Tapewire

Nasdaq · USD

REGN

REGENERON PHARMACEUTICALS, INC.

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Tapewire entity
2010
SEC CIK
0000872589
Parsed reports
687

Last 12 months

Inside the activity.

0 purchase rows · 78 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202500
Jan 202601
Feb 2026035
Mar 2026013
Apr 202609
May 2026012
Jun 202600
Jul 202601
Aug 202602
Sep 202603
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 5 $610.17 $3,050.85
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 11

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,487

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · price: Represents volume-weighted average price of sales of 5 shares of Company stock on February 1, 2022 at prices ranging from $610.02 to $610.59. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 36 $609.50 $21,942.00
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 10

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,492

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · price: Represents volume-weighted average price of sales of 36 shares of Company stock on February 1, 2022 at prices ranging from $609.00 to $609.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 1 $608.74 $608.74
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 9

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,528

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 3 $607.56 $1,822.68
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 8

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,529

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 3 shares of Company stock on February 1, 2022 at prices ranging from $607.46 to $607.77. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 20 $606.74 $12,134.80
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 7

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,532

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 20 shares of Company stock on February 1, 2022 at prices ranging from $606.07 to $606.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 7 $605.50 $4,238.50
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 6

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,552

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 7 shares of Company stock on February 1, 2022 at prices ranging from $605.19 to $605.63. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 1 $604.26 $604.26
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 5

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,559

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 6 $603.61 $3,621.66
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 4

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,560

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 6 shares of Company stock on February 1, 2022 at prices ranging from $603.06 to $603.89. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 13 $602.35 $7,830.55
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 3

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,566

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 13 shares of Company stock on February 1, 2022 at prices ranging from $602.09 to $602.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2022 at each separate price.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 1 $601.79 $601.79
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 2

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,579

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:16 UTC SaleCommon Stock 2 $600.89 $1,201.78
Disclosure

SEC source: 0001708138-22-000012 · edgardoc.xml · nonDerivative · entry 1

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,580

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:14 UTC
McCourt MarionEVP Commercial
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,000 $0.00 Strike: $342.93 $0.00
Disclosure

SEC source: 0001708138-22-000010 · edgardoc.xml · derivative · entry 4

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common Stock · 1,000 shares

Expires 2028-02-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:14 UTC
McCourt MarionEVP Commercial
SaleCommon Stock 1,000 $607.46 $607,460.00
Disclosure

SEC source: 0001708138-22-000010 · edgardoc.xml · nonDerivative · entry 2

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,644

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
February 01, 2022 Filed Feb 2, 2022 21:14 UTC
McCourt MarionEVP Commercial
Exercise / conversionCommon Stock 1,000 $342.93 $342,930.00
Disclosure

SEC source: 0001708138-22-000010 · edgardoc.xml · nonDerivative · entry 1

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,644

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
January 04, 2022 Filed Mar 15, 2022 20:01 UTC GiftCommon Stock 338 $0.00 $0.00
Disclosure

SEC source: 0001883850-22-000020 · edgardoc.xml · nonDerivative · entry 3

VAGELOS P ROY · CIK 0001013064 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 141,292

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:18 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001708138-22-000005 · edgardoc.xml · derivative · entry 4

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F3 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:18 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001708138-22-000005 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,082

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:24 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001883850-22-000009 · edgardoc.xml · derivative · entry 2

Zoghbi Huda Y · CIK 0001681643 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:24 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001883850-22-000009 · edgardoc.xml · nonDerivative · entry 1

Zoghbi Huda Y · CIK 0001681643 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,082

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:44 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001883850-22-000012 · edgardoc.xml · derivative · entry 2

POON CHRISTINE A · CIK 0001189014 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:44 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001883850-22-000012 · edgardoc.xml · nonDerivative · entry 1

POON CHRISTINE A · CIK 0001189014 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,872

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:25 UTC
McCourt MarionEVP Commercial
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 1,000 $0.00 Strike: $342.93 $0.00
Disclosure

SEC source: 0001883850-22-000010 · edgardoc.xml · derivative · entry 4

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 1,000 shares

Expires 2028-02-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:25 UTC
McCourt MarionEVP Commercial
SaleCommon Stock 1,000 $625.00 $625,000.00
Disclosure

SEC source: 0001883850-22-000010 · edgardoc.xml · nonDerivative · entry 2

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,644

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:25 UTC
McCourt MarionEVP Commercial
Exercise / conversionCommon Stock 1,000 $342.93 $342,930.00
Disclosure

SEC source: 0001883850-22-000010 · edgardoc.xml · nonDerivative · entry 1

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,644

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:23 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001883850-22-000008 · edgardoc.xml · derivative · entry 2

Tessier-Lavigne Marc · CIK 0001437435 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:23 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001883850-22-000008 · edgardoc.xml · nonDerivative · entry 1

