QTRX

SEC source: 0001562180-22-006033 · primarydocument.xml · nonDerivative · entry 1

MEISTER PAUL M · CIK 0001033876 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 204,654

F1 · price: This transaction was executed in multiple trades at prices ranging from $7.58 to $8.57. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 2,668 restricted stock units.

SEC source: 0001562180-22-006032 · primarydocument.xml · nonDerivative · entry 1

Madaus Martin D · CIK 0001310268 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 254,633

F1 · price: This transaction was executed in multiple trades at prices ranging from $8.195 to $8.61. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Held by a trust.

SEC source: 0001562180-22-006034 · primarydocument.xml · nonDerivative · entry 1

WALT DAVID R · CIK 0001205236 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,431,312

F1 · price: This transaction was executed in multiple trades at prices ranging from $8.58 to $8.66. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 2,668 restricted stock units.

SEC source: 0001562180-22-005860 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,671

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $15.58 to $15.6412. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 20,232 restricted stock units.

SEC source: 0001562180-22-005861 · primarydocument.xml · nonDerivative · entry 2

DOYLE MICHAEL A · CIK 0001284533 · CFO and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,614

F3 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 115 RSUs.

F4 · price: This transaction was executed in multiple trades at prices ranging from $15.58 to $15.6412. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F5 · balance_after: Includes 17,588 restricted stock units.

SEC source: 0001562180-22-005862 · primarydocument.xml · nonDerivative · entry 1

Toloue Masoud · CIK 0001867276 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,823

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 1,408 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $15.58 to $15.6412. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 67,548 restricted stock units.

SEC source: 0001562180-22-005861 · primarydocument.xml · nonDerivative · entry 1

DOYLE MICHAEL A · CIK 0001284533 · CFO and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,651

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 1,382 RSUs.

F2 · balance_after: Includes 17,703 restricted stock units.

SEC source: 0001562180-22-005562 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,072

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $16.18 to $17.10. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 21,008 restricted stock units.

SEC source: 0001562180-22-005564 · primarydocument.xml · nonDerivative · entry 1

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 910,249

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $16.18 to $17.10. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 58,604 restricted stock units and 39,815 shares of common stock subject to performance based vesting.

SEC source: 0001562180-22-005563 · primarydocument.xml · nonDerivative · entry 1

Toloue Masoud · CIK 0001867276 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,269

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 1,408 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $16.18 to $17.10. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 68,956 restricted stock units.

SEC source: 0001562180-22-005561 · primarydocument.xml · nonDerivative · entry 1

MEISTER PAUL M · CIK 0001033876 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,307

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the second quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on July 1, 2022.

F3 · balance_after: Includes 2,668 restricted stock units.

SEC source: 0001562180-22-005560 · primarydocument.xml · nonDerivative · entry 1

Hlavinka Sarah E. · CIK 0001433554 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,110

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the second quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on July 1, 2022.

F3 · balance_after: Includes 4,182 restricted stock units.

SEC source: 0001562180-22-005559 · primarydocument.xml · nonDerivative · entry 1

CRANDELL KEITH · CIK 0001219039 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,642

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the second quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on July 1, 2022.

F3 · balance_after: Includes 2,668 restricted stock units.

SEC source: 0001562180-22-005558 · primarydocument.xml · nonDerivative · entry 1

Flynn Karen · CIK 0001553599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,391

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the second quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on July 1, 2022.

F3 · balance_after: Includes 13,227 restricted stock units.

SEC source: 0001562180-22-005099 · primarydocument.xml · nonDerivative · entry 1

Toloue Masoud · CIK 0001867276 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,701

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 16,901 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $14.86 to $15.84. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 70,364 restricted stock units.

SEC source: 0001562180-22-005091 · primarydocument.xml · derivative · entry 2

Flynn Karen · CIK 0001553599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,841

Underlying: Common Stock · 19,841 shares

Expires 2032-06-06

F3 · derivative.exercise_date: The option vests as to one-third of the shares on June 6, 2023, and the remaining two-thirds of the shares vest monthly thereafter over two years in 24 successive equal installments.

SEC source: 0001562180-22-005091 · primarydocument.xml · nonDerivative · entry 1

Flynn Karen · CIK 0001553599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,227

F1 · shares: Represents shares of stock issuable on vesting of restricted stock units. The restricted stock units vest as to one-third of shares on each of June 6, 2023, June 6, 2024 and June 6, 2025.

F2 · balance_after: Includes 13,227 restricted stock units.

SEC source: 0001562180-22-004769 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,459

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $17.35 to $17.53. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 21,784 restricted stock units.

SEC source: 0001562180-22-004770 · primarydocument.xml · nonDerivative · entry 1

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 911,209

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $17.35 to 17.53. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 60,672 restricted stock units and 39,815 shares of common stock that are subject to performance based vesting.

