TLSI

SEC source: 0001628280-26-010602 · wk-form4_1771880877.xml · nonDerivative · entry 1

Stansky Michael P · CIK 0001424204 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 787,132

SEC source: 0001628280-26-010603 · wk-form4_1771880883.xml · nonDerivative · entry 1

Szela Mary T · CIK 0001410289 · Director · CEO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 773,289

SEC source: 0001628280-26-010606 · wk-form4_1771880906.xml · nonDerivative · entry 1

Patience David · CIK 0001970009 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 268,657

SEC source: 0001628280-26-007409 · wk-form4_1770853869.xml · derivative · entry 1

Stansky Michael P · CIK 0001424204 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,537

Underlying: Common Stock · 92,537 shares

Expires 2036-02-03

F1 · derivative.exercise_date: The shares subject to this stock option vest in three equal annual installments commencing on February 4, 2027, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

SEC source: 0001628280-26-046501 · wk-form5_1782936102.xml · nonDerivative · entry 4

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 131,758

F1 · shares: Represents shares acquired by the Reporting Person through the Issuer's Employee Stock Purchase Plan in a transaction exempt under Rule 16b-3.

SEC source: 0001628280-26-046511 · wk-form5_1782936210.xml · nonDerivative · entry 3

Szela Mary T · CIK 0001410289 · Director · CEO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,023,826

F1 · shares: Represents shares acquired by the Reporting Person through the Issuer's Employee Stock Purchase Plan in a transaction exempt under Rule 16b-3.

SEC source: 0001992151-25-000004 · wk-form4_1764104159.xml · derivative · entry 2

Devlin Jodi · CIK 0001992151 · Chief of Clinical Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 463,750

Underlying: Common Stock · 100,000 shares

Expires 2025-11-23

F2 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of November 24, 2025 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to continued employment through the respective vesting date.

SEC source: 0001992151-25-000004 · wk-form4_1764104159.xml · nonDerivative · entry 1

Devlin Jodi · CIK 0001992151 · Chief of Clinical Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,571

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on November 24, 2025, subject to continued employment through the respective vesting date.

SEC source: 0001982621-25-000009 · wk-form4_1764103415.xml · derivative · entry 2

Stevens Jennifer · CIK 0001982621 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 323,782

Underlying: Common Stock · 100,000 shares

Expires 2035-11-23

F2 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of November 24, 2025 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to continued employment through the respective vesting date.

SEC source: 0001982621-25-000009 · wk-form4_1764103415.xml · nonDerivative · entry 1

Stevens Jennifer · CIK 0001982621 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 127,640

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on November 24, 2025, subject to continued employment through the respective vesting date.

SEC source: 0001982638-25-000004 · wk-form4_1764103333.xml · derivative · entry 2

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 408,937

Underlying: Common Stock · 120,000 shares

Expires 2035-11-23

F2 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of November 24, 2025 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to continued employment through the respective vesting date.

SEC source: 0001982638-25-000004 · wk-form4_1764103333.xml · nonDerivative · entry 1

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 113,854

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on November 24, 2025, subject to continued employment through the respective vesting date.

SEC source: 0001410289-25-000006 · wk-form4_1764104104.xml · derivative · entry 4

Szela Mary T · CIK 0001410289 · Director · CEO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,578,182

Underlying: Common Stock · 250,000 shares

Expires 2035-11-23

F4 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of November 24, 2025 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to continued employment through the respective vesting date.

SEC source: 0001410289-25-000006 · wk-form4_1764104104.xml · nonDerivative · entry 3

Szela Mary T · CIK 0001410289 · Director · CEO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 742,802

F3 · shares: Represents the granting of PSUs upon achieving or exceeding $75 million of revenue over any 12 consecutive calendar month period ending on or before December 31, 2027. 150,000 PSUs vest immediately upon achieving the performance requirement and 150,000 PSUs vest on the one-year anniversary of achieving the performance requirement, subject to the continued employment through each respective vesting date.

SEC source: 0001410289-25-000006 · wk-form4_1764104104.xml · nonDerivative · entry 2

Szela Mary T · CIK 0001410289 · Director · CEO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 442,802

F2 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on November 24, 2025, subject to continued employment through the respective vesting date.

