SLDB

SEC source: 0001209191-20-005404 · doc4.xml · derivative · entry 2

Ganot Ilan · CIK 0001727460 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,000

Underlying: Common Stock · 71,000 shares

Expires 2030-01-27

F2 · derivative.exercise_date: The restricted stock units will vest in 2 installments. Fifty percent will vest six months after the grant date with the remaining fifty percent vesting on the first anniversary of the grant date and will vest automatically as to 100% of the unvested portion of such restricted stock unit grant upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005404 · doc4.xml · derivative · entry 1

Ganot Ilan · CIK 0001727460 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,000

Underlying: Common Stock · 142,000 shares

Expires 2030-01-27

F1 · derivative.exercise_date: This option was granted on January 27, 2020 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005410 · doc4.xml · derivative · entry 2

Morris Carl Ashley · CIK 0001727571 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,000

Underlying: Common Stock · 23,000 shares

Expires 2030-01-27

F2 · derivative.exercise_date: The restricted stock units will vest in 2 installments. Fifty percent will vest six months after the grant date with the remaining fifty percent vesting on the first anniversary of the grant date and will vest automatically as to 100% of the unvested portion of such restricted stock unit grant upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005410 · doc4.xml · derivative · entry 1

Morris Carl Ashley · CIK 0001727571 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,000

Underlying: Common Stock · 47,000 shares

Expires 2030-01-27

F1 · derivative.exercise_date: This option was granted on January 27, 2020 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005414 · doc4.xml · derivative · entry 2

Ziolkowski Jennifer Lynn · CIK 0001727410 · CFO, Treasurer & Asst. Secy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,000

Underlying: Common Stock · 23,000 shares

Expires 2030-01-27

F2 · derivative.exercise_date: The restricted stock units will vest in 2 installments. Fifty percent will vest six months after the grant date with the remaining fifty percent vesting on the first anniversary of the grant date and will vest automatically as to 100% of the unvested portion of such restricted stock unit grant upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005414 · doc4.xml · derivative · entry 1

Ziolkowski Jennifer Lynn · CIK 0001727410 · CFO, Treasurer & Asst. Secy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,000

Underlying: Common Stock · 47,000 shares

Expires 2030-01-27

F1 · derivative.exercise_date: This option was granted on January 27, 2020 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005412 · doc4.xml · derivative · entry 2

Schneider Joel Solomon Zev · CIK 0001727649 · Chief Technology Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,000

Underlying: Common Stock · 23,000 shares

Expires 2030-01-27

F2 · derivative.exercise_date: The restricted stock units will vest in 2 installments. Fifty percent will vest six months after the grant date with the remaining fifty percent vesting on the first anniversary of the grant date and will vest automatically as to 100% of the unvested portion of such restricted stock unit grant upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-005412 · doc4.xml · derivative · entry 1

Schneider Joel Solomon Zev · CIK 0001727649 · Chief Technology Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,000

Underlying: Common Stock · 47,000 shares

Expires 2030-01-27

F1 · derivative.exercise_date: This option was granted on January 27, 2020 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0001209191-20-008909 · doc4a.xml · derivative · entry 1

Ganot Ilan · CIK 0001727460 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Indirect · Wife

Disclosed balance after: 4,320

Underlying: Common Stock · 4,320 shares

Expires 2030-01-27

F1 · security: This amendment to the Form 4 filed on January 29, 2020 (the "Original Form 4") is being filed to add a transaction inadvertently omitted from the Original Form 4. The Original Form 4 omitted an option grant to the reporting person's wife.

F2 · derivative.exercise_date: This option was granted on January 27, 2020 and vests in four equal annual installments on the anniversary of the grant date.

SEC source: 0001209191-20-000997 · doc4.xml · derivative · entry 1

Zarur Juan Andrey · CIK 0001727404 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2030-01-02

F1 · derivative.exercise_date: This option was granted on January 2, 2020 and vests in full on December 31, 2020.

SEC source: 0001209191-19-045880 · doc4.xml · derivative · entry 1

Ganot Ilan · CIK 0001727460 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Indirect · Wife

Disclosed balance after: 1,600

Underlying: Common Stock · 1,600 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Solid Biosciences Inc. common stock.

F2 · derivative.exercise_date: The restricted stock units vest in two equal installments on February 12, 2020 and August 12, 2020. Vested shares will be delivered to the reporting person on the applicable vesting date.

