Tapewire

Nasdaq · USD

RGNX

REGENXBIO Inc.

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Tapewire entity
2211
SEC CIK
0001590877
Parsed reports
367

Last 12 months

Inside the activity.

2 purchase rows · 5 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202600
Feb 202600
Mar 202601
Apr 202600
May 202601
Jun 202601
Jul 202602
Aug 202620
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 06, 2026 Filed Jan 8, 2026 21:33 UTC
Chan MitchellChief Financial Officer
GrantStock Options (Right to buy) · Derivative 39,650 $0.00 Strike: $14.18 $0.00
Disclosure

SEC source: 0001789335-26-000002 · primarydocument.xml · derivative · entry 2

Chan Mitchell · CIK 0001789335 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,650

Underlying: Common Stock · 39,650 shares

Expires 2036-01-06

F2 · derivative.exercise_date: 25% of the shares subject to this option shall vest after 12 months of continuous service with the Issuer. The balance will vest in equal monthly installments over the 36 months following January 6, 2027 while the optionee provides continuous service to the Issuer.

Read SEC document
January 06, 2026 Filed Jan 8, 2026 21:33 UTC
Chan MitchellChief Financial Officer
GrantCommon Stock 73,749 $0.00 $0.00
Disclosure

SEC source: 0001789335-26-000002 · primarydocument.xml · nonDerivative · entry 1

Chan Mitchell · CIK 0001789335 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 127,717

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 25% of the shares subject to this RSU will vest on each of January 6, 2027, January 6, 2028, January 6, 2029 and January 6, 2030 while the recipient provides continuous service to the Issuer.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 16:31 UTC
Malzahn CraigChief Technology Officer
Tax withholdingCommon Stock 1,238 $14.40 $17,827.20
Disclosure

SEC source: 0002062007-26-000002 · primarydocument.xml · nonDerivative · entry 1

Malzahn Craig · CIK 0002062007 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,347

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 3, 2022, January 3, 2023, and January 2, 2024. The number of shares withheld was determined on January 2, 2026 based on the closing price of the issuer's common stock on December 31, 2025.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:31 UTC
PAKOLA STEVEChief Medical Officer
Tax withholdingCommon Stock 18,247 $14.40 $262,756.80
Disclosure

SEC source: 0001700659-26-000003 · primarydocument.xml · nonDerivative · entry 1

PAKOLA STEVE · CIK 0001700659 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 192,470

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 3, 2022, January 3, 2023, January 2, 2024 and January 2, 2025. The number of shares withheld was determined on January 2, 2026 based on the closing price of the issuer's common stock on December 31, 2025.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:32 UTC
Simpson CurranDirector · Chief Executive Officer
Tax withholdingCommon Stock 18,559 $14.40 $267,249.60
Disclosure

SEC source: 0001346164-26-000002 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 197,603

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 3, 2022, January 3, 2023, January 2, 2024 and January 2, 2025. The number of shares withheld was determined on January 2, 2026 based on the closing price of the issuer's common stock on December 31, 2025.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:31 UTC
Christmas Patrick J.Chief Strategy & Legal Officer
Tax withholdingCommon Stock 9,793 $14.40 $141,019.20
Disclosure

SEC source: 0001521123-26-000002 · primarydocument.xml · nonDerivative · entry 1

Christmas Patrick J. · CIK 0001521123 · Chief Strategy & Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 141,618

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 3, 2022, January 3, 2023 and January 2, 2024. The number of shares withheld was determined on January 2, 2026 based on the closing price of the issuer's common stock on December 31, 2025.

Read SEC document
December 31, 2025 Filed Jul 6, 2026 20:51 UTC
Simpson CurranDirector · Chief Executive Officer
GrantCommon Stock 951 $7.00 $6,652.72
Disclosure

SEC source: 0001346164-26-000006 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 343,418

F1 · security: The reporting person is voluntarily reporting the acquisition of shares of the Issuer's common stock pursuant to the REGENXBIO Inc. Employee Stock Purchase Plan ("ESPP") for the ESPP purchase period of July 1, 2025 through December 31, 2025. This transaction is exempt under Rule 16b-3(c).

