Last 12 months
Inside the activity.
0 purchase rows · 78 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 2 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 35 |
| Mar 2026 | 0 | 13 |
| Apr 2026 | 0 | 9 |
| May 2026 | 0 | 12 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 1 |
| Aug 2026 | 0 | 2 |
| Sep 2026 | 0 | 3 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| August 20, 2018 Filed Aug 21, 2018 20:55 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Tax withholdingCommon Stock | 108 | $374.46 | $40,441.68 |
DisclosureSEC source: 0001237899-18-000014 · edgardoc.xml · nonDerivative · entry 2 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 399,949 Read SEC document |
| August 20, 2018 Filed Aug 21, 2018 20:55 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Exercise / conversionCommon Stock | 210 | $21.25 | $4,462.50 |
DisclosureSEC source: 0001237899-18-000014 · edgardoc.xml · nonDerivative · entry 1 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 400,057 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| August 03, 2018 Filed Dec 14, 2018 21:21 UTC |
YANCOPOULOS GEORGEDirector · President and CSO
|
GiftCommon Stock | 101,187 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 21 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust Disclosed balance after: 487,141 Read SEC document |
| August 03, 2018 Filed Dec 14, 2018 21:21 UTC |
YANCOPOULOS GEORGEDirector · President and CSO
|
GiftCommon Stock | 101,187 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 11 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO 10b5-1 filing: Not disclosed Ownership: Indirect · By 2017 GRAT Disclosed balance after: 75,036 Read SEC document |
| August 02, 2018 Filed Aug 3, 2018 20:03 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $57.11 | $0.00 |
DisclosureSEC source: 0001708138-18-000015 · edgardoc.xml · derivative · entry 3 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 2,000 shares Expires 2022-01-03 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant. Read SEC document |
| August 02, 2018 Filed Aug 3, 2018 20:03 UTC |
GOLDSTEIN JOSEPH LDirector
|
SaleCommon Stock | 2,000 | $380.00 | $760,000.00 |
DisclosureSEC source: 0001708138-18-000015 · edgardoc.xml · nonDerivative · entry 2 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| August 02, 2018 Filed Aug 3, 2018 20:03 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionCommon Stock | 2,000 | $57.11 | $114,220.00 |
DisclosureSEC source: 0001708138-18-000015 · edgardoc.xml · nonDerivative · entry 1 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 14,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 24, 2018 Filed Dec 14, 2018 21:21 UTC |
YANCOPOULOS GEORGEDirector · President and CSO
|
GiftCommon Stock | 299,134 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 20 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust Disclosed balance after: 385,954 Read SEC document |
| July 24, 2018 Filed Dec 14, 2018 21:21 UTC |
YANCOPOULOS GEORGEDirector · President and CSO
|
GiftCommon Stock | 299,134 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 8 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO 10b5-1 filing: Not disclosed Ownership: Indirect · By 2016 GRAT Disclosed balance after: 24,643 Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 300 | $371.29 | $111,387.00 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 10 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 399,847 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F8 · price: Represents volume-weighted average price of sales of 300 shares of Company stock on July 10, 2018 at prices ranging from $371.28 to $371.32. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 100 | $370.17 | $37,017.00 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 9 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 400,147 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 13,194 | $369.41 | $4,873,995.54 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 8 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 400,247 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F7 · price: Represents volume-weighted average price of sales of 13,194 shares of Company stock on July 10, 2018 at prices ranging from $369.00 to $369.87. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 12,211 | $368.61 | $4,501,096.71 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 7 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 413,441 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F6 · price: Represents volume-weighted average price of sales of 12,211 shares of Company stock on July 10, 2018 at prices ranging from $368.01 to $368.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 6,405 | $367.40 | $2,353,197.00 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 6 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 425,652 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F5 · price: Represents volume-weighted average price of sales of 6,405 shares of Company stock on July 10, 2018 at prices ranging from $367.02 to $367.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 24,339 | $366.49 | $8,920,000.11 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 5 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 432,057 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F4 · price: Represents volume-weighted average price of sales of 24,339 shares of Company stock on July 10, 2018 at prices ranging from $366.00 to $366.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 17,221 | $365.56 | $6,295,308.76 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 4 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 456,396 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F3 · price: Represents volume-weighted average price of sales of 17,221 shares of Company stock on July 10, 2018 at prices ranging from $365.05 to $365.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 10, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 900 | $364.75 | $328,275.00 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 3 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 473,617 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · price: Represents volume-weighted average price of sales of 900 shares of Company stock on July 10, 2018 at prices ranging from $364.73 to $364.83. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on July 10, 2018 at each separate price. Read SEC document |
