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SPRO

Spero Therapeutics, Inc.

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7014
SEC CIK
0001701108
Parsed reports
228

Last 12 months

Inside the activity.

0 purchase rows · 9 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
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MonthPurchasesSales
Nov 202501
Dec 202500
Jan 202600
Feb 202607
Mar 202600
Apr 202600
May 202601
Jun 202600
Jul 202600
Aug 202600
Sep 202600
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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 02, 2020 Filed Jan 7, 2020 00:06 UTC GrantStock Option (right to buy) · Derivative 5,408 $6.47 Strike: $9.87 $34,989.76
Disclosure

SEC source: 0000899243-20-000629 · doc4.xml · derivative · entry 1

FORMELA JEAN FRANCOIS · CIK 0001030575 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,408

Underlying: Common Stock · 5,408 shares

Expires 2030-01-02

F2 · price: This stock option was issued to the Reporting Person, who elected to take stock options in lieu of $35,000 in cash compensation for services as a director, pursuant to the Issuer's non-employee director compensation policy. The proceeds of any sales of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Advisors, LLC and as such, the Reporting Person disclaims his beneficial ownership of the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

F1 · derivative.exercise_date: This stock option shall vest in four quarterly installments on the last day of each calendar quarter during the calendar year subject to the Reporting Person's continued service as a non-employee director.

Read SEC document
January 02, 2020 Filed Jan 7, 2020 00:09 UTC GrantStock Option (right to buy) · Derivative 2,704 $6.47 Strike: $9.87 $17,494.88
Disclosure

SEC source: 0000899243-20-000631 · doc4.xml · derivative · entry 1

THOMAS FRANK E · CIK 0001242616 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,704

Underlying: Common Stock · 2,704 shares

Expires 2030-01-02

F2 · price: This stock option was issued to the Reporting Person, who elected to take stock options in lieu of $17,500 in cash compensation for services as a director, pursuant to the Issuer's non-employee director compensation policy.

F1 · derivative.exercise_date: This stock option shall vest in four quarterly installments on the last day of each calendar quarter during the calendar year subject to the Reporting Person's continued service as a non-employee director.

Read SEC document
January 02, 2020 Filed Jan 7, 2020 00:05 UTC GrantStock Option (right to buy) · Derivative 5,408 $6.47 Strike: $9.87 $34,989.76
Disclosure

SEC source: 0000899243-20-000628 · doc4.xml · derivative · entry 1

VINK PATRICK V.J.J. · CIK 0001557501 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,408

Underlying: Common Stock · 5,408 shares

Expires 2030-01-02

F2 · price: This stock option was issued to the Reporting Person, who elected to take stock options in lieu of $35,000 in cash compensation for services as a director, pursuant to the Issuer's non-employee director compensation policy.

F1 · derivative.exercise_date: This stock option shall vest in four quarterly installments on the last day of each calendar quarter during the calendar year subject to the Reporting Person's continued service as a non-employee director.

Read SEC document
January 02, 2020 Filed Jan 7, 2020 00:03 UTC GrantStock Option (right to buy) · Derivative 5,408 $6.47 Strike: $9.87 $34,989.76
Disclosure

SEC source: 0000899243-20-000625 · doc4.xml · derivative · entry 1

Deshpande Milind · CIK 0001378588 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,408

Underlying: Common Stock · 5,408 shares

Expires 2030-01-02

F2 · price: This stock option was issued to the Reporting Person, who elected to take stock options in lieu of $35,000 in cash compensation for services as a director, pursuant to the Issuer's non-employee director compensation policy.

F1 · derivative.exercise_date: This stock option shall vest in four quarterly installments on the last day of each calendar quarter during the calendar year subject to the Reporting Person's continued service as a non-employee director.

Read SEC document
June 05, 2019 Filed Jun 5, 2019 22:48 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $10.67 $0.00
Disclosure

SEC source: 0000899243-19-015667 · doc4.xml · derivative · entry 1

FORMELA JEAN FRANCOIS · CIK 0001030575 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2029-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2020 subject to the Reporting Person's continued service as a director through the vesting date.

