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Nasdaq · USD

REGN

REGENERON PHARMACEUTICALS, INC.

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Tapewire entity
2010
SEC CIK
0000872589
Parsed reports
687

Last 12 months

Inside the activity.

0 purchase rows · 78 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202500
Jan 202601
Feb 2026035
Mar 2026013
Apr 202609
May 2026012
Jun 202600
Jul 202601
Aug 202602
Sep 202603
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
December 12, 2018 Filed Dec 14, 2018 21:12 UTC
LAROSA JOSEPH JSVP General Counsel and Secret
GrantNon-Qualified Stock Option (right to buy) · Derivative 20,000 $0.00 Strike: $381.40 $0.00
Disclosure

SEC source: 0001237899-18-000020 · edgardoc.xml · derivative · entry 1

LAROSA JOSEPH J · CIK 0001238303 · SVP General Counsel and Secret

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2028-12-12

F1 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
December 12, 2018 Filed Dec 14, 2018 21:08 UTC
Landry Robert ESVP Finance & CFO
GrantNon-Qualified Stock Option (right to buy) · Derivative 20,000 $0.00 Strike: $381.40 $0.00
Disclosure

SEC source: 0001237899-18-000019 · edgardoc.xml · derivative · entry 3

Landry Robert E · CIK 0001585160 · SVP Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2028-12-12

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
December 12, 2018 Filed Dec 14, 2018 21:08 UTC
Landry Robert ESVP Finance & CFO
GrantCommon Stock 12,500 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000019 · edgardoc.xml · nonDerivative · entry 1

Landry Robert E · CIK 0001585160 · SVP Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,348

F1 · kind: Award of Restricted Stock under the Amended and Restated 2014 Long-Term Incentive Plan that vests in its entirety on December 12, 2023.

Read SEC document
December 12, 2018 Filed Dec 14, 2018 21:05 UTC
STAHL NEILEVP Research and Development
GrantNon-Qualified Stock Option (right to buy) · Derivative 20,000 $0.00 Strike: $381.40 $0.00
Disclosure

SEC source: 0001708138-18-000029 · edgardoc.xml · derivative · entry 1

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2028-12-12

F1 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
December 12, 2018 Filed Dec 14, 2018 21:06 UTC
McCourt MarionSVP Commercial
GrantNon-Qualified Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $381.40 $0.00
Disclosure

SEC source: 0001708138-18-000030 · edgardoc.xml · derivative · entry 2

McCourt Marion · CIK 0001663758 · SVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-12-12

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
December 12, 2018 Filed Dec 14, 2018 21:06 UTC
McCourt MarionSVP Commercial
GrantCommon Stock 10,000 $0.00 $0.00
Disclosure

SEC source: 0001708138-18-000030 · edgardoc.xml · nonDerivative · entry 1

McCourt Marion · CIK 0001663758 · SVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

F1 · kind: Award of Restricted Stock under the Amended and Restated 2014 Long-Term Incentive Plan that vests in its entirety on December 12, 2023.

Read SEC document
December 12, 2018 Filed Dec 14, 2018 21:03 UTC
Van Plew Daniel PEVP & General Mgr Industrial O
GrantNon-Qualified Stock Option (right to buy) · Derivative 46,250 $0.00 Strike: $381.40 $0.00
Disclosure

SEC source: 0001708138-18-000028 · edgardoc.xml · derivative · entry 1

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr Industrial O

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,250

Underlying: Common Stock · 46,250 shares

Expires 2028-12-12

F1 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
November 16, 2018 Filed Dec 14, 2018 21:49 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 16,161 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000023 · edgardoc.xml · nonDerivative · entry 4

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 314,877

Read SEC document
November 16, 2018 Filed Dec 14, 2018 21:21 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 1,176 $0.00 $0.00
Disclosure

SEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 24

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 483,601

Read SEC document
November 15, 2018 Filed Dec 14, 2018 21:49 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 19,202 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000023 · edgardoc.xml · nonDerivative · entry 3

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 331,038

Read SEC document
November 13, 2018 Filed Dec 14, 2018 21:49 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 37,209 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000023 · edgardoc.xml · nonDerivative · entry 2

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 350,240

Read SEC document
November 01, 2018 Filed Dec 14, 2018 21:21 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 24,643 $0.00 $0.00
Disclosure

SEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 9

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By 2016 GRAT

Disclosed balance after: 0

Read SEC document
October 25, 2018 Filed Dec 14, 2018 21:18 UTC GiftCommon Stock 2,950 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000021 · edgardoc.xml · nonDerivative · entry 5

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Indirect · by 2018 GRAT

Disclosed balance after: 2,950

Read SEC document
October 25, 2018 Filed Dec 14, 2018 21:18 UTC GiftCommon Stock 2,950 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000021 · edgardoc.xml · nonDerivative · entry 4

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 1,397

F2 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's spouse. The reporting person and the reporting person's spouse are trustees of the trust.

