TXG

SEC source: 0001209191-20-065241 · doc4.xml · derivative · entry 2

McAnear Justin J. · CIK 0001786386 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 480,159

Underlying: Class A Common Stock · 10,000 shares

Expires 2028-11-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option, originally for 600,000 shares, of which 119,841 shares have been exercised, vested as to one-fourth of the shares on October 8, 2019 and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.

SEC source: 0001209191-20-065241 · doc4.xml · nonDerivative · entry 1

McAnear Justin J. · CIK 0001786386 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,774

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-20-065099 · doc4.xml · derivative · entry 8

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,898

Underlying: Class A Common Stock · 962 shares

Expires 2027-10-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option, originally for 300,000 shares, of which 191,102 have been exercised, vested as to one-forty-eighth of the shares on October 1, 2017, and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.

SEC source: 0001209191-20-065099 · doc4.xml · derivative · entry 7

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Class A Common Stock · 2,667 shares

Expires 2026-11-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: All of the shares subject to this option are fully vested and exercisable as of the date hereof.

SEC source: 0001209191-20-065099 · doc4.xml · nonDerivative · entry 6

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 880,468

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-20-065099 · doc4.xml · nonDerivative · entry 5

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 879,506

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-21-010089 · doc5.xml · nonDerivative · entry 2

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 46,500

F2 · shares: These shares of Class A Common Stock were previously reported as directly beneficially owned but were contributed to a trust for the benefit of the Reporting Person's children on December 22, 2020.

SEC source: 0001209191-21-010089 · doc5.xml · nonDerivative · entry 1

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 168,791

F1 · shares: These shares of Class A Common Stock were gifted to a trust for the benefit of the Reporting Person's children.

SEC source: 0001209191-20-064559 · doc4.xml · nonDerivative · entry 5

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 488,491

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F6 · price: This transaction was executed in multiple trades at prices ranging from $151.06 to $151.45. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-064559 · doc4.xml · nonDerivative · entry 4

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 488,791

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F5 · price: This transaction was executed in multiple trades at prices ranging from $149.15 to $149.64. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-064559 · doc4.xml · nonDerivative · entry 3

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 489,592

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $148.10 to $149.05. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-064559 · doc4.xml · nonDerivative · entry 2

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 492,690

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $147.09 to $148.07. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-064559 · doc4.xml · nonDerivative · entry 1

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 494,890

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $146.05 to $147.04. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-065099 · doc4.xml · nonDerivative · entry 4

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 876,839

SEC source: 0001209191-20-065099 · doc4.xml · nonDerivative · entry 3

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 89,960

F1 · ownership.nature: The shares are held by the Y/S Descendants' Trust, for which the Reporting Person serves as trustee.

SEC source: 0001209191-20-062775 · doc4.xml · nonDerivative · entry 3

Venrock Associates VI, L.P. · CIK 0001495384 · 10% owner

Venrock Partners VI, L.P. · CIK 0001495386 · 10% owner

Venrock Management VI, LLC · CIK 0001495383 · 10% owner

Venrock Partners Management VI, LLC · CIK 0001495385 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 2,037,825

F5 · kind: On December 10, 2020, VM VI and VPM VI distributed an aggregate of 268,692 shares of Class A Common Stock to their members and participants.

F5 · shares: On December 10, 2020, VM VI and VPM VI distributed an aggregate of 268,692 shares of Class A Common Stock to their members and participants.

F5 · price: On December 10, 2020, VM VI and VPM VI distributed an aggregate of 268,692 shares of Class A Common Stock to their members and participants.

F6 · ownership.nature: Consists of 1,889,497 shares of Class A Common Stock held by VA VI and 148,328 shares of Class A Common Stock held by VP VI.

SEC source: 0001209191-20-062772 · doc4.xml · nonDerivative · entry 4

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,291

F7 · shares: On December 10, 2020, Dr. Roberts received an aggregate of 93,487 shares of Class A Common Stock as part of the distribution of shares of VM VI and VPM VI.

SEC source: 0001209191-20-062772 · doc4.xml · nonDerivative · entry 3

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 2,037,825

F5 · kind: On December 10, 2020, VM VI and VPM VI distributed an aggregate of 268,692 shares of Class A Common Stock to their members and participants.

F5 · shares: On December 10, 2020, VM VI and VPM VI distributed an aggregate of 268,692 shares of Class A Common Stock to their members and participants.

F5 · price: On December 10, 2020, VM VI and VPM VI distributed an aggregate of 268,692 shares of Class A Common Stock to their members and participants.

F6 · ownership.nature: Consists of 1,889,497 shares of Class A Common Stock held by VA VI and 148,328 shares of Class A Common Stock held by VP VI.

