Tapewire

Nasdaq · USD

REGN

REGENERON PHARMACEUTICALS, INC.

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Tapewire entity
2010
SEC CIK
0000872589
Parsed reports
687

Last 12 months

Inside the activity.

0 purchase rows · 78 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202500
Jan 202601
Feb 2026035
Mar 2026013
Apr 202609
May 2026012
Jun 202600
Jul 202601
Aug 202602
Sep 202603
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 12, 2019 Filed Nov 13, 2019 21:11 UTC GiftCommon Stock 1,000 $0.00 $0.00
Disclosure

SEC source: 0001708138-19-000012 · edgardoc.xml · nonDerivative · entry 3

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 11,349

Read SEC document
November 12, 2019 Filed Nov 13, 2019 21:11 UTC SaleCommon Stock 4,500 $349.00 $1,570,500.00
Disclosure

SEC source: 0001708138-19-000012 · edgardoc.xml · nonDerivative · entry 2

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 323

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
November 12, 2019 Filed Nov 13, 2019 21:11 UTC Exercise / conversionCommon Stock 4,500 $273.67 $1,231,515.00
Disclosure

SEC source: 0001708138-19-000012 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,823

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
November 08, 2019 Filed Nov 8, 2019 22:02 UTC SaleCommon Stock 1,000 $340.44 $340,440.00
Disclosure

SEC source: 0001237899-19-000018 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,323

F1 · price: Represents volume-weighted average price of sales of 1,000 shares of Company stock on November 8, 2019 at prices ranging from $340.43 to $340.52. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 300 $341.38 $102,414.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 11

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,455

F9 · price: Represents volume-weighted average price of sales of 300 shares of Company stock on November 8, 2019 at prices ranging from $341.09 to $341.72. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 2,064 $340.48 $702,750.72
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 10

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,755

F8 · price: Represents volume-weighted average price of sales of 2,064 shares of Company stock on November 8, 2019 at prices ranging from $340.00 to $340.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 1,100 $339.53 $373,483.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 9

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,819

F7 · price: Represents volume-weighted average price of sales of 1,100 shares of Company stock on November 8, 2019 at prices ranging from $339.05 to $339.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 1,100 $338.54 $372,394.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 8

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,919

F6 · price: Represents volume-weighted average price of sales of 1,100 shares of Company stock on November 8, 2019 at prices ranging from $338.10 to $338.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 1,500 $337.41 $506,115.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 7

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,019

F5 · price: Represents volume-weighted average price of sales of 1,500 shares of Company stock on November 8, 2019 at prices ranging from $337.03 to $337.86. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 500 $336.73 $168,365.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 6

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,519

F4 · price: Represents volume-weighted average price of sales of 500 shares of Company stock on November 8, 2019 at prices ranging from $336.48 to $336.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 400 $335.45 $134,180.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 5

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,019

F3 · price: Represents volume-weighted average price of sales of 400 shares of Company stock on November 8, 2019 at prices ranging from $335.02 to $335.73. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 100 $334.66 $33,466.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 4

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,419

F2 · price: Represents volume-weighted average price of sales of 100 shares of Company stock on November 8, 2019 at prices ranging from $334.48 to $334.68. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 200 $333.32 $66,664.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 3

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,519

F1 · price: Represents volume-weighted average price of sales of 200 shares of Company stock on November 8, 2019 at prices ranging from $333.31 to $333.32. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on November 8, 2019 at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 100 $330.56 $33,056.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 2

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,719

Read SEC document
October 02, 2019 Filed Nov 26, 2019 21:02 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 764 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000024 · edgardoc.xml · nonDerivative · entry 17

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 144,897

Read SEC document
September 10, 2019 Filed Sep 12, 2019 21:00 UTC
Sanofi10% owner
SaleCommon Stock 172,904 $281.15 $48,611,803.99
Disclosure

SEC source: 0001140361-19-016600 · form4.xml · nonDerivative · entry 1

Sanofi · CIK 0001121404 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,550,813

F1 · kind: Private sale to the Issuer pursuant to the letter agreement entered into with the Issuer on January 7, 2018 and filed on January 9, 2018 by the Reporting Person as Exhibit 99.4 to Amendment No. 13 to Reporting Person's statement on Schedule 13D.