Tessier-Lavigne Marc · CIK 0001437435 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,269

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:23 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001883850-22-000007 · edgardoc.xml · derivative · entry 2

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:23 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001883850-22-000007 · edgardoc.xml · nonDerivative · entry 1

COLES N ANTHONY · CIK 0001197018 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,093

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · derivative · entry 10

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F10 · derivative.exercise_date: On the date of the Company's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 9

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,582

F9 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Company's common stock.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 2 $628.87 $1,257.74
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 8

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,391

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · price: Represents volume-weighted average price of sales of 2 shares of Company stock on January 3, 2022 at prices ranging from $628.76 to $628.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 6 $627.22 $3,763.32
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 7

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,393

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · price: Represents volume-weighted average price of sales of 6 shares of Company stock on January 3, 2022 at prices ranging from $627.00 to $627.31. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 5 $626.48 $3,132.40
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 6

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,399

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 5 shares of Company stock on January 3, 2022 at prices ranging from $626.29 to $626.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 45 $625.56 $28,150.20
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 5

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,404

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 45 shares of Company stock on January 3, 2022 at prices ranging from $625.00 to $625.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 14 $624.30 $8,740.20
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 4

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,449

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 14 shares of Company stock on January 3, 2022 at prices ranging from $624.04 to $624.69. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 19 $623.62 $11,848.78
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 3

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,463

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 19 shares of Company stock on January 3, 2022 at prices ranging from $623.41 to $623.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 8 $622.52 $4,980.16
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 2

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,482

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 8 shares of Company stock on January 3, 2022 at prices ranging from $622.32 to $622.88. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2022 at each separate price.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC SaleCommon Stock 1 $621.98 $621.98
Disclosure

SEC source: 0001708138-22-000008 · edgardoc.xml · nonDerivative · entry 1

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,490

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001883850-22-000006 · edgardoc.xml · derivative · entry 2

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

Read SEC document
January 03, 2022 Filed Jan 5, 2022 21:22 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001883850-22-000006 · edgardoc.xml · nonDerivative · entry 1

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,082

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

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January 03, 2022 Filed Jan 5, 2022 21:21 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001708138-22-000007 · edgardoc.xml · derivative · entry 5

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

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January 03, 2022 Filed Jan 5, 2022 21:21 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001708138-22-000007 · edgardoc.xml · nonDerivative · entry 1

SING GEORGE L · CIK 0001225471 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,049

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

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January 03, 2022 Filed Jan 5, 2022 21:19 UTC GrantNon-Qualified Stock Option (right to buy) · Derivative 2,707 $0.00 Strike: $625.60 $0.00
Disclosure

SEC source: 0001708138-22-000006 · edgardoc.xml · derivative · entry 2

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,707

Underlying: Common Stock · 2,707 shares

Expires 2032-01-03

F2 · derivative.exercise_date: On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

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January 03, 2022 Filed Jan 5, 2022 21:19 UTC GrantCommon Stock 191 $0.00 $0.00
Disclosure

SEC source: 0001708138-22-000006 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,082

F1 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock.

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December 22, 2021 Filed Dec 23, 2021 21:29 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 203,204 $0.00 Strike: $270.43 $0.00
Disclosure

SEC source: 0001883850-21-000034 · edgardoc.xml · derivative · entry 8

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 203,204 shares

Expires 2023-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

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December 22, 2021 Filed Dec 23, 2021 21:29 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 239,063 $0.00 Strike: $179.13 $0.00
Disclosure

SEC source: 0001883850-21-000034 · edgardoc.xml · derivative · entry 7

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 239,063 shares

Expires 2022-12-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

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December 22, 2021 Filed Dec 23, 2021 21:29 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
Tax withholdingCommon Stock 150,182 $610.04 $91,617,027.28
Disclosure

SEC source: 0001883850-21-000034 · edgardoc.xml · nonDerivative · entry 4

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,019,653

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December 22, 2021 Filed Dec 23, 2021 21:29 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
Exercise / conversionCommon Stock 203,204 $270.43 $54,952,457.72
Disclosure

SEC source: 0001883850-21-000034 · edgardoc.xml · nonDerivative · entry 3

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,169,835

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 22, 2021 Filed Dec 23, 2021 21:29 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
Tax withholdingCommon Stock 159,915 $610.04 $97,554,546.60
Disclosure

SEC source: 0001883850-21-000034 · edgardoc.xml · nonDerivative · entry 2

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 966,631

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December 22, 2021 Filed Dec 23, 2021 21:29 UTC
YANCOPOULOS GEORGEDirector · President and Chief Scientific
Exercise / conversionCommon Stock 239,063 $179.13 $42,823,355.19
Disclosure

SEC source: 0001883850-21-000034 · edgardoc.xml · nonDerivative · entry 1

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,126,546

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.