TMO

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 9

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 126,183.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $504.06 to $504.07, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 8

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 126,303.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $502.59 to $502.60, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 7

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 126,423.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $501.56 to $502.36, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 6

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 126,783.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $500.47 to $501.44, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 5

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 127,165.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $499.36 to $500.14, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 4

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 127,405.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $497.80 to $498.70, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 3

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 128,085.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $496.43 to $497.37, inclusive.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 2

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 128,565.358

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $495.08 to $495.46, inclusive. The reporting person undertakes to provide to Thermo Fisher Scientific Inc. ("TMO"), any security holder of TMO or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), (14), (15), (16), (17), (18), (19), (20), and (21) to this Form 4.

SEC source: 0000097745-26-000055 · form4.xml · nonDerivative · entry 1

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 128,925.358

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000097745-26-000039 · form4.xml · nonDerivative · entry 3

Lowery Frederick M. · CIK 0001777440 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,044.4044

SEC source: 0000097745-26-000039 · form4.xml · nonDerivative · entry 2

Lowery Frederick M. · CIK 0001777440 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,308.3954

SEC source: 0000097745-26-000039 · form4.xml · nonDerivative · entry 1

Lowery Frederick M. · CIK 0001777440 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,830.0914

SEC source: 0000097745-26-000041 · form4.xml · nonDerivative · entry 3

Shafer Michael D · CIK 0002020619 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,556.9546

SEC source: 0000097745-26-000041 · form4.xml · nonDerivative · entry 2

Shafer Michael D · CIK 0002020619 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,808.6146

SEC source: 0000097745-26-000041 · form4.xml · nonDerivative · entry 1

Shafer Michael D · CIK 0002020619 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,274.8186

SEC source: 0000097745-26-000043 · form4.xml · nonDerivative · entry 2

Williamson Stephen · CIK 0001648929 · Retiring Sr. VP and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,499.4

SEC source: 0000097745-26-000043 · form4.xml · nonDerivative · entry 1

Williamson Stephen · CIK 0001648929 · Retiring Sr. VP and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,746.469

SEC source: 0000097745-26-000045 · form4.xml · nonDerivative · entry 2

Pettiti Gianluca · CIK 0001844600 · President & COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,450.832

SEC source: 0000097745-26-000045 · form4.xml · nonDerivative · entry 1

Pettiti Gianluca · CIK 0001844600 · President & COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,782.513

SEC source: 0000097745-26-000047 · form4.xml · nonDerivative · entry 2

Lagarde Michel · CIK 0001518973 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,151.304

SEC source: 0000097745-26-000047 · form4.xml · nonDerivative · entry 1

Lagarde Michel · CIK 0001518973 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,511.029

SEC source: 0000097745-26-000049 · form4.xml · nonDerivative · entry 4

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,966.3555

SEC source: 0000097745-26-000049 · form4.xml · nonDerivative · entry 3

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,970.7585

SEC source: 0000097745-26-000049 · form4.xml · nonDerivative · entry 2

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,015.2175

SEC source: 0000097745-26-000049 · form4.xml · nonDerivative · entry 1

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,070.6925

SEC source: 0000097745-26-000051 · form4.xml · nonDerivative · entry 2

Britt Lisa P. · CIK 0001676320 · Sr. VP and Chief HR Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,784.148

SEC source: 0000097745-26-000051 · form4.xml · nonDerivative · entry 1

Britt Lisa P. · CIK 0001676320 · Sr. VP and Chief HR Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,869.557

SEC source: 0000097745-26-000053 · form4.xml · nonDerivative · entry 2

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 123,925.358

SEC source: 0000097745-26-000053 · form4.xml · nonDerivative · entry 1

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,136.526

SEC source: 0000097745-26-000029 · form4.xml · derivative · entry 6

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,109

Underlying: Common Stock · 32,109 shares

Expires 2036-02-25

F4 · derivative.exercise_date: The option vests in four equal annual installments beginning on February 28, 2027.

SEC source: 0000097745-26-000029 · form4.xml · nonDerivative · entry 2

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 128,610.285

SEC source: 0000097745-26-000029 · form4.xml · nonDerivative · entry 1

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,277.285

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. The Company's Compensation Committee determined on February 25, 2026, that the performance criteria related to this award were satisfied. One-third of the shares vest on February 28, 2026 and 2027. The remaining one-third will vest on February 28, 2028, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2025, through to December 31, 2027.

SEC source: 0000097745-26-000030 · form4.xml · derivative · entry 3

Pettiti Gianluca · CIK 0001844600 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,270

Underlying: Common Stock · 16,270 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option vests in four equal annual installments beginning on February 28, 2027.

SEC source: 0000097745-26-000030 · form4.xml · nonDerivative · entry 2

Pettiti Gianluca · CIK 0001844600 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,524.223

SEC source: 0000097745-26-000030 · form4.xml · nonDerivative · entry 1

Pettiti Gianluca · CIK 0001844600 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,809.223

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. The Company's Compensation Committee determined on February 25, 2026, that the performance criteria related to this award were satisfied. One-third of the shares vest on February 28, 2026 and 2027. The remaining one-third will vest on February 28, 2028, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2025, through to December 31, 2027.

