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TELA

TELA Bio, Inc.

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7381
SEC CIK
0001561921
Parsed reports
268

Last 12 months

Inside the activity.

5 purchase rows · 0 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
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MonthPurchasesSales
Nov 202510
Dec 202500
Jan 202600
Feb 202600
Mar 202600
Apr 202600
May 202600
Jun 202600
Jul 202600
Aug 202620
Sep 202620
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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 16, 2022 Filed Aug 16, 2022 20:05 UTC PurchaseCommon Stock, par value $0.001 per share 15,000 $8.00 $120,000.00
Disclosure

SEC source: 0001493152-22-023186 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 120,000

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
August 16, 2022 Filed Aug 16, 2022 20:05 UTC PurchaseCommon Stock, par value $0.001 per share 300,000 $8.00 $2,400,000.00
Disclosure

SEC source: 0001493152-22-023186 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,880,000

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
August 16, 2022 Filed Sep 15, 2022 20:05 UTC PurchaseCommon Stock, par value $0.001 per share 221 $8.10 $1,789.90
Disclosure

SEC source: 0001493152-22-025979 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 120,217

F3 · price: This transaction was executed in multiple trades at prices ranging from $8.09 to $8.10; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
August 16, 2022 Filed Sep 15, 2022 20:05 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $8.10 $40,495.50
Disclosure

SEC source: 0001493152-22-025979 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,885,000

F3 · price: This transaction was executed in multiple trades at prices ranging from $8.09 to $8.10; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
August 10, 2022 Filed Aug 12, 2022 10:41 UTC PurchaseCommon Stock, par value $0.001 per share 479 $8.52 $4,082.18
Disclosure

SEC source: 0001493152-22-022193 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 105,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.5223, and a range of $8.45 to $8.55. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
August 10, 2022 Filed Aug 12, 2022 10:41 UTC PurchaseCommon Stock, par value $0.001 per share 11,500 $8.52 $98,006.45
Disclosure

SEC source: 0001493152-22-022193 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,580,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.5223, and a range of $8.45 to $8.55. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
August 01, 2022 Filed Aug 3, 2022 01:39 UTC PurchaseCommon Stock, par value $0.001 per share 479 $7.96 $3,812.74
Disclosure

SEC source: 0001493152-22-021074 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 100,679

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $7.9598, and a range of $7.90 to $8.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
August 01, 2022 Filed Aug 3, 2022 01:39 UTC PurchaseCommon Stock, par value $0.001 per share 4,500 $7.96 $35,819.10
Disclosure

SEC source: 0001493152-22-021074 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,565,500

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $7.9598, and a range of $7.90 to $8.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
August 01, 2022 Filed Aug 12, 2022 13:27 UTC Amendment PurchaseCommon Stock, par value $0.001 per share 479 $7.96 $3,812.74
Disclosure

SEC source: 0001493152-22-022214 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 100,679

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $7.9598, and a range of $7.90 to $8.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
August 01, 2022 Filed Aug 12, 2022 13:27 UTC Amendment PurchaseCommon Stock, par value $0.001 per share 4,500 $7.96 $35,819.10
Disclosure

SEC source: 0001493152-22-022214 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,568,500

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $7.9598, and a range of $7.90 to $8.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
July 22, 2022 Filed Jul 22, 2022 21:48 UTC PurchaseCommon Stock, par value $0.001 per share 200 $8.02 $1,604.20
Disclosure

SEC source: 0001493152-22-020185 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 100,200

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.021, and a range of $8.00 to $8.03. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
July 22, 2022 Filed Jul 22, 2022 21:48 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $8.02 $40,105.00
Disclosure

SEC source: 0001493152-22-020185 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,564,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.021, and a range of $8.00 to $8.03. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
July 21, 2022 Filed Jul 21, 2022 21:50 UTC PurchaseCommon Stock, par value $0.001 per share 833 $8.08 $6,727.97
Disclosure

