PTCT

SEC source: 0001179110-21-000733 · edgar.xml · derivative · entry 3

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 86,314

Underlying: Common Stock · 4,300 shares

Expires 2029-10-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

F3 · derivative.exercise_date: This option was granted on October 25, 2019, and vests over four years, with 25% of the shares underlying the option vesting on October 28, 2020, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on January 28, 2021.

SEC source: 0001179110-21-000733 · edgar.xml · nonDerivative · entry 2

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,309

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $68.98 to $69.28 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001179110-21-000733 · edgar.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,609

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

SEC source: 0001179110-21-000648 · edgar.xml · derivative · entry 7

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 2,500 shares

Expires 2028-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

F3 · derivative.exercise_date: This option was granted on January 3, 2018, and vests over four years, with 25% of the shares underlying the option vesting on January 3, 2019, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 3, 2019.

SEC source: 0001179110-21-000648 · edgar.xml · derivative · entry 6

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 788 shares

Expires 2027-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

F2 · derivative.exercise_date: Currently exercisable.

SEC source: 0001179110-21-000648 · edgar.xml · nonDerivative · entry 5

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,529

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

SEC source: 0001179110-21-000648 · edgar.xml · nonDerivative · entry 4

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,029

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

SEC source: 0001179110-21-000648 · edgar.xml · nonDerivative · entry 3

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,529

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

SEC source: 0001179110-21-000648 · edgar.xml · nonDerivative · entry 2

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,317

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

SEC source: 0001179110-21-000648 · edgar.xml · nonDerivative · entry 1

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,529

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person on December 14, 2020.

SEC source: 0001179110-21-000540 · edgar.xml · derivative · entry 3

Almstead Neil Gregory · CIK 0001578850 · Chief Technical Ops Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 0

Underlying: Common Stock · 1,300 shares

Expires 2024-01-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the spouse of the Reporting Person on November 10, 2020.

F2 · derivative.exercise_date: Currently exercisable.

SEC source: 0001179110-21-000540 · edgar.xml · nonDerivative · entry 2

Almstead Neil Gregory · CIK 0001578850 · Chief Technical Ops Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 2,388

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the spouse of the Reporting Person on November 10, 2020.

SEC source: 0001179110-21-000540 · edgar.xml · nonDerivative · entry 1

Almstead Neil Gregory · CIK 0001578850 · Chief Technical Ops Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 3,688

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the spouse of the Reporting Person on November 10, 2020.

SEC source: 0001179110-21-000539 · edgar.xml · derivative · entry 4

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,614

Underlying: Common Stock · 5,500 shares

Expires 2029-10-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

F4 · derivative.exercise_date: This option was granted on October 25, 2019, and vests over four years, with 25% of the shares underlying the option vesting on October 28, 2020, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on January 28, 2021.

SEC source: 0001179110-21-000539 · edgar.xml · nonDerivative · entry 3

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,309

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

F3 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $70.00 to $70.61 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001179110-21-000539 · edgar.xml · nonDerivative · entry 2

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,809

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

F2 · price: This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $68.98 to $69.93 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

SEC source: 0001179110-21-000539 · edgar.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,809

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · derivative · entry 12

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,932

Underlying: Common Stock · 9,278 shares

Expires 2029-01-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

F4 · derivative.exercise_date: This option was granted on January 22, 2019 and vests over four years, with 25% of the shares underlying the option vesting on January 22, 2020, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning April 22, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · derivative · entry 11

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,500

Underlying: Common Stock · 10,500 shares

Expires 2028-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

F3 · derivative.exercise_date: This option was granted on January 3, 2018, and vests over four years, with 25% of the shares underlying the option vesting on January 3, 2019, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 3, 2019.

SEC source: 0001179110-21-000538 · edgar.xml · derivative · entry 10

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,825 shares

Expires 2027-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

F2 · derivative.exercise_date: Currently exercisable.

