RPID

SEC source: 0001127602-22-009388 · form4.xml · derivative · entry 2

Spignesi Robert G. Jr. · CIK 0001853904 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 139,964

Underlying: Class A Common Stock · 35,000 shares

Expires 2027-10-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option was originally granted for 224,964 shares and vested and became exercisable in 48 substantially equal monthly installments with the first installment vesting on November 12, 2017.

SEC source: 0001127602-22-009388 · form4.xml · nonDerivative · entry 1

Spignesi Robert G. Jr. · CIK 0001853904 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 184,027

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-22-009198 · form4.xml · nonDerivative · entry 1

LOWENSTEIN INESE · CIK 0001900476 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

SEC source: 0001127602-22-005151 · form4.xml · derivative · entry 2

KEYS RICHARD A · CIK 0001886207 · CHIEF COMMERCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,500

Underlying: Class A Common Stock · 87,500 shares

Expires 2032-02-10

F2 · derivative.exercise_date: The option vests and becomes exercisable in 48 substantially equal monthly installments with the first installment vesting on March 11, 2022.

SEC source: 0001127602-22-005151 · form4.xml · nonDerivative · entry 1

KEYS RICHARD A · CIK 0001886207 · CHIEF COMMERCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,750

F1 · shares: Grant of restricted stock units ("RSUs") that vest in three annual installments with 33.4% vesting on the first anniversary of February 11, 2022 (the "grant date") and 33.3% vesting on each of the second and third anniversaries of the grant date provided that the Reporting Person remains in continuous service on each vesting date.

SEC source: 0001127602-22-005161 · form4.xml · derivative · entry 2

Wilson John J. Addington · CIK 0001872301 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,500

Underlying: Class A Common Stock · 122,500 shares

Expires 2032-02-10

F2 · derivative.exercise_date: The option vests and becomes exercisable in 48 substantially equal monthly installments with the first installment vesting on March 11, 2022.

SEC source: 0001127602-22-005161 · form4.xml · nonDerivative · entry 1

Wilson John J. Addington · CIK 0001872301 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,250

F1 · shares: Grant of restricted stock units ("RSUs") that vest in three annual installments with 33.4% vesting on the first anniversary of February 11, 2022 (the "grant date") and 33.3% vesting on each of the second and third anniversaries of the grant date provided that the Reporting Person remains in continuous service on each vesting date.

SEC source: 0001127602-22-005155 · form4.xml · derivative · entry 2

Paris Jonathan · CIK 0001866482 · Senior VP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,500

Underlying: Class A Common Stock · 87,500 shares

Expires 2032-02-10

F2 · derivative.exercise_date: The option vests and becomes exercisable in 48 substantially equal monthly installments with the first installment vesting on March 11, 2022.

SEC source: 0001127602-22-005155 · form4.xml · nonDerivative · entry 1

Paris Jonathan · CIK 0001866482 · Senior VP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,750

F1 · shares: Grant of restricted stock units ("RSUs") that vest in three annual installments with 33.4% vesting on the first anniversary of February 11, 2022 (the "grant date") and 33.3% vesting on each of the second and third anniversaries of the grant date provided that the Reporting Person remains in continuous service on each vesting date.

SEC source: 0001127602-22-005152 · form4.xml · derivative · entry 2

Spignesi Robert G. Jr. · CIK 0001853904 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 197,500

Underlying: Class A Common Stock · 197,500 shares

Expires 2032-02-10

F2 · derivative.exercise_date: The option vests and becomes exercisable in 48 substantially equal monthly installments with the first installment vesting on March 11, 2022.

SEC source: 0001127602-22-005152 · form4.xml · nonDerivative · entry 1

Spignesi Robert G. Jr. · CIK 0001853904 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,027

F1 · shares: Grant of restricted stock units ("RSUs") that vest in three annual installments with 33.4% vesting on the first anniversary of February 11, 2022 (the "grant date") and 33.3% vesting on each of the second and third anniversaries of the grant date provided that the Reporting Person remains in continuous service on each vesting date.

SEC source: 0001127602-22-005159 · form4.xml · derivative · entry 2

WIRTJES SEAN M · CIK 0001289733 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Class A Common Stock · 80,000 shares

Expires 2032-02-10

F2 · derivative.exercise_date: The option vests and becomes exercisable in 48 substantially equal monthly installments with the first installment vesting on March 11, 2022.

