TMO

SEC source: 0001127602-23-015098 · form4.xml · nonDerivative · entry 3

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 148,836.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $542.40 to $543.36, inclusive.

SEC source: 0001127602-23-015098 · form4.xml · nonDerivative · entry 2

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 150,629.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $541.37 to $542.31, inclusive. The reporting person undertakes to provide to Thermo Fisher Scientific Inc. ("TMO"), any security holder of TMO or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5), (6), (7), (8), (9), (10), (11) and (12) to this Form 4.

SEC source: 0001127602-23-015098 · form4.xml · nonDerivative · entry 1

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 151,329.53

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

SEC source: 0001127602-23-014894 · form4.xml · derivative · entry 24

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 74,800

Underlying: Common Stock · 10,000 shares

Expires 2024-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F18 · derivative.exercise_date: The option vested in four equal installments on February 28, 2018, 2019, 2020, and 2021.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 18

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 141,329.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $547.56 to $548.36, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 17

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 142,629.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $546.35 to $547.33, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 16

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,730.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $545.35 to $546.34, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 15

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,994.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $544.26 to $545.19, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 14

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 148,229.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $543.26 to $544.25, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 13

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 150,629.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $542.15 to $543.03, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 12

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 151,329.53

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

SEC source: 0001127602-23-014900 · form4.xml · nonDerivative · entry 1

Pettiti Gianluca · CIK 0001844600 · Executive Vice President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,601

SEC source: 0001127602-23-014894 · form4.xml · derivative · entry 23

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,800

Underlying: Common Stock · 10,000 shares

Expires 2024-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F18 · derivative.exercise_date: The option vested in four equal installments on February 28, 2018, 2019, 2020, and 2021.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 11

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 141,329.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $552.81 to $553.63, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 10

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 141,561.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $551.67 to $552.28, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 9

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 142,157.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 8

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 142,257.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $549.49 to $550.31, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 7

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,134.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $548.34 to $549.13, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 6

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,734.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $547.31 to $548.06, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 5

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,582.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $546.29 to $547.28, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 4

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 146,979.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $545.28 to $546.20, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 3

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 149,480.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $544.14 to $545.13, inclusive.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 2

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 150,584.53

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $543.09 to $544.07, inclusive. The reporting person undertakes to provide to Thermo Fisher Scientific Inc. ("TMO"), any security holder of TMO or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), (14), (15) and (16) to this Form 4.

SEC source: 0001127602-23-014894 · form4.xml · nonDerivative · entry 1

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 151,329.53

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 18, 2022.

SEC source: 0001127602-23-012190 · form4.xml · derivative · entry 1

WEISLER DION J · CIK 0001580693 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,844.3

Underlying: Common Stock · 65.06 shares

Expires not disclosed

F1 · derivative.exercise_price: Convertible into Common Stock on a 1-for-1 basis.

F2 · price: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

F2 · derivative.exercise_date: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

F2 · derivative.expiration_date: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

SEC source: 0001127602-23-012199 · form4.xml · derivative · entry 1

SPERLING SCOTT M · CIK 0001214212 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,622.05

Underlying: Common Stock · 71.57 shares

Expires not disclosed

F1 · derivative.exercise_price: Convertible into Common Stock on a 1-for-1 basis.

F2 · price: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

F2 · derivative.exercise_date: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

F2 · derivative.expiration_date: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

SEC source: 0001127602-23-012205 · form4.xml · derivative · entry 1

Keith R. Alexandra · CIK 0001710268 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 542.45

Underlying: Common Stock · 54.22 shares

Expires not disclosed

F1 · derivative.exercise_price: Convertible into Common Stock on a 1-for-1 basis.

F2 · price: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

F2 · derivative.exercise_date: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

F2 · derivative.expiration_date: Represents stock units credited to the Reporting Person's account as of April 1, 2023, at a price of $576.37 per unit pursuant to the Issuer's Deferred Compensation Plan for Directors (the "Plan"). Directors' retainers are deferred quarterly under the Plan as Common Stock units based on the closing price of the stock as of the quarter end. The shares are distributable as stock upon cessation of director service (for any reason) or a change of control.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 23

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 59,155

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 22

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 59,255

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 21

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 59,355

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F22 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $558.87 to $559.30, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 20

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 59,755

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $557.49 to $558.40, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 19

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 60,555

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $556.43 to $557.34, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 18

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 61,115

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $555.40 to $556.12, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 17

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 61,515

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $554.32 to $555.31, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 16

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 62,365

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $553.26 to $554.00, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 15

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 63,032

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $552.02 to $552.93, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 14

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 64,232

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $551.02 to $551.96, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 13

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 65,072

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $549.95 to $550.92, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 12

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 66,255

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $548.65 to $549.56, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 11

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 66,455

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $546.31 to $546.55, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 10

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 66,655

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $549.69 to $550.41, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 9

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 67,055

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $547.98 to $548.61, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 8

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 67,455

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $546.93 to $547.87, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 7

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 68,155

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $545.93 to $546.89, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 6

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 68,755

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $544.84 to $545.82, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 5

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 70,055

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $543.84 to $544.76, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 4

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 71,639

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $542.01 to $542.96, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 3

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 72,939

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $540.92 to $541.75, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 2

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 73,655

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $539.78 to $540.73, inclusive.

SEC source: 0001127602-23-010280 · form4.xml · nonDerivative · entry 1

CASPER MARC N · CIK 0001216055 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Floral Park Associates, Inc.

Disclosed balance after: 73,855

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 2, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $538.25 to $538.31, inclusive. The reporting person undertakes to provide to Thermo Fisher Scientific Inc. ("TMO"), any security holder of TMO or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), (14), (15), (16), (17), (18), (19), (20), (21) and (22) to this Form 4.