PI

SEC source: 0001209191-22-050649 · doc4.xml · nonDerivative · entry 3

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,097

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $88.32 to $88.40, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050649 · doc4.xml · nonDerivative · entry 2

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,217

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $87.1401 to $88.14, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050647 · doc4.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,946

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $88.16 to $88.38, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050647 · doc4.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300,066

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $87.1401 to $88.14, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050644 · doc4.xml · nonDerivative · entry 3

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,569

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $88.17 to $88.405, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050644 · doc4.xml · nonDerivative · entry 2

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,629

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $87.1401 to $88.14, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050652 · doc4.xml · derivative · entry 6

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,282

Underlying: Common Stock · 468 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F6 · derivative.exercise_date: On June 29, 2020, the reporting person was granted 7,500 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

F6 · derivative.expiration_date: On June 29, 2020, the reporting person was granted 7,500 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

SEC source: 0001209191-22-050652 · doc4.xml · derivative · entry 5

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,469

Underlying: Common Stock · 781 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On June 15, 2020, the reporting person was granted 12,500 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

F5 · derivative.expiration_date: On June 15, 2020, the reporting person was granted 12,500 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

SEC source: 0001209191-22-050652 · doc4.xml · nonDerivative · entry 2

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,253

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-050652 · doc4.xml · nonDerivative · entry 1

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,785

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-050649 · doc4.xml · derivative · entry 4

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,125

Underlying: Common Stock · 1,875 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On June 15, 2020, the reporting person was granted 30,000 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

F5 · derivative.expiration_date: On June 15, 2020, the reporting person was granted 30,000 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

SEC source: 0001209191-22-050649 · doc4.xml · nonDerivative · entry 1

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,874

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-050647 · doc4.xml · derivative · entry 5

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,938

Underlying: Common Stock · 1,562 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On June 15, 2020, the reporting person was granted 25,000 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

F5 · derivative.expiration_date: On June 15, 2020, the reporting person was granted 25,000 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

SEC source: 0001209191-22-050647 · doc4.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300,593

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-050644 · doc4.xml · derivative · entry 4

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,469

Underlying: Common Stock · 781 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On June 15, 2020, the reporting person was granted 12,500 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

F5 · derivative.expiration_date: On June 15, 2020, the reporting person was granted 12,500 restricted stock units ("RSUs"), one fourth of which vested on June 15, 2021, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on September 15, 2022.

SEC source: 0001209191-22-050644 · doc4.xml · nonDerivative · entry 1

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,893

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-049348 · doc4.xml · nonDerivative · entry 1

SESSLER GREGORY · CIK 0001285810 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,907

F1 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $92.12 to $92.165, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-048775 · doc4.xml · nonDerivative · entry 1

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,999

F1 · kind: The sales reported by Mr. Dossett were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

SEC source: 0001209191-22-047718 · doc4.xml · nonDerivative · entry 2

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,112

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of RSUs.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $95.055 to $95.925, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-047718 · doc4.xml · derivative · entry 3

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Stock · 3,750 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F4 · derivative.exercise_date: On February 24, 2020, the reporting person was granted 60,000 restricted stock units ("RSUs"), one sixteenth of which vested on August 24, 2022.

F4 · derivative.expiration_date: On February 24, 2020, the reporting person was granted 60,000 restricted stock units ("RSUs"), one sixteenth of which vested on August 24, 2022.

SEC source: 0001209191-22-047718 · doc4.xml · nonDerivative · entry 1

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,564

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 7

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,031

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 6

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,081

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $92.71 to $93.68, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 5

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 301,084

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $91.64 to $92.56, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 4

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 304,031

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F5 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $93.32 to $94.05, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 304,776

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $92.20 to $93.13, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 306,011

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $91.15 to $92.05, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-047249 · doc4.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 308,231

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $90.01 to $91.00, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 7

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 309,031

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $96.43 to $96.715, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 6

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 309,481

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $95.43 to $96.415, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 5

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 311,544

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F5 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $94.43 to $95.425, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 4

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 313,030

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $93.43 to $94.395, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 314,031

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 314,231

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $96.22 to $97.15, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-046636 · doc4.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 317,350

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $95.21 to $96.20, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-044330 · doc4.xml · derivative · entry 3

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,384

Underlying: Common Stock · 9,000 shares

Expires 2028-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: One-fourth of the shares subject to the option vested on December 5, 2019, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-044330 · doc4.xml · nonDerivative · entry 2

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,004

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $89.00 to $89.06, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-044330 · doc4.xml · nonDerivative · entry 1

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,004

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-044328 · doc4.xml · derivative · entry 3

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,500

Underlying: Common Stock · 3,000 shares

Expires 2030-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: One-fourth of the shares subject to the option shall vest on June 15, 2021, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-044328 · doc4.xml · nonDerivative · entry 2

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,814

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $90.00 to $90.14, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-044328 · doc4.xml · nonDerivative · entry 1

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,814

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-043782 · doc4.xml · derivative · entry 20

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,594

Underlying: Common Stock · 156 shares

Expires 2030-06-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: One-fourth of the shares subject to the option vested on June 15, 2021, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-043782 · doc4.xml · derivative · entry 19

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,990

Underlying: Common Stock · 260 shares

Expires 2030-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: One-fourth of the shares subject to the option vested on June 15, 2021, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-043782 · doc4.xml · derivative · entry 18

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

Underlying: Common Stock · 209 shares

Expires 2029-07-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: One-fourth of the shares subject to the option vested July 31, 2020, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-043782 · doc4.xml · nonDerivative · entry 12

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,004

F2 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $85.27 to $85.53, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-043782 · doc4.xml · nonDerivative · entry 11

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,250

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

SEC source: 0001209191-22-043782 · doc4.xml · nonDerivative · entry 10

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-043782 · doc4.xml · nonDerivative · entry 9

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,719

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-043782 · doc4.xml · nonDerivative · entry 8

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,459

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-043940 · doc4.xml · nonDerivative · entry 3

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,999

F3 · kind: The sales reported by Mr. Dossett were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.