SEC source: 0001562180-22-003672 · primarydocument.xml · nonDerivative · entry 2

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,837

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F4 · price: This transaction was executed in multiple trades at prices ranging from $22.67 to $22.705. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 22,560 restricted stock units.

SEC source: 0001562180-22-003672 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,921

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $21.67 to $22.65. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 22,560 restricted stock units.

SEC source: 0001562180-22-003674 · primarydocument.xml · nonDerivative · entry 2

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 911,921

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F4 · price: This transaction was executed in multiple trades at prices ranging from $22.67 to $22.705. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 62,740 restricted stock units and 39,815 shares of common stock that are subject to performance based vesting.

SEC source: 0001562180-22-003674 · primarydocument.xml · nonDerivative · entry 1

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 912,048

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $21.67 to $22.65. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 62,740 restricted stock units and 39,815 shares of common stock that are subject to performance based vesting.

SEC source: 0001562180-22-003552 · primarydocument.xml · derivative · entry 2

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,718

Underlying: Common Stock · 59,718 shares

Expires 2032-04-25

F3 · derivative.exercise_date: The option vests as to 25% of the shares on April 25, 2023, and the remaining 75% vests in 36 equal monthly installments at the end of each month beginning on April 30, 2023.

SEC source: 0001562180-22-003552 · primarydocument.xml · nonDerivative · entry 1

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 912,570

F1 · shares: Represents shares of stock issuable upon vesting of restricted stock units (RSUs). The RSUs vest as to 25% of the shares on April 25, 2023, with the remaining 75% vesting in 36 equal monthly installments at the end of each month thereafter beginning on April 30, 2023.

F2 · balance_after: Includes 64,808 restricted stock units and 39,815 shares of common stock that are subject to performance based vesting.

SEC source: 0001562180-22-003551 · primarydocument.xml · derivative · entry 2

Toloue Masoud · CIK 0001867276 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,312

Underlying: Common Stock · 85,312 shares

Expires 2032-04-25

F3 · derivative.exercise_date: The option vests as to 25% of the shares on April 25, 2023, and the remaining 75% vests in 36 equal monthly installments at the end of each month beginning on April 30, 2023.

SEC source: 0001562180-22-003551 · primarydocument.xml · nonDerivative · entry 1

Toloue Masoud · CIK 0001867276 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,265

F1 · shares: Represents shares of stock issuable upon vesting of restricted stock units (RSUs). The RSUs vest as to 25% of the shares on April 25, 2023, with the remaining 75% vesting in 36 equal monthly installments at the end of each month thereafter beginning on April 30, 2023.

F2 · balance_after: Includes 87,265 restricted stock units.

SEC source: 0001562180-22-003365 · primarydocument.xml · derivative · entry 2

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,086

Underlying: Common Stock · 21,086 shares

Expires 2032-04-07

F3 · derivative.exercise_date: The option vests as to 25% of the shares on April 7, 2023, and the remaining 75% vests in 36 equal monthly installments at the end of each month beginning on July 31, 2023.

SEC source: 0001562180-22-003365 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,266

F1 · shares: Represents shares of stock issuable on vesting of restricted stock units. The restricted stock units vest as to 25% of the shares on April 7, 2023, and the remaining 75% vest in 36 equal monthly installments at the end of each month beginning on July 31, 2023.

F2 · balance_after: Includes 14,299 restricted stock units.

SEC source: 0001562180-22-003366 · primarydocument.xml · derivative · entry 2

DOYLE MICHAEL A · CIK 0001284533 · CFO and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,629

Underlying: Common Stock · 31,629 shares

Expires 2032-04-07

F3 · derivative.exercise_date: The option vests as to 25% of the shares on April 7, 2023, and the remaining 75% vests in 36 equal monthly installments at the end of each month beginning on July 31, 2023.

SEC source: 0001562180-22-003366 · primarydocument.xml · nonDerivative · entry 1

DOYLE MICHAEL A · CIK 0001284533 · CFO and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,085

F1 · shares: Represents shares of stock issuable on vesting of restricted stock units. The restricted stock units vest as to 25% of the shares on April 7, 2023, and the remaining 75% vest in 36 equal monthly installments at the end of each month beginning on July 31, 2023.

F2 · balance_after: Includes 19,085 restricted stock units.

SEC source: 0001562180-22-003532 · primarydocument.xml · derivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,086

Underlying: Common Stock · 21,086 shares

Expires 2032-04-07

F1 · derivative.exercise_date: The option vests as to 25% of the shares on April 7, 2023, and the remaining 75% vests in 36 equal monthly installments at the end of each month beginning on July 31, 2023.