SEC source: 0001179110-21-000538 · edgar.xml · derivative · entry 9

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,430 shares

Expires 2026-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

F2 · derivative.exercise_date: Currently exercisable.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 8

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,122

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 7

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,400

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 6

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,122

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 5

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,622

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 4

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,122

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 3

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,947

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 2

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,122

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000538 · edgar.xml · nonDerivative · entry 1

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,552

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to written a Rule 10b5-1 plan adopted by the Reporting Person on May 20, 2020.

SEC source: 0001179110-21-000467 · edgar.xml · derivative · entry 5

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,114

Underlying: Common Stock · 3,886 shares

Expires 2029-10-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

F5 · derivative.exercise_date: This option was granted on October 25, 2019, and vests over four years, with 25% of the shares underlying the option vesting on October 28, 2020, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on January 28, 2021.

SEC source: 0001179110-21-000467 · edgar.xml · nonDerivative · entry 3

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,309

F3 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

SEC source: 0001179110-21-000467 · edgar.xml · nonDerivative · entry 2

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on December 2, 2020.

SEC source: 0001179110-21-000474 · edgar.xml · derivative · entry 2

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,000

Underlying: Common Stock · 63,000 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000474 · edgar.xml · nonDerivative · entry 1

Hill Emily Luisa · CIK 0001778279 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,122

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000473 · edgar.xml · derivative · entry 2

Boulding Mark Elliott · CIK 0001578852 · Exec. VP and CLO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,500

Underlying: Common Stock · 59,500 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000473 · edgar.xml · nonDerivative · entry 1

Boulding Mark Elliott · CIK 0001578852 · Exec. VP and CLO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,152

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000472 · edgar.xml · derivative · entry 2

Pauwels Eric · CIK 0001323212 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,500

Underlying: Common Stock · 59,500 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000472 · edgar.xml · nonDerivative · entry 1

Pauwels Eric · CIK 0001323212 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,280

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000470 · edgar.xml · derivative · entry 4

Peltz Stuart Walter · CIK 0001578962 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 23,100

Underlying: Common Stock · 23,100 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000470 · edgar.xml · derivative · entry 3

Peltz Stuart Walter · CIK 0001578962 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 161,000

Underlying: Common Stock · 161,000 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000470 · edgar.xml · nonDerivative · entry 2

Peltz Stuart Walter · CIK 0001578962 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 15,714

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000470 · edgar.xml · nonDerivative · entry 1

Peltz Stuart Walter · CIK 0001578962 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,283

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000468 · edgar.xml · derivative · entry 2

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,750

Underlying: Common Stock · 50,750 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000468 · edgar.xml · nonDerivative · entry 1

Utter Christine Marie · CIK 0001707685 · SVP, Finance & CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,188

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000467 · edgar.xml · derivative · entry 4

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,500

Underlying: Common Stock · 52,500 shares

Expires 2031-01-05

F4 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000467 · edgar.xml · nonDerivative · entry 1

Klein Matthew B. · CIK 0001808968 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,309

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

F2 · balance_after: Includes 155 shares of common stock acquired under the Issuer's employee stock purchase plan for the period ending June 30, 2020 and 154 shares of common stock acquired under the Issuer's employee stock purchase plan for the period ending December 31, 2020.

SEC source: 0001179110-21-000466 · edgar.xml · derivative · entry 3

Almstead Neil Gregory · CIK 0001578850 · Chief Technical Ops Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,500

Underlying: Common Stock · 59,500 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021, and vests over four years, with 25% of the shares underlying the option vesting on January 6, 2022, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 6, 2022.

SEC source: 0001179110-21-000466 · edgar.xml · nonDerivative · entry 2

Almstead Neil Gregory · CIK 0001578850 · Chief Technical Ops Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 2,388

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000466 · edgar.xml · nonDerivative · entry 1

Almstead Neil Gregory · CIK 0001578850 · Chief Technical Ops Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,787

F1 · shares: Restricted stock units granted on January 6, 2021 that vest in four equal installments over four years, commencing on January 6, 2022.

SEC source: 0001179110-21-000465 · edgar.xml · derivative · entry 2

Reeve Emma · CIK 0001680329 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2031-01-05

F2 · derivative.exercise_date: This option was granted on January 6, 2021 and vests over one year in twelve equal monthly installments, commencing on February 6, 2021.