Read SEC document
October 04, 2018 Filed Dec 14, 2018 21:49 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 521 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000023 · edgardoc.xml · nonDerivative · entry 6

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 147,413

Read SEC document
September 28, 2018 Filed Oct 1, 2018 20:06 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 709 $0.00 Strike: $273.67 $0.00
Disclosure

SEC source: 0001708138-18-000024 · edgardoc.xml · derivative · entry 6

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,791

Underlying: Common Stock · 709 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
September 28, 2018 Filed Oct 1, 2018 20:06 UTC SaleCommon Stock 709 $410.00 $290,690.00
Disclosure

SEC source: 0001708138-18-000024 · edgardoc.xml · nonDerivative · entry 4

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 28, 2018 Filed Oct 1, 2018 20:06 UTC Exercise / conversionCommon Stock 709 $273.67 $194,032.03
Disclosure

SEC source: 0001708138-18-000024 · edgardoc.xml · nonDerivative · entry 3

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,709

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,000 $0.00 Strike: $273.67 $0.00
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · derivative · entry 10

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,750

Underlying: Common Stock · 2,000 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC SaleCommon Stock 260 $395.42 $102,809.20
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 7

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 260 shares of Company stock on September 27, 2018 at prices ranging from $395.18 to $395.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on September 27, 2018 at each separate price.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC SaleCommon Stock 40 $394.43 $15,777.20
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 6

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 260

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC SaleCommon Stock 300 $393.49 $118,047.00
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 5

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 300 shares of Company stock on September 27, 2018 at prices ranging from $393.41 to $393.55. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on September 27, 2018 at each separate price.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC SaleCommon Stock 410 $392.37 $160,871.70
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 4

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 600

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 410 shares of Company stock on September 27, 2018 at prices ranging from $392.00 to $392.41. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on September 27, 2018 at each separate price.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC SaleCommon Stock 601 $391.38 $235,219.38
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 3

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,010

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 601 shares of Company stock on September 27, 2018 at prices ranging from $391.00 to $391.38. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on September 27, 2018 at each separate price.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC SaleCommon Stock 389 $390.23 $151,799.47
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 2

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,611

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 389 shares of Company stock on September 27, 2018 at prices ranging from $390.00 to $390.54. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on September 27, 2018 at each separate price.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:35 UTC Exercise / conversionCommon Stock 2,000 $273.67 $547,340.00
Disclosure

SEC source: 0001237899-18-000016 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 27, 2018 Filed Oct 1, 2018 20:06 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,000 $0.00 Strike: $273.67 $0.00
Disclosure

SEC source: 0001708138-18-000024 · edgardoc.xml · derivative · entry 5

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

Underlying: Common Stock · 2,000 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
September 27, 2018 Filed Oct 1, 2018 20:06 UTC SaleCommon Stock 2,000 $400.00 $800,000.00
Disclosure

SEC source: 0001708138-18-000024 · edgardoc.xml · nonDerivative · entry 2

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 27, 2018 Filed Oct 1, 2018 20:06 UTC Exercise / conversionCommon Stock 2,000 $273.67 $547,340.00
Disclosure

SEC source: 0001708138-18-000024 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 24, 2018 Filed Sep 25, 2018 20:05 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,000 $0.00 Strike: $273.67 $0.00
Disclosure

SEC source: 0001708138-18-000022 · edgardoc.xml · derivative · entry 6

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,500

Underlying: Common Stock · 1,000 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
September 24, 2018 Filed Sep 25, 2018 20:05 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,000 $0.00 Strike: $273.67 $0.00
Disclosure

SEC source: 0001708138-18-000022 · edgardoc.xml · derivative · entry 5

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

Underlying: Common Stock · 1,000 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
September 24, 2018 Filed Sep 25, 2018 20:05 UTC SaleCommon Stock 1,000 $387.29 $387,290.00
Disclosure

SEC source: 0001708138-18-000022 · edgardoc.xml · nonDerivative · entry 4

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 24, 2018 Filed Sep 25, 2018 20:05 UTC Exercise / conversionCommon Stock 1,000 $273.67 $273,670.00
Disclosure

SEC source: 0001708138-18-000022 · edgardoc.xml · nonDerivative · entry 3

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 24, 2018 Filed Sep 25, 2018 20:05 UTC SaleCommon Stock 1,000 $390.00 $390,000.00
Disclosure

SEC source: 0001708138-18-000022 · edgardoc.xml · nonDerivative · entry 2

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 24, 2018 Filed Sep 25, 2018 20:05 UTC Exercise / conversionCommon Stock 1,000 $273.67 $273,670.00
Disclosure

SEC source: 0001708138-18-000022 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
September 10, 2018 Filed Sep 11, 2018 20:04 UTC
Landry Robert ESVP Finance & CFO
Tax withholdingCommon Stock 2,251 $395.29 $889,797.79
Disclosure