SEC source: 0001562180-22-003531 · primarydocument.xml · derivative · entry 1

DOYLE MICHAEL A · CIK 0001284533 · CFO and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,629

Underlying: Common Stock · 31,629 shares

Expires 2032-04-07

F1 · derivative.exercise_date: The option vests as to 25% of the shares on April 7, 2023, and the remaining 75% vests in 36 equal monthly installments at the end of each month beginning on July 31, 2023.

SEC source: 0001562180-22-003221 · primarydocument.xml · nonDerivative · entry 1

MEISTER PAUL M · CIK 0001033876 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,414

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the first quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on April 1, 2022.

F3 · balance_after: Includes 2,668 restricted stock units.

SEC source: 0001562180-22-003220 · primarydocument.xml · nonDerivative · entry 1

Hlavinka Sarah E. · CIK 0001433554 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,291

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the first quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on April 1, 2022.

F3 · balance_after: Includes 2,668 restricted stock units

SEC source: 0001562180-22-003217 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,229

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $29.25 to $30.00. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 14,299 restricted stock units.

SEC source: 0001562180-22-003219 · primarydocument.xml · nonDerivative · entry 1

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 886,976

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $29.25 to $30.00. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 39,214 restricted stock units and 39,815 shares of common stock that are subject to performance based vesting.

SEC source: 0001562180-22-003261 · primarydocument.xml · nonDerivative · entry 1

CRANDELL KEITH · CIK 0001219039 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,749

F1 · shares: Consists of stock granted in lieu of cash fees for service on the Company's Board of Directors and committees thereof for the first quarter of 2022.

F2 · price: Closing price of the Company's common stock on the Nasdaq Global Market on April 1, 2022.

F3 · balance_after: Includes 2,668 restricted stock units.

SEC source: 0001562180-22-003218 · primarydocument.xml · nonDerivative · entry 1

Roskey Mark T. · CIK 0001724565 · SVP, Strategic Partnerships

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,325

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 542 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $29.25 to $30.00. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 8,062 restricted stock units.

SEC source: 0001562180-22-003216 · primarydocument.xml · nonDerivative · entry 1

Mattoon Dawn · CIK 0001731785 · Sr. VP, Diagnostics

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,876

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 618 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $29.25 to $30.00. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 9,549 restricted stock units.

SEC source: 0001562180-22-002952 · primarydocument.xml · nonDerivative · entry 1

Duffy David C. · CIK 0001724566 · SVP R&D and CTO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,730

F1 · shares: The sale of shares reported on this Form 4 was made pursuant to a Rule 10b5-1 trading plan adopted on November 16, 2021.

F2 · balance_after: Includes 7,287 restricted stock units.

SEC source: 0001562180-22-002274 · primarydocument.xml · nonDerivative · entry 2

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,753

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F3 · balance_after: Includes 15,075 restricted stock units.

SEC source: 0001562180-22-002274 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,852

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 776 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $30.84 to $31.83. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 15,075 restricted stock units.

SEC source: 0001562180-22-002275 · primarydocument.xml · nonDerivative · entry 2

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 887,844

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F3 · balance_after: Includes 41,282 restricted stock units.

SEC source: 0001562180-22-002275 · primarydocument.xml · nonDerivative · entry 1

HRUSOVSKY E KEVIN · CIK 0001252546 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 888,002

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 2,068 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $30.84 to $31.83. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 41,282 restricted stock units.

SEC source: 0001562180-22-002276 · primarydocument.xml · nonDerivative · entry 2

Roskey Mark T. · CIK 0001724565 · SVP, Strategic Partnerships

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,496

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 542 RSUs.

F3 · balance_after: Includes 8,604 restricted stock units.

SEC source: 0001562180-22-002276 · primarydocument.xml · nonDerivative · entry 1

Roskey Mark T. · CIK 0001724565 · SVP, Strategic Partnerships

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,540

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 542 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $30.84 to $31.83. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 8,604 restricted stock units.

SEC source: 0001562180-22-002273 · primarydocument.xml · nonDerivative · entry 2

Mattoon Dawn · CIK 0001731785 · Sr. VP, Diagnostics

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,137

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 618 RSUs.

F3 · balance_after: Includes 10,167 restricted stock units.

SEC source: 0001562180-22-002273 · primarydocument.xml · nonDerivative · entry 1

Mattoon Dawn · CIK 0001731785 · Sr. VP, Diagnostics

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,208

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 618 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $30.84 to $31.83. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 10,167 restricted stock units.

SEC source: 0001562180-22-001275 · primarydocument.xml · nonDerivative · entry 1

Fry John J · CIK 0001419544 · General Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,124

F1 · shares: The sales of shares reported on this Form 4 were made solely to cover tax obligations upon the vesting of 919 RSUs.

F2 · price: This transaction was executed in multiple trades at prices ranging from $34.9435 to $34.985. The price reported reflects the weighted average sale price. The reporting person undertakes to provide upon request to the SEC staff, the issuer or any security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · balance_after: Includes 15,851 restricted stock units.