F2 · ownership.direct: The reporting person is a member of Atlas Venture Associates IX, LLC ("AVA IX LLC") and is obligated to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the equity grants to Atlas Venture Advisors, L.P. As such, the Reporting Person disclaims beneficial ownership to the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

Read SEC document
June 05, 2019 Filed Jun 5, 2019 22:54 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $10.67 $0.00
Disclosure

SEC source: 0000899243-19-015673 · doc4.xml · derivative · entry 1

Smith Cynthia · CIK 0001609480 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2029-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2020 subject to the Reporting Person's continued service as a director through the vesting date.

Read SEC document
June 05, 2019 Filed Jun 5, 2019 22:53 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $10.67 $0.00
Disclosure

SEC source: 0000899243-19-015672 · doc4.xml · derivative · entry 1

Pottage John C Jr · CIK 0001378587 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2029-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2020 subject to the Reporting Person's continued service as a director through the vesting date.

Read SEC document
June 05, 2019 Filed Jun 5, 2019 22:50 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $10.67 $0.00
Disclosure

SEC source: 0000899243-19-015668 · doc4.xml · derivative · entry 1

THOMAS FRANK E · CIK 0001242616 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2029-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2020 subject to the Reporting Person's continued service as a director through the vesting date.

Read SEC document
June 05, 2019 Filed Jun 5, 2019 22:47 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $10.67 $0.00
Disclosure

SEC source: 0000899243-19-015665 · doc4.xml · derivative · entry 1

Deshpande Milind · CIK 0001378588 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2029-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2020 subject to the Reporting Person's continued service as a director through the vesting date.

Read SEC document
June 05, 2019 Filed Jun 5, 2019 22:45 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $10.67 $0.00
Disclosure

SEC source: 0000899243-19-015663 · doc4.xml · derivative · entry 1

VINK PATRICK V.J.J. · CIK 0001557501 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2029-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2020 subject to the Reporting Person's continued service as a director through the vesting date.

Read SEC document
March 29, 2019 Filed Mar 29, 2019 23:29 UTC GrantStock Option (right to buy) · Derivative 12,146 $0.00 Strike: $12.81 $0.00
Disclosure

SEC source: 0000899243-19-009318 · doc4.xml · derivative · entry 1

Smith Cynthia · CIK 0001609480 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,146

Underlying: Common Stock · 12,146 shares

Expires 2029-03-29

F1 · derivative.exercise_date: The shares underlying this option will vest in thirty-six equal monthly installments at the end of each successive month following March 29, 2019, subject to the Reporting Person's continued service as a director through the applicable vesting dates.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 00:23 UTC
Parr Thomas R JRChief Scientific Officer
GrantStock Option (Right to Buy) · Derivative 35,000 $0.00 Strike: $6.26 $0.00
Disclosure

SEC source: 0000899243-19-000183 · doc4.xml · derivative · entry 1

Parr Thomas R JR · CIK 0001413008 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2029-01-02

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on January 2, 2020, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 00:20 UTC
Melnick David A.Chief Medical Officer
GrantStock Option (Right to Buy) · Derivative 65,000 $0.00 Strike: $6.26 $0.00
Disclosure

SEC source: 0000899243-19-000181 · doc4.xml · derivative · entry 1

Melnick David A. · CIK 0001726485 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 65,000 shares

Expires 2029-01-02

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on January 2, 2020, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 00:18 UTC
Larkin CristinaChief Operating Officer
GrantStock Option (Right to Buy) · Derivative 65,000 $0.00 Strike: $6.26 $0.00
Disclosure

SEC source: 0000899243-19-000179 · doc4.xml · derivative · entry 1

Larkin Cristina · CIK 0001721173 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 65,000 shares