F2 · price: In accordance with the ESPP, these shares were purchased based on 85% of the closing price of the Issuer's common stock on July 1, 2025.

Read SEC document
October 09, 2025 Filed Oct 10, 2025 22:38 UTC
Simpson CurranDirector · Chief Executive Officer
SaleCommon Stock 20,811 $12.62 $262,634.82
Disclosure

SEC source: 0001346164-25-000005 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 216,162

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $12.50 to $12.84. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
September 29, 2025 Filed Oct 1, 2025 21:02 UTC
Simpson CurranDirector · Chief Executive Officer
SaleCommon Stock 7,624 $10.03 $76,468.72
Disclosure

SEC source: 0001346164-25-000003 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 236,973

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $10.00 to $10.08. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
September 10, 2025 Filed Sep 12, 2025 20:30 UTC
Simpson CurranDirector · Chief Executive Officer
SaleCommon Stock 7,734 $10.02 $77,494.68
Disclosure

SEC source: 0001562180-25-006194 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 244,597

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $10.00 to $10.07. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
September 01, 2025 Filed Sep 3, 2025 16:49 UTC
Malzahn CraigChief Technology Officer
Tax withholdingCommon Stock 234 $8.93 $2,089.62
Disclosure

SEC source: 0001562180-25-006079 · primarydocument.xml · nonDerivative · entry 1

Malzahn Craig · CIK 0002062007 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,585

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on September 1, 2022. The number of shares withheld was determined based on the closing price of the issuer's common stock on August 29, 2025.

Read SEC document
September 01, 2025 Filed Sep 3, 2025 20:47 UTC
Chan MitchellChief Financial Officer
Tax withholdingCommon Stock 4,901 $8.93 $43,765.93
Disclosure

SEC source: 0001562180-25-006078 · primarydocument.xml · nonDerivative · entry 1

Chan Mitchell · CIK 0001789335 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,968

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on September 16, 2024. The number of shares withheld was determined based on the closing price of the issuer's common stock on August 29, 2025.

Read SEC document
August 01, 2025 Filed Aug 4, 2025 21:17 UTC
Christmas Patrick J.Chief Strategy & Legal Officer
Tax withholdingCommon Stock 4,699 $8.19 $38,484.81
Disclosure

SEC source: 0001562180-25-005618 · primarydocument.xml · nonDerivative · entry 1

Christmas Patrick J. · CIK 0001521123 · Chief Strategy & Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 151,411

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on August 1, 2024. The number of shares withheld was determined based on the closing price of the issuer's common stock on August 1, 2025.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 22:53 UTC
Simpson CurranDirector · Chief Executive Officer
Tax withholdingCommon Stock 4,701 $8.23 $38,689.23
Disclosure

SEC source: 0001562180-25-005334 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 252,331

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on July 1, 2024. The number of shares withheld was determined based on the closing price of the issuer's common stock on July 1, 2025.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:31 UTC
Bennett JeanDirector
GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004347 · primarydocument.xml · derivative · entry 2

Bennett Jean · CIK 0001872219 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:31 UTC
Bennett JeanDirector
GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004347 · primarydocument.xml · nonDerivative · entry 1

Bennett Jean · CIK 0001872219 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:32 UTC GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004350 · primarydocument.xml · derivative · entry 2

MIGAUSKY GEORGE V · CIK 0001134365 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:32 UTC GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004350 · primarydocument.xml · nonDerivative · entry 1

MIGAUSKY GEORGE V · CIK 0001134365 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:33 UTC GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004354 · primarydocument.xml · derivative · entry 2

Zachary Jennifer · CIK 0001737231 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:33 UTC GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004354 · primarydocument.xml · nonDerivative · entry 1

Zachary Jennifer · CIK 0001737231 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,064

