VERA

SEC source: 0001209191-22-041771 · doc4.xml · derivative · entry 7

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,167

Underlying: Class A Common Stock · 3,514 shares

Expires 2030-12-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 1/4 of the shares subject to the option vest on December 16, 2021, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-22-041771 · doc4.xml · derivative · entry 6

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,419

Underlying: Class A Common Stock · 3,487 shares

Expires 2030-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 1/4 of the shares subject to the option vested on March 12, 2021, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-22-041771 · doc4.xml · nonDerivative · entry 5

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,023

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F2 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.37, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-041771 · doc4.xml · nonDerivative · entry 4

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,688

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F2 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.37, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-041771 · doc4.xml · nonDerivative · entry 3

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-041771 · doc4.xml · nonDerivative · entry 2

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,688

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F2 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.37, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-041771 · doc4.xml · nonDerivative · entry 1

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,175

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-039055 · doc4.xml · derivative · entry 4

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,906

Underlying: Class A Common Stock · 1,239 shares

Expires 2030-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 1/4 of the shares subject to the option vested on March 12, 2021, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-22-039055 · doc4.xml · nonDerivative · entry 3

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,688

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F3 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.03, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-039055 · doc4.xml · nonDerivative · entry 2

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,994

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F2 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.03, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-039055 · doc4.xml · nonDerivative · entry 1

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-038582 · doc4.xml · derivative · entry 7

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,681

Underlying: Class A Common Stock · 3,341 shares

Expires 2030-12-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: 1/4 of the shares subject to the option vest on December 16, 2021, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-22-038582 · doc4.xml · derivative · entry 6

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,145

Underlying: Class A Common Stock · 1,346 shares

Expires 2030-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: 1/4 of the shares subject to the option vested on March 12, 2021, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-22-038582 · doc4.xml · nonDerivative · entry 5

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,994

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F4 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.21, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-038582 · doc4.xml · nonDerivative · entry 4

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,194

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F3 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.26, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-038582 · doc4.xml · nonDerivative · entry 3

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,535

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-038582 · doc4.xml · nonDerivative · entry 2

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,194

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F2 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.33, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-038582 · doc4.xml · nonDerivative · entry 1

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,540

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-037401 · doc4.xml · nonDerivative · entry 4

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 992

F1 · price: These shares were purchased in multiple transactions for all of Reporting Person's indirect accounts on the reported date with prices ranging from $13.05 to $13.85, resulting in a weighted average price of $13.6008. Upon request, the Reporting Person will provide to Issuer, the Commission staff or a security holder of the Issuer the number of shares purchased and the purchase price for each separate transaction.

SEC source: 0001209191-22-037401 · doc4.xml · nonDerivative · entry 3

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse's IRA

Disclosed balance after: 857

F1 · price: These shares were purchased in multiple transactions for all of Reporting Person's indirect accounts on the reported date with prices ranging from $13.05 to $13.85, resulting in a weighted average price of $13.6008. Upon request, the Reporting Person will provide to Issuer, the Commission staff or a security holder of the Issuer the number of shares purchased and the purchase price for each separate transaction.

SEC source: 0001209191-22-037401 · doc4.xml · nonDerivative · entry 2

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Roth IRA

Disclosed balance after: 335

F1 · price: These shares were purchased in multiple transactions for all of Reporting Person's indirect accounts on the reported date with prices ranging from $13.05 to $13.85, resulting in a weighted average price of $13.6008. Upon request, the Reporting Person will provide to Issuer, the Commission staff or a security holder of the Issuer the number of shares purchased and the purchase price for each separate transaction.

SEC source: 0001209191-22-037401 · doc4.xml · nonDerivative · entry 1

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By IRA

Disclosed balance after: 2,816

F1 · price: These shares were purchased in multiple transactions for all of Reporting Person's indirect accounts on the reported date with prices ranging from $13.05 to $13.85, resulting in a weighted average price of $13.6008. Upon request, the Reporting Person will provide to Issuer, the Commission staff or a security holder of the Issuer the number of shares purchased and the purchase price for each separate transaction.