Expires 2029-01-02

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on January 2, 2020, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 00:16 UTC
Sendek JoelChief Financial Officer
GrantStock Option (Right to Buy · Derivative 65,000 $0.00 Strike: $6.26 $0.00
Disclosure

SEC source: 0000899243-19-000178 · doc4.xml · derivative · entry 1

Sendek Joel · CIK 0001720875 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 65,000 shares

Expires 2029-01-02

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on January 2, 2020, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 00:12 UTC
Mahadevia AnkitDirector · CEO and President
GrantStock Option (Right to Buy) · Derivative 180,000 $0.00 Strike: $6.26 $0.00
Disclosure

SEC source: 0000899243-19-000175 · doc4.xml · derivative · entry 1

Mahadevia Ankit · CIK 0001720974 · Director · CEO and President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,000

Underlying: Common Stock · 180,000 shares

Expires 2029-01-02

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on January 2, 2020, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
September 21, 2018 Filed Sep 21, 2018 21:38 UTC GrantStock Option (right to buy) · Derivative 12,146 $0.00 Strike: $10.25 $0.00
Disclosure

SEC source: 0000899243-18-025024 · doc4.xml · derivative · entry 1

Pottage John C Jr · CIK 0001378587 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,146

Underlying: Common Stock · 12,146 shares

Expires 2028-09-21

F1 · derivative.exercise_date: The shares underlying this option will vest in thirty-six equal monthly installments at the end of each successive month following September 21, 2018, subject to the Reporting Person's continued service as a director through the applicable vesting dates.

Read SEC document
July 17, 2018 Filed Jul 17, 2018 21:01 UTC
GSK plc10% owner
PurchaseCommon Stock 80,000 $12.50 $1,000,000.00
Disclosure

SEC source: 0000903423-18-000400 · glaxo-spero.xml · nonDerivative · entry 1

GLAXOSMITHKLINE PLC · CIK 0001131399 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By S.R. One, Limited

Disclosed balance after: 1,934,006

F1 · ownership.nature: S.R. One, Limited acquired 80,000 common shares of the Issuer in connection with the Issuer's offering. Shares are held of record by S.R. One, Limited, an indirect, wholly-owned subsidiary of GlaxoSmithKline plc (Reporting Person).

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 1,600 $0.00 Strike: $5.90 $0.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · derivative · entry 12

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,888

Underlying: Common Stock · 1,600 shares

Expires 2027-07-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: All shares underlying this option were fully vested as of July 6, 2017.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 200 $17.92 $3,584.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 10

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,817

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 200 $17.90 $3,580.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 9

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,017

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 100 $17.71 $1,770.50
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 8

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,217

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 100 $17.62 $1,762.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 7

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,317

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 400 $17.58 $7,032.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 6

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,417

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 100 $17.55 $1,754.50
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 5

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,817

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 500 $17.50 $8,750.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 4

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,917

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 06, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
Exercise / conversionCommon Stock 1,600 $5.90 $9,440.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 3

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,417

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:45 UTC
Larkin CristinaChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 4,000 $0.00 Strike: $5.90 $0.00
Disclosure

SEC source: 0000899243-18-019568 · doc4.xml · derivative · entry 3

Larkin Cristina · CIK 0001721173 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,434

Underlying: Common Stock · 4,000 shares

Expires 2027-07-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The shares underlying this option vested as to 25% on March 7, 2017, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:45 UTC
Larkin CristinaChief Operating Officer
SaleCommon Stock 4,000 $17.50 $70,000.00
Disclosure

SEC source: 0000899243-18-019568 · doc4.xml · nonDerivative · entry 2

Larkin Cristina · CIK 0001721173 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,500

F1 · kind: The option exercises and related sales reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:45 UTC
Larkin CristinaChief Operating Officer
Exercise / conversionCommon Stock 4,000 $5.90 $23,600.00
Disclosure