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:32 UTC GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004349 · primarydocument.xml · derivative · entry 2

Glucksmann Alexandra · CIK 0001658390 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 31, 2024 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:32 UTC GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004349 · primarydocument.xml · nonDerivative · entry 1

Glucksmann Alexandra · CIK 0001658390 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:37 UTC
Fox Allan M.Director
GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004355 · primarydocument.xml · derivative · entry 6

Fox Allan M. · CIK 0001652936 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F3 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:37 UTC
Fox Allan M.Director
GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004355 · primarydocument.xml · nonDerivative · entry 1

Fox Allan M. · CIK 0001652936 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:32 UTC GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004351 · primarydocument.xml · derivative · entry 2

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:32 UTC GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004351 · primarydocument.xml · nonDerivative · entry 1

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 482,871

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:33 UTC GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004352 · primarydocument.xml · derivative · entry 2

STUMP DAVID C · CIK 0001191235 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:33 UTC GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004352 · primarydocument.xml · nonDerivative · entry 1

STUMP DAVID C · CIK 0001191235 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:31 UTC GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004348 · primarydocument.xml · derivative · entry 2

KARABELAS ARGERIS N · CIK 0001191229 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:31 UTC GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004348 · primarydocument.xml · nonDerivative · entry 1

KARABELAS ARGERIS N · CIK 0001191229 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:33 UTC
Tasse DanielDirector
GrantStock Options (Right to Buy) · Derivative 39,815 $0.00 Strike: $8.85 $0.00
Disclosure

SEC source: 0001562180-25-004353 · primarydocument.xml · derivative · entry 2

Tasse Daniel · CIK 0001502785 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,815

Underlying: Common Stock · 39,815 shares

Expires 2035-05-30

F2 · derivative.exercise_date: The option will vest in 12 equal monthly installments following May 30, 2025 subject to the continuous service of the optionee to the Issuer.

Read SEC document
May 30, 2025 Filed Jun 3, 2025 20:33 UTC
Tasse DanielDirector
GrantCommon Stock 7,768 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-004353 · primarydocument.xml · nonDerivative · entry 1

Tasse Daniel · CIK 0001502785 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,054

F1 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 100% of the shares subject to this RSU will vest on May 1, 2026 subject to the continuous service of the recipient to the Issuer.

Read SEC document
May 12, 2025 Filed May 14, 2025 20:49 UTC Exercise / conversionStock Options (Right to Buy) · Derivative 20,602 $0.00 Strike: $3.76 $0.00
Disclosure

SEC source: 0001562180-25-003822 · primarydocument.xml · derivative · entry 3

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,602 shares

Expires 2025-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan.

F3 · derivative.exercise_date: The previously granted option, representing a right to purchase a total of 275,000 shares, became exercisable as follows: 25% of the shares subject to this option vested on May 19, 2016, and the balance vested in equal monthly installments over the 36 months thereafter.

Read SEC document
May 12, 2025 Filed May 14, 2025 20:49 UTC SaleCommon Stock 20,602 $7.91 $163,046.29
Disclosure

SEC source: 0001562180-25-003822 · primarydocument.xml · nonDerivative · entry 2

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 475,103

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.66 to $8.04. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 12, 2025 Filed May 14, 2025 20:49 UTC Exercise / conversionCommon Stock 20,602 $3.76 $77,463.52
Disclosure

SEC source: 0001562180-25-003822 · primarydocument.xml · nonDerivative · entry 1

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 495,705

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan.

Read SEC document
March 27, 2025 Filed Mar 31, 2025 21:05 UTC Exercise / conversionStock Options (Right to Buy) · Derivative 30,752 $0.00 Strike: $3.76 $0.00
Disclosure

SEC source: 0001562180-25-002804 · primarydocument.xml · derivative · entry 2

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,602

Underlying: Common Stock · 30,752 shares

Expires 2025-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The previously granted option, representing a right to purchase a total of 275,000 shares, became exercisable as follows: 25% of the shares subject to this option vested on May 19, 2016, and the balance vested in equal monthly installments over the 36 months thereafter.