SEC source: 0001209191-20-065099 · doc4.xml · nonDerivative · entry 2

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 104,960

F1 · ownership.nature: The shares are held by the Y/S Descendants' Trust, for which the Reporting Person serves as trustee.

SEC source: 0001209191-20-065099 · doc4.xml · nonDerivative · entry 1

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 861,839

SEC source: 0001209191-20-062588 · doc4.xml · nonDerivative · entry 1

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 966,799

SEC source: 0001209191-20-062775 · doc4.xml · derivative · entry 4

Venrock Associates VI, L.P. · CIK 0001495384 · 10% owner

Venrock Partners VI, L.P. · CIK 0001495386 · 10% owner

Venrock Management VI, LLC · CIK 0001495383 · 10% owner

Venrock Partners Management VI, LLC · CIK 0001495385 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 5,790,422

Underlying: Class A Common Stock · 3,000,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, all outstanding shares of Class B Common Stock will convert automatically into Class A Common Stock upon any transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

F7 · derivative.exercise_date: Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, all outstanding shares of Class B Common Stock will convert automatically into Class A Common Stock upon any transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

F7 · derivative.expiration_date: Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, all outstanding shares of Class B Common Stock will convert automatically into Class A Common Stock upon any transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

F8 · ownership.nature: Consists of 5,368,880 shares of Class B Common Stock held by VA VI and 421,542 shares of Class B Common Stock held by VP VI.

SEC source: 0001209191-20-062775 · doc4.xml · nonDerivative · entry 2

Venrock Associates VI, L.P. · CIK 0001495384 · 10% owner

Venrock Partners VI, L.P. · CIK 0001495386 · 10% owner

Venrock Management VI, LLC · CIK 0001495383 · 10% owner

Venrock Partners Management VI, LLC · CIK 0001495385 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 2,306,517

F3 · kind: On December 8, 2020, VA VI and VP VI distributed an aggregate of 1,000,000 shares of Class A Common Stock to their limited partners and general partners. Of the 1,000,000 shares distributed, 249,521 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 19,171 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

F3 · shares: On December 8, 2020, VA VI and VP VI distributed an aggregate of 1,000,000 shares of Class A Common Stock to their limited partners and general partners. Of the 1,000,000 shares distributed, 249,521 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 19,171 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

F3 · price: On December 8, 2020, VA VI and VP VI distributed an aggregate of 1,000,000 shares of Class A Common Stock to their limited partners and general partners. Of the 1,000,000 shares distributed, 249,521 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 19,171 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

F4 · ownership.nature: Consists of 1,889,497 shares of Class A Common Stock held by VA VI, 249,521 shares of Class A Common Stock held by VM VI, 148,328 shares of Class A Common Stock held by VP VI and 19,171 shares of Class A Common Stock held by VPM VI.

SEC source: 0001209191-20-062775 · doc4.xml · nonDerivative · entry 1

Venrock Associates VI, L.P. · CIK 0001495384 · 10% owner

Venrock Partners VI, L.P. · CIK 0001495386 · 10% owner

Venrock Management VI, LLC · CIK 0001495383 · 10% owner

Venrock Partners Management VI, LLC · CIK 0001495385 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 3,037,825

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares of Class A Common Stock received upon conversion of 3,000,000 shares of Class B Common Stock.

F2 · ownership.nature: Consists of 2,816,685 shares of Class A Common Stock held by Venrock Associates VI, L.P. ("VA VI") and 221,140 shares of Class A Common Stock held by Venrock Partners VI, L.P. ("VP VI").

SEC source: 0001209191-20-062772 · doc4.xml · derivative · entry 5

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 5,790,422

Underlying: Class A Common Stock · 3,000,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · price: Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, all outstanding shares of Class B Common Stock will convert automatically into Class A Common Stock upon any transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

F8 · derivative.exercise_date: Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, all outstanding shares of Class B Common Stock will convert automatically into Class A Common Stock upon any transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

F8 · derivative.expiration_date: Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, all outstanding shares of Class B Common Stock will convert automatically into Class A Common Stock upon any transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

F9 · ownership.nature: Consists of 5,368,880 shares of Class B Common Stock held by VA VI and 421,542 shares of Class B Common Stock held by VP VI.

SEC source: 0001209191-20-062772 · doc4.xml · nonDerivative · entry 2

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 2,306,517

F3 · kind: On December 8, 2020, VA VI and VP VI distributed an aggregate of 1,000,000 shares of Class A Common Stock to their limited partners and general partners. Of the 1,000,000 shares distributed, 249,521 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 19,171 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

F3 · shares: On December 8, 2020, VA VI and VP VI distributed an aggregate of 1,000,000 shares of Class A Common Stock to their limited partners and general partners. Of the 1,000,000 shares distributed, 249,521 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 19,171 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

F3 · price: On December 8, 2020, VA VI and VP VI distributed an aggregate of 1,000,000 shares of Class A Common Stock to their limited partners and general partners. Of the 1,000,000 shares distributed, 249,521 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 19,171 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

F4 · ownership.nature: Consists of 1,889,497 shares of Class A Common Stock held by VA VI, 249,521 shares of Class A Common Stock held by VM VI, 148,328 shares of Class A Common Stock held by VP VI and 19,171 shares of Class A Common Stock held by VPM VI.