SEC source: 0001493152-22-020067 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 100,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.0297, and a range of $8.00 to $8.05. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
July 21, 2022 Filed Jul 21, 2022 21:50 UTC PurchaseCommon Stock, par value $0.001 per share 9,500 $8.03 $76,282.15
Disclosure

SEC source: 0001493152-22-020067 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,559,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.0297, and a range of $8.00 to $8.05. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
July 20, 2022 Filed Jul 20, 2022 22:55 UTC PurchaseCommon Stock, par value $0.001 per share 600 $8.08 $4,846.08
Disclosure

SEC source: 0001493152-22-019956 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 99,167

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.0768, and a range of $8.00 to $8.08. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
July 20, 2022 Filed Jul 20, 2022 22:55 UTC PurchaseCommon Stock, par value $0.001 per share 4,500 $8.08 $36,345.60
Disclosure

SEC source: 0001493152-22-019956 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,549,500

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $8.0768, and a range of $8.00 to $8.08. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
July 14, 2022 Filed Feb 16, 2024 16:10 UTC
EW HEALTHCARE PARTNERS FUND 2, L.P.10% owner · See Remarks
PurchaseCommon Stock, par value $0.001 per share 5,000 $8.01 $40,050.00
Disclosure

SEC source: 0000950170-24-016357 · ownership.xml · nonDerivative · entry 27

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · 10% owner · See Remarks

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · 10% owner · See Remarks

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner · See Remarks

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner · See Remarks

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Remarks

Disclosed balance after: 3,610,709

F43 · balance_after: The share total shown above is the aggregate amount of shares purchased by EW Fund 2 and EW Fund 2-A on the date set forth above. EW Fund 2 purchased 1,965 shares of the amount shown above and EW Fund 2-A purchased 3,035 shares of the amount shown above.

Read SEC document
July 13, 2022 Filed Jul 13, 2022 19:55 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $8.03 $40,150.00
Disclosure

SEC source: 0000899243-22-026036 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,605,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,434,511 shares and Fund 2-A now holds a total of 2,171,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 12, 2022 Filed Jul 13, 2022 19:55 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $8.02 $40,100.00
Disclosure

SEC source: 0000899243-22-026036 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,600,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,434,511 shares and Fund 2-A now holds a total of 2,171,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 11, 2022 Filed Jul 13, 2022 19:55 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $8.02 $40,100.00
Disclosure

SEC source: 0000899243-22-026036 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,595,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,434,511 shares and Fund 2-A now holds a total of 2,171,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 08, 2022 Filed Jul 8, 2022 17:58 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.96 $39,800.00
Disclosure

SEC source: 0000899243-22-025833 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,590,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,430,011 shares and Fund 2-A now holds a total of 2,160,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 07, 2022 Filed Jul 8, 2022 17:58 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $8.07 $40,350.00
Disclosure

SEC source: 0000899243-22-025833 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,585,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,430,011 shares and Fund 2-A now holds a total of 2,160,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 06, 2022 Filed Jul 8, 2022 17:58 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.86 $39,300.00
Disclosure

SEC source: 0000899243-22-025833 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,580,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,430,011 shares and Fund 2-A now holds a total of 2,160,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 05, 2022 Filed Jul 5, 2022 19:37 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.52 $37,600.00
Disclosure

SEC source: 0000899243-22-025125 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,575,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,425,511 shares and Fund 2-A now holds a total of 2,150,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 01, 2022 Filed Jul 5, 2022 19:37 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.27 $36,350.00
Disclosure

SEC source: 0000899243-22-025125 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,570,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,425,511 shares and Fund 2-A now holds a total of 2,150,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
July 01, 2022 Filed Jul 5, 2022 22:30 UTC PurchaseCommon Stock, par value $0.001 per share 200 $7.00 $1,400.00
Disclosure

SEC source: 0001493152-22-018583 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 98,567

F1 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
June 30, 2022 Filed Jun 30, 2022 23:20 UTC PurchaseCommon Stock, par value $0.001 per share 567 $7.00 $3,969.00
Disclosure

