UTHR

SEC source: 0001231589-25-000013 · primarydocument.xml · nonDerivative · entry 1

MAHON PAUL A · CIK 0001231589 · EVP & GENERAL COUNSEL

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 47,781

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is an exercise of stock options and sale of the resulting shares pursuant to a pre-arranged 10b5-1 plan entered into by the reporting person on December 24, 2024.

SEC source: 0002028640-25-000006 · primarydocument.xml · nonDerivative · entry 1

MALCOLM JAN · CIK 0002028640 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 420

F1 · kind: This sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on September 11, 2025.

SEC source: 0001193522-25-000004 · primarydocument.xml · derivative · entry 7

SULLIVAN LOUIS W · CIK 0001193522 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Trust

Disclosed balance after: 1,840

Underlying: Common Stock · 2,720 shares

Expires 2033-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: These securities are held indirectly by a trust over which the reporting person has sole investment power and sole voting power.

SEC source: 0001193522-25-000004 · primarydocument.xml · derivative · entry 6

SULLIVAN LOUIS W · CIK 0001193522 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Trust

Disclosed balance after: 0

Underlying: Common Stock · 3,230 shares

Expires 2031-07-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: These securities are held indirectly by a trust over which the reporting person has sole investment power and sole voting power.

SEC source: 0001193522-25-000004 · primarydocument.xml · nonDerivative · entry 4

SULLIVAN LOUIS W · CIK 0001193522 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · by Trust

Disclosed balance after: 0

F3 · price: This transaction was executed in multiple trades at prices ranging from $511.67 to $512.64. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F1 · ownership.nature: These securities are held indirectly by a trust over which the reporting person has sole investment power and sole voting power.

SEC source: 0001193522-25-000004 · primarydocument.xml · nonDerivative · entry 3

SULLIVAN LOUIS W · CIK 0001193522 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · by Trust

Disclosed balance after: 4,863

F2 · price: This transaction was executed in multiple trades at prices ranging from $510.64 to $511.58. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F1 · ownership.nature: These securities are held indirectly by a trust over which the reporting person has sole investment power and sole voting power.

SEC source: 0001193522-25-000004 · primarydocument.xml · nonDerivative · entry 2

SULLIVAN LOUIS W · CIK 0001193522 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · by Trust

Disclosed balance after: 5,950

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: These securities are held indirectly by a trust over which the reporting person has sole investment power and sole voting power.

SEC source: 0001193522-25-000004 · primarydocument.xml · nonDerivative · entry 1

SULLIVAN LOUIS W · CIK 0001193522 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · by Trust

Disclosed balance after: 3,230

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: These securities are held indirectly by a trust over which the reporting person has sole investment power and sole voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · derivative · entry 21

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 126,375

Underlying: Common Stock · 14,625 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · derivative · entry 20

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 68,065

Underlying: Common Stock · 1,685 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · derivative · entry 19

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 0

Underlying: Common Stock · 6,190 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 17

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 0

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F16 · price: This transaction was executed in multiple trades at prices ranging from $518.98 to $518.99. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 16

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 80

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F8 · price: This transaction was executed in multiple trades at prices ranging from $517.26 to $517.93. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 15

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 200

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F15 · price: This transaction was executed in multiple trades at prices ranging from $515.72 to $516.55. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 14

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 560

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F14 · price: This transaction was executed in multiple trades at prices ranging from $514.65 to $515.63. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 13

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 760

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F13 · price: This transaction was executed in multiple trades at prices ranging from $513.43 to $514.33. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 12

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 7,395

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F12 · price: This transaction was executed in multiple trades at prices ranging from $512.13 to $512.96. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 11

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 7,755

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F11 · price: This transaction was executed in multiple trades at prices ranging from $511.13 to $511.99. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 10

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 7,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 9

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 6,190

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F10 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 8

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 0

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F9 · price: This transaction was executed in multiple trades at prices ranging from $518.80 to $519.02. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 7

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 80

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F8 · price: This transaction was executed in multiple trades at prices ranging from $517.26 to $517.93. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 6

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 280

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F7 · price: This transaction was executed in multiple trades at prices ranging from $516.02 to $517.01. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 5

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 840

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F6 · price: This transaction was executed in multiple trades at prices ranging from $514.93 to $515.88. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 4

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 1,280

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F5 · price: This transaction was executed in multiple trades at prices ranging from $513.83 to $514.60. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 3

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 13,095

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F4 · price: This transaction was executed in multiple trades at prices ranging from $512.81 to $513.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 2

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 13,943

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F3 · price: This transaction was executed in multiple trades at prices ranging from $511.66 to $512.56. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001673232-25-000017 · primarydocument.xml · nonDerivative · entry 1

BENKOWITZ MICHAEL · CIK 0001673232 · PRESIDENT AND COO

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 14,625

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025.