SEC source: 0001981787-25-000004 · wk-form4_1764105353.xml · derivative · entry 2

Cox Bryan F. · CIK 0001981787 · Chief of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 261,954

Underlying: Common Stock · 80,000 shares

Expires 2035-11-23

F2 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of November 24, 2025 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to continued employment through the respective vesting date.

SEC source: 0001981787-25-000004 · wk-form4_1764105353.xml · nonDerivative · entry 1

Cox Bryan F. · CIK 0001981787 · Chief of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 166,599

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on November 24, 2025, subject to continued employment through the respective vesting date.

SEC source: 0001970009-25-000004 · wk-form4_1764103242.xml · derivative · entry 2

Patience David · CIK 0001970009 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 668,899

Underlying: Common Stock · 130,000 shares

Expires 2035-11-23

F2 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of November 24, 2025 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to continued employment through the respective vesting date.

SEC source: 0001970009-25-000004 · wk-form4_1764103242.xml · nonDerivative · entry 1

Patience David · CIK 0001970009 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 265,000

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on November 24, 2025, subject to continued employment through the respective vesting date.

SEC source: 0001826667-25-000131 · wk-form4_1756498688.xml · derivative · entry 1

Patience David · CIK 0001970009 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 538,899

Underlying: Common Stock · 248,899 shares

Expires not disclosed

F1 · derivative.exercise_date: Represents the granting of stock options upon achieving or exceeding $75 million of revenue over any twelve (12) consecutive calendar month period ending on or before December 31, 2027. The options vest immediately upon achieving the performance requirement, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

F2 · derivative.expiration_date: The stock options expire on December 31, 2027 if the revenue threshold is not met.

SEC source: 0001826667-25-000121 · wk-form4_1755293353.xml · derivative · entry 2

Patience David · CIK 0001970009 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 290,000

Underlying: Common Stock · 290,000 shares

Expires 2035-08-13

F2 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option shall vest on the one-year anniversary of the vesting commencement date of July 1, 2026 (the "VCD"), and 1/36th of the remaining shares shall vest each month thereafter on the same day of the month as the VCD (or if there is no corresponding day, on the last day of the month), subject to the Reporting Person's continuous service with the Issuer on each respective vesting date.

SEC source: 0001826667-25-000121 · wk-form4_1755293353.xml · nonDerivative · entry 1

Patience David · CIK 0001970009 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200,000

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. The shares subject to the RSU Award vest in four equal annual installments commencing on July 1, 2026, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

SEC source: 0001628280-26-022792 · wk-form4_1775074153.xml · derivative · entry 2

MATLIN DAVID J · CIK 0001251956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 330,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Represents conversion price pursuant to an offer (the "Offer") the Company commenced on June 23, 2025, under which all holders of Preferred Stock could exchange their shares of Preferred Stock for Common Stock equal to the sum of the liquidation preference per share price of $10.00 and all accrued and unpaid dividends per share outstanding through August 10, 2027, divided by a $4.00 conversion price per share.

F3 · shares: On July 31, 2025, all 100,000 shares of Preferred Stock held by the Reporting Person were converted into 330,000 shares of Common Stock pursuant to the Offer.

F3 · derivative.exercise_date: On July 31, 2025, all 100,000 shares of Preferred Stock held by the Reporting Person were converted into 330,000 shares of Common Stock pursuant to the Offer.

F3 · derivative.expiration_date: On July 31, 2025, all 100,000 shares of Preferred Stock held by the Reporting Person were converted into 330,000 shares of Common Stock pursuant to the Offer.

F3 · derivative.underlying_shares: On July 31, 2025, all 100,000 shares of Preferred Stock held by the Reporting Person were converted into 330,000 shares of Common Stock pursuant to the Offer.

F3 · balance_after: On July 31, 2025, all 100,000 shares of Preferred Stock held by the Reporting Person were converted into 330,000 shares of Common Stock pursuant to the Offer.