F3 · ownership.direct: Pursuant to the Amended and Restated Investor Agreement, dated as of January 11, 2014, by and among the Reporting Person, sanofi-aventis US LLC, Aventis, sanofi-aventis Amerique du Nord (collectively, the "Sanofi Parties") and the Issuer, the Sanofi Parties have agreed to vote their respective shares of the Issuer, subject to specified exceptions, in accordance with the recommendation of the Issuer's Board of Directors.

Read SEC document
August 05, 2019 Filed Dec 13, 2019 21:44 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 75,036 $0.00 $0.00
Disclosure

SEC source: 0000930413-19-003028 · ownership.xml · nonDerivative · entry 11

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 328,352

Read SEC document
August 05, 2019 Filed Dec 13, 2019 21:44 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 75,036 $0.00 $0.00
Disclosure

SEC source: 0000930413-19-003028 · ownership.xml · nonDerivative · entry 6

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · by 2017 GRAT

Disclosed balance after: 0

Read SEC document
July 02, 2019 Filed Nov 26, 2019 21:02 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 669 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000024 · edgardoc.xml · nonDerivative · entry 16

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 145,661

Read SEC document
June 13, 2019 Filed Dec 13, 2019 21:44 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 500,000 $0.00 $0.00
Disclosure

SEC source: 0000930413-19-003028 · ownership.xml · nonDerivative · entry 10

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 253,316

Read SEC document
June 13, 2019 Filed Dec 13, 2019 21:44 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 500,000 $0.00 $0.00
Disclosure

SEC source: 0000930413-19-003028 · ownership.xml · nonDerivative · entry 8

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · by 2019 GRAT

Disclosed balance after: 500,000

Read SEC document
May 24, 2019 Filed May 29, 2019 20:16 UTC
VAGELOS P ROYDirector · Chairman of the Board
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 153,792 $0.00 Strike: $21.25 $0.00
Disclosure

SEC source: 0001237899-19-000016 · edgardoc.xml · derivative · entry 8

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 153,793

Underlying: Common Stock · 153,792 shares

Expires 2019-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
May 24, 2019 Filed May 29, 2019 20:16 UTC
VAGELOS P ROYDirector · Chairman of the Board
Tax withholdingCommon Stock 80,164 $313.64 $25,142,636.96
Disclosure

SEC source: 0001237899-19-000016 · edgardoc.xml · nonDerivative · entry 2

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 388,505

Read SEC document
May 24, 2019 Filed May 29, 2019 20:16 UTC
VAGELOS P ROYDirector · Chairman of the Board
Exercise / conversionCommon Stock 153,792 $21.25 $3,268,080.00
Disclosure

SEC source: 0001237899-19-000016 · edgardoc.xml · nonDerivative · entry 1

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 468,669

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 24, 2019 Filed Nov 12, 2019 21:05 UTC
STAHL NEILEVP Research and Development
GiftCommon Stock 1,300 $0.00 $0.00
Disclosure

SEC source: 0001708138-19-000010 · edgardoc.xml · nonDerivative · entry 1

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,150

Read SEC document
May 15, 2019 Filed May 16, 2019 00:42 UTC SaleCommon Stock 1,000 $305.93 $305,930.00
Disclosure

SEC source: 0001237899-19-000013 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,323

Read SEC document
May 14, 2019 Filed May 15, 2019 20:02 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 3,278 $306.37 $1,004,280.86
Disclosure

SEC source: 0001237899-19-000012 · edgardoc.xml · nonDerivative · entry 4

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,450

F2 · price: Represents volume-weighted average price of sales of 3,278 shares of Company stock on May 14, 2019 at prices ranging from $306.00 to $306.76. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 14, 2019 at each separate price.