SEC source: 0001209191-22-033485 · doc4.xml · derivative · entry 3

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,491

Underlying: Class A Common Stock · 400 shares

Expires 2030-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 1/4 of the shares subject to the option vested on March 12, 2021, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-22-033485 · doc4.xml · nonDerivative · entry 2

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,194

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 13, 2022.

F3 · price: The price reported is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.10 to $15.53, inclusive. The Reporting Person will provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001209191-22-033485 · doc4.xml · nonDerivative · entry 1

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,594

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,461 shares acquired under the Issuer's Employee Stock Purchase Plan on March 11, 2022.

SEC source: 0001209191-22-031857 · doc4.xml · derivative · entry 1

MORRISSEY MICHAEL · CIK 0001202096 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Class A Common Stock · 40,000 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest monthly over a three-year period, subject to the Reporting Person's continuous service on each vesting date.

SEC source: 0001209191-22-032189 · doc4.xml · derivative · entry 1

Hall Kimball · CIK 0001897965 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,925

Underlying: Class A Common Stock · 9,925 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest in full on the earlier of the first anniversary of the grant date or the date of the Company's 2023 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. Notwithstanding the foregoing, the shares will vest in full upon a change in control, subject to the Reporting Person's continuous service through the date of such change in control.

SEC source: 0001209191-22-032159 · doc4.xml · derivative · entry 1

SEIDENBERG BETH C · CIK 0001184592 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,925

Underlying: Class A Common Stock · 9,925 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest in full on the earlier of the first anniversary of the grant date or the date of the Company's 2023 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. Notwithstanding the foregoing, the shares will vest in full upon a change in control, subject to the Reporting Person's continuous service through the date of such change in control.

SEC source: 0001209191-22-032181 · doc4.xml · derivative · entry 1

ENRIGHT PATRICK G · CIK 0001253886 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,925

Underlying: Class A Common Stock · 9,925 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest in full on the earlier of the first anniversary of the grant date or the date of the Company's 2023 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. Notwithstanding the foregoing, the shares will vest in full upon a change in control, subject to the Reporting Person's continuous service through the date of such change in control.

SEC source: 0001209191-22-032168 · doc4.xml · derivative · entry 1

Morrison Scott W · CIK 0001662426 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,925

Underlying: Class A Common Stock · 9,925 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest in full on the earlier of the first anniversary of the grant date or the date of the Company's 2023 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. Notwithstanding the foregoing, the shares will vest in full upon a change in control, subject to the Reporting Person's continuous service through the date of such change in control.

SEC source: 0001209191-22-032176 · doc4.xml · derivative · entry 1

Katabi Maha · CIK 0001720685 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,925

Underlying: Class A Common Stock · 9,925 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest in full on the earlier of the first anniversary of the grant date or the date of the Company's 2023 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. Notwithstanding the foregoing, the shares will vest in full upon a change in control, subject to the Reporting Person's continuous service through the date of such change in control.

SEC source: 0001209191-22-032186 · doc4.xml · derivative · entry 1

Cheng Andrew · CIK 0001778307 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,925

Underlying: Class A Common Stock · 9,925 shares

Expires 2032-05-23

F1 · derivative.exercise_date: The shares subject to the option will vest in full on the earlier of the first anniversary of the grant date or the date of the Company's 2023 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. Notwithstanding the foregoing, the shares will vest in full upon a change in control, subject to the Reporting Person's continuous service through the date of such change in control.

SEC source: 0001209191-22-011220 · doc4.xml · derivative · entry 1

Young Joseph R · CIK 0001861684 · SVP, Finance, Chief Acct Offcr

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,729

Underlying: Class A Common Stock · 36,729 shares

Expires 2032-02-15

F1 · derivative.exercise_date: 1/48 of the total stock option will vest and become exercisable monthly on the same day of each month following February 16, 2022, subject to continuous service of the Reporting Person on each vesting date.

SEC source: 0001209191-22-011224 · doc4.xml · derivative · entry 1

Curley Joanne · CIK 0001857670 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,964

Underlying: Class A Common Stock · 52,964 shares

Expires 2032-02-15

F1 · derivative.exercise_date: 1/48 of the total stock option will vest and become exercisable monthly on the same day of each month following February 16, 2022, subject to continuous service of the Reporting Person on each vesting date.