SEC source: 0001628280-26-022792 · wk-form4_1775074153.xml · nonDerivative · entry 1

MATLIN DAVID J · CIK 0001251956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,271,944

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents shares received upon conversion of the Series A Preferred Stock (the "Preferred Stock") reported in Table II.

SEC source: 0001628280-26-026014 · wk-form4_1776717403.xml · derivative · entry 2

Frankenius Equity AB · CIK 0001988262 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 759,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Represents conversion price pursuant to an offer (the "Offer") the Company commenced on June 23, 2025, under which all holders of Preferred Stock could exchange their shares of Preferred Stock for Common Stock equal to the sum of the liquidation preference per share price of $10.00 and all accrued and unpaid dividends per share outstanding through August 10, 2027, divided by a $4.00 conversion price per share.

F3 · shares: On July 31, 2025, all 230,000 shares of Preferred Stock held by the Reporting Person were converted into 759,000 shares of Common Stock pursuant to the Offer.

F3 · derivative.exercise_date: On July 31, 2025, all 230,000 shares of Preferred Stock held by the Reporting Person were converted into 759,000 shares of Common Stock pursuant to the Offer.

F3 · derivative.expiration_date: On July 31, 2025, all 230,000 shares of Preferred Stock held by the Reporting Person were converted into 759,000 shares of Common Stock pursuant to the Offer.

SEC source: 0001628280-26-026014 · wk-form4_1776717403.xml · nonDerivative · entry 1

Frankenius Equity AB · CIK 0001988262 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,989,748

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents shares received upon conversion of the Series A Preferred Stock (the "Preferred Stock") reported in Table II.

SEC source: 0001628280-26-046501 · wk-form5_1782936102.xml · nonDerivative · entry 3

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,309

F1 · shares: Represents shares acquired by the Reporting Person through the Issuer's Employee Stock Purchase Plan in a transaction exempt under Rule 16b-3.

SEC source: 0001628280-26-046511 · wk-form5_1782936210.xml · nonDerivative · entry 2

Szela Mary T · CIK 0001410289 · Director · CEO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 596,726

F1 · shares: Represents shares acquired by the Reporting Person through the Issuer's Employee Stock Purchase Plan in a transaction exempt under Rule 16b-3.

SEC source: 0001826667-25-000087 · wk-form4_1751055766.xml · derivative · entry 1

HICKS KERRY R · CIK 0001110473 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,222

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000081 · wk-form4_1751055368.xml · derivative · entry 1

Valle William · CIK 0002018493 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,250

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000089 · wk-form4_1751056010.xml · derivative · entry 1

Gordon Gary B. · CIK 0001811354 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,250

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000083 · wk-form4_1751055493.xml · derivative · entry 1

Murphy Sean · CIK 0001685042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 554,681

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000079 · wk-form4_1751055139.xml · derivative · entry 1

Wahlstrom Mats · CIK 0001459154 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200,945

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000085 · wk-form4_1751055648.xml · derivative · entry 1

MATLIN DAVID J · CIK 0001251956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000091 · wk-form4_1751056186.xml · derivative · entry 1

Desai Arjun JJ · CIK 0001982985 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 15,000 shares

Expires 2035-06-11

F1 · derivative.exercise_date: The shares subject to the option shall fully vest on the one-year anniversary of the grant date of June 12, 2025, provided that the shares subject to the option will in any case be fully vested on the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person's continued service with the Issuer.

SEC source: 0001826667-25-000063 · wk-form4_1747863414.xml · nonDerivative · entry 1

Young James Emmett · CIK 0002050748 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,663

F1 · shares: The granted RSUs vest immediately.

SEC source: 0001826667-25-000059 · wk-form4_1747863107.xml · nonDerivative · entry 2

Devlin Jodi · CIK 0001992151 · Chief of Clinical Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,764

F2 · shares: The sale of the shares was to cover the tax liability associated with the granted RSUs.

SEC source: 0001826667-25-000059 · wk-form4_1747863107.xml · nonDerivative · entry 1

Devlin Jodi · CIK 0001992151 · Chief of Clinical Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,528

F1 · shares: The granted RSUs vest immediately.