Read SEC document
May 14, 2019 Filed May 15, 2019 20:02 UTC
STAHL NEILEVP Research and Development
SaleCommon Stock 6,575 $305.43 $2,008,202.25
Disclosure

SEC source: 0001237899-19-000012 · edgardoc.xml · nonDerivative · entry 3

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,728

F1 · price: Represents volume-weighted average price of sales of 6,575 shares of Company stock on May 14, 2019 at prices ranging from $305.05 to $305.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 14, 2019 at each separate price.

Read SEC document
May 13, 2019 Filed May 15, 2019 20:02 UTC
STAHL NEILEVP Research and Development
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $52.03 $0.00
Disclosure

SEC source: 0001237899-19-000012 · edgardoc.xml · derivative · entry 7

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,079

Underlying: Common Stock · 25,000 shares

Expires 2021-12-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: With respect to 75,000 underlying shares, the option became exercisable on December 31, 2014, based upon the satisfaction by the company of certain performance criteria during the period ended December 31, 2014. With respect to 48,079 underlying shares, the stock option award vested in four equal annual installments, commencing one year after the date of grant.

Read SEC document
May 13, 2019 Filed May 15, 2019 20:02 UTC
STAHL NEILEVP Research and Development
Tax withholdingCommon Stock 15,147 $304.20 $4,607,717.40
Disclosure

SEC source: 0001237899-19-000012 · edgardoc.xml · nonDerivative · entry 2

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,303

Read SEC document
May 13, 2019 Filed May 15, 2019 20:02 UTC
STAHL NEILEVP Research and Development
Exercise / conversionCommon Stock 25,000 $52.03 $1,300,750.00
Disclosure

SEC source: 0001237899-19-000012 · edgardoc.xml · nonDerivative · entry 1

STAHL NEIL · CIK 0001226689 · EVP Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,450

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 18, 2019 Filed Apr 18, 2019 23:04 UTC Exercise / conversionIncentive Stock Option (right to buy) · Derivative 350 $0.00 Strike: $21.25 $0.00
Disclosure

SEC source: 0001237899-19-000011 · edgardoc.xml · derivative · entry 7

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 350 shares

Expires 2019-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
April 18, 2019 Filed Apr 18, 2019 23:04 UTC GiftCommon Stock 350 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000011 · edgardoc.xml · nonDerivative · entry 3

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 1,897

F1 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's spouse. The reporting person and the reporting person's spouse are trustees of the trust.

Read SEC document
April 18, 2019 Filed Apr 18, 2019 23:04 UTC GiftCommon Stock 350 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000011 · edgardoc.xml · nonDerivative · entry 2

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,096

Read SEC document
April 18, 2019 Filed Apr 18, 2019 23:04 UTC Exercise / conversionCommon Stock 350 $21.25 $7,437.50
Disclosure

SEC source: 0001237899-19-000011 · edgardoc.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,446

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2019 Filed May 29, 2019 20:16 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 514 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000016 · edgardoc.xml · nonDerivative · entry 4

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 146,330

Read SEC document
March 21, 2019 Filed Mar 22, 2019 20:03 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 100 $0.00 Strike: $21.25 $0.00
Disclosure

SEC source: 0001708138-19-000008 · edgardoc.xml · derivative · entry 3

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 312,400

Underlying: Common Stock · 100 shares

Expires 2019-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: With respect to 187,500 underlying shares, the option became exercisable on December 31, 2012, based upon the satisfaction by the company of certain performance criteria during the period ended December 31, 2012. With respect to 125,000 underlying shares, the stock option award vested in four equal annual installments, commencing one year after the date of grant.

Read SEC document
March 21, 2019 Filed Mar 22, 2019 20:03 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Exercise / conversionCommon Stock 100 $21.25 $2,125.00
Disclosure

SEC source: 0001708138-19-000008 · edgardoc.xml · nonDerivative · entry 1

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 424,062

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 08, 2019 Filed Mar 13, 2019 00:19 UTC
Sanofi10% owner
SaleCommon Stock 131,115 $412.17 $54,041,315.54
Disclosure

SEC source: 0001140361-19-004808 · form4.xml · nonDerivative · entry 1

Sanofi · CIK 0001121404 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,723,717

F1 · kind: Private sale to the Issuer pursuant to the letter agreement entered into with the Issuer on January 7, 2018 and filed on January 9, 2018 by the Reporting Person as Exhibit 99.4 to Amendment No. 13 to Reporting Person's statement on Schedule 13D.

