PTCT

SEC source: 0001578850-26-000014 · form4-06242026_050601.xml · derivative · entry 5

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,751

Underlying: Common Stock · 23,749 shares

Expires 2034-02-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

F4 · derivative.exercise_date: This option was granted on February 15, 2024, and vests over four years, with 25% of the shares underlying the option vesting on February 15, 2025, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on May 15, 2025.

SEC source: 0001578850-26-000014 · form4-06242026_050601.xml · nonDerivative · entry 3

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,137

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $81.00 to $81.57 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578850-26-000014 · form4-06242026_050601.xml · nonDerivative · entry 2

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,756

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $80.00 to $80.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578850-26-000014 · form4-06242026_050601.xml · nonDerivative · entry 1

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 83,886

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

SEC source: 0001707685-26-000010 · form4-06222026_050603.xml · derivative · entry 3

Utter Christine Marie · CIK 0001707685 · SVP, CHIEF ACCOUNTING OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,314

Underlying: Common Stock · 19,686 shares

Expires 2034-02-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 17, 2026.

F2 · derivative.exercise_date: This option was granted on February 15, 2024, and vests over four years, with 25% of the shares underlying the option vesting on February 15, 2025, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on May 15, 2025.

SEC source: 0001707685-26-000010 · form4-06222026_050603.xml · nonDerivative · entry 2

Utter Christine Marie · CIK 0001707685 · SVP, CHIEF ACCOUNTING OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,199

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 17, 2026.

SEC source: 0001707685-26-000010 · form4-06222026_050603.xml · nonDerivative · entry 1

Utter Christine Marie · CIK 0001707685 · SVP, CHIEF ACCOUNTING OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 89,885

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 17, 2026.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · derivative · entry 8

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,938

Underlying: Common Stock · 2,012 shares

Expires 2035-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F5 · derivative.exercise_date: This option was granted on January 3, 2025, and vests over four years, with 25% of the shares underlying the option vesting on January 3, 2026, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 3, 2026.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · derivative · entry 7

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,950

Underlying: Common Stock · 8,510 shares

Expires 2035-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F5 · derivative.exercise_date: This option was granted on January 3, 2025, and vests over four years, with 25% of the shares underlying the option vesting on January 3, 2026, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 3, 2026.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · nonDerivative · entry 6

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,272

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F4 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $79.00 to $79.48 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · nonDerivative · entry 5

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,581

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.00 to $78.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · nonDerivative · entry 4

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 107,284

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · nonDerivative · entry 3

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,272

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $79.00 to $79.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · nonDerivative · entry 2

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 107,122

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.00 to $78.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000018 · form4-06222026_050601.xml · nonDerivative · entry 1

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 113,722

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001323212-26-000010 · form4-06122026_050610.xml · derivative · entry 4

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,566 shares

Expires 2028-01-02

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on February 25, 2026.

F2 · derivative.exercise_date: Currently exercisable.

SEC source: 0001323212-26-000010 · form4-06122026_050610.xml · nonDerivative · entry 3

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,411

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on February 25, 2026.

SEC source: 0001323212-26-000010 · form4-06122026_050610.xml · nonDerivative · entry 2

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 90,977

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on February 25, 2026.

SEC source: 0001323212-26-000010 · form4-06122026_050610.xml · nonDerivative · entry 1

Pauwels Eric · CIK 0001323212 · CHIEF BUSINESS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,411

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on February 25, 2026.

SEC source: 0001578852-26-000016 · form4-05192026_050501.xml · derivative · entry 4

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,689

Underlying: Common Stock · 2,812 shares

Expires 2034-02-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F4 · derivative.exercise_date: This option was granted on February 15, 2024, and vests over four years, with 25% of the shares underlying the option vesting on February 15, 2025, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on May 15, 2025.

SEC source: 0001578852-26-000016 · form4-05192026_050501.xml · nonDerivative · entry 3

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,212

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $72.41 to $72.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000016 · form4-05192026_050501.xml · nonDerivative · entry 2

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,668

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $71.41 to $72.29 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000016 · form4-05192026_050501.xml · nonDerivative · entry 1

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 108,024

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001808968-26-000015 · form4-05152026_050501.xml · nonDerivative · entry 5

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 393,998

F2 · kind: Represents shares automatically sold pursuant to an irrevocable sell to cover election entered into upon acceptance of the RSU grant to satisfy tax withholding obligations in connection with the vesting of the earned RSUs with respect to 6,250 shares on May 13, 2026.