| July 09, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 153,274 | $0.00 Strike: $16.80 | $0.00 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · derivative · entry 15 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 153,274 shares Expires 2018-12-17 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F10 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| July 09, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Tax withholdingCommon Stock | 78,604 | $370.52 | $29,124,354.08 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 2 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 474,517 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 09, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Exercise / conversionCommon Stock | 153,274 | $16.80 | $2,575,003.20 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 1 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 553,121 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 06, 2018 Filed Jul 9, 2018 20:04 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $57.11 | $0.00 |
DisclosureSEC source: 0001708138-18-000011 · edgardoc.xml · derivative · entry 6 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,000 Underlying: Common Stock · 2,000 shares Expires 2022-01-03 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant. Read SEC document |
| July 06, 2018 Filed Jul 9, 2018 20:04 UTC |
GOLDSTEIN JOSEPH LDirector
|
SaleCommon Stock | 2,000 | $370.00 | $740,000.00 |
DisclosureSEC source: 0001708138-18-000011 · edgardoc.xml · nonDerivative · entry 4 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 06, 2018 Filed Jul 9, 2018 20:04 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionCommon Stock | 2,000 | $57.11 | $114,220.00 |
DisclosureSEC source: 0001708138-18-000011 · edgardoc.xml · nonDerivative · entry 3 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 14,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 06, 2018 Filed Jul 11, 2018 20:04 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
GiftCommon Stock | 610 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-18-000013 · edgardoc.xml · nonDerivative · entry 11 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Indirect · by CLAT Disclosed balance after: 147,934 Read SEC document |
| July 05, 2018 Filed Jul 9, 2018 20:04 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $57.11 | $0.00 |
DisclosureSEC source: 0001708138-18-000011 · edgardoc.xml · derivative · entry 5 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,000 Underlying: Common Stock · 2,000 shares Expires 2022-01-03 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant. Read SEC document |
| July 05, 2018 Filed Jul 9, 2018 20:04 UTC |
GOLDSTEIN JOSEPH LDirector
|
SaleCommon Stock | 2,000 | $360.00 | $720,000.00 |
DisclosureSEC source: 0001708138-18-000011 · edgardoc.xml · nonDerivative · entry 2 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| July 05, 2018 Filed Jul 9, 2018 20:04 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionCommon Stock | 2,000 | $57.11 | $114,220.00 |
DisclosureSEC source: 0001708138-18-000011 · edgardoc.xml · nonDerivative · entry 1 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 14,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 200 | $336.87 | $67,374.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 15 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 399,847 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 300 | $335.01 | $100,503.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 14 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 400,047 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F12 · price: Represents volume-weighted average price of sales of 300 shares of Company stock on June 21, 2018 at prices ranging from $335.00 to $335.01. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 500 | $333.15 | $166,575.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 13 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 400,347 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F11 · price: Represents volume-weighted average price of sales of 500 shares of Company stock on June 21, 2018 at prices ranging from $333.01 to $333.28. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 1,300 | $332.80 | $432,640.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 12 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 400,847 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F10 · price: Represents volume-weighted average price of sales of 1,300 shares of Company stock on June 21, 2018 at prices ranging from $332.40 to $332.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 100 | $331.09 | $33,109.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 11 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 402,147 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 3,096 | $330.32 | $1,022,670.72 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 10 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 402,247 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F9 · price: Represents volume-weighted average price of sales of 3,096 shares of Company stock on June 21, 2018 at prices ranging from $330.00 to $330.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 12,854 | $329.51 | $4,235,521.54 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 9 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 405,343 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F8 · price: Represents volume-weighted average price of sales of 12,854 shares of Company stock on June 21, 2018 at prices ranging from $329.00 to $329.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 12,426 | $328.45 | $4,081,319.70 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 8 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 418,197 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F7 · price: Represents volume-weighted average price of sales of 12,426 shares of Company stock on June 21, 2018 at prices ranging from $328.00 to $328.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 19,393 | $327.48 | $6,350,819.64 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 7 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 430,623 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F6 · price: Represents volume-weighted average price of sales of 19,393 shares of Company stock on June 21, 2018 at prices ranging from $327.00 to $327.