SEC source: 0001493152-22-018273 · ownership.xml · nonDerivative · entry 3

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 98,367

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
June 30, 2022 Filed Jun 30, 2022 23:20 UTC PurchaseCommon Stock, par value $0.001 per share 2,998 $7.00 $20,986.00
Disclosure

SEC source: 0001493152-22-018273 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,545,000

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
June 30, 2022 Filed Jul 5, 2022 19:37 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.07 $35,350.00
Disclosure

SEC source: 0000899243-22-025125 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,565,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,425,511 shares and Fund 2-A now holds a total of 2,150,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 29, 2022 Filed Jun 30, 2022 23:20 UTC PurchaseCommon Stock, par value $0.001 per share 2 $6.99 $13.98
Disclosure

SEC source: 0001493152-22-018273 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,542,002

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 18:13 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.10 $35,500.00
Disclosure

SEC source: 0000899243-22-024535 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,560,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,421,011 shares and Fund 2-A now holds a total of 2,139,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 28, 2022 Filed Jun 29, 2022 18:13 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.09 $35,450.00
Disclosure

SEC source: 0000899243-22-024535 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,555,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,421,011 shares and Fund 2-A now holds a total of 2,139,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 27, 2022 Filed Jun 29, 2022 18:13 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.22 $36,100.00
Disclosure

SEC source: 0000899243-22-024535 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,550,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,421,011 shares and Fund 2-A now holds a total of 2,139,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 24, 2022 Filed Jun 24, 2022 19:06 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $7.06 $35,300.00
Disclosure

SEC source: 0000899243-22-024087 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,545,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,416,511 shares and Fund 2-A now holds a total of 2,129,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 23, 2022 Filed Jun 24, 2022 19:06 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $6.99 $34,950.00
Disclosure

SEC source: 0000899243-22-024087 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,540,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,416,511 shares and Fund 2-A now holds a total of 2,129,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 22, 2022 Filed Jun 22, 2022 21:18 UTC PurchaseCommon Stock, par value $0.001 per share 50,000 $6.50 $324,975.00
Disclosure

SEC source: 0001493152-22-017529 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,540,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $6.4995, and a range of $5.94 to $6.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
June 22, 2022 Filed Jun 24, 2022 19:06 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $6.47 $32,350.00
Disclosure

SEC source: 0000899243-22-024087 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,535,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,416,511 shares and Fund 2-A now holds a total of 2,129,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 22, 2022 Filed Jun 24, 2022 23:45 UTC PurchaseCommon Stock, par value $0.001 per share 400 $6.99 $2,796.00
Disclosure

SEC source: 0001493152-22-017768 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 97,800

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Read SEC document
June 22, 2022 Filed Jun 24, 2022 23:45 UTC PurchaseCommon Stock, par value $0.001 per share 2,000 $6.99 $13,980.00
Disclosure

SEC source: 0001493152-22-017768 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,542,000

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Read SEC document
June 21, 2022 Filed Jun 21, 2022 18:43 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $6.25 $31,250.00
Disclosure

SEC source: 0000899243-22-023457 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,530,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,412,011 shares and Fund 2-A now holds a total of 2,118,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

Read SEC document
June 17, 2022 Filed Jun 21, 2022 18:43 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $6.17 $30,850.00
Disclosure

SEC source: 0000899243-22-023457 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,525,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,412,011 shares and Fund 2-A now holds a total of 2,118,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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June 16, 2022 Filed Jun 21, 2022 18:43 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $6.01 $30,050.00
Disclosure

SEC source: 0000899243-22-023457 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,520,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,412,011 shares and Fund 2-A now holds a total of 2,118,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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June 15, 2022 Filed Jun 15, 2022 18:11 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $5.90 $29,500.00
Disclosure

SEC source: 0000899243-22-022665 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,515,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,407,511 shares and Fund 2-A now holds a total of 2,108,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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June 14, 2022 Filed Jun 15, 2022 18:11 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $5.86 $29,300.00
Disclosure