SEC source: 0000899243-18-019568 · doc4.xml · nonDerivative · entry 1

Larkin Cristina · CIK 0001721173 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and related sales reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:44 UTC
Sendek JoelChief Financial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,000 $0.00 Strike: $5.90 $0.00
Disclosure

SEC source: 0000899243-18-019567 · doc4.xml · derivative · entry 3

Sendek Joel · CIK 0001720875 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,833

Underlying: Common Stock · 2,000 shares

Expires 2027-07-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The shares underlying this option vested as to 25% on May 1, 2018, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:44 UTC
Sendek JoelChief Financial Officer
SaleCommon Stock 2,000 $17.50 $35,000.00
Disclosure

SEC source: 0000899243-18-019567 · doc4.xml · nonDerivative · entry 2

Sendek Joel · CIK 0001720875 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,181

F1 · kind: The option exercises and related sales reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 10,181 shares of common stock held by the Joel D. Sendek Retained Annuity Trust No. 1, of which the Reporting Person is a trustee.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:44 UTC
Sendek JoelChief Financial Officer
Exercise / conversionCommon Stock 2,000 $5.90 $11,800.00
Disclosure

SEC source: 0000899243-18-019567 · doc4.xml · nonDerivative · entry 1

Sendek Joel · CIK 0001720875 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,181

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and related sales reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 10,181 shares of common stock held by the Joel D. Sendek Retained Annuity Trust No. 1, of which the Reporting Person is a trustee.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 3,076 $0.00 Strike: $5.90 $0.00
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · derivative · entry 11

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,488

Underlying: Common Stock · 3,076 shares

Expires 2027-07-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: All shares underlying this option were fully vested as of July 6, 2017.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
SaleCommon Stock 3,076 $17.62 $54,203.73
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 2

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,817

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

Read SEC document
July 05, 2018 Filed Jul 7, 2018 01:41 UTC
Mahadevia AnkitDirector · See Remarks
Exercise / conversionCommon Stock 3,076 $5.90 $18,148.40
Disclosure

SEC source: 0000899243-18-019566 · doc4.xml · nonDerivative · entry 1

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,893

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and related sales (totaling 4,676 shares) reported in this Form 4 were made pursuant to a Rule 10b5-1 trading plan previously entered into by the Reporting Person in December 2017.

F2 · balance_after: Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee.

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June 05, 2018 Filed Jun 7, 2018 00:01 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $11.54 $0.00
Disclosure

SEC source: 0000899243-18-015329 · doc4.xml · derivative · entry 1

FORMELA JEAN FRANCOIS · CIK 0001030575 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2028-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2019, subject to the Reporting Person's continued service as a director through the vesting date.

F2 · ownership.direct: The reporting person is a member of Atlas Venture Associates IX, LLC ("AVA IX LLC") and is obligated to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the equity grants to Atlas Venture Advisors, L.P. As such, the Reporting Person disclaims beneficial ownership of the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

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June 05, 2018 Filed Jun 7, 2018 00:02 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $11.54 $0.00
Disclosure

SEC source: 0000899243-18-015330 · doc4.xml · derivative · entry 1

THOMAS FRANK E · CIK 0001242616 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2028-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2019, subject to the Reporting Person's continued service as a director through the vesting date.

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June 05, 2018 Filed Jun 7, 2018 00:01 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $11.54 $0.00
Disclosure

SEC source: 0000899243-18-015328 · doc4.xml · derivative · entry 1

SOUTHWELL DAVID P · CIK 0001251553 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2028-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2019, subject to the Reporting Person's continued service as a director through the vesting date.

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June 05, 2018 Filed Jun 7, 2018 00:00 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $11.54 $0.00
Disclosure

SEC source: 0000899243-18-015326 · doc4.xml · derivative · entry 1

Deshpande Milind · CIK 0001378588 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2028-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2019, subject to the Reporting Person's continued service as a director through the vesting date.