SEC source: 0001808968-26-000015 · form4-05152026_050501.xml · nonDerivative · entry 4

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 396,570

SEC source: 0001808968-26-000015 · form4-05152026_050501.xml · nonDerivative · entry 3

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 398,670

SEC source: 0001808968-26-000015 · form4-05152026_050501.xml · nonDerivative · entry 2

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 405,891

SEC source: 0001808968-26-000015 · form4-05152026_050501.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 406,570

F1 · kind: Represents the number of shares of the Issuer's common stock underlying restricted stock units ("RSUs") earned upon the vesting of performance-based restricted stock units ("PSUs") granted in December 2024. The Issuer's compensation committee of the board of directors certified the Issuer's achievement of a pre-established milestone set forth in the PSUs, as of May 13, 2026, which resulted in the reported RSUs being earned. Each earned RSU represents the contingent right to receive one share of the Issuer's common stock upon vesting. The earned RSUs immediately vested as to 6,250 shares on May 13, 2026 in connection with being earned and are scheduled to vest with respect to the remaining 6,250 shares on May 13, 2027.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · derivative · entry 8

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,460

Underlying: Common Stock · 800 shares

Expires 2035-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F5 · derivative.exercise_date: This option was granted on January 3, 2025, and vests over four years, with 25% of the shares underlying the option vesting on January 3, 2026, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 3, 2026.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · derivative · entry 7

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 42,260

Underlying: Common Stock · 2,740 shares

Expires 2035-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F5 · derivative.exercise_date: This option was granted on January 3, 2025, and vests over four years, with 25% of the shares underlying the option vesting on January 3, 2026, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 3, 2026.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · nonDerivative · entry 6

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,212

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F4 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $79.02 to $79.52 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · nonDerivative · entry 5

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,812

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · nonDerivative · entry 4

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,012

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · nonDerivative · entry 3

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,212

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $79.03 to $79.70 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · nonDerivative · entry 2

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 107,112

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.00 to $78.72 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000014 · form4-05122026_050501.xml · nonDerivative · entry 1

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 107,952

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001808968-26-000013 · form4-04232026_050401.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 394,070

F1 · shares: Represents shares automatically sold pursuant to an irrevocable sell to cover election entered into upon acceptance of the grant to satisfy tax withholding obligations in connection with the vesting of 6,500 RSUs from an April 18, 2023 grant of 26,000 RSUs.

SEC source: 0001578852-26-000012 · form4-04082026_050401.xml · derivative · entry 4

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,798

Underlying: Common Stock · 2,265 shares

Expires 2033-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F4 · derivative.exercise_date: This option was granted on January 5, 2023 and vests over four years, with 25% of the shares underlying the option vesting on January 5, 2024, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 5, 2024.

SEC source: 0001578852-26-000012 · form4-04082026_050401.xml · nonDerivative · entry 3

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,212

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $69.30 to $70.25 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000012 · form4-04082026_050401.xml · nonDerivative · entry 2

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,655

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $68.24 to $69.17 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578852-26-000012 · form4-04082026_050401.xml · nonDerivative · entry 1

Boulding Mark Elliott · CIK 0001578852 · EXEC. VP AND CLO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 107,477

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 10, 2025.

SEC source: 0001686217-26-000012 · form4-04062026_050401.xml · nonDerivative · entry 1

Golden Lee Scott · CIK 0001686217 · EVP & CHIEF MEDICAL OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 79,115

F1 · kind: Represents shares automatically sold pursuant to an irrevocable sell to cover election entered into upon acceptance of the grant to satisfy tax withholding obligations in connection with the vesting of 2,100 RSUs from an April 24, 2023 grant of 8,400 RSUs.

SEC source: 0001578850-26-000012 · form4-04032026_050402.xml · nonDerivative · entry 3

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,137

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

SEC source: 0001578850-26-000012 · form4-04032026_050402.xml · nonDerivative · entry 2

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,217

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $69.26 to $70.13 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001578850-26-000012 · form4-04032026_050402.xml · nonDerivative · entry 1

Almstead Neil Gregory · CIK 0001578850 · CHIEF TECHNICAL OPS OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 72,747

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on November 11, 2025.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $68.26 to $69.26 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0002123815-26-000004 · form4-03262026_110330.xml · derivative · entry 4

Chutter Jessica Caroline · CIK 0002123815 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,896

Underlying: Common Stock · 2,896 shares

Expires 2036-03-23

F4 · derivative.exercise_date: This option was granted on March 24, 2026 and vests over 10 equal monthly installments, commencing on April 2, 2026.

SEC source: 0002123815-26-000004 · form4-03262026_110330.xml · derivative · entry 3

Chutter Jessica Caroline · CIK 0002123815 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,475

Underlying: Common Stock · 3,475 shares

Expires 2036-03-23

F3 · derivative.exercise_date: This option was granted on March 24, 2026 and vests over 36 equal monthly installments, commencing on April 24, 2026.

SEC source: 0002123815-26-000004 · form4-03262026_110330.xml · nonDerivative · entry 2

Chutter Jessica Caroline · CIK 0002123815 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,333

F2 · shares: Restricted stock units granted on March 24, 2026 that vest with respect to 1,000 shares underlying such restricted stock units on June 2, 2026, and with respect to the remaining 2,333 shares on January 2, 2027.

SEC source: 0002123815-26-000004 · form4-03262026_110330.xml · nonDerivative · entry 1

Chutter Jessica Caroline · CIK 0002123815 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,000

F1 · shares: Restricted stock units granted on March 24, 2026 that vest in three equal annual installments, commencing on March 24, 2027.

SEC source: 0001808968-26-000011 · form4-03132026_050301.xml · nonDerivative · entry 2

Klein Matthew B. · CIK 0001808968 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 396,920

F2 · kind: Represents shares automatically sold pursuant to an irrevocable sell to cover election entered into upon acceptance of the RSU grant to satisfy tax withholding obligations in connection with the vesting of the earned RSUs with respect to 6,500 shares on March 11, 2026.