STOK

SEC source: 0001415889-24-015976 · form4-06072024_080616.xml · derivative · entry 1

Burstein Jennifer · CIK 0001640069 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,639

Underlying: Common Stock · 7,639 shares

Expires 2034-06-04

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 5, 2025 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-24-015974 · form4-06072024_080629.xml · derivative · entry 1

Smith Julie · CIK 0001557928 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,639

Underlying: Common Stock · 7,639 shares

Expires 2034-06-04

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 5, 2025 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-24-015970 · form4-06072024_080629.xml · derivative · entry 1

SMITH IAN F · CIK 0001197032 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,639

Underlying: Common Stock · 7,639 shares

Expires 2034-06-04

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 5, 2025 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-24-015965 · form4-06072024_080651.xml · derivative · entry 1

TZIANABOS ARTHUR · CIK 0001586226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,639

Underlying: Common Stock · 7,639 shares

Expires 2034-06-04

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 5, 2025 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-24-015968 · form4-06072024_080627.xml · derivative · entry 1

Menzel Garry E · CIK 0001556064 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,639

Underlying: Common Stock · 7,639 shares

Expires 2034-06-04

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 5, 2025 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-24-015559 · form4-06052024_080649.xml · derivative · entry 4

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 10,000 shares

Expires 2028-04-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This fully-vested option vested as to 1/4th of the total award on October 2, 2018, with 1/48th of the total award vesting monthly thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-015559 · form4-06052024_080649.xml · nonDerivative · entry 3

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,485

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 14, 2023.

SEC source: 0001415889-24-015559 · form4-06052024_080649.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,588

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 14, 2023.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.75 to $15.73 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-015559 · form4-06052024_080649.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,485

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-014093 · form4-05222024_080503.xml · derivative · entry 3

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 46,000

Underlying: Common Stock · 50,000 shares

Expires 2026-02-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option is fully vested.

SEC source: 0001415889-24-014093 · form4-05222024_080503.xml · nonDerivative · entry 2

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 29, 2023.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.91 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-014093 · form4-05222024_080503.xml · nonDerivative · entry 1

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 50,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-014082 · form4-05222024_080500.xml · derivative · entry 3

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,801

Underlying: Common Stock · 8,599 shares

Expires 2032-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vested or vests as to 1/48th of the total award on January 7, 2023, with 1/48th of the total award vesting monthly thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-014082 · form4-05222024_080500.xml · nonDerivative · entry 2

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,598

F1 · kind: The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted on December 15, 2023 by the reporting person.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.16 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote

SEC source: 0001415889-24-014082 · form4-05222024_080500.xml · nonDerivative · entry 1

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,197

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-014087 · form4-05222024_080510.xml · nonDerivative · entry 2

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 27,000

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 26, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00 to $16.08, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-014087 · form4-05222024_080510.xml · nonDerivative · entry 1

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 29,664

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 26, 2023.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.99, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-013477 · form4-05172024_080515.xml · derivative · entry 1

Leggett Thomas · CIK 0001774690 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 396,200

Underlying: Common Stock · 396,200 shares

Expires 2034-05-14

F1 · derivative.exercise_date: The stock option vests as to 1/4 of the total award on May 7, 2025, and as to 1/48 of the total award monthly thereafter, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-24-012173 · form4-05032024_080531.xml · derivative · entry 3

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 10,000 shares

Expires 2028-04-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This fully-vested option vested as to 1/4th of the total award on October 2, 2018, with 1/48th of the total award vesting monthly thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-012173 · form4-05032024_080531.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,485

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 14, 2023.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $11.00 to $11.80 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-012173 · form4-05032024_080531.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,485

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001062993-24-008547 · form4.xml · nonDerivative · entry 1

Skorpios Trust · CIK 0001869333 · 10% owner

Blue Horizon Enterprise Ltd · CIK 0001869057 · 10% owner

Ezbon International Ltd · CIK 0001869027 · 10% owner

Montrago Trustees Ltd · CIK 0001869331 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 10,843,681

F1 · ownership.nature: Blue Horizon Enterprise Ltd. ("Blue Horizon") is the direct owner of 6,905,121 shares of the issuer's common stock and Ezbon International Limited ("Ezbon") is the direct owner of 3,938,560 shares of the issuer's common stock. Skorpios Trust ("Skorpios") is the sole owner of each of Blue Horizon and Ezbon. Montrago Trustees Limited ("Montrago Trustees") is the corporate trustee of Skorpios Trust. Each of Blue Horizon and Ezbon disclaim beneficial ownership of the shares of the issuer's common stock held by the other, and each of Skorpios Trust and Montrago Trustees disclaim beneficial ownership of the issuer's securities except to the extent of their pecuniary interest therein.

