Last 12 months
Inside the activity.
1 purchase rows · 2632 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 142 |
| Dec 2025 | 0 | 143 |
| Jan 2026 | 0 | 78 |
| Feb 2026 | 0 | 26 |
| Mar 2026 | 0 | 364 |
| Apr 2026 | 0 | 346 |
| May 2026 | 1 | 340 |
| Jun 2026 | 0 | 298 |
| Jul 2026 | 0 | 240 |
| Aug 2026 | 0 | 251 |
| Sep 2026 | 0 | 260 |
| Oct 2026 | 0 | 144 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| September 24, 2026 Filed Sep 25, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 640 | $469.74 | $300,630.53 |
DisclosureSEC source: 0001106578-26-000149 · primarydocument.xml · nonDerivative · entry 2 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,303 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F3 · price: This transaction was executed in multiple trades at prices ranging from $469.11 to $470.06. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 24, 2026 Filed Sep 25, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionCommon Stock | 9,500 | $117.76 | $1,118,720.00 |
DisclosureSEC source: 0001106578-26-000149 · primarydocument.xml · nonDerivative · entry 1 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,943 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionStock Option · Derivative | 9,500 | $0.00 Strike: $117.76 | $0.00 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · derivative · entry 19 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 375,910 Underlying: Common Stock · 9,500 shares Expires 2027-03-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F17 · derivative.exercise_date: These stock options vested in equal one-third installments on March 15, 2021, 2022 and 2023. F18 · ownership.nature: Stock options held in a family trust as to which the Reporting Person shares investment power and the Reporting Person and immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 240 | $500.05 | $120,012.00 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 13 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,443 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 90 | $498.90 | $44,900.94 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 12 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,683 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F13 · price: This transaction was executed in multiple trades at prices ranging from $498.83 to $499.03. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 270 | $498.38 | $134,563.06 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 11 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,773 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F12 · price: This transaction was executed in multiple trades at prices ranging from $497.80 to $498.72. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 766 | $497.27 | $380,907.67 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 10 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,043 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F11 · price: This transaction was executed in multiple trades at prices ranging from $496.76 to $497.75. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 525 | $496.38 | $260,597.93 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 9 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,809 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F10 · price: This transaction was executed in multiple trades at prices ranging from $495.65 to $496.59. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 155 | $495.17 | $76,751.58 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 8 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 326,334 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F9 · price: This transaction was executed in multiple trades at prices ranging from $494.61 to $495.57. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 160 | $493.72 | $78,995.74 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 7 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 326,489 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F8 · price: This transaction was executed in multiple trades at prices ranging from $493.295 to $494.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 480 | $492.54 | $236,421.41 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 6 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 326,649 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F7 · price: This transaction was executed in multiple trades at prices ranging from $492.19 to $492.90. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 824 | $491.65 | $405,123.64 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 5 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 327,129 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F6 · price: This transaction was executed in multiple trades at prices ranging from $491.13 to $492.03. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,440 | $490.48 | $706,286.16 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 4 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 327,953 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F5 · price: This transaction was executed in multiple trades at prices ranging from $490.12 to $491.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,162 | $489.52 | $1,058,350.89 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 3 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 329,393 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F4 · price: This transaction was executed in multiple trades at prices ranging from $489.12 to $490.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,388 | $488.70 | $1,167,006.53 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 2 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 331,555 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F3 · price: This transaction was executed in multiple trades at prices ranging from $488.11 to $489.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 23, 2026 Filed Sep 24, 2026 20:31 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionCommon Stock | 9,500 | $117.76 | $1,118,720.00 |
DisclosureSEC source: 0001106578-26-000148 · primarydocument.xml · nonDerivative · entry 1 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,943 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionStock Option · Derivative | 9,500 | $0.00 Strike: $117.76 | $0.00 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · derivative · entry 17 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 385,410 Underlying: Common Stock · 9,500 shares Expires 2027-03-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F16 · derivative.exercise_date: These stock options vested in equal one-third installments on March 15, 2021, 2022 and 2023. F17 · ownership.nature: Stock options held in a family trust as to which the Reporting Person shares investment power and the Reporting Person and immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 160 | $499.07 | $79,850.90 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 11 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,443 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F12 · price: This transaction was executed in multiple trades at prices ranging from $498.31 to $499.29. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,358 | $497.73 | $675,911.50 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 10 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,603 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F11 · price: This transaction was executed in multiple trades at prices ranging from $497.23 to $498.22. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,484 | $496.83 | $737,294.98 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 9 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,961 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F10 · price: This transaction was executed in multiple trades at prices ranging from $496.21 to $497.20. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,488 | $495.77 | $737,700.11 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 8 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 327,445 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F9 · price: This transaction was executed in multiple trades at prices ranging from $495.20 to $496.17. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,337 | $494.66 | $661,358.41 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 7 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 328,933 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F8 · price: This transaction was executed in multiple trades at prices ranging from $494.19 to $495.17. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,645 | $493.70 | $812,139.46 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 6 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 330,270 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F7 · price: This transaction was executed in multiple trades at prices ranging from $493.17 to $494.155. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 628 | $492.67 | $309,395.38 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 5 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 331,915 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F6 · price: This transaction was executed in multiple trades at prices ranging from $492.14 to $493.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 736 | $491.45 | $361,704.92 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 4 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 332,543 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F5 · price: This transaction was executed in multiple trades at prices ranging from $491.09 to $491.91. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 424 | $490.54 | $207,988.03 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 3 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,279 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F4 · price: This transaction was executed in multiple trades at prices ranging from $490.09 to $491.08. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 240 | $489.61 | $117,506.90 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 2 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,703 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F3 · price: This transaction was executed in multiple trades at prices ranging from $489.03 to $489.90. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 22, 2026 Filed Sep 23, 2026 20:30 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionCommon Stock | 9,500 | $117.76 | $1,118,720.00 |
