Tapewire

Nasdaq · USD

REGN

REGENERON PHARMACEUTICALS, INC.

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Tapewire entity
2010
SEC CIK
0000872589
Parsed reports
687

Last 12 months

Inside the activity.

0 purchase rows · 78 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202500
Jan 202601
Feb 2026035
Mar 2026013
Apr 202609
May 2026012
Jun 202600
Jul 202601
Aug 202602
Sep 202603
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 20, 2021 Filed Aug 24, 2021 20:06 UTC
LAROSA JOSEPH JEVP General Counsel and Secret
Tax withholdingCommon Stock 6,575 $664.85 $4,371,388.75
Disclosure

SEC source: 0001237899-21-000018 · edgardoc.xml · nonDerivative · entry 2

LAROSA JOSEPH J · CIK 0001238303 · EVP General Counsel and Secret

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,607

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 20, 2021 Filed Aug 24, 2021 20:06 UTC
LAROSA JOSEPH JEVP General Counsel and Secret
Exercise / conversionCommon Stock 10,000 $179.13 $1,791,300.00
Disclosure

SEC source: 0001237899-21-000018 · edgardoc.xml · nonDerivative · entry 1

LAROSA JOSEPH J · CIK 0001238303 · EVP General Counsel and Secret

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,182

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 20, 2021 Filed Aug 24, 2021 20:04 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 13,500 $0.00 Strike: $179.13 $0.00
Disclosure

SEC source: 0001237899-21-000017 · edgardoc.xml · derivative · entry 15

Fenimore Christopher R. · CIK 0001697422 · SVP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 13,500 shares

Expires 2022-12-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
August 20, 2021 Filed Aug 24, 2021 20:04 UTC Exercise / conversionCommon Stock 13,500 $179.13 $2,418,255.00
Disclosure

SEC source: 0001237899-21-000017 · edgardoc.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · SVP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,520

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 20, 2021 Filed Aug 25, 2021 20:06 UTC Amendment Tax withholdingCommon Stock 8,719 $664.85 $5,796,827.15
Disclosure

SEC source: 0001104659-21-109328 · tm2125915-1_4aseq1.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · SVP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,020

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · balance_after: The amount of securities shown following the reported transaction gives effect to the other transactions reported by the Reporting Person in the Original Form 4.

Read SEC document
August 19, 2021 Filed Aug 20, 2021 20:02 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 10,000 $660.03 $6,600,300.00
Disclosure

SEC source: 0001708138-21-000064 · edgardoc.xml · nonDerivative · entry 2

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 21,178

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 10,000 shares of Company stock on August 19, 2021 at prices ranging from $660.00 to $660.13. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 19, 2021 at each separate price.

F4 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 18, 2021 Filed Aug 19, 2021 20:05 UTC SaleCommon Stock 10,039 $650.04 $6,525,751.56
Disclosure

SEC source: 0001708138-21-000062 · edgardoc.xml · nonDerivative · entry 6

VAGELOS P ROY · CIK 0001013064 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Spouse as Trustee

Disclosed balance after: 37,747

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 10,039 shares of Company stock on August 18, 2021 at prices ranging from $650.00 to $650.31. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 18, 2021 at each separate price.

Read SEC document
August 18, 2021 Filed Aug 19, 2021 20:04 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 5,100 $0.00 Strike: $345.47 $0.00
Disclosure

SEC source: 0001708138-21-000061 · edgardoc.xml · derivative · entry 6

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,039

Underlying: Common Stock · 5,100 shares

Expires 2027-01-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
August 18, 2021 Filed Aug 19, 2021 20:04 UTC SaleCommon Stock 5,100 $650.00 $3,315,000.00
Disclosure

SEC source: 0001708138-21-000061 · edgardoc.xml · nonDerivative · entry 4

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 902

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 18, 2021 Filed Aug 19, 2021 20:04 UTC Exercise / conversionCommon Stock 5,100 $345.47 $1,761,897.00
Disclosure

SEC source: 0001708138-21-000061 · edgardoc.xml · nonDerivative · entry 3

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,002

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 18, 2021 Filed Aug 20, 2021 20:02 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 200,000 $650.03 $130,006,000.00
Disclosure

SEC source: 0001708138-21-000064 · edgardoc.xml · nonDerivative · entry 1

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 304,746

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 200,000 shares of Company stock on August 18, 2021 at prices ranging from $650.00 to $650.63. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 18, 2021 at each separate price.