F2 · ownership.nature: Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power.

SEC source: 0001106578-25-000042 · primarydocument.xml · derivative · entry 18

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,000 shares

Expires 2026-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 10

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 130

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

F6 · price: This transaction was executed in multiple trades at prices ranging from $507.58 to $507.64. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 9

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,630

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 8

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,130

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001324863-25-000004 · primarydocument.xml · derivative · entry 5

Thompson Tommy G · CIK 0001324863 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,000

Underlying: Common Stock · 910 shares

Expires 2026-06-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001324863-25-000004 · primarydocument.xml · nonDerivative · entry 2

Thompson Tommy G · CIK 0001324863 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,480

F2 · price: This transaction was executed in multiple trades at prices ranging from $500.38 to $500.78. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F1 · balance_after: Includes 880 shares of common stock to be issued on or about July 8, 2026, as the result of the July 7, 2023 vesting of RSUs for which the reporting person elected to defer receipt of shares.

SEC source: 0001324863-25-000004 · primarydocument.xml · nonDerivative · entry 1

Thompson Tommy G · CIK 0001324863 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,390

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 880 shares of common stock to be issued on or about July 8, 2026, as the result of the July 7, 2023 vesting of RSUs for which the reporting person elected to defer receipt of shares.

SEC source: 0001106578-25-000042 · primarydocument.xml · derivative · entry 17

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 4,000 shares

Expires 2026-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 7

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 130

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

F5 · price: This transaction was executed in multiple trades at prices ranging from $510.445 to $511.34. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 6

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,630

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 5

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,130

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

F4 · price: This transaction was executed in multiple trades at prices ranging from $507.00 to $507.95. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 4

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,130

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000042 · primarydocument.xml · derivative · entry 16

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 4,000 shares

Expires 2026-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 3

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 130

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

F3 · price: This transaction was executed in multiple trades at prices ranging from $501.13 to $501.60. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 2

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,630

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $500.12 to $500.725. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001106578-25-000042 · primarydocument.xml · nonDerivative · entry 1

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,130

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. The transactions reported on this Form 4 are the final trades under this plan.

SEC source: 0001106578-25-000041 · primarydocument.xml · derivative · entry 14

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 4,000 shares

Expires 2026-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. This plan will continue until the earlier of: (a) exhaustion of a tranche of 294,000 stock options that expire March 15, 2026; or (b) December 31, 2025.

SEC source: 0001106578-25-000041 · primarydocument.xml · nonDerivative · entry 7

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 130

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. This plan will continue until the earlier of: (a) exhaustion of a tranche of 294,000 stock options that expire March 15, 2026; or (b) December 31, 2025.

SEC source: 0001106578-25-000041 · primarydocument.xml · nonDerivative · entry 6

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 630

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. This plan will continue until the earlier of: (a) exhaustion of a tranche of 294,000 stock options that expire March 15, 2026; or (b) December 31, 2025.

SEC source: 0001106578-25-000041 · primarydocument.xml · nonDerivative · entry 5

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,630

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. This plan will continue until the earlier of: (a) exhaustion of a tranche of 294,000 stock options that expire March 15, 2026; or (b) December 31, 2025.

F3 · price: This transaction was executed in multiple trades at prices ranging from $492.245 to $492.67. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001106578-25-000041 · primarydocument.xml · nonDerivative · entry 4

ROTHBLATT MARTINE A · CIK 0001106578 · Director · Chairperson & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,130

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. This plan will continue until the earlier of: (a) exhaustion of a tranche of 294,000 stock options that expire March 15, 2026; or (b) December 31, 2025.

SEC source: 0001636178-25-000010 · primarydocument.xml · derivative · entry 11

EDGEMOND JAMES · CIK 0001636178 · CFO AND TREASURER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,517 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on August 5, 2025.