F2 · derivative.expiration_date: The restricted stock units vest in two equal installments on February 12, 2020 and August 12, 2020. Vested shares will be delivered to the reporting person on the applicable vesting date.

SEC source: 0000899243-19-020588 · doc4.xml · nonDerivative · entry 1

Koppel Adam · CIK 0001578965 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,871,164

F3 · kind: On July 30, 2019, BCLS purchased 1,881,720 shares of common stock directly from the Issuer at a price per share of $4.65.

F3 · shares: On July 30, 2019, BCLS purchased 1,881,720 shares of common stock directly from the Issuer at a price per share of $4.65.

F1 · ownership.nature: Represents shares of common stock held directly by BCLS SB Investco, LP ("BCLS").

F2 · ownership.nature: Bain Capital Life Sciences Investors, LLC, whose managers are Jeffrey Schwartz and Adam Koppel, is the general partner of Bain Capital Life Sciences Partners, LP, which is the general partner of BCLS. As a result, Dr. Koppel may be deemed to share voting and dispositive power with respect to the shares of common stock held by BCLS. Dr. Koppel disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001012975-19-000502 · edgar.xml · nonDerivative · entry 1

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · Director · 10% owner

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD · CIK 0001249675 · Director · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 6,749,803

F1 · ownership.nature: The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-19-043485 · doc4.xml · nonDerivative · entry 1

Morris Carl Ashley · CIK 0001727571 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,050

SEC source: 0001209191-19-043483 · doc4.xml · nonDerivative · entry 1

Ganot Ilan · CIK 0001727460 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,123,631

F1 · ownership.direct: Represents 1,063,000 shares held by Mr. Ganot as an individual. Represents 60,631 shares held by Mr. Ganot and Annie Ganot as joint tenants with a right of survivorship.

SEC source: 0001209191-19-043491 · doc4.xml · nonDerivative · entry 1

Shah Rajeev M. · CIK 0001619841 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,571,164

F1 · shares: Includes 1,593,629 shares of Common Stock that are held by RA Capital Healthcare Fund, L.P. (the "Fund") and 288,091 shares of Common Stock that are held in an account owned by a separately managed account (the "Account").

F2 · balance_after: Following the reported transaction, the Fund held 3,771,600 shares and the Account held 799,564 shares.

F3 · ownership.direct: RA Capital Management, LLC (the "Adviser") is the general partner of the Fund and the investment adviser of the Account. Peter Kolchinsky is the sole manager of the Adviser, and Mr. Shah is a member of the Adviser. Mr. Shah has no pecuniary interest in the reported securities held in the Account and therefore disclaims beneficial ownership of those securities. Mr. Shah disclaims beneficial ownership of the reported securities held by the Fund except to the extent of his pecuniary interest therein.

SEC source: 0001209191-19-043487 · doc4.xml · nonDerivative · entry 1

Nagendran Sukumar · CIK 0001665124 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,258

SEC source: 0001209191-19-043481 · doc4.xml · nonDerivative · entry 1

Freed Martin I · CIK 0001676653 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,763

SEC source: 0001209191-19-043479 · doc4.xml · nonDerivative · entry 1

Arnold Matthew Bennett · CIK 0001727991 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,500,997

SEC source: 0001209191-19-041954 · doc4.xml · nonDerivative · entry 1

Arnold Matthew Bennett · CIK 0001727991 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,823,578

SEC source: 0001209191-19-037124 · doc4.xml · derivative · entry 1

Shah Rajeev M. · CIK 0001619841 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

F2 · ownership.direct: Under the Reporting Person's arrangement with RA Capital Management, LLC (the "Manager"), the Reporting Person holds the option for the benefit for the benefit of RA Capital Healthcare Fund, L.P. (the "Fund") and a separately managed account (the "Account"). The Reporting Person is obligated to turn over to the Manager any net cash or stock received upon exercise of the option, which will offset advisory fees owed by the Fund and Account to the Manager. The Reporting Person therefore disclaims beneficial ownership of the option and underlying common stock.

