STOK

SEC source: 0001415889-25-021024 · form4-08052025_080805.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,775

F1 · kind: The transaction reported on this Form 4 was executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 11, 2024.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.44 to $13.00 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-25-019004 · form4-07022025_080730.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,279

F1 · kind: The transaction reported on this Form 4 was executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 11, 2024.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $11.31 to $11.99 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-25-019002 · form4-07022025_080722.xml · derivative · entry 3

LEVIN ARTHUR A · CIK 0001181556 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,422

Underlying: Common Stock · 1,210 shares

Expires 2025-12-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award vested or vests as to 1/4 of the total award quarterly on the last day of March, June, September, and December, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-019002 · form4-07022025_080722.xml · nonDerivative · entry 1

LEVIN ARTHUR A · CIK 0001181556 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,420

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001062993-25-011153 · form4.xml · nonDerivative · entry 1

Skorpios Trust · CIK 0001869333 · 10% owner

Blue Horizon Enterprise Ltd · CIK 0001869057 · 10% owner

Ezbon International Ltd · CIK 0001869027 · 10% owner

Montrago Trustees Ltd · CIK 0001869331 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 3,906,181

F1 · ownership.nature: Blue Horizon Enterprise Ltd. ("Blue Horizon") is the direct owner of 2,967,621 shares of the issuer's common stock and Ezbon International Limited ("Ezbon") is the direct owner of 938,560 shares of the issuer's common stock. Skorpios Trust ("Skorpios") is the sole owner of each of Blue Horizon and Ezbon. Montrago Trustees Limited ("Montrago Trustees") is the corporate trustee of Skorpios Trust. Each of Blue Horizon and Ezbon disclaim beneficial ownership of the shares of the issuer's common stock held by the other, and each of Skorpios Trust and Montrago Trustees disclaim beneficial ownership of the issuer's securities except to the extent of their pecuniary interest therein.

SEC source: 0001415889-25-015699 · form4-06052025_120617.xml · derivative · entry 1

Krainer Adrian R. · CIK 0001780081 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,747

Underlying: Common Stock · 29,747 shares

Expires 2035-06-02

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 3, 2026 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-25-015693 · form4-06052025_120640.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,782

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 11, 2024.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.07 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-25-015701 · form4-06052025_120645.xml · derivative · entry 1

LEVIN ARTHUR A · CIK 0001181556 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,747

Underlying: Common Stock · 29,747 shares

Expires 2035-06-02

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 3, 2026 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-25-015702 · form4-06052025_120602.xml · derivative · entry 1

Smith Julie · CIK 0001557928 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,747

Underlying: Common Stock · 29,747 shares

Expires 2035-06-02

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 3, 2026 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-25-015700 · form4-06052025_120640.xml · derivative · entry 1

Menzel Garry E · CIK 0001556064 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,747

Underlying: Common Stock · 29,747 shares

Expires 2035-06-02

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 3, 2026 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-25-015698 · form4-06052025_120602.xml · derivative · entry 1

Harrison Seth Loring · CIK 0001404955 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,747

Underlying: Common Stock · 29,747 shares

Expires 2035-06-02

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 3, 2026 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-25-015695 · form4-06052025_120657.xml · derivative · entry 1

Burstein Jennifer · CIK 0001640069 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,747

Underlying: Common Stock · 29,747 shares

Expires 2035-06-02

F1 · derivative.exercise_date: The option shall vest in full on the earlier of: (i) June 3, 2026 or (ii) the date of the issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the issuer on the vesting date.

SEC source: 0001415889-25-015693 · form4-06052025_120640.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,253

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 11, 2024.

SEC source: 0001415889-25-011940 · form4-05052025_080547.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,998

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 11, 2024.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.10 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-25-011940 · form4-05052025_080547.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,788

F1 · kind: The transactions reported on this Form 4 were executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 11, 2024.