Read SEC document
March 27, 2025 Filed Mar 31, 2025 21:05 UTC Exercise / conversionCommon Stock 30,752 $3.76 $115,627.52
Disclosure

SEC source: 0001562180-25-002804 · primarydocument.xml · nonDerivative · entry 1

Mills Kenneth T. · CIK 0001652824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 475,103

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The previously granted option, representing a right to purchase a total of 275,000 shares, became exercisable as follows: 25% of the shares subject to this option vested on May 19, 2016, and the balance vested in equal monthly installments over the 36 months thereafter.

Read SEC document
February 01, 2025 Filed Apr 4, 2025 21:17 UTC
PAKOLA STEVEChief Medical Officer
Tax withholdingCommon Stock 5,263 $8.07 $42,472.41
Disclosure

SEC source: 0001562180-25-003009 · primarydocument.xml · nonDerivative · entry 1

PAKOLA STEVE · CIK 0001700659 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 210,717

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on August 1, 2024. The number of shares withheld was determined based on the closing price of the issuer's common stock on February 1, 2025

Read SEC document
February 01, 2025 Filed Apr 4, 2025 17:16 UTC
Danos OlivierChief Scientific Officer
Tax withholdingCommon Stock 5,452 $8.07 $43,997.64
Disclosure

SEC source: 0001562180-25-003008 · primarydocument.xml · nonDerivative · entry 1

Danos Olivier · CIK 0001701180 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 226,348

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on August 1, 2024. The number of shares withheld was determined based on the closing price of the issuer's common stock on February 1, 2025.

Read SEC document
February 01, 2025 Filed Apr 4, 2025 21:17 UTC
Christmas Patrick J.Chief Legal Officer
Tax withholdingCommon Stock 4,700 $8.07 $37,929.00
Disclosure

SEC source: 0001562180-25-003010 · primarydocument.xml · nonDerivative · entry 1

Christmas Patrick J. · CIK 0001521123 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 156,110

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on August 1, 2024. The number of shares withheld was determined based on the closing price of the issuer's common stock on February 1, 2025.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
PAKOLA STEVEChief Medical Officer
GrantStock Options (Right to buy) · Derivative 103,698 $0.00 Strike: $7.86 $0.00
Disclosure

SEC source: 0001562180-25-000190 · primarydocument.xml · derivative · entry 3

PAKOLA STEVE · CIK 0001700659 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 103,698

Underlying: Common Stock · 103,698 shares

Expires 2035-01-02

F3 · derivative.exercise_date: 25% of the shares subject to this option shall vest after 12 months of continuous service with the Issuer. The balance will vest in equal monthly installments over the 36 months following January 2, 2026 while the optionee provides continuous service to the Issuer.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
PAKOLA STEVEChief Medical Officer
GrantCommon Stock 64,293 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-000190 · primarydocument.xml · nonDerivative · entry 2

PAKOLA STEVE · CIK 0001700659 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 215,980

F2 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 25% of the shares subject to this RSU will vest on each of January 1, 2026, January 1, 2027, January 1, 2028 and January 1, 2029 while the recipient provides continuous service to the Issuer.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
PAKOLA STEVEChief Medical Officer
Tax withholdingCommon Stock 13,891 $7.73 $107,377.43
Disclosure

SEC source: 0001562180-25-000190 · primarydocument.xml · nonDerivative · entry 1

PAKOLA STEVE · CIK 0001700659 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 151,687

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 4, 2021, January 3, 2022, January 3, 2023 and January 2, 2024. The number of shares withheld was determined on January 2, 2025 based on the closing price of the issuer's common stock on December 31, 2024.