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 15,594 | $326.57 | $5,092,532.58 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 6 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 450,016 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F5 · price: Represents volume-weighted average price of sales of 15,594 shares of Company stock on June 21, 2018 at prices ranging from $326.00 to $326.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 8,047 | $325.67 | $2,620,666.49 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 5 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 465,610 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F4 · price: Represents volume-weighted average price of sales of 8,047 shares of Company stock on June 21, 2018 at prices ranging from $325.05 to $325.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 500 | $324.18 | $162,090.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 4 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 473,657 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F3 · price: Represents volume-weighted average price of sales of 500 shares of Company stock on June 21, 2018 at prices ranging from $324.16 to $324.23. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 21, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
SaleCommon Stock | 400 | $323.97 | $129,588.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 3 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 474,157 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · price: Represents volume-weighted average price of sales of 400 shares of Company stock on June 21, 2018 at prices ranging from $323.96 to $323.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2018 at each separate price. Read SEC document |
| June 20, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 153,274 | $0.00 Strike: $16.80 | $0.00 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · derivative · entry 21 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 153,274 Underlying: Common Stock · 153,274 shares Expires 2018-12-17 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F14 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| June 20, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Tax withholdingCommon Stock | 78,564 | $333.07 | $26,167,311.48 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 2 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 474,557 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 20, 2018 Filed Jun 22, 2018 20:03 UTC |
VAGELOS P ROYDirector · Chairman of the Board
|
Exercise / conversionCommon Stock | 153,274 | $16.80 | $2,575,003.20 |
DisclosureSEC source: 0001708138-18-000009 · edgardoc.xml · nonDerivative · entry 1 VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 553,121 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 08, 2018 Filed Jun 11, 2018 20:30 UTC |
Sanofi10% owner
|
SaleCommon Stock | 121,601 | $309.31 | $37,611,882.43 |
DisclosureSEC source: 0001140361-18-028055 · form4.xml · nonDerivative · entry 1 Sanofi · CIK 0001121404 · 10% owner 10b5-1 filing: Not disclosed Ownership: Indirect · See note Disclosed balance after: 23,758,936 F1 · kind: Private sale to the Issuer pursuant to the letter agreement entered into with the Issuer on January 7, 2018 and filed on January 9, 2018 by the Reporting Person as Exhibit 99.4 to the Amendment No. 13 to its statement on Schedule 13D. F2 · ownership.nature: Indirectly owned through (a) sanofi-aventis Amerique du Nord, a direct, wholly-owned subsidiary of Sanofi ("SAAN"), and (b) Aventisub LLC ("Aventis"), formerly known as Aventis Pharmaceuticals Inc., an indirect, wholly-owned subsidiary of SAAN. After giving effect to the dispositions reported on this Form 4, the number of shares beneficially owned directly by SAAN and Aventis was 20,959,384 shares and 2,799,552 shares, respectively. Pursuant to the Amended and Restated Investor Agreement, dated as of January 11, 2014, by and among Sanofi, SAAN, sanofi-aventis US LLC, Aventis (collectively, the "Sanofi Parties") and the Issuer, the Sanofi Parties have agreed to vote their respective shares of the Issuer, subject to specified exceptions, in accordance with the recommendation of the Issuer's Board of Directors. Read SEC document |
| May 24, 2018 Filed May 25, 2018 20:03 UTC |
STAHL NEILEVP Research and Development
|
SaleCommon Stock | 11,407 | $295.09 | $3,366,091.63 |
DisclosureSEC source: 0001708138-18-000007 · edgardoc.xml · nonDerivative · entry 3 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 31,973 F1 · kind: Represents volume-weighted average price of sales of 11,407 shares of Company stock on May 24, 2018 at prices ranging from $295.00 to $295.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 24, 2018 at each separate price. Read SEC document |
| May 23, 2018 Filed May 25, 2018 20:03 UTC |
STAHL NEILEVP Research and Development
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 26,736 | $0.00 Strike: $30.63 | $0.00 |
DisclosureSEC source: 0001708138-18-000007 · edgardoc.xml · derivative · entry 7 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 26,736 shares Expires 2020-12-14 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| May 23, 2018 Filed May 25, 2018 20:03 UTC |
STAHL NEILEVP Research and Development
|
Tax withholdingCommon Stock | 15,329 | $293.68 | $4,501,820.72 |
DisclosureSEC source: 0001708138-18-000007 · edgardoc.xml · nonDerivative · entry 2 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 43,380 Read SEC document |
| May 23, 2018 Filed May 25, 2018 20:03 UTC |
STAHL NEILEVP Research and Development
|
Exercise / conversionCommon Stock | 26,736 | $30.63 | $818,923.68 |
DisclosureSEC source: 0001708138-18-000007 · edgardoc.xml · nonDerivative · entry 1 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 58,709 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| May 10, 2018 Filed May 11, 2018 20:02 UTC |
SING GEORGE LDirector
|
SaleCommon Stock | 4,000 | $288.00 | $1,152,000.00 |
DisclosureSEC source: 0001708138-18-000006 · edgardoc.xml · nonDerivative · entry 5 SING GEORGE L · CIK 0001225471 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 114,772 Read SEC document |
| May 10, 2018 Filed May 11, 2018 20:02 UTC |
SING GEORGE LDirector
|
SaleCommon Stock | 3,000 | $287.00 | $861,000.00 |
DisclosureSEC source: 0001708138-18-000006 · edgardoc.xml · nonDerivative · entry 4 SING GEORGE L · CIK 0001225471 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 118,772 Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.