SEC source: 0001415889-25-009616 · form4-04022025_080412.xml · derivative · entry 3

LEVIN ARTHUR A · CIK 0001181556 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,632

Underlying: Common Stock · 1,210 shares

Expires 2025-12-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award vested or vests as to 1/4 of the total award quarterly on the last day of March, June, September, and December, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-009616 · form4-04022025_080412.xml · nonDerivative · entry 1

LEVIN ARTHUR A · CIK 0001181556 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,210

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-25-008710 · form4-03202025_100314.xml · derivative · entry 4

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,000

Underlying: Common Stock · 43,000 shares

Expires 2029-03-20

F5 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F6 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2026, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008710 · form4-03202025_100314.xml · derivative · entry 3

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,000

Underlying: Common Stock · 64,000 shares

Expires 2035-03-19

F4 · derivative.exercise_date: The option shall vest as to 1/48 of the total award on April 15, 2025, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008715 · form4-03202025_100340.xml · derivative · entry 1

SMITH IAN F · CIK 0001197032 · Director · Interim CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 238,420

Underlying: Common Stock · 238,420 shares

Expires 2035-03-19

F1 · derivative.exercise_date: The option vests ratably as to 1/12 of the total award on the monthly anniversary of the grant date, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-25-008714 · form4-03202025_100333.xml · derivative · entry 1

TZIANABOS ARTHUR · CIK 0001586226 · Director · Interim Executive Chair

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 122,651

Underlying: Common Stock · 122,651 shares

Expires 2035-03-19

F1 · derivative.exercise_date: The option vests ratably as to 1/12 of the total award on the monthly anniversary of the grant date, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-25-008713 · form4-03202025_100358.xml · derivative · entry 2

Leggett Thomas · CIK 0001774690 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,000

Underlying: Common Stock · 59,000 shares

Expires 2029-03-20

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2026, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008713 · form4-03202025_100358.xml · derivative · entry 1

Leggett Thomas · CIK 0001774690 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,000

Underlying: Common Stock · 89,000 shares

Expires 2035-03-19

F1 · derivative.exercise_date: The option shall vest as to 1/48 of the total award on April 15, 2025, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008711 · form4-03202025_100313.xml · derivative · entry 4

Kaye Edward M. MD · CIK 0001522780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 144,000

Underlying: Common Stock · 144,000 shares

Expires 2029-03-20

F5 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F6 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2026, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008711 · form4-03202025_100313.xml · derivative · entry 3

Kaye Edward M. MD · CIK 0001522780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 216,000

Underlying: Common Stock · 216,000 shares

Expires 2035-03-19

F4 · derivative.exercise_date: The option shall vest as to 1/48 of the total award on April 15, 2025, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008709 · form4-03202025_100334.xml · derivative · entry 4

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,000

Underlying: Common Stock · 48,000 shares

Expires 2029-03-20

F5 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F6 · derivative.exercise_date: The award vests as to 1/4 of the total award annually beginning on March 15, 2026, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008709 · form4-03202025_100334.xml · derivative · entry 3

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,000

Underlying: Common Stock · 72,000 shares

Expires 2035-03-19

F4 · derivative.exercise_date: The option shall vest as to 1/48 of the total award on April 15, 2025, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008710 · form4-03202025_100314.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,629

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.06 to $8.95 per share, inclusive.

SEC source: 0001415889-25-008712 · form4-03202025_100309.xml · derivative · entry 1

LEVIN ARTHUR A · CIK 0001181556 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,842

Underlying: Common Stock · 4,842 shares

Expires 2025-12-31

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one (1) share of the issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award vests as to 1/4 of the total award quarterly on the last day of March, June, September, and December, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008711 · form4-03202025_100313.xml · nonDerivative · entry 2

Kaye Edward M. MD · CIK 0001522780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 139,346

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.06 to $8.95 per share, inclusive.

SEC source: 0001415889-25-008709 · form4-03202025_100334.xml · nonDerivative · entry 2

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,565

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.06 to $8.95 per share, inclusive.

SEC source: 0001415889-25-008710 · form4-03202025_100314.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,962

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.11 to $8.925 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote and in footnote 3.

SEC source: 0001415889-25-008711 · form4-03202025_100313.xml · nonDerivative · entry 1

Kaye Edward M. MD · CIK 0001522780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 148,253

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.11 to $8.925 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote and in footnote 3.

SEC source: 0001415889-25-008709 · form4-03202025_100334.xml · nonDerivative · entry 1

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,510

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.11 to $8.925 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote and in footnote 3.