SEC source: 0000097745-26-000031 · form4.xml · derivative · entry 3

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 985

Underlying: Common Stock · 985 shares

Expires 2036-02-25

F3 · derivative.exercise_date: The option vests in four equal annual installments beginning on February 28, 2027.

SEC source: 0000097745-26-000031 · form4.xml · nonDerivative · entry 2

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,082.9815

SEC source: 0000097745-26-000031 · form4.xml · nonDerivative · entry 1

Holmes Joseph R. · CIK 0001839832 · VP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,745.9815

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. The Company's Compensation Committee determined on February 25, 2026, that the performance criteria related to this award were satisfied. One-third of the shares vest on February 28, 2026 and 2027. The remaining one-third will vest on February 28, 2028, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2025, through to December 31, 2027.

F2 · balance_after: Shares represent an adjustment to the final tranche of a performance-based restricted stock unit award granted on February 22, 2023. On February 25, 2026, the Compensation Committee certified a 15% reduction based on the Company's relative TSR performance over the three-year measurement period, resulting in 6 fewer shares than previously reported.

SEC source: 0000097745-26-000032 · form4.xml · derivative · entry 3

Shafer Michael D · CIK 0002020619 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,698

Underlying: Common Stock · 13,698 shares

Expires 2036-02-25

F3 · derivative.exercise_date: The option vests in four equal annual installments beginning on February 28, 2027.

SEC source: 0000097745-26-000032 · form4.xml · nonDerivative · entry 2

Shafer Michael D · CIK 0002020619 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,372.8026

SEC source: 0000097745-26-000032 · form4.xml · nonDerivative · entry 1

Shafer Michael D · CIK 0002020619 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,243.8026

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. The Company's Compensation Committee determined on February 25, 2026, that the performance criteria related to this award were satisfied. One-third of the shares vest on February 28, 2026 and 2027. The remaining one-third will vest on February 28, 2028, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2025, through to December 31, 2027.

F2 · balance_after: Shares represent an adjustment to the final tranche of a performance-based restricted stock unit award granted on February 22, 2023. On February 25, 2026, the Compensation Committee certified a 15% reduction based on the Company's relative TSR performance over the three-year measurement period, resulting in 56 fewer shares than previously reported.

SEC source: 0000097745-26-000033 · form4.xml · derivative · entry 2

Shropshire Thomas B Jr. · CIK 0002070785 · SVP and General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,281

Underlying: Common Stock · 4,281 shares

Expires 2036-02-25

F1 · derivative.exercise_date: The option vests in four equal annual installments beginning on February 28, 2027.

SEC source: 0000097745-26-000033 · form4.xml · nonDerivative · entry 1

Shropshire Thomas B Jr. · CIK 0002070785 · SVP and General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,057.524

SEC source: 0000097745-26-000034 · form4.xml · nonDerivative · entry 1

Lowery Frederick M. · CIK 0001777440 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,941.3724

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. On February 25, 2026, the Compensation Committee certified achievement of the applicable performance criteria. The award vests in three equal tranches on February 28, 2026, 2027 and 2028, in accordance with the terms of the award agreement.

F2 · balance_after: Shares represent an adjustment to the final tranche of a performance-based restricted stock unit award granted on February 22, 2023. On February 25, 2026, the Compensation Committee certified a 15% reduction based on the Company's relative TSR performance over the three-year measurement period, resulting in 64 fewer shares than previously reported.

SEC source: 0000097745-26-000035 · form4.xml · derivative · entry 3

Britt Lisa P. · CIK 0001676320 · Sr. VP and Chief HR Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,139

Underlying: Common Stock · 5,139 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option vests in four equal annual installments beginning on February 28, 2027.

SEC source: 0000097745-26-000035 · form4.xml · nonDerivative · entry 2

Britt Lisa P. · CIK 0001676320 · Sr. VP and Chief HR Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,132.227

SEC source: 0000097745-26-000035 · form4.xml · nonDerivative · entry 1

Britt Lisa P. · CIK 0001676320 · Sr. VP and Chief HR Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,959.227

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. The Company's Compensation Committee determined on February 25, 2026, that the performance criteria related to this award were satisfied. One-third of the shares vest on February 28, 2026 and 2027. The remaining one-third will vest on February 28, 2028, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2025, through to December 31, 2027.

SEC source: 0000097745-26-000036 · form4.xml · nonDerivative · entry 1

Lagarde Michel · CIK 0001518973 · Executive Vice President & COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,347.909

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. On February 25, 2026, the Compensation Committee certified achievement of the applicable performance criteria. The award vests in three equal tranches on February 28, 2026, 2027 and 2028, in accordance with the terms of the award agreement.

SEC source: 0000097745-26-000037 · form4.xml · nonDerivative · entry 1

Williamson Stephen · CIK 0001648929 · Sr. VP and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,421.193

F1 · shares: Shares represent a performance-based restricted stock unit award granted on February 19, 2025. On February 25, 2026, the Compensation Committee certified achievement of the applicable performance criteria. The award vests in three equal tranches on February 28, 2026, 2027 and 2028, in accordance with the terms of the award agreement.

SEC source: 0000097745-26-000014 · form4.xml · nonDerivative · entry 1

Pettiti Gianluca · CIK 0001844600 · Executive Vice President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,752.223

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 12, 2025.