SEC source: 0001209191-19-037122 · doc4.xml · derivative · entry 1

Huffines Robert Luther · CIK 0001728221 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0001209191-19-037130 · doc4.xml · derivative · entry 1

Zarur Juan Andrey · CIK 0001727404 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0001209191-19-037127 · doc4.xml · derivative · entry 1

Sullivan Lynne Marie · CIK 0001727640 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0001209191-19-037123 · doc4.xml · derivative · entry 1

Nagendran Sukumar · CIK 0001665124 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0001209191-19-037121 · doc4.xml · derivative · entry 1

Freed Martin I · CIK 0001676653 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0001209191-19-037117 · doc4.xml · derivative · entry 1

Arnold Matthew Bennett · CIK 0001727991 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0000899243-19-017135 · doc4.xml · derivative · entry 1

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · Director · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of June 13, 2020 and immediately prior to the Issuer's first annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

F2 · ownership.nature: Consists of options to purchase shares of the Issuer's common stock awarded to Adam Stone in connection with his role as a member of the Issuer's Board of Directors. Mr. Stone is the Chief Investment Officer of Perceptive Advisors, LLC (the "Advisor"). The Advisor may be deemed to have an indirect pecuniary interest in the options to purchase common stock of the Issuer reported herein because the Advisor has the right to receive the director compensation provided in respect of Mr. Stone's board service through a partial management fee offset.

F3 · ownership.nature: (Continued from footnote 2) Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

SEC source: 0000899243-19-017134 · doc4.xml · derivative · entry 1

Stone Adam Leo · CIK 0001727440 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of June 13, 2020 and immediately prior to the Issuer's first annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0000899243-19-017188 · doc4.xml · derivative · entry 1

Koppel Adam · CIK 0001578965 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's first annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0000899243-19-013080 · doc4.xml · nonDerivative · entry 1

Zarur Juan Andrey · CIK 0001727404 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 10,189

F1 · shares: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person's spouse on March 15, 2019.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.02, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote (2) to this Form.

SEC source: 0000899243-19-009195 · doc4.xml · nonDerivative · entry 3

Boxer Capital, LLC · CIK 0001465837 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,473,272

F4 · price: Reflects the weighted average sale price. The reporting person effected multiple same-way open market sale transactions on the same day at different prices through a trade order executed by a broker dealer. The reporting person reported on a single line all such transactions that occurred within a one dollar price range. The reporting person hereby undertakes to provide upon request by the Securities and Exchange Commission staff, the issuer, or a shareholder of the issuer, full information regarding the number of shares sold at each separate price. The range of prices for such transaction is $9.52 to $9.55.

F1 · ownership.direct: These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc. ("Boxer Management"), (iii) Braslyn Ltd., (iv) Joseph C. Lewis and (v) MVA Investors, LLC (collectively, the "Boxer Group"), and indirectly by Boxer Management and Mr. Lewis. Each member of the Boxer Group other than Boxer Capital disclaims beneficial ownership of these securities to the extent it does not have a pecuniary interest therein.

SEC source: 0000899243-19-009195 · doc4.xml · nonDerivative · entry 2

Boxer Capital, LLC · CIK 0001465837 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,533,272

F3 · price: Reflects the weighted average sale price. The reporting person effected multiple same-way open market sale transactions on the same day at different prices through a trade order executed by a broker dealer. The reporting person reported on a single line all such transactions that occurred within a one dollar price range. The reporting person hereby undertakes to provide upon request by the Securities and Exchange Commission staff, the issuer, or a shareholder of the issuer, full information regarding the number of shares sold at each separate price. The range of prices for such transaction is $9.53 to $9.80.

F1 · ownership.direct: These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc. ("Boxer Management"), (iii) Braslyn Ltd., (iv) Joseph C. Lewis and (v) MVA Investors, LLC (collectively, the "Boxer Group"), and indirectly by Boxer Management and Mr. Lewis. Each member of the Boxer Group other than Boxer Capital disclaims beneficial ownership of these securities to the extent it does not have a pecuniary interest therein.

SEC source: 0000899243-19-009195 · doc4.xml · nonDerivative · entry 1

Boxer Capital, LLC · CIK 0001465837 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,648,272

F2 · price: Reflects the weighted average sale price. The reporting person effected multiple same-way open market sale transactions on the same day at different prices through a trade order executed by a broker dealer. The reporting person reported on a single line all such transactions that occurred within a one dollar price range. The reporting person hereby undertakes to provide upon request by the Securities and Exchange Commission staff, the issuer, or a shareholder of the issuer, full information regarding the number of shares sold at each separate price. The range of prices for such transaction is $10.00 to $10.13.

F1 · ownership.direct: These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc. ("Boxer Management"), (iii) Braslyn Ltd., (iv) Joseph C. Lewis and (v) MVA Investors, LLC (collectively, the "Boxer Group"), and indirectly by Boxer Management and Mr. Lewis. Each member of the Boxer Group other than Boxer Capital disclaims beneficial ownership of these securities to the extent it does not have a pecuniary interest therein.