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June 05, 2018 Filed Jun 7, 2018 00:01 UTC
Breum CasperDirector
GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $11.54 $0.00
Disclosure

SEC source: 0000899243-18-015327 · doc4.xml · derivative · entry 1

Breum Casper · CIK 0001630850 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2028-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2019, subject to the Reporting Person's continued service as a director through the vesting date.

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June 05, 2018 Filed Jun 7, 2018 00:00 UTC GrantStock Option (right to buy) · Derivative 6,073 $0.00 Strike: $11.54 $0.00
Disclosure

SEC source: 0000899243-18-015325 · doc4.xml · derivative · entry 1

VINK PATRICK V.J.J. · CIK 0001557501 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,073

Underlying: Common Stock · 6,073 shares

Expires 2028-06-05

F1 · derivative.exercise_date: The shares underlying this option will vest and become exercisable in full on June 5, 2019, subject to the Reporting Person's continued service as a director through the vesting date.

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March 30, 2018 Filed Mar 30, 2018 21:30 UTC GrantStock Option (right to buy) · Derivative 12,146 $0.00 Strike: $14.25 $0.00
Disclosure

SEC source: 0000899243-18-008989 · doc4.xml · derivative · entry 1

SOUTHWELL DAVID P · CIK 0001251553 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,146

Underlying: Common Stock · 12,146 shares

Expires 2028-03-30

F1 · derivative.exercise_date: The shares underlying this option will vest in thirty-six equal monthly installments at the end of each successive month following March 30, 2018, subject to the Reporting Person's continued service as a director through the applicable vesting dates.

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January 04, 2018 Filed Jan 5, 2018 15:11 UTC
Melnick David A.Chief Medical Officer
GrantStock Option (Right to Buy) · Derivative 135,000 $0.00 Strike: $12.14 $0.00
Disclosure

SEC source: 0000899243-18-000561 · doc4.xml · derivative · entry 1

Melnick David A. · CIK 0001726485 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 135,000

Underlying: Common Stock · 135,000 shares

Expires 2028-01-03

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on January 4, 2019, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

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December 13, 2017 Filed Dec 15, 2017 21:07 UTC
Larkin CristinaChief Operating Officer
GrantStock Option (Right to Buy) · Derivative 62,540 $0.00 Strike: $11.63 $0.00
Disclosure

SEC source: 0000899243-17-028851 · doc4.xml · derivative · entry 1

Larkin Cristina · CIK 0001721173 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,540

Underlying: Common Stock · 62,540 shares

Expires 2027-12-12

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on December 13, 2018, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

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December 13, 2017 Filed Dec 15, 2017 21:06 UTC
Sendek JoelChief Financial Officer
GrantStock Option (Right to Buy) · Derivative 27,795 $0.00 Strike: $11.63 $0.00
Disclosure

SEC source: 0000899243-17-028850 · doc4.xml · derivative · entry 1

Sendek Joel · CIK 0001720875 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,795

Underlying: Common Stock · 27,795 shares

Expires 2027-12-12

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on December 13, 2018, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

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December 13, 2017 Filed Dec 15, 2017 21:05 UTC
Parr Thomas R JRChief Scientific Officer
GrantStock Option (Right to Buy) · Derivative 36,134 $0.00 Strike: $11.63 $0.00
Disclosure

SEC source: 0000899243-17-028848 · doc4.xml · derivative · entry 1

Parr Thomas R JR · CIK 0001413008 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,134

Underlying: Common Stock · 36,134 shares

Expires 2027-12-12

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on December 13, 2018, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

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December 13, 2017 Filed Dec 15, 2017 21:05 UTC
Mahadevia AnkitDirector · See Remarks
GrantStock Option (Right to Buy) · Derivative 125,079 $0.00 Strike: $11.63 $0.00
Disclosure

SEC source: 0000899243-17-028846 · doc4.xml · derivative · entry 1

Mahadevia Ankit · CIK 0001720974 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,079

Underlying: Common Stock · 125,079 shares

Expires 2027-12-12

F1 · derivative.exercise_date: The shares underlying this option vest as to 25% on December 13, 2018, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through the applicable vesting date.

