Last 12 months
Inside the activity.
0 purchase rows · 78 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 2 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 35 |
| Mar 2026 | 0 | 13 |
| Apr 2026 | 0 | 9 |
| May 2026 | 0 | 12 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 1 |
| Aug 2026 | 0 | 2 |
| Sep 2026 | 0 | 3 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| June 21, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
SaleCommon Stock | 8,236 | $534.48 | $4,401,977.28 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · nonDerivative · entry 4 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust for Chldn. Disclosed balance after: 65,640 F2 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F5 · price: Represents volume-weighted average price of sales of 8,236 shares of Company stock on June 21, 2021 at prices ranging from $534.01 to $534.86. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2021 at each separate price. F1 · ownership.nature: As investment trustee of trusts for the benefit of the reporting person's children. Read SEC document |
| June 21, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
SaleCommon Stock | 7,494 | $533.66 | $3,999,248.04 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · nonDerivative · entry 3 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust for Chldn. Disclosed balance after: 73,876 F2 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F4 · price: Represents volume-weighted average price of sales of 7,494 shares of Company stock on June 21, 2021 at prices ranging from $533.14 to $533.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2021 at each separate price. F1 · ownership.nature: As investment trustee of trusts for the benefit of the reporting person's children. Read SEC document |
| June 21, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
SaleCommon Stock | 738 | $532.89 | $393,272.82 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · nonDerivative · entry 2 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust for Chldn. Disclosed balance after: 81,370 F2 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F3 · price: Represents volume-weighted average price of sales of 738 shares of Company stock on June 21, 2021 at prices ranging from $532.56 to $532.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 21, 2021 at each separate price. F1 · ownership.nature: As investment trustee of trusts for the benefit of the reporting person's children. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 2 | $528.37 | $1,056.74 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 7 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,591 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F8 · price: Represents volume-weighted average price of sales of 2 shares of Company stock on June 14, 2021 at prices ranging from $528.16 to $528.57. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 12 | $527.63 | $6,331.56 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 6 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,593 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F7 · price: Represents volume-weighted average price of sales of 12 shares of Company stock on June 14, 2021 at prices ranging from $527.00 to $527.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 10 | $526.48 | $5,264.80 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 5 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,605 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F6 · price: Represents volume-weighted average price of sales of 10 shares of Company stock on June 14, 2021 at prices ranging from $526.04 to $526.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 15 | $525.63 | $7,884.45 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 4 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,615 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F5 · price: Represents volume-weighted average price of sales of 15 shares of Company stock on June 14, 2021 at prices ranging from $525.00 to $525.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 23 | $524.49 | $12,063.27 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 3 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,630 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F4 · price: Represents volume-weighted average price of sales of 23 shares of Company stock on June 14, 2021 at prices ranging from $524.01 to $524.90. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 20 | $523.59 | $10,471.80 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 2 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,653 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F3 · price: Represents volume-weighted average price of sales of 20 shares of Company stock on June 14, 2021 at prices ranging from $523.15 to $523.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:03 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 18 | $522.41 | $9,403.38 |
DisclosureSEC source: 0001708138-21-000024 · edgardoc.xml · nonDerivative · entry 1 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,673 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · price: Represents volume-weighted average price of sales of 18 shares of Company stock on June 14, 2021 at prices ranging from $521.90 to $522.86. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on June 14, 2021 at each separate price. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:02 UTC |
BROWN MICHAEL SDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 1,700 | $0.00 Strike: $371.40 | $0.00 |
DisclosureSEC source: 0001708138-21-000023 · edgardoc.xml · derivative · entry 5 BROWN MICHAEL S · CIK 0001174475 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,084 Underlying: Common Stock · 1,700 shares Expires 2029-01-02 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F3 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that had passed from the date of grant became exercisable, and the remainder became exercisable on the first anniversary of the date of grant. Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:02 UTC |
BROWN MICHAEL SDirector
|
SaleCommon Stock | 1,700 | $525.00 | $892,500.00 |
DisclosureSEC source: 0001708138-21-000023 · edgardoc.xml · nonDerivative · entry 2 BROWN MICHAEL S · CIK 0001174475 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 891 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 14, 2021 Filed Jun 16, 2021 20:02 UTC |
BROWN MICHAEL SDirector
|
Exercise / conversionCommon Stock | 1,700 | $371.40 | $631,380.00 |
DisclosureSEC source: 0001708138-21-000023 · edgardoc.xml · nonDerivative · entry 1 BROWN MICHAEL S · CIK 0001174475 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,591 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 14, 2021 Filed Aug 19, 2021 20:05 UTC |
VAGELOS P ROYDirector
|
GiftCommon Stock | 19,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000062 · edgardoc.xml · nonDerivative · entry 2 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 308,090 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 07, 2021 Filed Jun 8, 2021 20:03 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 1,930 | $0.00 Strike: $374.12 | $0.00 |
DisclosureSEC source: 0001237899-21-000008 · edgardoc.xml · derivative · entry 3 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,431 Underlying: Common Stock · 1,930 shares Expires 2030-01-02 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that had passed from the date of grant became exercisable, and the remainder became exercisable on the first anniversary of the date of grant. Read SEC document |
| June 07, 2021 Filed Jun 8, 2021 20:03 UTC |
GOLDSTEIN JOSEPH LDirector
|
SaleCommon Stock | 1,930 | $525.00 | $1,013,250.00 |
DisclosureSEC source: 0001237899-21-000008 · edgardoc.xml · nonDerivative · entry 2 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,891 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 07, 2021 Filed Jun 8, 2021 20:03 UTC |
GOLDSTEIN JOSEPH LDirector
|
Exercise / conversionCommon Stock | 1,930 | $374.12 | $722,051.60 |
DisclosureSEC source: 0001237899-21-000008 · edgardoc.xml · nonDerivative · entry 1 GOLDSTEIN JOSEPH L · CIK 0001225474 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,821 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 07, 2021 Filed Jun 8, 2021 20:02 UTC |
McCourt MarionEVP Commercial
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 1,000 | $0.00 Strike: $342.93 | $0.00 |
DisclosureSEC source: 0001237899-21-000007 · edgardoc.xml · derivative · entry 4 McCourt Marion · CIK 0001663758 · EVP Commercial 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 16,000 Underlying: Common Stock · 1,000 shares Expires 2028-02-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| June 07, 2021 Filed Jun 8, 2021 20:02 UTC |
McCourt MarionEVP Commercial
|
SaleCommon Stock | 1,000 | $511.65 | $511,650.00 |
DisclosureSEC source: 0001237899-21-000007 · edgardoc.xml · nonDerivative · entry 2 McCourt Marion · CIK 0001663758 · EVP Commercial 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 17,038 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| June 07, 2021 Filed Jun 8, 2021 20:02 UTC |
McCourt MarionEVP Commercial
|
Exercise / conversionCommon Stock | 1,000 | $342.93 | $342,930.00 |
DisclosureSEC source: 0001237899-21-000007 · edgardoc.xml · nonDerivative · entry 1 McCourt Marion · CIK 0001663758 · EVP Commercial 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,038 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| May 27, 2021 Filed Aug 19, 2021 20:05 UTC |
VAGELOS P ROYDirector
|
GiftCommon Stock | 22,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000062 · edgardoc.xml · nonDerivative · entry 1 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 327,090 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| May 19, 2021 Filed Aug 10, 2021 21:05 UTC |
SCHLEIFER LEONARD SDirector · President & CEO
|
GiftCommon Stock | 41,178 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000048 · edgardoc.xml · nonDerivative · entry 6 SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Indirect · by 2019 GRAT Disclosed balance after: 0 Read SEC document |
| May 19, 2021 Filed Aug 10, 2021 21:05 UTC |
SCHLEIFER LEONARD SDirector · President & CEO
|
GiftCommon Stock | 41,178 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000048 · edgardoc.xml · nonDerivative · entry 5 SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust Disclosed balance after: 41,178 F2 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust. Read SEC document |
| May 17, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
SaleCommon Stock | 3,806 | $520.17 | $1,979,767.02 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 8 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 24,280 F3 · price: Represents volume-weighted average price of sales of 3,806 shares of Company stock on May 17, 2021 at prices ranging from $520.02 to $520.61. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 17, 2021 at each separate price. Read SEC document |
| May 17, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
SaleCommon Stock | 10,336 | $519.47 | $5,369,241.92 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 7 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,086 F2 · price: Represents volume-weighted average price of sales of 10,336 shares of Company stock on May 17, 2021 at prices ranging from $519.00 to $519.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 17, 2021 at each separate price. Read SEC document |
| May 17, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
SaleCommon Stock | 3,379 | $518.63 | $1,752,450.77 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 6 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 38,422 F1 · price: Represents volume-weighted average price of sales of 3,379 shares of Company stock on May 17, 2021 at prices ranging from $518.02 to $518.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 17, 2021 at each separate price. Read SEC document |
| May 14, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 40,000 | $0.00 Strike: $179.13 | $0.00 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · derivative · entry 12 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 72,500 Underlying: Common Stock · 40,000 shares Expires 2022-12-14 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_date: The stock option award vested in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| May 14, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 12,500 | $0.00 Strike: $52.03 | $0.00 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · derivative · entry 11 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 12,500 shares Expires 2021-12-16 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: The option became exercisable on December 31, 2014, based upon the satisfaction by the Company of certain performance criteria during the period ended December 31, 2014. Read SEC document |
| May 14, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
Tax withholdingCommon Stock | 7,204 | $516.69 | $3,722,234.76 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 5 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 41,801 Read SEC document |
| May 14, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
Exercise / conversionCommon Stock | 12,500 | $52.03 | $650,375.00 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 4 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 49,005 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| May 14, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
Tax withholdingCommon Stock | 27,775 | $516.69 | $14,351,064.75 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 3 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 36,505 Read SEC document |
| May 14, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
Exercise / conversionCommon Stock | 40,000 | $179.13 | $7,165,200.00 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 2 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 64,280 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| May 07, 2021 Filed May 10, 2021 20:02 UTC |
McCourt MarionEVP Commercial
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 1,000 | $0.00 Strike: $342.93 | $0.00 |
DisclosureSEC source: 0001708138-21-000018 · edgardoc.xml · derivative · entry 4 McCourt Marion · CIK 0001663758 · EVP Commercial 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 17,000 Underlying: Common Stock · 1,000 shares Expires 2028-02-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| May 07, 2021 Filed May 10, 2021 20:02 UTC |
McCourt MarionEVP Commercial
|
SaleCommon Stock | 1,000 | $495.63 | $495,630.00 |
DisclosureSEC source: 0001708138-21-000018 · edgardoc.xml · nonDerivative · entry 2 McCourt Marion · CIK 0001663758 · EVP Commercial 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 17,038 F1 · price: Represents volume-weighted average price of sales of 1,000 shares of Company stock on May 7, 2021 at prices ranging from $495.47 to $495.70. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on May 7, 2021 at each separate price. Read SEC document |
| May 07, 2021 Filed May 10, 2021 20:02 UTC |
McCourt MarionEVP Commercial
|
Exercise / conversionCommon Stock | 1,000 | $342.93 | $342,930.00 |
DisclosureSEC source: 0001708138-21-000018 · edgardoc.xml · nonDerivative · entry 1 McCourt Marion · CIK 0001663758 · EVP Commercial 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,038 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 15, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
GiftClass A Stock · Derivative | 5,383 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · derivative · entry 20 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · by Trust for Son Disclosed balance after: 5,383 Underlying: Common Stock · 5,383 shares Expires not disclosed F15 · derivative.exercise_price: Class A Stock of Regeneron Pharmaceuticals, Inc. ("Regeneron") converts to Common Stock of Regeneron on a one-to-one basis upon certain events or upon election of the shareholder. F16 · derivative.exercise_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F16 · derivative.expiration_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F17 · ownership.nature: These shares of Class A Stock are held in a trust for the benefit of the reporting person's child, of which the reporting person is trustee. Read SEC document |
| April 15, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
GiftClass A Stock · Derivative | 5,383 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · derivative · entry 19 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · by Son Disclosed balance after: 0 Underlying: Common Stock · 5,383 shares Expires not disclosed F15 · derivative.exercise_price: Class A Stock of Regeneron Pharmaceuticals, Inc. ("Regeneron") converts to Common Stock of Regeneron on a one-to-one basis upon certain events or upon election of the shareholder. F16 · derivative.exercise_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F16 · derivative.expiration_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F18 · ownership.nature: These shares of Class A Stock were held in custody for the benefit of the reporting person's child. Read SEC document |
| April 15, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
GiftClass A Stock · Derivative | 14,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · derivative · entry 18 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · by Daughter Disclosed balance after: 0 Underlying: Common Stock · 14,000 shares Expires not disclosed F15 · derivative.exercise_price: Class A Stock of Regeneron Pharmaceuticals, Inc. ("Regeneron") converts to Common Stock of Regeneron on a one-to-one basis upon certain events or upon election of the shareholder. F16 · derivative.exercise_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F16 · derivative.expiration_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F18 · ownership.nature: These shares of Class A Stock were held in custody for the benefit of the reporting person's child. Read SEC document |
| April 15, 2021 Filed Jun 23, 2021 20:02 UTC |
YANCOPOULOS GEORGEDirector · President and Chief Scientific
|
GiftClass A Stock · Derivative | 14,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000026 · edgardoc.xml · derivative · entry 17 YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific 10b5-1 filing: Not disclosed Ownership: Indirect · By Tr. for Daughter Disclosed balance after: 14,000 Underlying: Common Stock · 14,000 shares Expires not disclosed F15 · derivative.exercise_price: Class A Stock of Regeneron Pharmaceuticals, Inc. ("Regeneron") converts to Common Stock of Regeneron on a one-to-one basis upon certain events or upon election of the shareholder. F16 · derivative.exercise_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F16 · derivative.expiration_date: These shares of Class A Stock are presently convertible and such conversion feature does not expire. F17 · ownership.nature: These shares of Class A Stock are held in a trust for the benefit of the reporting person's child, of which the reporting person is trustee. Read SEC document |
| April 01, 2021 Filed Aug 19, 2021 20:05 UTC |
VAGELOS P ROYDirector
|
GiftCommon Stock | 446 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000062 · edgardoc.xml · nonDerivative · entry 4 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · by CLAT Disclosed balance after: 142,350 Read SEC document |
| February 25, 2021 Filed May 18, 2021 20:04 UTC |
STAHL NEILEVP Research and Development
|
GiftCommon Stock | 435 | $0.00 | $0.00 |
DisclosureSEC source: 0001708138-21-000020 · edgardoc.xml · nonDerivative · entry 1 STAHL NEIL · CIK 0001226689 · EVP Research and Development 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 24,280 Read SEC document |
| February 23, 2021 Filed Feb 24, 2021 21:02 UTC |
VAGELOS P ROYDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 248,079 | $0.00 Strike: $52.03 | $0.00 |
DisclosureSEC source: 0001708138-21-000016 · edgardoc.xml · derivative · entry 9 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 248,079 shares Expires 2021-12-16 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| February 23, 2021 Filed Feb 24, 2021 21:02 UTC |
VAGELOS P ROYDirector
|
Exercise / conversionIncentive Stock Option (right to buy) · Derivative | 1,921 | $0.00 Strike: $52.03 | $0.00 |
DisclosureSEC source: 0001708138-21-000016 · edgardoc.xml · derivative · entry 8 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 1,921 shares Expires 2021-12-16 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant. Read SEC document |
| February 23, 2021 Filed Feb 24, 2021 21:02 UTC |
VAGELOS P ROYDirector
|
Tax withholdingCommon Stock | 137,998 | $458.48 | $63,269,323.04 |
DisclosureSEC source: 0001708138-21-000016 · edgardoc.xml · nonDerivative · entry 3 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 349,090 Read SEC document |
| February 23, 2021 Filed Feb 24, 2021 21:02 UTC |
VAGELOS P ROYDirector
|
Exercise / conversionCommon Stock | 248,079 | $52.03 | $12,907,550.37 |
DisclosureSEC source: 0001708138-21-000016 · edgardoc.xml · nonDerivative · entry 2 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 487,088 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| February 23, 2021 Filed Feb 24, 2021 21:02 UTC |
VAGELOS P ROYDirector
|
Exercise / conversionCommon Stock | 1,921 | $52.03 | $99,949.63 |
DisclosureSEC source: 0001708138-21-000016 · edgardoc.xml · nonDerivative · entry 1 VAGELOS P ROY · CIK 0001013064 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 239,009 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| February 01, 2021 Filed Feb 2, 2021 21:06 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 2 | $512.82 | $1,025.64 |
DisclosureSEC source: 0001708138-21-000014 · edgardoc.xml · nonDerivative · entry 7 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,691 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Read SEC document |
| February 01, 2021 Filed Feb 2, 2021 21:06 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 4 | $509.28 | $2,037.12 |
DisclosureSEC source: 0001708138-21-000014 · edgardoc.xml · nonDerivative · entry 6 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,693 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F7 · price: Represents volume-weighted average price of sales of 4 shares of Company stock on February 1, 2021 at prices ranging from $509.14 to $509.67. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2021 at each separate price. Read SEC document |
| February 01, 2021 Filed Feb 2, 2021 21:06 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 16 | $508.52 | $8,136.32 |
DisclosureSEC source: 0001708138-21-000014 · edgardoc.xml · nonDerivative · entry 5 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,697 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F6 · price: Represents volume-weighted average price of sales of 16 shares of Company stock on February 1, 2021 at prices ranging from $508.01 to $508.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2021 at each separate price. Read SEC document |
| February 01, 2021 Filed Feb 2, 2021 21:06 UTC |
RYAN ARTHUR FDirector
|
SaleCommon Stock | 22 | $507.39 | $11,162.58 |
DisclosureSEC source: 0001708138-21-000014 · edgardoc.xml · nonDerivative · entry 4 RYAN ARTHUR F · CIK 0001187443 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,713 F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). F5 · price: Represents volume-weighted average price of sales of 22 shares of Company stock on February 1, 2021 at prices ranging from $507.00 to $507.86. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2021 at each separate price. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.