SEC source: 0001826667-25-000053 · wk-form4_1747862841.xml · nonDerivative · entry 2

Stevens Jennifer · CIK 0001982621 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,640

F2 · shares: The sale of the shares was to cover the tax liability associated with the granted RSUs.

SEC source: 0001826667-25-000053 · wk-form4_1747862841.xml · nonDerivative · entry 1

Stevens Jennifer · CIK 0001982621 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,344

F1 · shares: The granted RSUs vest immediately.

SEC source: 0001826667-25-000057 · wk-form4_1747863026.xml · nonDerivative · entry 2

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,101

F2 · shares: The sale of the shares was to cover the tax liability associated with the granted RSUs.

SEC source: 0001826667-25-000057 · wk-form4_1747863026.xml · nonDerivative · entry 1

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,698

F1 · shares: The granted RSUs vest immediately.

SEC source: 0001826667-25-000055 · wk-form4_1747862929.xml · nonDerivative · entry 1

Murphy Sean · CIK 0001685042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 123,989

F1 · shares: The granted RSUs vest immediately.

SEC source: 0001826667-25-000061 · wk-form4_1747863185.xml · nonDerivative · entry 2

Cox Bryan F. · CIK 0001981787 · Chief of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,415

F2 · shares: The sale of the shares was to cover the tax liability associated with the granted RSUs.

SEC source: 0001826667-25-000061 · wk-form4_1747863185.xml · nonDerivative · entry 1

Cox Bryan F. · CIK 0001981787 · Chief of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 124,179

F1 · shares: The granted RSUs vest immediately.

SEC source: 0001415889-25-004688 · form4-02192025_100242.xml · nonDerivative · entry 1

Young James Emmett · CIK 0002050748 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,488

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. 12.5% of the shares subject to the RSU Award shall vest on the grant date of February 18, 2025; 25% of the shares subject to the RSU Award shall vest on each of May 15, 2025, August 15, 2025, and November 14, 2025; and the remaining shares subject to the RSU Award will vest on February 13, 2026, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

SEC source: 0001415889-25-004680 · form4-02192025_100231.xml · nonDerivative · entry 1

Devlin Jodi · CIK 0001992151 · Chief of Clinical Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,397

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. 12.5% of the shares subject to the RSU Award shall vest on the grant date of February 18, 2025; 25% of the shares subject to the RSU Award shall vest on each of May 15, 2025, August 15, 2025, and November 14, 2025; and the remaining shares subject to the RSU Award will vest on February 13, 2026, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

SEC source: 0001415889-25-004687 · form4-02192025_100258.xml · nonDerivative · entry 1

Stevens Jennifer · CIK 0001982621 · CHIEF REGULATORY OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,889

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. 12.5% of the shares subject to the RSU Award shall vest on the grant date of February 18, 2025; 25% of the shares subject to the RSU Award shall vest on each of May 15, 2025, August 15, 2025, and November 14, 2025; and the remaining shares subject to the RSU Award will vest on February 13, 2026, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

SEC source: 0001415889-25-004684 · form4-02192025_100219.xml · nonDerivative · entry 1

Marshak Richard · CIK 0001982638 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,270

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. 12.5% of the shares subject to the RSU Award shall vest on the grant date of February 18, 2025; 25% of the shares subject to the RSU Award shall vest on each of May 15, 2025, August 15, 2025, and November 14, 2025; and the remaining shares subject to the RSU Award will vest on February 13, 2026, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.

SEC source: 0001415889-25-004691 · form4-02192025_100215.xml · nonDerivative · entry 1

Murphy Sean · CIK 0001685042 · Director · Chief Manuf, Strategy&Bus Dev.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,105

F1 · shares: Represents grant of restricted stock units (the "RSU Award") payable solely in common stock of the Issuer. 12.5% of the shares subject to the RSU Award shall vest on the grant date of February 18, 2025; 25% of the shares subject to the RSU Award shall vest on each of May 15, 2025, August 15, 2025, and November 14, 2025; and the remaining shares subject to the RSU Award will vest on February 13, 2026, subject to the Reporting Person's continued service with the Issuer on each respective vesting date.