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November 06, 2017 Filed Nov 7, 2017 21:08 UTC ConversionSeries C Preferred Stock · Derivative 3,662,178 $0.00 $0.00
Disclosure

SEC source: 0000899243-17-025510 · doc4.xml · derivative · entry 11

FORMELA JEAN FRANCOIS · CIK 0001030575 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 602,589 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Amount of underlying securities reflects the application of the applicable conversion ratio as set forth in the Issuer's Amended and Restated Certificate of Incorporation in effect immediately prior to the closing of the initial public offering (as adjusted by the 1-for-6.0774 reverse stock split of the Issuer's common stock effected on October 20, 2017). Each series of preferred stock was automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration and had no expiration date.

F2 · derivative.exercise_date: Amount of underlying securities reflects the application of the applicable conversion ratio as set forth in the Issuer's Amended and Restated Certificate of Incorporation in effect immediately prior to the closing of the initial public offering (as adjusted by the 1-for-6.0774 reverse stock split of the Issuer's common stock effected on October 20, 2017). Each series of preferred stock was automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration and had no expiration date.

F2 · derivative.expiration_date: Amount of underlying securities reflects the application of the applicable conversion ratio as set forth in the Issuer's Amended and Restated Certificate of Incorporation in effect immediately prior to the closing of the initial public offering (as adjusted by the 1-for-6.0774 reverse stock split of the Issuer's common stock effected on October 20, 2017). Each series of preferred stock was automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration and had no expiration date.

F4 · ownership.nature: Shares held by Atlas Venture Fund X, L.P. ("Atlas Venture Fund X"). The general partner of Atlas Venture Fund X is Atlas Venture Associates X, L.P. ("AVA X LP"). Atlas Venture Associates X, LLC ("AVA X LLC") is the general partner of AVA X LP. Dr. Formela is a member of AVA X LLC and disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein, if any.

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November 06, 2017 Filed Nov 7, 2017 21:08 UTC ConversionSeries C Preferred Stock · Derivative 3,119,633 $0.00 $0.00
Disclosure

SEC source: 0000899243-17-025510 · doc4.xml · derivative · entry 10

FORMELA JEAN FRANCOIS · CIK 0001030575 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 513,318 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Amount of underlying securities reflects the application of the applicable conversion ratio as set forth in the Issuer's Amended and Restated Certificate of Incorporation in effect immediately prior to the closing of the initial public offering (as adjusted by the 1-for-6.0774 reverse stock split of the Issuer's common stock effected on October 20, 2017). Each series of preferred stock was automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration and had no expiration date.

F2 · derivative.exercise_date: Amount of underlying securities reflects the application of the applicable conversion ratio as set forth in the Issuer's Amended and Restated Certificate of Incorporation in effect immediately prior to the closing of the initial public offering (as adjusted by the 1-for-6.0774 reverse stock split of the Issuer's common stock effected on October 20, 2017). Each series of preferred stock was automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration and had no expiration date.

F2 · derivative.expiration_date: Amount of underlying securities reflects the application of the applicable conversion ratio as set forth in the Issuer's Amended and Restated Certificate of Incorporation in effect immediately prior to the closing of the initial public offering (as adjusted by the 1-for-6.0774 reverse stock split of the Issuer's common stock effected on October 20, 2017). Each series of preferred stock was automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration and had no expiration date.

F3 · ownership.nature: Shares held by Atlas Venture Fund IX, L.P. ("Atlas Venture Fund IX"). The general partner of Atlas Venture Fund IX is Atlas Venture Associates IX, L.P. ("AVA IX LP"). Atlas Venture Associates IX, LLC ("AVA IX LLC") is the general partner of AVA IX LP. Dr. Formela is a member of AVA IX LLC and disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein, if any.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.