F3 · ownership.direct: Pursuant to the Amended and Restated Investor Agreement, dated as of January 11, 2014, by and among the Reporting Person, sanofi-aventis US LLC, Aventis, sanofi-aventis Amerique du Nord (collectively, the "Sanofi Parties") and the Issuer, the Sanofi Parties have agreed to vote their respective shares of the Issuer, subject to specified exceptions, in accordance with the recommendation of the Issuer's Board of Directors.

Read SEC document
February 19, 2019 Filed Dec 13, 2019 21:44 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 150,722 $0.00 $0.00
Disclosure

SEC source: 0000930413-19-003028 · ownership.xml · nonDerivative · entry 9

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 753,316

Read SEC document
February 19, 2019 Filed Dec 13, 2019 21:44 UTC
YANCOPOULOS GEORGEDirector · President and CSO
GiftCommon Stock 150,722 $0.00 $0.00
Disclosure

SEC source: 0000930413-19-003028 · ownership.xml · nonDerivative · entry 7

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · by 2018 GRAT

Disclosed balance after: 249,278

Read SEC document
January 18, 2019 Filed Jan 18, 2019 22:01 UTC Exercise / conversionIncentive Stock Option (right to buy) · Derivative 150 $0.00 Strike: $21.25 $0.00
Disclosure

SEC source: 0001237899-19-000008 · edgardoc.xml · derivative · entry 7

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 350

Underlying: Common Stock · 150 shares

Expires 2019-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
January 18, 2019 Filed Jan 18, 2019 22:01 UTC GiftCommon Stock 150 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000008 · edgardoc.xml · nonDerivative · entry 3

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 1,547

F1 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's spouse. The reporting person and the reporting person's spouse are trustees of the trust.

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January 18, 2019 Filed Jan 18, 2019 22:01 UTC GiftCommon Stock 150 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000008 · edgardoc.xml · nonDerivative · entry 2

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,096

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January 18, 2019 Filed Jan 18, 2019 22:01 UTC Exercise / conversionCommon Stock 150 $21.25 $3,187.50
Disclosure

SEC source: 0001237899-19-000008 · edgardoc.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · VP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,246

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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January 10, 2019 Filed Jan 11, 2019 21:06 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,791 $0.00 Strike: $273.67 $0.00
Disclosure

SEC source: 0001237899-19-000007 · edgardoc.xml · derivative · entry 3

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,791 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

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January 10, 2019 Filed Jan 11, 2019 21:06 UTC SaleCommon Stock 1,791 $410.00 $734,310.00
Disclosure

SEC source: 0001237899-19-000007 · edgardoc.xml · nonDerivative · entry 2

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,323

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

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January 10, 2019 Filed Jan 11, 2019 21:06 UTC Exercise / conversionCommon Stock 1,791 $273.67 $490,142.97
Disclosure

SEC source: 0001237899-19-000007 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,114

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

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January 03, 2019 Filed May 29, 2019 20:16 UTC
VAGELOS P ROYDirector · Chairman of the Board
GiftCommon Stock 569 $0.00 $0.00
Disclosure

SEC source: 0001237899-19-000016 · edgardoc.xml · nonDerivative · entry 3

VAGELOS P ROY · CIK 0001013064 · Director · Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 146,844

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January 02, 2019 Filed Jan 4, 2019 21:05 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 3,784 $0.00 Strike: $371.40 $0.00
Disclosure

SEC source: 0001708138-19-000006 · edgardoc.xml · derivative · entry 2

Zoghbi Huda Y · CIK 0001681643 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,784

Underlying: Common Stock · 3,784 shares

Expires 2029-01-02

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.