SIBN

SEC source: 0001562180-21-001288 · primarydocument.xml · derivative · entry 4

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,913

Underlying: Common Stock · 2,125 shares

Expires 2026-07-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The shares subject to the option vest in equal monthly installments over four years commencing on vesting commencement date, subject to Reporting Person's continued service through each relevant vesting date.

SEC source: 0001562180-21-001288 · primarydocument.xml · nonDerivative · entry 3

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,459

F2 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F3 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $30.77 to $31.23, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F4 · balance_after: Includes 57,759 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-001288 · primarydocument.xml · nonDerivative · entry 2

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,584

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001562180-21-001288 · primarydocument.xml · nonDerivative · entry 1

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,459

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-21-001009 · primarydocument.xml · derivative · entry 6

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,150

Underlying: Common Stock · 9,839 shares

Expires 2025-05-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The shares subject to the option vest in equal monthly installments over four years commencing on vesting commencement date, subject to Reporting Person's continued service through each relevant vesting date.

SEC source: 0001562180-21-001009 · primarydocument.xml · nonDerivative · entry 4

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,616

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F3 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $33.00 to $33.34, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F4 · balance_after: Includes 121,456 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-001009 · primarydocument.xml · nonDerivative · entry 3

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 190,455

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001562180-21-001010 · primarydocument.xml · nonDerivative · entry 2

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 75,940

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F3 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $33.04 to $33.19, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F4 · balance_after: Shares held by The Jeffrey W. Dunn Living Trust Dated May 17, 2012.

SEC source: 0001562180-21-001010 · primarydocument.xml · nonDerivative · entry 1

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 76,559

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $31.97 to $32.94, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

SEC source: 0001562180-21-001009 · primarydocument.xml · derivative · entry 5

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,989

Underlying: Common Stock · 803 shares

Expires 2025-05-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The shares subject to the option vest in equal monthly installments over four years commencing on vesting commencement date, subject to Reporting Person's continued service through each relevant vesting date.

SEC source: 0001562180-21-001009 · primarydocument.xml · nonDerivative · entry 2

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,616

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $33.00 to $33.23, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

SEC source: 0001562180-21-001009 · primarydocument.xml · nonDerivative · entry 1

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 181,419

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001562180-21-000574 · primarydocument.xml · derivative · entry 3

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,792

Underlying: Common Stock · 600 shares

Expires 2025-05-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The shares subject to the option vest in equal monthly installments over four years commencing on vesting commencement date, subject to Reporting Person's continued service through each relevant vesting date.

SEC source: 0001562180-21-000574 · primarydocument.xml · nonDerivative · entry 2

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,616

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $33.00 to $33.05, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F3 · balance_after: Includes 121,456 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000574 · primarydocument.xml · nonDerivative · entry 1

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 181,216

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001562180-21-000437 · primarydocument.xml · nonDerivative · entry 2

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 340,610

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 273,175 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000437 · primarydocument.xml · nonDerivative · entry 1

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 342,427

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-21-000438 · primarydocument.xml · nonDerivative · entry 2

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,509

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 101,356 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000438 · primarydocument.xml · nonDerivative · entry 1

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,540

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-21-000436 · primarydocument.xml · nonDerivative · entry 2

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,143

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 59,786 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000436 · primarydocument.xml · nonDerivative · entry 1

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,760

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-21-000257 · primarydocument.xml · nonDerivative · entry 3

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 115,940

F3 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F6 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $29.03 to $29.64, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F5 · ownership.nature: Shares held by The Jeffrey W. Dunn Living Trust Dated May 17, 2012.

SEC source: 0001562180-21-000257 · primarydocument.xml · nonDerivative · entry 2

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 131,195

F3 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F4 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $28.03 to $29.02, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F5 · ownership.nature: Shares held by The Jeffrey W. Dunn Living Trust Dated May 17, 2012.

SEC source: 0001562180-21-000257 · primarydocument.xml · nonDerivative · entry 1

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 343,878

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest over four years beginning on January 1, 2021 and will be released in quarterly installments commencing on May 15, 2021, subject to the Reporting Person's continued service through each relevant vesting date.

F2 · balance_after: Includes 281,931 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000255 · primarydocument.xml · nonDerivative · entry 1

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,053

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest over four years beginning on January 1, 2021 and will be released in quarterly installments commencing on May 15, 2021, subject to the Reporting Person's continued service through each relevant vesting date.

F2 · balance_after: Includes 61,998 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000254 · primarydocument.xml · nonDerivative · entry 1

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,162

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest over four years beginning on January 1, 2021 and will be released in quarterly installments commencing on May 15, 2021, subject to the Reporting Person's continued service through each relevant vesting date.

F2 · balance_after: Includes 106,337 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-21-000253 · primarydocument.xml · nonDerivative · entry 1

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,616

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest over four years beginning on January 1, 2021 and will be released in quarterly installments commencing on May 15, 2021, subject to the Reporting Person's continued service through each relevant vesting date.

F2 · balance_after: Includes 121,456 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-007363 · primarydocument.xml · derivative · entry 5

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,190

Underlying: Common Stock · 3,000 shares

Expires 2026-07-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The shares subject to the option vest in equal monthly installments over four years commencing on vesting commencement date, subject to Reporting Person's continued service through each relevant vesting date.

