · 10,000 shares

Expires 2029-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 1/4 of the shares subject to the stock option vest and become exercisable on September 15, 2020, and the remainder vest in 36 equal monthly installments thereafter.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Rice Steven J.Chief Administrative Officer
SaleCommon Stock 10,000 $50.00 $500,000.00
Disclosure

SEC source: 0001209191-21-067656 · doc4.xml · nonDerivative · entry 2

Rice Steven J. · CIK 0001820108 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,600

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021.

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November 30, 2021 Filed Dec 2, 2021 22:12 UTC
Rice Steven J.Chief Administrative Officer
Exercise / conversionCommon Stock 10,000 $12.76 $127,600.00
Disclosure

SEC source: 0001209191-21-067656 · doc4.xml · nonDerivative · entry 1

Rice Steven J. · CIK 0001820108 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,600

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 600 shares of common stock acquired by the reporting person on November 30, 2021 pursuant to an employee stock purchase program.

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November 30, 2021 Filed Dec 2, 2021 22:10 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 1,435 $0.00 Strike: $41.64 $0.00
Disclosure

SEC source: 0001209191-21-067655 · doc4.xml · derivative · entry 3

Napolitano Janet · CIK 0001821008 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,130

Underlying: Common Stock · 1,435 shares

Expires 2030-08-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/3 of the shares subject to the stock option vested and became exercisable on August 28, 2021, and the remaining shares vest in 24 equal monthly installments thereafter.

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November 30, 2021 Filed Dec 2, 2021 22:10 UTC SaleCommon Stock 1,435 $46.25 $66,368.75
Disclosure

SEC source: 0001209191-21-067655 · doc4.xml · nonDerivative · entry 2

Napolitano Janet · CIK 0001821008 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,374

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 2, 2021.

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November 30, 2021 Filed Dec 2, 2021 22:10 UTC Exercise / conversionCommon Stock 1,435 $41.64 $59,753.40
Disclosure

SEC source: 0001209191-21-067655 · doc4.xml · nonDerivative · entry 1

Napolitano Janet · CIK 0001821008 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,809

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 29, 2021 Filed Dec 1, 2021 20:20 UTC
HANLY ANN M.Chief Technology Officer
PurchaseCommon Stock 11.52 $43.39 $499.85
Disclosure

SEC source: 0001209191-21-067380 · doc4.xml · nonDerivative · entry 1

HANLY ANN M. · CIK 0001854528 · Chief Technology Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 11.52

F1 · ownership.nature: The purchase was effectuated by a minor through a trading account registered in the name of the reporting person's spouse.

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November 29, 2021 Filed Dec 1, 2021 23:30 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 4,428 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-011917 · form4.xml · nonDerivative · entry 4

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,085

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F4 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

F6 · ownership.direct: Shares held directly by Bybee.

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November 29, 2021 Filed Dec 1, 2021 23:30 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 13,057 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-011917 · form4.xml · nonDerivative · entry 3

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,355

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F4 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

F5 · ownership.direct: Shares held directly by Crandell.

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November 29, 2021 Filed Dec 1, 2021 23:30 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 282,219 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-011917 · form4.xml · nonDerivative · entry 2

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 11,665,050

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F3 · ownership.nature: These shares are directly held by ARCH Venture Fund IX Overage, L.P. ("ARCH Overage"). ARCH Venture Partners IX Overage, L.P. ("Overage GPLP"), as the sole general partner of ARCH Overage, may be deemed to beneficially own the shares held by ARCH Overage. GPLLC, as the sole general partner of Overage GPLP, may be deemed to beneficially own the shares held by ARCH Overage. As managing directors of GPLLC, each of the ARCH Managing Directors may be deemed to beneficially own the shares held by ARCH Overage. Each of Overage GPLP, GPLLC and the ARCH Managing Directors disclaims beneficial ownership of the securities reported herein, except to the extent of their pecuniary interest therein, if any.

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November 29, 2021 Filed Dec 1, 2021 23:30 UTC
BYBEE CLINTON10% owner
OtherCommon Stock 217,781 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-011917 · form4.xml · nonDerivative · entry 1

ARCH Venture Partners IX, LLC · CIK 0001723174 · 10% owner

ARCH Venture Partners IX, L.P. · CIK 0001723173 · 10% owner

ARCH Venture Partners IX Overage, L.P. · CIK 0001723172 · 10% owner

ARCH Venture Fund IX, L.P. · CIK 0001666306 · 10% owner

ARCH Venture Fund IX Overage, L.P. · CIK 0001666307 · 10% owner

CRANDELL KEITH · CIK 0001219039 · 10% owner

BYBEE CLINTON · CIK 0001219043 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 9,001,613

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F2 · ownership.nature: These shares are directly held by ARCH Venture Fund IX, L.P. ("ARCH IX"). ARCH Venture Partners IX, L.P. ("GPLP"), as the sole general partner of ARCH IX, may be deemed to beneficially own the shares held by ARCH IX. ARCH Venture Partners IX, LLC ("GPLLC"), as the sole general partner of GPLP, may be deemed to beneficially own the shares held by ARCH IX. As managing directors of GPLLC, each of Keith Crandell and Clinton Bybee (the "ARCH Managing Directors"), may be deemed to beneficially own the shares held by ARCH IX. Each of GPLP, GPLLC and the ARCH Managing Directors disclaims beneficial ownership of the securities reported herein, except to the extent of their pecuniary interest therein, if any.

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November 29, 2021 Filed Dec 1, 2021 23:31 UTC
NELSEN ROBERTDirector · 10% owner
OtherCommon Stock 29,153 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-011919 · form4.xml · nonDerivative · entry 3

NELSEN ROBERT · CIK 0001219042 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,131

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F4 · kind: Change from indirect to direct ownership of shares previously reported as beneficially owned by the Reporting Person.

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November 29, 2021 Filed Dec 1, 2021 23:31 UTC
NELSEN ROBERTDirector · 10% owner
OtherCommon Stock 282,219 $0.00 $0.00
Disclosure

SEC source: 0001062993-21-011919 · form4.xml · nonDerivative · entry 2

NELSEN ROBERT · CIK 0001219042 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 11,665,050

F1 · kind: Distribution of Common Stock held by a limited partnership to its partners for no consideration.

F3 · ownership.nature: The shares are directly held by ARCH Venture Fund IX Overage, L.P. ("ARCH Overage"). The Reporting Person is a managing director of ARCH Venture Partners IX, LLC, the sole general partner of ARCH Venture Partners IX Overage, L.P. ("Overage GPLP"), which is the sole general partner of ARCH Overage, and shares voting and investment control with respect to shares held by ARCH Overage. The Reporting Person disclaims ownership of such shares, except to the extent of his pecuniary interest therein.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.