SEC source: 0001209191-20-062772 · doc4.xml · nonDerivative · entry 1

ROBERTS BRYAN E · CIK 0001239242 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By funds

Disclosed balance after: 3,037,825

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares of Class A Common Stock received upon conversion of 3,000,000 shares of Class B Common Stock.

F2 · ownership.nature: Consists of 2,816,685 shares of Class A Common Stock held by Venrock Associates VI, L.P. ("VA VI") and 221,140 shares of Class A Common Stock held by Venrock Partners VI, L.P. ("VP VI").

SEC source: 0001209191-20-061711 · doc4.xml · derivative · entry 7

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 630,000

Underlying: Class A Common Stock · 17,000 shares

Expires 2027-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F7 · derivative.exercise_date: This option, originally for 800,000 shares, of which 170,000 shares have been exercised, vested as to one-fourth of the shares on February 2, 2018 and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.

SEC source: 0001209191-20-061711 · doc4.xml · nonDerivative · entry 6

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 963

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F6 · price: This transaction was executed in multiple trades at prices ranging from $153.39 to $154.08. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061711 · doc4.xml · nonDerivative · entry 5

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,681

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F5 · price: This transaction was executed in multiple trades at prices ranging from $152.36 to $153.34. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061711 · doc4.xml · nonDerivative · entry 4

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,091

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $151.36 to $152.24. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061711 · doc4.xml · nonDerivative · entry 3

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,386

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $150.36 to $151.35. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061711 · doc4.xml · nonDerivative · entry 2

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,882

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $149.36 to $150.35. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061711 · doc4.xml · nonDerivative · entry 1

CRUTCHFIELD BRADFORD · CIK 0001246406 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,963

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

SEC source: 0001209191-20-061715 · doc4.xml · nonDerivative · entry 5

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 495,991

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F6 · price: This transaction was executed in multiple trades at prices ranging from $153.34 to $153.91. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061715 · doc4.xml · nonDerivative · entry 4

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 496,891

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F5 · price: This transaction was executed in multiple trades at prices ranging from $152.24 to $153.16. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061715 · doc4.xml · nonDerivative · entry 3

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 497,391

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $151.59 to $151.73. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061715 · doc4.xml · nonDerivative · entry 2

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 497,891

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $150.58 to $151.52. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061715 · doc4.xml · nonDerivative · entry 1

STUELPNAGEL JOHN R · CIK 0001189140 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 501,391

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $149.56 to $150.53. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061714 · doc4.xml · derivative · entry 9

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 124,515

Underlying: Class A Common Stock · 3,750 shares

Expires 2028-11-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F8 · derivative.exercise_date: This option, originally for 250,000 shares, of which 125,485 have been exercised, vested as to one forty-eighth of the shares on October 1, 2018, and one-forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.

SEC source: 0001209191-20-061714 · doc4.xml · derivative · entry 8

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,860

Underlying: Class A Common Stock · 6,250 shares

Expires 2027-10-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F7 · derivative.exercise_date: This option, originally for 300,000 shares, of which 190,140 have been exercised, vested as to one-forty-eighth of the shares on October 1, 2017, and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 7

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 967,181

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F6 · price: This transaction was executed in multiple trades at prices ranging from $153.76 to $153.91. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 6

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 967,514

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F5 · price: This transaction was executed in multiple trades at prices ranging from $152.58 to $153.57. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 5

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 969,688

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $151.51 to $152.46. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 4

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 970,779

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $150.48 to $151.40. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 3

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 974,177

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $149.46 to $150.45. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 2

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 977,181

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

SEC source: 0001209191-20-061714 · doc4.xml · nonDerivative · entry 1

Saxonov Serge · CIK 0001786720 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 973,431

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

SEC source: 0001209191-20-061713 · doc4.xml · derivative · entry 7

McAnear Justin J. · CIK 0001786386 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 500,000

Underlying: Class A Common Stock · 10,000 shares

Expires 2028-11-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F7 · derivative.exercise_date: This option, originally for 600,000 shares, of which 100,000 shares have been exercised, vested as to one-fourth of the shares on October 8, 2019 and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.

SEC source: 0001209191-20-061713 · doc4.xml · nonDerivative · entry 6

McAnear Justin J. · CIK 0001786386 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 933

F1 · kind: The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.

F6 · price: This transaction was executed in multiple trades at prices ranging from $153.60 to $153.95. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.