SEC source: 0001562180-20-007363 · primarydocument.xml · nonDerivative · entry 4

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,882

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F4 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $29.72 to $30.15, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F5 · balance_after: Includes 57,057 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-007363 · primarydocument.xml · nonDerivative · entry 3

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,810

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F3 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $27.72 to $28.08, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

SEC source: 0001562180-20-007363 · primarydocument.xml · nonDerivative · entry 2

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,010

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $28.72 to $29.69, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

SEC source: 0001562180-20-007363 · primarydocument.xml · nonDerivative · entry 1

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,882

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001562180-20-007132 · primarydocument.xml · nonDerivative · entry 2

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 155,940

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F4 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $24.05 to $25.0499, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F3 · ownership.nature: Shares held by The Jeffrey W. Dunn Living Trust Dated May 17, 2012.

SEC source: 0001562180-20-007132 · primarydocument.xml · nonDerivative · entry 1

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 185,988

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $23.02 to $24.0199, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F3 · ownership.nature: Shares held by The Jeffrey W. Dunn Living Trust Dated May 17, 2012.

SEC source: 0001562180-20-007090 · primarydocument.xml · nonDerivative · entry 2

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Skyline Venture Partners V, LP

Disclosed balance after: 1,482,046

F3 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $22.95 to $23.6950, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

F4 · balance_after: Reflects a previous pro rata distribution by Skyline Venture Partners V, L.P. ("SVP V") of 500,000 shares, for no consideration.

F2 · ownership.nature: Shares held by SVP V. Skyline Venture Management V, LLC ("LLC") is the general partner of SVP V and as such may be deemed to have voting and investment power with respect to the securities of SVP V. Reporting Person, a member of Issuer's board of directors, is a managing director of LLC and may be deemed to have voting and investment power with respect to the securities held by SVP V. Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein.

SEC source: 0001562180-20-007090 · primarydocument.xml · nonDerivative · entry 1

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Skyline Venture Partners V, LP

Disclosed balance after: 1,529,932

F1 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $22.45 to $23.43, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: Shares held by SVP V. Skyline Venture Management V, LLC ("LLC") is the general partner of SVP V and as such may be deemed to have voting and investment power with respect to the securities of SVP V. Reporting Person, a member of Issuer's board of directors, is a managing director of LLC and may be deemed to have voting and investment power with respect to the securities held by SVP V. Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein.

SEC source: 0001562180-20-006780 · primarydocument.xml · nonDerivative · entry 1

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 217,878

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 155,931 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · balance_after: Includes 1,441 shares acquired under the SI-BONE, Inc. 2018 Employee Stock Purchase Plan on November 13, 2020

SEC source: 0001562180-20-006782 · primarydocument.xml · nonDerivative · entry 1

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,882

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 57,057 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-006783 · primarydocument.xml · nonDerivative · entry 1

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,303

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 33,248 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-006781 · primarydocument.xml · nonDerivative · entry 4

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,336

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 72,176 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-006781 · primarydocument.xml · nonDerivative · entry 3

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,044

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-20-006781 · primarydocument.xml · nonDerivative · entry 2

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,963

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-20-006781 · primarydocument.xml · nonDerivative · entry 1

FRANCIS LAURA · CIK 0001218802 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,584

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-20-006394 · primarydocument.xml · nonDerivative · entry 2

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 220,930

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 164,981 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-006399 · primarydocument.xml · nonDerivative · entry 1

Freund John Gordon · CIK 0001296771 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Skyline Venture Partners V, L.P.

Disclosed balance after: 2,129,932

F1 · kind: Shares were sold in conjunction with the Issuer's public offering of common stock announced on October 14, 2020.

F2 · ownership.nature: Shares held by Skyline Venture Partners V, L.P. ("SVP V"). Skyline Venture Management V, LLC ("LLC") is the general partner of SVP V and as such may be deemed to have voting and investment power with respect to the securities of SVP V. Reporting Person, a member of Issuer's board of directors, is a managing director of LLC and may be deemed to have voting and investment power with respect to the securities held by SVP V. Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein.

SEC source: 0001562180-20-006394 · primarydocument.xml · nonDerivative · entry 1

DUNN JEFFREY W · CIK 0001035986 · Director · Chairman, President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,204

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001562180-20-006393 · primarydocument.xml · nonDerivative · entry 1

RECUPERO ANTHONY J · CIK 0001210230 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,492

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 60,435 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-006392 · primarydocument.xml · nonDerivative · entry 1

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,005

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale satisfies the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 35,275 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-20-006073 · primarydocument.xml · derivative · entry 3

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,038

Underlying: Common Stock · 3,000 shares

Expires 2026-07-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The shares subject to the option vest in equal monthly installments over four years commencing on vesting commencement date, subject to Reporting Person's continued service through each relevant vesting date.

SEC source: 0001562180-20-006073 · primarydocument.xml · nonDerivative · entry 2

Pisetsky Michael A · CIK 0001754765 · GC & Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,252

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · balance_after: Includes 35,988 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.