SEC source: 0000899243-22-022665 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,510,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,407,511 shares and Fund 2-A now holds a total of 2,108,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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June 13, 2022 Filed Jun 15, 2022 18:11 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $5.81 $29,050.00
Disclosure

SEC source: 0000899243-22-022665 · doc4.xml · nonDerivative · entry 1

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,505,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,407,511 shares and Fund 2-A now holds a total of 2,108,198 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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June 10, 2022 Filed Jun 10, 2022 18:04 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $5.80 $29,000.00
Disclosure

SEC source: 0000899243-22-021988 · doc4.xml · nonDerivative · entry 3

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,500,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,403,011 shares and Fund 2-A now holds a total of 2,097,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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June 10, 2022 Filed Jun 10, 2022 22:16 UTC PurchaseCommon Stock, par value $0.001 per share 2,500 $5.60 $14,006.00
Disclosure

SEC source: 0001493152-22-016481 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 95,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $5.6024, and a range of $5.27-$5.80. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

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June 10, 2022 Filed Jun 10, 2022 22:16 UTC PurchaseCommon Stock, par value $0.001 per share 25,000 $5.60 $140,060.00
Disclosure

SEC source: 0001493152-22-016481 · ownership.xml · nonDerivative · entry 1

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Opaleye, L.P.

Disclosed balance after: 1,490,000

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $5.6024, and a range of $5.27-$5.80. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

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June 10, 2022 Filed Jun 22, 2022 21:18 UTC PurchaseCommon Stock, par value $0.001 per share 2,400 $6.50 $15,598.80
Disclosure

SEC source: 0001493152-22-017529 · ownership.xml · nonDerivative · entry 2

Opaleye Management Inc. · CIK 0001595855 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 97,400

F3 · price: The common stock was purchased by the reporting person in open market transactions on the transaction date, with an average purchase price of $6.4995, and a range of $5.94 to $6.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.

F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

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June 09, 2022 Filed Jun 10, 2022 18:04 UTC PurchaseCommon Stock, par value $0.001 per share 5,000 $6.17 $30,850.00
Disclosure

SEC source: 0000899243-22-021988 · doc4.xml · nonDerivative · entry 2

EW HEALTHCARE PARTNERS FUND 2, L.P. · CIK 0001746777 · See footnote 2

EW HEALTHCARE PARTNERS FUND 2-A, L.P. · CIK 0001746779 · See footnote 2

EW Healthcare Partners Fund 2 GP, L.P. · CIK 0001793943 · 10% owner

EW Healthcare Partners Fund 2-UGP, LLC · CIK 0001793948 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,495,709

F1 · ownership.nature: The Share totals shown above are the aggregate amounts of shares purchased by EW Healthcare Partners Fund 2, L.P. ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. ("Fund 2-A") on the dates set forth above. Fund 2 purchased 1,500 shares of the amount shown for each date above, and Fund 2-A purchased 3,500 shares of the amount shown above on each such date. Fund 2 now holds a total of 1,403,011 shares and Fund 2-A now holds a total of 2,097,698 shares of the Issuer.

F2 · ownership.nature: EW Healthcare Partners Fund 2 GP, L.P. (the "EW Funds GP"), is the general partner of each of EW Healthcare Partners Fund 2, L.P . ("Fund 2") and EW Healthcare Partners Fund 2-A, L.P. (''EW Fund 2-A" and together with EW Fund 2, the ''EW Funds"). EW Healthcare Partners Fund 2- UGP, LLC (the "General Partner") is the general partner of EW Funds GP. The General Partner holds sole voting and dispositive power over the shares held by each of the EW Funds (the "Shares''). The managers of the General Partner are Martin P. Sutter, Ron Eastman, Scott Barry and Petri Vainio (collectively, the ''Managers'') and may exercise voting and investment control over the Shares only by majority action of the Managers. Each individual Manager, the EW Funds GP and the General Partner disclaims ownership over the Shares except to the extent of his or its respective pecuniary interest therein.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.