SEC source: 0001415889-25-008359 · form4-03182025_080350.xml · derivative · entry 4

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 10,000 shares

Expires 2028-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vested or vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008359 · form4-03182025_080350.xml · derivative · entry 3

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,200

Underlying: Common Stock · 13,100 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award vested or vests as to 1/4 of the total shares annually beginning March 15, 2024, subject to the reporting person's continued service to the Issuer through each vesting date.

SEC source: 0001415889-25-008359 · form4-03182025_080350.xml · nonDerivative · entry 2

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,846

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-25-008359 · form4-03182025_080350.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,846

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-25-008367 · form4-03182025_080351.xml · derivative · entry 4

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 6,000 shares

Expires 2028-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F4 · derivative.exercise_date: The award vested or vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008367 · form4-03182025_080351.xml · derivative · entry 3

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common Stock · 7,475 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vested or vests as to 1/4 of the total shares annually beginning March 15, 2024, subject to the reporting person's continued service to the Issuer through each vesting date.

SEC source: 0001415889-25-008367 · form4-03182025_080351.xml · nonDerivative · entry 2

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,776

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-25-008367 · form4-03182025_080351.xml · nonDerivative · entry 1

Allan Jonathan · CIK 0001966716 · GENERAL COUNSEL & CORP SEC

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,776

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: The reported total includes an aggregate 825 shares acquired pursuant to the Issuer's Employee Stock Purchase Plan in one or more transactions exempt pursuant to Rules 16b-3(c) and 16b-3(d).

SEC source: 0001415889-25-008355 · form4-03182025_080305.xml · derivative · entry 4

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,750

Underlying: Common Stock · 26,250 shares

Expires 2028-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F3 · derivative.exercise_date: The award vested or vests as to 1/4 of the total award annually beginning on March 15, 2025, subject to the reporting person's continued service to the issuer through each vesting date.

SEC source: 0001415889-25-008355 · form4-03182025_080305.xml · derivative · entry 3

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,000

Underlying: Common Stock · 35,500 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one (1) share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award vested or vests as to 1/4 of the total shares annually beginning March 15, 2024, subject to the reporting person's continued service to the Issuer through each vesting date.

SEC source: 0001415889-25-008355 · form4-03182025_080305.xml · nonDerivative · entry 2

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 158,635

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-25-008355 · form4-03182025_080305.xml · nonDerivative · entry 1

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 132,385

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-25-000084 · form4-01022025_090156.xml · derivative · entry 2

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 567,801

Underlying: Common Stock · 35,000 shares

Expires 2028-04-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option became fully vested as of October 17, 2022.

SEC source: 0001415889-25-000084 · form4-01022025_090156.xml · nonDerivative · entry 1

Kaye Edward M. MD · CIK 0001522780 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,885

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001062993-24-021228 · form4.xml · nonDerivative · entry 1

Skorpios Trust · CIK 0001869333 · 10% owner

Blue Horizon Enterprise Ltd · CIK 0001869057 · 10% owner

Ezbon International Ltd · CIK 0001869027 · 10% owner

Montrago Trustees Ltd · CIK 0001869331 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 6,906,181

F1 · ownership.nature: Blue Horizon Enterprise Ltd. ("Blue Horizon") is the direct owner of 2,967,621 shares of the issuer's common stock and Ezbon International Limited ("Ezbon") is the direct owner of 3,938,560 shares of the issuer's common stock. Skorpios Trust ("Skorpios") is the sole owner of each of Blue Horizon and Ezbon. Montrago Trustees Limited ("Montrago Trustees") is the corporate trustee of Skorpios Trust. Each of Blue Horizon and Ezbon disclaim beneficial ownership of the shares of the issuer's common stock held by the other, and each of Skorpios Trust and Montrago Trustees disclaim beneficial ownership of the issuer's securities except to the extent of their pecuniary interest therein.

SEC source: 0001415889-24-028930 · form4-12112024_091233.xml · nonDerivative · entry 1

Ticho Barry · CIK 0001780088 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,746

F1 · kind: The reported transaction represents an Issuer mandated sale to satisfy tax withholding liabilities in connection with the vesting and settlement of restricted stock units.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.99 to $13.13 per share, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.