REGN

SEC source: 0001883850-23-000046 · edgardoc.xml · nonDerivative · entry 1

GOLDSTEIN JOSEPH L · CIK 0001225474 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,860

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000045 · edgardoc.xml · derivative · entry 5

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,070

Underlying: Common Stock · 3,071 shares

Expires 2026-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000045 · edgardoc.xml · nonDerivative · entry 3

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 6,162

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000045 · edgardoc.xml · nonDerivative · entry 2

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,247

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000045 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,318

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000044 · edgardoc.xml · nonDerivative · entry 1

YANCOPOULOS GEORGE · CIK 0001226690 · Director · President and Chief Scientific

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust for Chldn.

Disclosed balance after: 200,504

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 13,189 shares of Company stock on February 6, 2023 at prices ranging from $800.00 to $800.48. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 6, 2023 at each separate price.

F3 · ownership.nature: As investment trustee of trusts for the benefit of the reporting person's children.

SEC source: 0001883850-23-000037 · edgardoc.xml · derivative · entry 9

Fenimore Christopher R. · CIK 0001697422 · SVP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,000 shares

Expires 2023-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000037 · edgardoc.xml · nonDerivative · entry 2

Fenimore Christopher R. · CIK 0001697422 · SVP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,295

SEC source: 0001883850-23-000037 · edgardoc.xml · nonDerivative · entry 1

Fenimore Christopher R. · CIK 0001697422 · SVP Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,581

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001883850-23-000036 · edgardoc.xml · derivative · entry 3

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,720

Underlying: Common Stock · 1,021 shares

Expires 2028-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000036 · edgardoc.xml · nonDerivative · entry 2

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,247

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000036 · edgardoc.xml · nonDerivative · entry 1

Bassler Bonnie L · CIK 0001683607 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,268

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000035 · edgardoc.xml · derivative · entry 19

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 800

Underlying: Common Stock · 3,000 shares

Expires 2026-12-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F9 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000035 · edgardoc.xml · nonDerivative · entry 3

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,857

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000035 · edgardoc.xml · nonDerivative · entry 2

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,105

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000035 · edgardoc.xml · nonDerivative · entry 1

Landry Robert E · CIK 0001585160 · EVP Finance CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,105

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 11

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,247

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F12 · price: Represents volume-weighted average price of sales of 2 shares of Company stock on February 1, 2023 at prices ranging from $762.15 to $762.19. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 10

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,249

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F11 · price: Represents volume-weighted average price of sales of 3 shares of Company stock on February 1, 2023 at prices ranging from $761.49 to $761.62. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 9

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,252

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F10 · price: Represents volume-weighted average price of sales of 4 shares of Company stock on February 1, 2023 at prices ranging from $760.09 to $760.73. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 8

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,256

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F9 · price: Represents volume-weighted average price of sales of 4 shares of Company stock on February 1, 2023 at prices ranging from $759.30 to $759.83. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 7

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,260

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · price: Represents volume-weighted average price of sales of 7 shares of Company stock on February 1, 2023 at prices ranging from $758.29 to $758.88. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 6

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,267

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · price: Represents volume-weighted average price of sales of 2 shares of Company stock on February 1, 2023 at prices ranging from $757.02 to $757.56. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 5

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,269

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 24 shares of Company stock on February 1, 2023 at prices ranging from $756.18 to $756.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 4

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,293

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 17 shares of Company stock on February 1, 2023 at prices ranging from $755.11 to $755.88. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 3

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,310

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 17 shares of Company stock on February 1, 2023 at prices ranging from $754.08 to $754.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 2

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,327

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 18 shares of Company stock on February 1, 2023 at prices ranging from $753.05 to $753.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000031 · edgardoc.xml · nonDerivative · entry 1

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,345

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 2 shares of Company stock on February 1, 2023 at prices ranging from $752.02 to $752.19. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on February 1, 2023 at each separate price.

SEC source: 0001883850-23-000029 · edgardoc.xml · derivative · entry 4

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,650

Underlying: Common Stock · 1,100 shares

Expires 2029-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · derivative.exercise_date: The stock option award vests in four equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000029 · edgardoc.xml · nonDerivative · entry 2

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,079

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000029 · edgardoc.xml · nonDerivative · entry 1

McCourt Marion · CIK 0001663758 · EVP Commercial

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,179

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000027 · edgardoc.xml · derivative · entry 5

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,141

Underlying: Common Stock · 1 shares

Expires 2026-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000027 · edgardoc.xml · nonDerivative · entry 2

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,247

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000027 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,248

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000025 · edgardoc.xml · derivative · entry 5

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,142

Underlying: Common Stock · 3,070 shares

Expires 2026-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · derivative.exercise_date: The stock option becomes exercisable in three equal annual installments, commencing one year after the date of grant.

SEC source: 0001883850-23-000025 · edgardoc.xml · nonDerivative · entry 2

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,247

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F2 · price: Represents volume-weighted average price of sales of 3,070 shares of Company stock on January 6, 2023 at prices ranging from $747.00 to $747.50. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 6, 2023 at each separate price.

SEC source: 0001883850-23-000025 · edgardoc.xml · nonDerivative · entry 1

BROWN MICHAEL S · CIK 0001174475 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,317

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000050 · edgardoc.xml · nonDerivative · entry 3

VAGELOS P ROY · CIK 0001013064 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by CLAT

Disclosed balance after: 125,752

SEC source: 0001883850-23-000023 · edgardoc.xml · derivative · entry 14

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,929

Underlying: Common Stock · 1,929 shares

Expires 2033-01-03

F14 · derivative.exercise_date: On the date of the Company's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 13

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,347

F13 · kind: Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Company's common stock.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 12

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,182

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F12 · price: Represents volume-weighted average price of sales of 2 shares of Company stock on January 3, 2023 at prices ranging from $732.00 to $732.35. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 11

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,184

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F11 · price: Represents volume-weighted average price of sales of 12 shares of Company stock on January 3, 2023 at prices ranging from $731.03 to $731.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 10

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,196

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F10 · price: Represents volume-weighted average price of sales of 4 shares of Company stock on January 3, 2023 at prices ranging from $730.17 to $730.71. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 9

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,200

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 8

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,201

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F9 · price: Represents volume-weighted average price of sales of 11 shares of Company stock on January 3, 2023 at prices ranging from $728.02 to $728.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 7

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,212

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F8 · price: Represents volume-weighted average price of sales of 13 shares of Company stock on January 3, 2023 at prices ranging from $727.06 to $727.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 6

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,225

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F7 · price: Represents volume-weighted average price of sales of 10 shares of Company stock on January 3, 2023 at prices ranging from $726.00 to $726.90. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 5

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,235

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F6 · price: Represents volume-weighted average price of sales of 9 shares of Company stock on January 3, 2023 at prices ranging from $725.00 to $725.86. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 4

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,244

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F5 · price: Represents volume-weighted average price of sales of 9 shares of Company stock on January 3, 2023 at prices ranging from $724.05 to $724.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 3

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,253

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F4 · price: Represents volume-weighted average price of sales of 10 shares of Company stock on January 3, 2023 at prices ranging from $723.25 to $723.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.

SEC source: 0001883850-23-000023 · edgardoc.xml · nonDerivative · entry 2

RYAN ARTHUR F · CIK 0001187443 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,263

F1 · kind: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).

F3 · price: Represents volume-weighted average price of sales of 5 shares of Company stock on January 3, 2023 at prices ranging from $722.01 to $722.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on January 3, 2023 at each separate price.