SEC source: 0001209191-22-011215 · doc4.xml · derivative · entry 1

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Class A Common Stock · 90,000 shares

Expires 2032-02-15

F1 · derivative.exercise_date: 1/48 of the total stock option will vest and become exercisable monthly on the same day of each month following February 16, 2022, subject to continuous service of the Reporting Person on each vesting date.

SEC source: 0001209191-22-011222 · doc4.xml · derivative · entry 1

Lin Celia · CIK 0001859386 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,412

Underlying: Class A Common Stock · 52,412 shares

Expires 2032-02-15

F1 · derivative.exercise_date: 1/48 of the total stock option will vest and become exercisable monthly on the same day of each month following February 16, 2022, subject to continuous service of the Reporting Person on each vesting date.

SEC source: 0001209191-22-011212 · doc4.xml · derivative · entry 1

Fordyce Marshall · CIK 0001859453 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,154

Underlying: Class A Common Stock · 176,154 shares

Expires 2032-02-15

F1 · derivative.exercise_date: 1/48 of the total stock option will vest and become exercisable monthly on the same day of each month following February 16, 2022, subject to continuous service of the Reporting Person on each vesting date.

SEC source: 0001104659-22-023301 · tm226514d1_form4.xml · nonDerivative · entry 1

Sofinnova Venture Partners X, L.P. · CIK 0001680200 · 10% owner

Sofinnova Management X, L.L.C. · CIK 0001680194 · 10% owner

HEALY JAMES · CIK 0001245624 · 10% owner

Katabi Maha · CIK 0001720685 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,181,442

F1 · ownership.direct: The shares are held directly by Sofinnova Venture Partners X, L.P. ("SVP X"). Sofinnova Management X, L.L.C. ("SM X") is the general partner of SVP X and may be deemed to have sole voting, investment and dispositive power with respect to the shares held by SVP X. James I. Healy and Maha Katabi are the managing members of SM X and may be deemed to have shared voting, investment and dispositive power with respect to the shares held by SVP X. Each of the Reporting Persons disclaims beneficial ownership of such securities, except to the extent of his, her or its proportionate pecuniary interest therein. Michael Powell, a Reporting Person on SVP X's prior Section 16 filings with respect to the Issuer, is no longer a managing member of SM X, and accordingly, is not a Reporting Person on this Form 4.

SEC source: 0000899243-22-013598 · doc4.xml · nonDerivative · entry 1

Longitude Capital Partners IV, LLC · CIK 0001829169 · 10% owner

Longitude Venture Partners IV, L.P. · CIK 0001787456 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 3,429,927

F1 · ownership.nature: These shares are held by Longitude Venture Partners IV, L.P ("LVP IV"). Longitude Capital Partners IV, LLC ("LCP IV") is the general partner of LVP IV and may be deemed to have voting and dispositive power over the shares held by LVP IV. Patrick G. Enright and Juliet Tammenoms Bakker are managing members of LCP IV and may be deemed to share voting and dispositive power with respect to the shares held by LVP IV. Each of LCP IV, Mr. Enright and Ms. Tammenoms Bakker disclaims beneficial ownership of such shares and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. Mr. Enright, a managing member of LCP IV, currently serves on the Issuer's Board of Directors and files separate reports under Section 16(a) of the Securities Exchange Act of 1934 to report transactions in securities of the Issuer.

SEC source: 0000899243-22-013596 · doc4.xml · nonDerivative · entry 1

ENRIGHT PATRICK G · CIK 0001253886 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 3,429,927

F1 · ownership.nature: These shares are held by Longitude Venture Partners IV, L.P ("LVP IV"). Longitude Capital Partners IV, LLC ("LCP IV") is the general partner of LVP IV and may be deemed to have voting and dispositive power over the shares held by LVP IV. Patrick G. Enright and Juliet Tammenoms Bakker are managing members of LCP IV and may be deemed to share voting and dispositive power with respect to the shares held by LVP IV. Each of LCP IV, Mr. Enright and Ms. Tammenoms Bakker disclaims beneficial ownership of such shares and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein.

