PTCT

SEC source: 0001288952-26-000002 · form4-01062026_050106.xml · derivative · entry 2

SCHMERTZLER MICHAEL · CIK 0001288952 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,950

Underlying: Common Stock · 6,950 shares

Expires 2036-01-01

F2 · derivative.exercise_date: This option was granted on January 2, 2026 and vests over one year in twelve equal monthly installments, commencing on February 2, 2026.

SEC source: 0001288952-26-000002 · form4-01062026_050106.xml · nonDerivative · entry 1

SCHMERTZLER MICHAEL · CIK 0001288952 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 163,266

F1 · shares: Restricted stock units granted on January 2, 2026 that vest over one year, with five-twelfths (5/12) of the shares underlying the RSUs vesting on June 2, 2026 and the remaining seven-twelfths (7/12) of the original shares underlying the RSUs vesting on January 2, 2027.

SEC source: 0001984065-26-000002 · form4-01062026_050105.xml · derivative · entry 2

Gravier Pierre · CIK 0001984065 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2036-01-01

F3 · derivative.exercise_date: This option was granted on January 2, 2026, and vests over four years, with 25% of the shares underlying the option vesting on January 2, 2027, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 2, 2027.

SEC source: 0001984065-26-000002 · form4-01062026_050105.xml · nonDerivative · entry 1

Gravier Pierre · CIK 0001984065 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,449

F1 · shares: Restricted stock units granted on January 2, 2026 that vest in four equal installments over four years, commencing on January 2, 2027.

F2 · balance_after: Includes 272 shares of common stock acquired under the Issuer's employee stock purchase plan for the period ended June 30, 2025, and 257 shares of common stock acquired under the Issuer's employee stock purchase plan for the period ended December 31, 2025.

SEC source: 0001808968-26-000003 · form4-01062026_050103.xml · derivative · entry 2

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 157,500

Underlying: Common Stock · 157,500 shares

Expires 2036-01-01

F3 · derivative.exercise_date: This option was granted on January 2, 2026, and vests over four years, with 25% of the shares underlying the option vesting on January 2, 2027, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 2, 2027.

SEC source: 0001808968-26-000003 · form4-01062026_050103.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 405,132

F1 · shares: Restricted stock units granted on January 2, 2026 that vest in four equal installments over four years, commencing on January 2, 2027.

F2 · balance_after: Includes 257 shares of common stock acquired under the Issuer's employee stock purchase plan for the period ended December 31, 2025.

SEC source: 0001269131-26-000003 · form4-01062026_050101.xml · derivative · entry 5

STEELE GLENN JR MD PHD · CIK 0001269131 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,475

Underlying: Common Stock · 3,475 shares

Expires 2036-01-01

F4 · derivative.exercise_date: This option was granted on January 2, 2026 and vests over one year in twelve equal monthly installments, commencing on February 2, 2026.

SEC source: 0001269131-26-000003 · form4-01062026_050101.xml · derivative · entry 4

STEELE GLENN JR MD PHD · CIK 0001269131 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 12,000 shares

Expires 2026-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 8, 2025.

F3 · derivative.exercise_date: Currently exercisable.

SEC source: 0001269131-26-000003 · form4-01062026_050101.xml · nonDerivative · entry 3

STEELE GLENN JR MD PHD · CIK 0001269131 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,500

F2 · shares: Restricted stock units granted on January 2, 2026 that vest over one year, with five-twelfths (5/12) of the shares underlying the RSUs vesting on June 2, 2026 and the remaining seven-twelfths (7/12) of the original shares underlying the RSUs vesting on January 2, 2027.

SEC source: 0001269131-26-000003 · form4-01062026_050101.xml · nonDerivative · entry 2

STEELE GLENN JR MD PHD · CIK 0001269131 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,500

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 8, 2025.

SEC source: 0001269131-26-000003 · form4-01062026_050101.xml · nonDerivative · entry 1

STEELE GLENN JR MD PHD · CIK 0001269131 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 8, 2025.

SEC source: 0001808968-26-000001 · form4-01022026_050101.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 341,875

F1 · shares: Represents shares automatically sold pursuant to an irrevocable sell to cover election to satisfy tax withholding obligations in connection with the vesting of 18,750 RSUs from a December 28, 2023 grant of 75,000 RSUs.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · derivative · entry 16

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 19,805 shares

Expires 2031-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F12 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · derivative · entry 15

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,566

Underlying: Common Stock · 565 shares

Expires 2028-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F12 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · derivative · entry 14

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,805

Underlying: Common Stock · 138 shares

Expires 2031-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F12 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 13

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F11 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.13 to $78.56 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 12

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,593

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F10 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $77.10 to $78.02 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 11

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,141

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F9 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $76.05 to $76.77 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 10

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 88,678

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F8 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.05 to $76.01 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 9

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 90,178

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 8

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F7 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.34 to $78.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 7

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,432

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F6 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $77.25 to $78.22 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 6

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,745

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F5 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.04 to $75.91 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 5

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,938

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 4

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F4 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $77.65 to $78.52 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 3

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,432

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $76.60 to $77.55 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 2

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,474

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.20 to $76.08 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000006 · form4-12232025_051201.xml · nonDerivative · entry 1

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,511

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · derivative · entry 18

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,131

Underlying: Common Stock · 251 shares

Expires 2028-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F7 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · derivative · entry 17

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,943

Underlying: Common Stock · 2,951 shares

Expires 2031-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F7 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 14

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F6 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.20 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 13

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,204

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 12

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 11

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,624

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 10

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F5 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.18 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 9

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,493

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · derivative · entry 16

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,382

Underlying: Common Stock · 3,684 shares

Expires 2028-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F7 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · derivative · entry 15

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,894

Underlying: Common Stock · 36,606 shares

Expires 2031-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F7 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 8

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 7

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,473

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F4 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 6

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,734

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 5

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,373

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 4

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,473

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 3

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 74,157

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 2

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 72,912

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.55 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001323212-25-000003 · form4-12192025_051201.xml · nonDerivative · entry 1

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 74,157

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.

SEC source: 0001288952-25-000004 · form4-12182025_051201.xml · derivative · entry 2

SCHMERTZLER MICHAEL · CIK 0001288952 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,000 shares

Expires 2026-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Currently exercisable.

SEC source: 0001288952-25-000004 · form4-12182025_051201.xml · nonDerivative · entry 1

SCHMERTZLER MICHAEL · CIK 0001288952 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 155,266

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001680329-25-000014 · form4-12052025_051201.xml · derivative · entry 3

Reeve Emma · CIK 0001680329 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 734

Underlying: Common Stock · 733 shares

Expires 2035-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 4, 2025.

F2 · derivative.exercise_date: This option was granted on January 3, 2025 and vests over one year in twelve equal monthly installments, commencing on February 3, 2025.

SEC source: 0001680329-25-000014 · form4-12052025_051201.xml · nonDerivative · entry 2

Reeve Emma · CIK 0001680329 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,666

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 4, 2025.