SEC source: 0001127602-22-005159 · form4.xml · nonDerivative · entry 1

WIRTJES SEAN M · CIK 0001289733 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 181,631

F1 · shares: Grant of restricted stock units ("RSUs") that vest in three annual installments with 33.4% vesting on the first anniversary of February 11, 2022 (the "grant date") and 33.3% vesting on each of the second and third anniversaries of the grant date provided that the Reporting Person remains in continuous service on each vesting date.

SEC source: 0001127602-22-005156 · form4.xml · derivative · entry 2

VEZINA VICTORIA · CIK 0001608091 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,500

Underlying: Class A Common Stock · 57,500 shares

Expires 2032-02-10

F2 · derivative.exercise_date: The option vests and becomes exercisable in 48 substantially equal monthly installments with the first installment vesting on March 11, 2022.

SEC source: 0001127602-22-005156 · form4.xml · nonDerivative · entry 1

VEZINA VICTORIA · CIK 0001608091 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,750

F1 · shares: Grant of restricted stock units ("RSUs") that vest in three annual installments with 33.4% vesting on the first anniversary of February 11, 2022 (the "grant date") and 33.3% vesting on each of the second and third anniversaries of the grant date provided that the Reporting Person remains in continuous service on each vesting date.

SEC source: 0001104659-22-009134 · tm224728-1_4aseq1.xml · derivative · entry 1

LOWENSTEIN INESE · CIK 0001900476 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Class A Common Stock · 25,000 shares

Expires 2031-12-16

F1 · derivative.exercise_date: This Option Vests and becomes exercisable, subject to the Reporting Person's continued service to the Issuer's Board, in 36 substantially equal monthly installments with the first installment vesting on January 17, 2022.

SEC source: 0001104659-21-123232 · tm2129262-2_4seq1.xml · derivative · entry 1

KEYS RICHARD A · CIK 0001886207 · CHIEF COMMERCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,000

Underlying: Class A Common Stock · 180,000 shares

Expires 2031-10-01

F1 · derivative.exercise_date: The option vests and becomes exercisable as to 25% of the underlying shares on October 1, 2022 and in 36 substantially equal monthly installments thereafter.

SEC source: 0001104659-21-115207 · tm2127517-1_4seq1.xml · derivative · entry 4

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 12,903 shares

Expires 2028-01-17

F2 · derivative.exercise_date: Immediately exercisable.

F1 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is an executive manager of Quaker Bioventures Capital II, LLC, the general partner of Quaker Bioventures Capital II, L.P, the general partner of Quaker Bioventures II, LP, and may be deemed to beneficially hold the shares but disclaims beneficial ownership thereof, except to the extent of any pecuniary interest therein.

SEC source: 0001104659-21-115207 · tm2127517-1_4seq1.xml · derivative · entry 3

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 12,903 shares

Expires 2027-12-06

F2 · derivative.exercise_date: Immediately exercisable.

F1 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is an executive manager of Quaker Bioventures Capital II, LLC, the general partner of Quaker Bioventures Capital II, L.P, the general partner of Quaker Bioventures II, LP, and may be deemed to beneficially hold the shares but disclaims beneficial ownership thereof, except to the extent of any pecuniary interest therein.

SEC source: 0001104659-21-115207 · tm2127517-1_4seq1.xml · derivative · entry 2

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 82,010 shares

Expires 2027-07-24

F2 · derivative.exercise_date: Immediately exercisable.

F1 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is an executive manager of Quaker Bioventures Capital II, LLC, the general partner of Quaker Bioventures Capital II, L.P, the general partner of Quaker Bioventures II, LP, and may be deemed to beneficially hold the shares but disclaims beneficial ownership thereof, except to the extent of any pecuniary interest therein.

SEC source: 0001104659-21-115207 · tm2127517-1_4seq1.xml · nonDerivative · entry 1

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 1,481,009

F1 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is an executive manager of Quaker Bioventures Capital II, LLC, the general partner of Quaker Bioventures Capital II, L.P, the general partner of Quaker Bioventures II, LP, and may be deemed to beneficially hold the shares but disclaims beneficial ownership thereof, except to the extent of any pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 9

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 129,032

Underlying: Class A Common Stock · 129,032 shares

Expires 2028-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Immediately exercisable.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 8

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Series B1 Preferred Stock · 645,160 shares

Expires 2028-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 7

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 500,000

Underlying: Class A Common Stock · 500,000 shares

Expires 2027-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Immediately exercisable.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 6

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Series A1 Preferred Stock · 2,500,000 shares

Expires 2027-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 5

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 458,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F3 · derivative.exercise_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F3 · derivative.expiration_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 4

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 1,130,904 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F3 · derivative.exercise_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F3 · derivative.expiration_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · derivative · entry 3

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 1,754,801 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F3 · derivative.exercise_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F3 · derivative.expiration_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0000899243-21-029105 · doc4.xml · nonDerivative · entry 2

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Prime Fund, L.P.