SEC source: 0000899243-19-004375 · doc4.xml · derivative · entry 1

HERSCHA LYNETTE · CIK 0001708198 · See Remark

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2029-02-19

F1 · derivative.exercise_date: This option was granted February 19, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0000899243-19-001959 · doc4.xml · derivative · entry 1

Ganot Ilan · CIK 0001727460 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,000

Underlying: Common Stock · 155,000 shares

Expires 2029-01-23

F1 · derivative.exercise_date: This option was granted on January 23, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0000899243-19-001957 · doc4.xml · derivative · entry 1

Morris Carl Ashley · CIK 0001727571 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2029-01-23

F1 · derivative.exercise_date: This option was granted on January 23, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0000899243-19-001960 · doc4.xml · derivative · entry 1

Quiroz Jorge Armando · CIK 0001727401 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2029-01-23

F1 · derivative.exercise_date: This option was granted on January 23, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0000899243-19-001956 · doc4.xml · derivative · entry 1

Ziolkowski Jennifer Lynn · CIK 0001727410 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2029-01-23

F1 · derivative.exercise_date: This option was granted on January 23, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0000899243-19-001955 · doc4.xml · derivative · entry 1

Amorrortu Pedro Alvaro · CIK 0001727552 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2029-01-23

F1 · derivative.exercise_date: This option was granted on January 23, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0000899243-19-001954 · doc4.xml · derivative · entry 1

Schneider Joel Solomon Zev · CIK 0001727649 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2029-01-23

F1 · derivative.exercise_date: This option was granted on January 23, 2019 and vests in four equal annual installments on the anniversary of the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events and the termination of the Reporting Person's employment under specified circumstances.

SEC source: 0000899243-19-001270 · doc4.xml · nonDerivative · entry 2

Arnold Matthew Bennett · CIK 0001727991 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,386,293

F1 · shares: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 5, 2018.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.00 to $32.75, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) to this Form.

SEC source: 0000899243-19-001270 · doc4.xml · nonDerivative · entry 1

Arnold Matthew Bennett · CIK 0001727991 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,389,593

F1 · shares: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 5, 2018.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.05 to $32.00, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form.

SEC source: 0000899243-19-000742 · doc4.xml · nonDerivative · entry 1

Arnold Matthew Bennett · CIK 0001727991 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,391,293

F1 · shares: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 5, 2018.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.00 to $30.36, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form.

SEC source: 0000899243-19-000739 · doc4.xml · nonDerivative · entry 1

Amorrortu Pedro Alvaro · CIK 0001727552 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,046

F1 · shares: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2018.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.00 to $30.19, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form.

SEC source: 0000899243-19-000970 · doc4a.xml · nonDerivative · entry 1

Amorrortu Pedro Alvaro · CIK 0001727552 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 153,746

F1 · shares: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2018.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.00 to $30.19, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form.

F3 · balance_after: Amendment corrects arithmetical error as to number of securities in Column 5 of Table I.

SEC source: 0000899243-19-000269 · doc4.xml · derivative · entry 2

Zarur Juan Andrey · CIK 0001727404 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2029-01-02

F2 · derivative.exercise_date: This option was granted on January 2, 2019 and vests in four equal consecutive annual installments beginning January 2, 2020.

SEC source: 0000899243-19-000269 · doc4.xml · derivative · entry 1

Zarur Juan Andrey · CIK 0001727404 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2029-01-02

F1 · derivative.exercise_date: This option was granted on January 2, 2019 and vests in full on the one year anniversary of the grant date.

SEC source: 0000899243-18-031207 · doc4.xml · derivative · entry 1

Zarur Juan Andrey · CIK 0001727404 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-12-13

F1 · derivative.exercise_date: This option was granted on December 13, 2018 and vests in full on the earlier to occur of the one year anniversary of the grant date and immediately prior to the Issuer's first annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.

SEC source: 0000899243-18-031204 · doc4.xml · derivative · entry 1

Nagendran Sukumar · CIK 0001665124 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,240

Underlying: Common Stock · 17,240 shares

Expires 2028-12-13

F1 · derivative.exercise_date: This option was granted on December 13, 2018 and vests as to one-third of the total number of shares on each of September 12, 2019, September 12, 2020, and September 12, 2021, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events.