SEC source: 0001708138-18-000021 · edgardoc.xml · nonDerivative · entry 1

Landry Robert E · CIK 0001585160 · SVP Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,848

Read SEC document
September 06, 2018 Filed Sep 10, 2018 21:01 UTC
Sanofi10% owner
SaleCommon Stock 104,552 $406.68 $42,519,249.18
Disclosure

SEC source: 0001140361-18-038175 · form4.xml · nonDerivative · entry 1

Sanofi · CIK 0001121404 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See note

Disclosed balance after: 23,654,384

F1 · kind: Private sale to the Issuer pursuant to the letter agreement entered into with the Issuer on January 7, 2018 and filed on January 9, 2018 by the Reporting Person as Exhibit 99.4 to Amendment No. 13 to Reporting Person's statement on Schedule 13D.

F2 · ownership.nature: Indirectly owned through (a) sanofi-aventis Amerique du Nord, a direct, wholly-owned subsidiary of Sanofi ("SAAN"), and (b) Aventisub LLC ("Aventis"), formerly known as Aventis Pharmaceuticals Inc., an indirect, wholly-owned subsidiary of SAAN. After giving effect to the dispositions reported on this Form 4, the number of shares beneficially owned directly by SAAN and Aventis was 20,854,832 shares and 2,799,552 shares, respectively. Pursuant to the Amended and Restated Investor Agreement, dated as of January 11, 2014, by and among Sanofi, SAAN, sanofi-aventis US LLC, Aventis (collectively, the "Sanofi Parties") and the Issuer, the Sanofi Parties have agreed to vote their respective shares of the Issuer, subject to specified exceptions, in accordance with the recommendation of the Issuer's Board of Directors.

Read SEC document
August 30, 2018 Filed Aug 31, 2018 20:02 UTC Exercise / conversionIncentive Stock Option (right to buy) · Derivative 50 $0.00 Strike: $21.25 $0.00
Disclosure

SEC source: 0001708138-18-000019 · edgardoc.xml · derivative · entry 5

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,175

Underlying: Common Stock · 50 shares

Expires 2019-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 30, 2018 Filed Aug 31, 2018 20:02 UTC Exercise / conversionCommon Stock 50 $21.25 $1,062.50
Disclosure

SEC source: 0001708138-18-000019 · edgardoc.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 30, 2018 Filed Dec 14, 2018 21:18 UTC GiftCommon Stock 50 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000021 · edgardoc.xml · nonDerivative · entry 3

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 4,347

F2 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's spouse. The reporting person and the reporting person's spouse are trustees of the trust.

Read SEC document
August 30, 2018 Filed Dec 14, 2018 21:18 UTC GiftCommon Stock 50 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000021 · edgardoc.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,421

Read SEC document
August 29, 2018 Filed Dec 14, 2018 21:49 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 12,500 $0.00 $0.00
Disclosure

SEC source: 0001237899-18-000023 · edgardoc.xml · nonDerivative · entry 1

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 387,449

Read SEC document
August 22, 2018 Filed Aug 23, 2018 20:01 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,500 $0.00 Strike: $177.82 $0.00
Disclosure

SEC source: 0001708138-18-000017 · edgardoc.xml · derivative · entry 5

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,500 shares

Expires 2023-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

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August 22, 2018 Filed Aug 23, 2018 20:01 UTC SaleCommon Stock 1,500 $380.49 $570,735.00
Disclosure

SEC source: 0001708138-18-000017 · edgardoc.xml · nonDerivative · entry 2

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

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August 22, 2018 Filed Aug 23, 2018 20:01 UTC Exercise / conversionCommon Stock 1,500 $177.82 $266,730.00
Disclosure

SEC source: 0001708138-18-000017 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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August 22, 2018 Filed Dec 14, 2018 21:21 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 3,211 $0.00 $0.00
Disclosure

SEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 23

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 484,777

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August 21, 2018 Filed Dec 14, 2018 21:21 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 847 $0.00 $0.00
Disclosure

SEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 22

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 487,988

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August 21, 2018 Filed Dec 14, 2018 21:21 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 847 $0.00 $0.00
Disclosure

SEC source: 0001104659-18-073103 · a4.xml · nonDerivative · entry 6

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

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August 21, 2018 Filed Jan 4, 2019 21:07 UTC GiftCommon Stock 2,500 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000001 · edgardoc.xml · nonDerivative · entry 2

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,500

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August 20, 2018 Filed Aug 21, 2018 20:55 UTC
VAGELOS P ROYDirector · Chairman of the Board
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 210 $0.00 Strike: $21.25 $0.00
Disclosure

SEC source: 0001237899-18-000014 · edgardoc.xml · derivative · entry 7

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 307,585

Underlying: Common Stock · 210 shares

Expires 2019-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.