Read SEC document
August 17, 2021 Filed Aug 19, 2021 20:04 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 900 $0.00 Strike: $345.47 $0.00
Disclosure

SEC source: 0001708138-21-000061 · edgardoc.xml · derivative · entry 5

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,139

Underlying: Common Stock · 900 shares

Expires 2027-01-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
August 17, 2021 Filed Aug 19, 2021 20:04 UTC SaleCommon Stock 900 $650.00 $585,000.00
Disclosure

SEC source: 0001708138-21-000061 · edgardoc.xml · nonDerivative · entry 2

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 902

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 17, 2021 Filed Aug 19, 2021 20:04 UTC Exercise / conversionCommon Stock 900 $345.47 $310,923.00
Disclosure

SEC source: 0001708138-21-000061 · edgardoc.xml · nonDerivative · entry 1

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,802

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 303 $629.54 $190,750.62
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 15

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 31,178

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F17 · price: Represents volume-weighted average price of sales of 303 shares of Company stock on August 16, 2021 at prices ranging from $629.18 to $629.86. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 675 $628.41 $424,176.75
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 14

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 31,481

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F16 · price: Represents volume-weighted average price of sales of 675 shares of Company stock on August 16, 2021 at prices ranging from $628.03 to $628.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 1,111 $627.51 $697,163.61
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 13

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 32,156

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F15 · price: Represents volume-weighted average price of sales of 1,111 shares of Company stock on August 16, 2021 at prices ranging from $627.02 to $627.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 295 $626.15 $184,714.25
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 12

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 33,267

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F14 · price: Represents volume-weighted average price of sales of 295 shares of Company stock on August 16, 2021 at prices ranging from $626.04 to $626.63. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 1,355 $625.19 $847,132.45
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 11

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 33,562

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F13 · price: Represents volume-weighted average price of sales of 1,355 shares of Company stock on August 16, 2021 at prices ranging from $625.01 to $625.88. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 1,862 $624.42 $1,162,670.04
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 10

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 34,917

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F12 · price: Represents volume-weighted average price of sales of 1,862 shares of Company stock on August 16, 2021 at prices ranging from $624.00 to $624.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 2,393 $623.66 $1,492,418.38
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 9

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 36,779

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F11 · price: Represents volume-weighted average price of sales of 2,393 shares of Company stock on August 16, 2021 at prices ranging from $623.08 to $623.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 924 $622.44 $575,134.56
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 8

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 39,172

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F10 · price: Represents volume-weighted average price of sales of 924 shares of Company stock on August 16, 2021 at prices ranging from $622.00 to $622.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 287 $621.76 $178,445.12
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 7

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 40,096

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F9 · price: Represents volume-weighted average price of sales of 287 shares of Company stock on August 16, 2021 at prices ranging from $621.25 to $621.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 96 $620.36 $59,554.56
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 6

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 40,383

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · price: Represents volume-weighted average price of sales of 96 shares of Company stock on August 16, 2021 at prices ranging from $620.35 to $620.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 34 $619.83 $21,074.22
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 5

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 40,479

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · price: Represents volume-weighted average price of sales of 34 shares of Company stock on August 16, 2021 at prices ranging from $619.67 to $619.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 90 $618.82 $55,693.80
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 4

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 40,513

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 90 shares of Company stock on August 16, 2021 at prices ranging from $618.13 to $618.89. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 258 $617.79 $159,389.82
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 3

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 40,603

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 258 shares of Company stock on August 16, 2021 at prices ranging from $617.56 to $617.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 146 $616.70 $90,038.20
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 2

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 40,861

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 146 shares of Company stock on August 16, 2021 at prices ranging from $616.66 to $616.73. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:42 UTC
SCHLEIFER LEONARD SDirector · President & CEO
SaleCommon Stock 171 $615.54 $105,257.34
Disclosure

SEC source: 0001708138-21-000058 · edgardoc.xml · nonDerivative · entry 1

SCHLEIFER LEONARD S · CIK 0001218629 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 41,007

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 171 shares of Company stock on August 16, 2021 at prices ranging from $615.35 to $615.79. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

F3 · ownership.nature: These shares are held in a trust for the benefit of the reporting person's family members. The reporting person's spouse is a trustee of the trust.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:17 UTC SaleCommon Stock 1,000 $627.50 $627,500.00
Disclosure

SEC source: 0001237899-21-000016 · edgardoc.xml · nonDerivative · entry 2

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust for Son

Disclosed balance after: 2,050

F1 · price: Represents volume-weighted average price of sales of 1,000 shares of Company stock on August 16, 2021 at prices ranging from $627.37 to $627.62. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:17 UTC SaleCommon Stock 705 $630.00 $444,150.00
Disclosure

SEC source: 0001237899-21-000016 · edgardoc.xml · nonDerivative · entry 1

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,858

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:16 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,219 $0.00 Strike: $376.69 $0.00
Disclosure

SEC source: 0001708138-21-000056 · edgardoc.xml · derivative · entry 3

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,219

Underlying: Common Stock · 1,219 shares

Expires 2027-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

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August 16, 2021 Filed Aug 17, 2021 20:16 UTC SaleCommon Stock 1,219 $630.00 $767,970.00
Disclosure