DisclosureSEC source: 0001106578-26-000147 · primarydocument.xml · nonDerivative · entry 1 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,943 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionStock Option · Derivative | 9,500 | $0.00 Strike: $117.76 | $0.00 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · derivative · entry 12 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 394,910 Underlying: Common Stock · 9,500 shares Expires 2027-03-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F11 · derivative.exercise_date: These stock options vested in equal one-third installments on March 15, 2021, 2022 and 2023. F12 · ownership.nature: Stock options held in a family trust as to which the Reporting Person shares investment power and the Reporting Person and immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 843 | $496.62 | $418,653.78 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · nonDerivative · entry 6 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,443 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F7 · price: This transaction was executed in multiple trades at prices ranging from $496.28 to $497.06. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,287 | $495.71 | $1,133,693.80 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · nonDerivative · entry 5 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,286 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F6 · price: This transaction was executed in multiple trades at prices ranging from $495.25 to $496.23. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,170 | $494.82 | $1,073,751.15 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · nonDerivative · entry 4 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 327,573 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F5 · price: This transaction was executed in multiple trades at prices ranging from $494.25 to $495.24. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,680 | $493.60 | $1,322,851.22 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · nonDerivative · entry 3 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 329,743 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F4 · price: This transaction was executed in multiple trades at prices ranging from $493.25 to $494.24. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,520 | $492.97 | $749,320.78 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · nonDerivative · entry 2 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 332,423 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F3 · price: This transaction was executed in multiple trades at prices ranging from $492.25 to $493.22. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 20:33 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionCommon Stock | 9,500 | $117.76 | $1,118,720.00 |
DisclosureSEC source: 0001106578-26-000146 · primarydocument.xml · nonDerivative · entry 1 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,943 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionStock Option · Derivative | 9,500 | $0.00 Strike: $117.76 | $0.00 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · derivative · entry 13 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 404,410 Underlying: Common Stock · 9,500 shares Expires 2027-03-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F11 · derivative.exercise_date: These stock options vested in equal one-third installments on March 15, 2021, 2022 and 2023. F12 · ownership.nature: Stock options held in a family trust as to which the Reporting Person shares investment power and the Reporting Person and immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 160 | $498.25 | $79,720.00 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 7 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,443 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 277 | $496.64 | $137,569.14 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 6 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,603 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F7 · price: This transaction was executed in multiple trades at prices ranging from $496.35 to $497.14. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,330 | $495.66 | $1,154,894.32 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 5 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,880 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F6 · price: This transaction was executed in multiple trades at prices ranging from $495.30 to $496.29. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 4,269 | $494.70 | $2,111,871.31 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 4 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 327,210 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F5 · price: This transaction was executed in multiple trades at prices ranging from $494.30 to $495.29. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,216 | $493.78 | $1,094,209.39 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 3 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 331,479 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F4 · price: This transaction was executed in multiple trades at prices ranging from $493.29 to $494.26. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 248 | $492.91 | $122,240.51 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 2 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,695 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F3 · price: This transaction was executed in multiple trades at prices ranging from $492.24 to $493.23. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 18, 2026 Filed Sep 21, 2026 20:44 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionCommon Stock | 9,500 | $117.76 | $1,118,720.00 |
DisclosureSEC source: 0001106578-26-000145 · primarydocument.xml · nonDerivative · entry 1 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 333,943 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
Exercise / conversionStock Option · Derivative | 9,500 | $0.00 Strike: $117.76 | $0.00 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · derivative · entry 16 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 413,910 Underlying: Common Stock · 9,500 shares Expires 2027-03-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F15 · derivative.exercise_date: These stock options vested in equal one-third installments on March 15, 2021, 2022 and 2023. F16 · ownership.nature: Stock options held in a family trust as to which the Reporting Person shares investment power and the Reporting Person and immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 160 | $501.60 | $80,256.40 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · nonDerivative · entry 10 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,443 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F11 · price: This transaction was executed in multiple trades at prices ranging from $501.57 to $501.66. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 468 | $500.09 | $234,042.96 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · nonDerivative · entry 9 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 324,603 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F10 · price: This transaction was executed in multiple trades at prices ranging from $499.975 to $500.76. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 332 | $499.10 | $165,701.10 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · nonDerivative · entry 8 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,071 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F9 · price: This transaction was executed in multiple trades at prices ranging from $498.74 to $499.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
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SaleCommon Stock | 151 | $497.79 | $75,165.88 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · nonDerivative · entry 7 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,403 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F8 · price: This transaction was executed in multiple trades at prices ranging from $497.73 to $498.07. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 1,953 | $497.17 | $970,978.28 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · nonDerivative · entry 6 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 325,554 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F7 · price: This transaction was executed in multiple trades at prices ranging from $496.73 to $497.70. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
| September 17, 2026 Filed Sep 18, 2026 20:41 UTC |
ROTHBLATT MARTINE ADirector · Chairperson & CEO
|
SaleCommon Stock | 2,182 | $496.21 | $1,082,720.84 |
DisclosureSEC source: 0001106578-26-000144 · primarydocument.xml · nonDerivative · entry 5 ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO 10b5-1 filing: Plan reported Ownership: Indirect · by Trust Disclosed balance after: 327,507 F1 · kind: This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 15, 2027; or (b) December 31, 2026. F6 · price: This transaction was executed in multiple trades at prices ranging from $495.72 to $496.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F2 · ownership.nature: Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.