Disclosed balance after: 150,000

F2 · ownership.nature: The securities are held directly by Longitude Prime Fund, L.P. ("LPF"). Longitude Prime Partners, LLC ("LPP"), the general partner of LPF, may be deemed to have voting and investment power with respect to the shares held by LPF. Mr. Enright and Ms. Tammenoms Bakker are the managing members of LPP and may be deemed to have voting, investment and dispositive power over the shares held by LPF. LPP and each of Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0000899243-21-029105 · doc4.xml · nonDerivative · entry 1

Longitude Capital Partners II, LLC · CIK 0001647491 · 10% owner

Longitude Venture Partners II, L.P. · CIK 0001527510 · 10% owner

Longitude Prime Partners, LLC · CIK 0001865779 · 10% owner

Longitude Prime Fund, L.P. · CIK 0001865844 · 10% owner

ENRIGHT PATRICK G · CIK 0001253886 · 10% owner

Tammenoms Bakker Juliet · CIK 0001431159 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 3,407,952

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein.

SEC source: 0001104659-21-094109 · tm2122156-20_4seq1.xml · derivative · entry 2

Grewal Gurinder · CIK 0001695567 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Class A Common Stock · 27,777 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series D1 Preferred Stock are convertible at any time, at the holder's election and have no expiration date. Each share of Series D1 Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series D1 Preferred Stock are convertible at any time, at the holder's election and have no expiration date. Each share of Series D1 Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series D1 Preferred Stock are convertible at any time, at the holder's election and have no expiration date. Each share of Series D1 Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series D1 Preferred Stock are convertible at any time, at the holder's election and have no expiration date. Each share of Series D1 Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

SEC source: 0001104659-21-094109 · tm2122156-20_4seq1.xml · nonDerivative · entry 1

Grewal Gurinder · CIK 0001695567 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 294,990

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series D1 Preferred Stock are convertible at any time, at the holder's election and have no expiration date. Each share of Series D1 Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 10

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 12,903

Underlying: Class A Common Stock · 12,903 shares

Expires 2027-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 9

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Series B1 Preferred Stock · 64,516 shares

Expires 2027-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 8

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 12,903

Underlying: Class A Common Stock · 12,903 shares

Expires 2028-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 7

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Series B1 Preferred Stock · 64,516 shares

Expires 2028-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 6

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 82,010

Underlying: Class A Common Stock · 82,010 shares

Expires 2027-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 5

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Series A1 Preferred Stock · 410,051 shares

Expires 2027-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · derivative.exercise_date: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 4

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 164,145 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 3

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 226,180 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · derivative · entry 2

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 924,759 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094111 · tm2122156-21_4seq1.xml · nonDerivative · entry 1

Kollender Richard S · CIK 0001415666 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Quaker Bioventures II, L.P.

Disclosed balance after: 1,373,193

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series A1 Preferred Stock, the Series B1 Preferred Stock and the Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: These shares are held directly by Quaker Bioventures II, L.P. The Reporting Person is a managing director of Quaker Bioventures Capital II, L.P., the parent of Quaker Bioventures II, L.P. and may be deemed to beneficially hold the shares.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 8

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 129,032

Underlying: Class A Common Stock · 129,032 shares

Expires 2028-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 7

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Series B1 Preferred Stock · 645,160 shares

Expires 2028-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · derivative.exercise_date: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 6

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 500,000

Underlying: Class A Common Stock · 500,000 shares

Expires 2027-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 5

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Series A1 Preferred Stock · 2,500,000 shares

Expires 2027-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F3 · price: The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants.

F4 · derivative.exercise_date: Immediately exercisable.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 4

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 458,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 3

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 1,130,904 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · derivative · entry 2

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 0

Underlying: Class A Common Stock · 1,754,801 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.

SEC source: 0001104659-21-094107 · tm2122156-19_4seq1.xml · nonDerivative · entry 1

Hirsch David · CIK 0001619884 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · Held by Longitude Venture Partners II, L.P.

Disclosed balance after: 3,407,952

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering.

F2 · ownership.nature: The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. The Reporting Person is a member of LCP II and may be deemed to share voting and investment power over the shares of the issuer held by LCP II. LCP II and Dr. Hirsch disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein.