Tapewire

Nasdaq · USD

REGN

REGENERON PHARMACEUTICALS, INC.

Export transactions ↓
Tapewire entity
2010
SEC CIK
0000872589
Parsed reports
687

Last 12 months

Inside the activity.

0 purchase rows · 78 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202500
Jan 202601
Feb 2026035
Mar 2026013
Apr 202609
May 2026012
Jun 202600
Jul 202601
Aug 202602
Sep 202603
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 10, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 50 $612.31 $30,615.50
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 16

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,957

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 433 $611.00 $264,563.00
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 15

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,007

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 300 $616.27 $184,881.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 13

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,931

F10 · price: Represents volume-weighted average price of sales of 300 shares of Company stock on August 10, 2021 at prices ranging from $616.01 to $616.51. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 280 $615.22 $172,261.60
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 12

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,231

F9 · price: Represents volume-weighted average price of sales of 280 shares of Company stock on August 10, 2021 at prices ranging from $615.00 to $615.45. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 1,120 $614.33 $688,049.60
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 11

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,511

F8 · price: Represents volume-weighted average price of sales of 1,120 shares of Company stock on August 10, 2021 at prices ranging from $614.08 to $614.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 1,600 $613.34 $981,344.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 10

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,631

F7 · price: Represents volume-weighted average price of sales of 1,600 shares of Company stock on August 10, 2021 at prices ranging from $613.07 to $613.78. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 900 $612.45 $551,205.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 9

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,231

F6 · price: Represents volume-weighted average price of sales of 900 shares of Company stock on August 10, 2021 at prices ranging from $612.03 to $612.85. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 400 $611.57 $244,628.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 8

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,131

F5 · price: Represents volume-weighted average price of sales of 400 shares of Company stock on August 10, 2021 at prices ranging from $611.22 to $611.85. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 100 $610.81 $61,081.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 7

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,531

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 200 $609.25 $121,850.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 6

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,631

F4 · price: Represents volume-weighted average price of sales of 200 shares of Company stock on August 10, 2021 at prices ranging from $609.21 to $609.29. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 697 $608.50 $424,124.50
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 5

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,831

F3 · price: Represents volume-weighted average price of sales of 697 shares of Company stock on August 10, 2021 at prices ranging from $608.17 to $608.61. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 762 $607.21 $462,694.02
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 4

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,528

F2 · price: Represents volume-weighted average price of sales of 762 shares of Company stock on August 10, 2021 at prices ranging from $607.00 to $607.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
SaleCommon Stock 244 $606.50 $147,986.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 3

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,290

F1 · price: Represents volume-weighted average price of sales of 244 shares of Company stock on August 10, 2021 at prices ranging from $606.32 to $606.62. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 1,000 $613.01 $613,010.00
Disclosure

SEC source: 0001237899-21-000011 · edgardoc.xml · nonDerivative · entry 5

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,063

F1 · price: Represents volume-weighted average price of sales of 1,000 shares of Company stock on August 10, 2021 at prices ranging from $613.00 to $613.05. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 1,000 $614.00 $614,000.00
Disclosure

SEC source: 0001237899-21-000011 · edgardoc.xml · nonDerivative · entry 4

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,063

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 600 $615.00 $369,000.00
Disclosure

SEC source: 0001237899-21-000011 · edgardoc.xml · nonDerivative · entry 3

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,063

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 3,000 $0.00 Strike: $381.92 $0.00
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · derivative · entry 23

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,565

Underlying: Common Stock · 3,000 shares

Expires 2026-12-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F12 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
Tax withholdingCommon Stock 2,463 $617.68 $1,521,345.84
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 14

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,440

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
Exercise / conversionCommon Stock 3,000 $381.92 $1,145,760.00
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 13

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,903

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 36 $623.54 $22,447.44
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 12

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,903

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F9 · price: Represents volume-weighted average price of sales of 36 shares of Company stock on August 9, 2021 at prices ranging from $623.40 to $623.69. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 54 $621.19 $33,544.26
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 11

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,939

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · price: Represents volume-weighted average price of sales of 54 shares of Company stock on August 9, 2021 at prices ranging from $621.02 to $621.40. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 36 $619.70 $22,309.20
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 10

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,993

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · price: Represents volume-weighted average price of sales of 36 shares of Company stock on August 9, 2021 at prices ranging from $619.48 to $619.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 58 $618.44 $35,869.52
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 9

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,029

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 58 shares of Company stock on August 9, 2021 at prices ranging from $618.14 to $618.57. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 36 $617.83 $22,241.88
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 8

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,087

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 36 shares of Company stock on August 9, 2021 at prices ranging from $617.73 to $617.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 40 $615.42 $24,616.80
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 7

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,123

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 40 shares of Company stock on August 9, 2021 at prices ranging from $615.35 to $615.51. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 66 $614.70 $40,570.20
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 6

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,163

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 66 shares of Company stock on August 9, 2021 at prices ranging from $614.34 to $614.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 1 $613.79 $613.79
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 5

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,229

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 36 $612.97 $22,066.92
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 4

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,230

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 36 shares of Company stock on August 9, 2021 at prices ranging from $612.97 to $612.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 9, 2021 at each separate price.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 1 $610.85 $610.85
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 3

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,266

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $270.43 $0.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · derivative · entry 15

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2023-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
Tax withholdingCommon Stock 18,397 $617.68 $11,363,458.96
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 2

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,534

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:54 UTC
Van Plew Daniel PEVP & General Mgr, Industrial
Exercise / conversionCommon Stock 25,000 $270.43 $6,760,750.00
Disclosure

SEC source: 0001708138-21-000049 · edgardoc.xml · nonDerivative · entry 1

Van Plew Daniel P · CIK 0001411984 · EVP & General Mgr, Industrial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,931

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 09, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 1,687 $612.38 $1,033,085.06
Disclosure

SEC source: 0001237899-21-000012 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 7,662

Read SEC document
August 09, 2021 Filed Aug 19, 2021 20:05 UTC GiftCommon Stock 17,000 $0.00 $0.00
Disclosure

SEC source: 0001708138-21-000062 · edgardoc.xml · nonDerivative · entry 3

VAGELOS P ROY · CIK 0001013064 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 291,090

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,000 $0.00 Strike: $381.92 $0.00
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · derivative · entry 22

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,565

Underlying: Common Stock · 2,000 shares

Expires 2026-12-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F12 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
Tax withholdingCommon Stock 1,636 $607.51 $993,886.36
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 2

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,267

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
Exercise / conversionCommon Stock 2,000 $381.92 $763,840.00
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 1

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,903

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:05 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 160,000 $0.00 Strike: $52.03 $0.00
Disclosure

SEC source: 0001708138-21-000048 · edgardoc.xml · derivative · entry 10

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 160,000 shares

Expires 2021-12-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · derivative.exercise_date: With respect to 240,000 underlying shares (of which 0 remain outstanding), the option became exercisable on December 31, 2014, based upon the satisfaction by the company of certain performance criteria during the period ended December 31, 2014. With respect to 160,000 underlying shares (of which 0 remain outstanding), the stock option award vested in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:05 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 240,000 $0.00 Strike: $52.03 $0.00
Disclosure

SEC source: 0001708138-21-000048 · edgardoc.xml · derivative · entry 9

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160,000

Underlying: Common Stock · 240,000 shares

Expires 2021-12-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · derivative.exercise_date: With respect to 240,000 underlying shares (of which 0 remain outstanding), the option became exercisable on December 31, 2014, based upon the satisfaction by the company of certain performance criteria during the period ended December 31, 2014. With respect to 160,000 underlying shares (of which 0 remain outstanding), the stock option award vested in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:05 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Tax withholdingCommon Stock 91,430 $607.51 $55,544,639.30
Disclosure

SEC source: 0001708138-21-000048 · edgardoc.xml · nonDerivative · entry 4

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 504,746

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:05 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Exercise / conversionCommon Stock 160,000 $52.03 $8,324,800.00
Disclosure

SEC source: 0001708138-21-000048 · edgardoc.xml · nonDerivative · entry 3

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 596,176

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:05 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Tax withholdingCommon Stock 137,145 $607.51 $83,316,958.95
Disclosure

SEC source: 0001708138-21-000048 · edgardoc.xml · nonDerivative · entry 2

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 436,176

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:05 UTC
SCHLEIFER LEONARD SDirector · President & CEO
Exercise / conversionCommon Stock 240,000 $52.03 $12,487,200.00
Disclosure

SEC source: 0001708138-21-000048 · edgardoc.xml · nonDerivative · entry 1

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 573,321

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 350 $612.42 $214,347.00
Disclosure

SEC source: 0001237899-21-000011 · edgardoc.xml · nonDerivative · entry 6

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust for Son

Disclosed balance after: 3,350

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 1,000 $611.23 $611,230.00
Disclosure

SEC source: 0001237899-21-000011 · edgardoc.xml · nonDerivative · entry 2

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,663

Read SEC document
August 06, 2021 Filed Aug 10, 2021 21:00 UTC SaleCommon Stock 3,000 $611.43 $1,834,290.00
Disclosure

SEC source: 0001237899-21-000011 · edgardoc.xml · nonDerivative · entry 1

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,663

Read SEC document
August 05, 2021 Filed Aug 6, 2021 20:03 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
SaleCommon Stock 50,000 $600.06 $30,003,000.00
Disclosure

SEC source: 0001708138-21-000044 · edgardoc.xml · nonDerivative · entry 1

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 937,483

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 50,000 shares of Company stock on August 5, 2021 at prices ranging from $600.00 to $600.79. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 5, 2021 at each separate price.

Read SEC document
August 05, 2021 Filed Aug 6, 2021 20:02 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,559 $0.00 Strike: $391.92 $0.00
Disclosure

SEC source: 0001708138-21-000043 · edgardoc.xml · derivative · entry 3

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,118

Underlying: Common Stock · 2,559 shares

Expires 2026-09-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
August 05, 2021 Filed Aug 6, 2021 20:02 UTC SaleCommon Stock 2,559 $600.00 $1,535,400.00
Disclosure

SEC source: 0001708138-21-000043 · edgardoc.xml · nonDerivative · entry 2

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 891

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 05, 2021 Filed Aug 6, 2021 20:02 UTC Exercise / conversionCommon Stock 2,559 $391.92 $1,002,923.28
Disclosure

SEC source: 0001708138-21-000043 · edgardoc.xml · nonDerivative · entry 1

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,450

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.