SEC source: 0001708138-21-000056 · edgardoc.xml · nonDerivative · entry 2

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 891

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:16 UTC Exercise / conversionCommon Stock 1,219 $376.69 $459,185.11
Disclosure

SEC source: 0001708138-21-000056 · edgardoc.xml · nonDerivative · entry 1

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,110

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 16, 2021 Filed Aug 17, 2021 20:13 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
SaleCommon Stock 2,302 $626.10 $1,441,282.20
Disclosure

SEC source: 0001708138-21-000055 · edgardoc.xml · nonDerivative · entry 3

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 887,483

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 2,302 shares of Company stock on August 16, 2021 at prices ranging from $626.00 to $626.14. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

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August 16, 2021 Filed Aug 17, 2021 20:13 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
SaleCommon Stock 46,925 $625.25 $29,339,856.25
Disclosure

SEC source: 0001708138-21-000055 · edgardoc.xml · nonDerivative · entry 2

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 889,785

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 46,925 shares of Company stock on August 16, 2021 at prices ranging from $625.00 to $625.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 16, 2021 at each separate price.

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August 16, 2021 Filed Nov 17, 2021 21:04 UTC
MURPHY ANDREW JEVP Research
GiftCommon Stock 1,645 $0.00 $0.00
Disclosure

SEC source: 0001708138-21-000086 · edgardoc.xml · nonDerivative · entry 1

MURPHY ANDREW J · CIK 0001796226 · EVP Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,705

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August 13, 2021 Filed Aug 13, 2021 21:19 UTC SaleCommon Stock 500 $620.00 $310,000.00
Disclosure

SEC source: 0001237899-21-000014 · edgardoc.xml · nonDerivative · entry 4

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,563

Read SEC document
August 13, 2021 Filed Aug 16, 2021 20:04 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,000 $0.00 Strike: $345.47 $0.00
Disclosure

SEC source: 0001708138-21-000052 · edgardoc.xml · derivative · entry 3

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,039

Underlying: Common Stock · 2,000 shares

Expires 2027-01-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

Read SEC document
August 13, 2021 Filed Aug 16, 2021 20:04 UTC SaleCommon Stock 2,000 $625.00 $1,250,000.00
Disclosure

SEC source: 0001708138-21-000052 · edgardoc.xml · nonDerivative · entry 2

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 902

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 13, 2021 Filed Aug 16, 2021 20:04 UTC Exercise / conversionCommon Stock 2,000 $345.47 $690,940.00
Disclosure

SEC source: 0001708138-21-000052 · edgardoc.xml · nonDerivative · entry 1

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,902

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 13, 2021 Filed Aug 17, 2021 20:13 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
SaleCommon Stock 773 $625.00 $483,125.00
Disclosure

SEC source: 0001708138-21-000055 · edgardoc.xml · nonDerivative · entry 1

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 936,710

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 12, 2021 Filed Aug 13, 2021 21:19 UTC SaleCommon Stock 1,000 $611.00 $611,000.00
Disclosure

SEC source: 0001237899-21-000014 · edgardoc.xml · nonDerivative · entry 3

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,063

Read SEC document
August 11, 2021 Filed Aug 13, 2021 21:19 UTC SaleCommon Stock 300 $620.00 $186,000.00
Disclosure

SEC source: 0001237899-21-000014 · edgardoc.xml · nonDerivative · entry 5

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust for Son

Disclosed balance after: 3,050

Read SEC document
August 11, 2021 Filed Aug 13, 2021 21:19 UTC SaleCommon Stock 1,000 $621.00 $621,000.00
Disclosure

SEC source: 0001237899-21-000014 · edgardoc.xml · nonDerivative · entry 2

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,063

Read SEC document
August 11, 2021 Filed Aug 13, 2021 21:19 UTC SaleCommon Stock 1,000 $620.00 $620,000.00
Disclosure

SEC source: 0001237899-21-000014 · edgardoc.xml · nonDerivative · entry 1

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,063

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 7 $619.19 $4,334.33
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 20

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,903

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F11 · price: Represents volume-weighted average price of sales of 7 shares of Company stock on August 10, 2021 at prices ranging from $619.16 to $619.24. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

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August 10, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 45 $618.89 $27,850.05
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 19

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,910

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F10 · price: Represents volume-weighted average price of sales of 45 shares of Company stock on August 10, 2021 at prices ranging from $618.13 to $618.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on August 10, 2021 at each separate price.

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 1 $615.73 $615.73
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 18

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,955

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
August 10, 2021 Filed Aug 10, 2021 21:55 UTC
Landry Robert EEVP Finance CFO
SaleCommon Stock 1 $614.09 $614.09
Disclosure

SEC source: 0001708138-21-000050 · edgardoc.xml · nonDerivative · entry 17

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,956

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.