SEC source: 0001209191-23-007770 · doc4.xml · nonDerivative · entry 1

Young Joseph R · CIK 0001861684 · SVP, Finance, Chief Acct Offcr

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,679

F1 · shares: Shares purchased by the Reporting Person in the Issuer's follow-on offering, which closed on February 6, 2023. The purchase price is the offering price.

F2 · balance_after: Includes 817 shares acquired under the Issuer's Employee Stock Purchase Plan on September 13, 2022.

SEC source: 0001209191-23-007769 · doc4.xml · nonDerivative · entry 1

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,933

F1 · shares: Shares purchased by the Reporting Person in the Issuer's follow-on offering, which closed on February 6, 2023. The purchase price is the offering price.

F2 · balance_after: Includes 380 shares acquired under the Issuer's Employee Stock Purchase Plan on September 13, 2022.

SEC source: 0001209191-21-069233 · doc4.xml · derivative · entry 1

Hall Kimball · CIK 0001897965 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,850

Underlying: Class A Common Stock · 19,850 shares

Expires 2031-12-09

F1 · derivative.exercise_date: The shares subject to the option will vest monthly over a three-year period, subject to the reporting person's continuous service on each vesting date.

SEC source: 0001209191-21-046781 · doc4.xml · derivative · entry 1

Grant Sean · CIK 0001872792 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,000

Underlying: Class A Common Stock · 180,000 shares

Expires 2031-07-12

F1 · derivative.exercise_date: 1/4 of the shares subject to the option vest on July 12, 2022, and 1/48 of the shares vest monthly thereafter.

SEC source: 0001209191-21-033816 · doc4.xml · derivative · entry 3

Longitude Capital Partners IV, LLC · CIK 0001829169 · 10% owner

Longitude Venture Partners IV, L.P. · CIK 0001787456 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Class A Common Stock · 2,187,504 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F1 · derivative.exercise_date: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F1 · derivative.expiration_date: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F2 · ownership.nature: These shares are held by Longitude Venture Partners IV, L.P ("LVP IV"). Longitude Capital Partners IV, LLC ("LCP IV") is the general partner of LVP IV and may be deemed to have voting and dispositive power over the shares held by LVP IV. Patrick G. Enright and Juliet Tammenoms Bakker are managing members of LCP IV and may be deemed to share voting and dispositive power with respect to the shares held by LVP IV. Each of LCP IV, Mr. Enright and Ms. Tammenoms Bakker disclaims beneficial ownership of such shares and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. Mr. Enright, a managing member of LCP IV, currently serves on the Issuer's Board of Directors and files separate reports under Section 16(a) of the Securities Exchange Act of 1934 to report transactions in securities of the Issuer.

SEC source: 0001209191-21-033816 · doc4.xml · nonDerivative · entry 2

Longitude Capital Partners IV, LLC · CIK 0001829169 · 10% owner

Longitude Venture Partners IV, L.P. · CIK 0001787456 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 3,096,594

F2 · ownership.nature: These shares are held by Longitude Venture Partners IV, L.P ("LVP IV"). Longitude Capital Partners IV, LLC ("LCP IV") is the general partner of LVP IV and may be deemed to have voting and dispositive power over the shares held by LVP IV. Patrick G. Enright and Juliet Tammenoms Bakker are managing members of LCP IV and may be deemed to share voting and dispositive power with respect to the shares held by LVP IV. Each of LCP IV, Mr. Enright and Ms. Tammenoms Bakker disclaims beneficial ownership of such shares and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. Mr. Enright, a managing member of LCP IV, currently serves on the Issuer's Board of Directors and files separate reports under Section 16(a) of the Securities Exchange Act of 1934 to report transactions in securities of the Issuer.