SEC source: 0001415889-24-009999 · form4-04032024_080444.xml · derivative · entry 3

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Stock · 442 shares

Expires 2028-04-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This fully-vested option vested as to 1/4th of the total award on October 2, 2018, with 1/48th of the total award vesting monthly thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-009999 · form4-04032024_080444.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,485

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 14, 2023.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.62 to $13.55 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-009999 · form4-04032024_080444.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,911

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-009993 · form4-04032024_080414.xml · derivative · entry 4

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 50,000 shares

Expires 2026-02-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option is fully vested.

SEC source: 0001415889-24-009993 · form4-04032024_080414.xml · nonDerivative · entry 3

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 29, 2023.

SEC source: 0001415889-24-009993 · form4-04032024_080414.xml · nonDerivative · entry 2

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 400

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 29, 2023.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.60 to $13.59 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-009993 · form4-04032024_080414.xml · nonDerivative · entry 1

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,329

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-009532 · form4-04012024_080416.xml · nonDerivative · entry 2

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,598

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted on December 15, 2023 by the reporting person.

SEC source: 0001415889-24-009532 · form4-04012024_080416.xml · nonDerivative · entry 1

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,698

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted on December 15, 2023 by the reporting person.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.80 to $13.62 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote

SEC source: 0001415889-24-016005 · form4-06072024_080653.xml · derivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2028-03-15

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-016005 · form4-06072024_080653.xml · derivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-03-26

F1 · derivative.exercise_date: The option vested or vests as to 1/48 of the total award on April 15, 2024, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-016010 · form4-06072024_080631.xml · derivative · entry 2

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common Stock · 105,000 shares

Expires 2028-03-15

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-016010 · form4-06072024_080631.xml · derivative · entry 1

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 159,000

Underlying: Common Stock · 159,000 shares

Expires 2034-03-26

F1 · derivative.exercise_date: The option vested or vests as to 1/48 of the total award on April 15, 2024, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-016008 · form4-06072024_080616.xml · derivative · entry 2

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2028-03-15

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-016008 · form4-06072024_080616.xml · derivative · entry 1

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-03-26

F1 · derivative.exercise_date: The option vested or vests as to 1/48 of the total award on April 15, 2024, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-015998 · form4-06072024_080658.xml · derivative · entry 2

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,000

Underlying: Common Stock · 24,000 shares

Expires 2028-03-15

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-015998 · form4-06072024_080658.xml · derivative · entry 1

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2034-03-26

F1 · derivative.exercise_date: The option vested or vests as to 1/48 of the total award on April 15, 2024, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-015995 · form4-06072024_080605.xml · derivative · entry 2

Tulipano Stephen J · CIK 0001360548 · Former CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2028-03-15

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-015995 · form4-06072024_080605.xml · derivative · entry 1

Tulipano Stephen J · CIK 0001360548 · Former CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-03-26

F1 · derivative.exercise_date: The option vested or vests as to 1/48 of the total award on April 15, 2024, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-24-008689 · form4-03202024_120307.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,469

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.94 to $6.40, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-008690 · form4-03202024_120350.xml · nonDerivative · entry 2

Tulipano Stephen J · CIK 0001360548 · CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,746

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.94 to $6.40, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-008683 · form4-03202024_120318.xml · nonDerivative · entry 2

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,350

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.94 to $6.40, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-008686 · form4-03202024_120349.xml · nonDerivative · entry 2

Nash Huw M. · CIK 0001780085 · COO & CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,329

F2 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.94 to $6.40, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-008681 · form4-03202024_120354.xml · nonDerivative · entry 2

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,724

F2 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.94 to $6.40, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-24-008689 · form4-03202024_120307.xml · derivative · entry 3

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,300

Underlying: Common Stock · 13,100 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F4 · derivative.exercise_date: The award vested or vests as to 1/4th of the total shares annually beginning March 15, 2024, subject to the reporting person's continued service to the Issuer through each vesting date.

SEC source: 0001415889-24-008689 · form4-03202024_120307.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,585

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-008690 · form4-03202024_120350.xml · derivative · entry 3

Tulipano Stephen J · CIK 0001360548 · CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,300

Underlying: Common Stock · 13,100 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F4 · derivative.exercise_date: The award vested or vests as to 1/4th of the total shares annually beginning March 15, 2024, subject to the reporting person's continued service to the Issuer through each vesting date.

SEC source: 0001415889-24-008690 · form4-03202024_120350.xml · nonDerivative · entry 1

Tulipano Stephen J · CIK 0001360548 · CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,862

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.