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January 02, 2025 Filed Jan 6, 2025 16:59 UTC
Danos OlivierChief Scientific Officer
GrantStock Options (Right to buy) · Derivative 95,721 $0.00 Strike: $7.86 $0.00
Disclosure

SEC source: 0001562180-25-000189 · primarydocument.xml · derivative · entry 3

Danos Olivier · CIK 0001701180 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 95,721

Underlying: Common Stock · 95,721 shares

Expires 2035-01-02

F3 · derivative.exercise_date: 25% of the shares subject to this option shall vest after 12 months of continuous service with the Issuer. The balance will vest in equal monthly installments over the 36 months following January 2, 2026 while the optionee provides continuous service to the Issuer.

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January 02, 2025 Filed Jan 6, 2025 16:59 UTC
Danos OlivierChief Scientific Officer
GrantCommon Stock 59,347 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-000189 · primarydocument.xml · nonDerivative · entry 2

Danos Olivier · CIK 0001701180 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 231,800

F2 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 25% of the shares subject to this RSU will vest on each of January 1, 2026, January 1, 2027, January 1, 2028 and January 1, 2029 while the recipient provides continuous service to the Issuer.

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January 02, 2025 Filed Jan 6, 2025 16:59 UTC
Danos OlivierChief Scientific Officer
Tax withholdingCommon Stock 12,630 $7.73 $97,629.90
Disclosure

SEC source: 0001562180-25-000189 · primarydocument.xml · nonDerivative · entry 1

Danos Olivier · CIK 0001701180 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 172,453

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 4, 2021, January 3, 2022, January 3, 2023 and January 2, 2024. The number of shares withheld was determined on January 2, 2025 based on the closing price of the issuer's common stock on December 31, 2024.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
Simpson CurranDirector · Chief Executive Officer
GrantStock Options (Right to buy) · Derivative 476,606 $0.00 Strike: $7.86 $0.00
Disclosure

SEC source: 0001562180-25-000188 · primarydocument.xml · derivative · entry 3

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 476,606

Underlying: Common Stock · 476,606 shares

Expires 2035-01-02

F3 · derivative.exercise_date: 25% of the shares subject to this option shall vest after 12 months of continuous service with the Issuer. The balance will vest in equal monthly installments over the 36 months following January 2, 2026 while the optionee provides continuous service to the Issuer.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
Simpson CurranDirector · Chief Executive Officer
GrantCommon Stock 98,912 $0.00 $0.00
Disclosure

SEC source: 0001562180-25-000188 · primarydocument.xml · nonDerivative · entry 2

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 257,032

F2 · shares: Represents shares of common stock underlying a time-based restricted stock unit award (RSU). 25% of the shares subject to this RSU will vest on each of January 1, 2026, January 1, 2027, January 1, 2028 and January 1, 2029 while the recipient provides continuous service to the Issuer.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
Simpson CurranDirector · Chief Executive Officer
Tax withholdingCommon Stock 11,917 $7.73 $92,118.41
Disclosure

SEC source: 0001562180-25-000188 · primarydocument.xml · nonDerivative · entry 1

Simpson Curran · CIK 0001346164 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 158,120

F1 · shares: Represents shares of common stock withheld to pay taxes upon the vesting of restricted stock units originally granted to the reporting person on January 4, 2021, January 3, 2022, January 3, 2023 and January 2, 2024. The number of shares withheld was determined on January 2, 2025 based on the closing price of the issuer's common stock on December 31, 2024.

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January 02, 2025 Filed Jan 6, 2025 21:59 UTC
Christmas Patrick J.Chief Legal Officer
GrantStock Options (Right to buy) · Derivative 223,350 $0.00 Strike: $7.86 $0.00
Disclosure

SEC source: 0001562180-25-000186 · primarydocument.xml · derivative · entry 2

Christmas Patrick J. · CIK 0001521123 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 223,350

Underlying: Common Stock · 223,350 shares

Expires 2035-01-02

F2 · derivative.exercise_date: 25% of the shares subject to this option shall vest after 12 months of continuous service with the Issuer. The balance will vest in equal monthly installments over the 36 months following January 2, 2026 while the optionee provides continuous service to the Issuer.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.