SEC source: 0001209191-21-033816 · doc4.xml · nonDerivative · entry 1

Longitude Capital Partners IV, LLC · CIK 0001829169 · 10% owner

Longitude Venture Partners IV, L.P. · CIK 0001787456 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 2,187,504

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F2 · ownership.nature: These shares are held by Longitude Venture Partners IV, L.P ("LVP IV"). Longitude Capital Partners IV, LLC ("LCP IV") is the general partner of LVP IV and may be deemed to have voting and dispositive power over the shares held by LVP IV. Patrick G. Enright and Juliet Tammenoms Bakker are managing members of LCP IV and may be deemed to share voting and dispositive power with respect to the shares held by LVP IV. Each of LCP IV, Mr. Enright and Ms. Tammenoms Bakker disclaims beneficial ownership of such shares and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. Mr. Enright, a managing member of LCP IV, currently serves on the Issuer's Board of Directors and files separate reports under Section 16(a) of the Securities Exchange Act of 1934 to report transactions in securities of the Issuer.

SEC source: 0001209191-21-033818 · doc4.xml · derivative · entry 3

Sofinnova Venture Partners X, L.P. · CIK 0001680200 · 10% owner

Sofinnova Management X, L.L.C. · CIK 0001680194 · 10% owner

HEALY JAMES · CIK 0001245624 · 10% owner

POWELL MICHAEL · CIK 0001202793 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Class A Common Stock · 2,187,504 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F1 · derivative.exercise_date: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F1 · derivative.expiration_date: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F2 · ownership.direct: The shares are held directly by Sofinnova Venture Partners X, L.P. ("SVP X"). Sofinnova Management X, L.L.C. ("SM X") is the general partner of SVP X and may be deemed to have sole voting, investment and dispositive power with respect to the shares held by SVP X. James I. Healy, Maha Katabi, and Michael F. Powell are the managing members of SM X and may be deemed to have shared voting, investment and dispositive power with respect to the shares held by SVP X. Each of the Reporting Persons disclaims beneficial ownership of such securities, except to the extent of his, her or its proportionate pecuniary interest therein.

SEC source: 0001209191-21-033818 · doc4.xml · nonDerivative · entry 2

Sofinnova Venture Partners X, L.P. · CIK 0001680200 · 10% owner

Sofinnova Management X, L.L.C. · CIK 0001680194 · 10% owner

HEALY JAMES · CIK 0001245624 · 10% owner

POWELL MICHAEL · CIK 0001202793 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,914,776

F2 · ownership.direct: The shares are held directly by Sofinnova Venture Partners X, L.P. ("SVP X"). Sofinnova Management X, L.L.C. ("SM X") is the general partner of SVP X and may be deemed to have sole voting, investment and dispositive power with respect to the shares held by SVP X. James I. Healy, Maha Katabi, and Michael F. Powell are the managing members of SM X and may be deemed to have shared voting, investment and dispositive power with respect to the shares held by SVP X. Each of the Reporting Persons disclaims beneficial ownership of such securities, except to the extent of his, her or its proportionate pecuniary interest therein.

SEC source: 0001209191-21-033818 · doc4.xml · nonDerivative · entry 1

Sofinnova Venture Partners X, L.P. · CIK 0001680200 · 10% owner

Sofinnova Management X, L.L.C. · CIK 0001680194 · 10% owner

HEALY JAMES · CIK 0001245624 · 10% owner

POWELL MICHAEL · CIK 0001202793 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,187,504

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series C Preferred Stock automatically converted into Class A Common Stock on a 11.5869:1 basis (on an adjusted basis, after giving effect to the reverse stock split of the Class A Common Stock effected by the Issuer on May 7, 2021) and had no expiration date.

F2 · ownership.direct: The shares are held directly by Sofinnova Venture Partners X, L.P. ("SVP X"). Sofinnova Management X, L.L.C. ("SM X") is the general partner of SVP X and may be deemed to have sole voting, investment and dispositive power with respect to the shares held by SVP X. James I. Healy, Maha Katabi, and Michael F. Powell are the managing members of SM X and may be deemed to have shared voting, investment and dispositive power with respect to the shares held by SVP X. Each of the Reporting Persons disclaims beneficial ownership of such securities, except to the extent of his, her or its proportionate pecuniary interest therein.