PI

SEC source: 0001209191-22-054933 · doc4.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,733

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $108.55 to $109.31, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · derivative · entry 8

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2030-09-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option was approved on September 18, 2020 by the Compensation Committee of the Issuer's Board of Directors in connection with certain consulting services being provided by the Reporting Person. The Option fully vested on October 21, 2022.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 7

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,073

F1 · kind: The sales reported by Mr. Phelan were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $112.94 to $113.58, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 6

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,637

F1 · kind: The sales reported by Mr. Phelan were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $111.89 to $112.74, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 5

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,337

F1 · kind: The sales reported by Mr. Phelan were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F5 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $110.88 to $111.86, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 4

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,173

F1 · kind: The sales reported by Mr. Phelan were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $109.85 to $110.81, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 3

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,173

F1 · kind: The sales reported by Mr. Phelan were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $108.70 to $109.57, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 2

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,873

F1 · kind: The sales reported by Mr. Phelan were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $107.53 to $108.47, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055135 · doc4.xml · nonDerivative · entry 1

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,073

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-055132 · doc4.xml · derivative · entry 8

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,384

Underlying: Common Stock · 9,000 shares

Expires 2028-12-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: One-fourth of the shares subject to the option vested on December 5, 2019, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 7

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,401

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $112.75 to $113.58, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 6

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,965

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $111.50 to $112.49, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 5

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,194

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F5 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $110.50 to 111.47, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 4

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,753

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $109.47 to $110.46, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 3

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,251

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $108.47 to $109.37, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 2

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,501

F1 · kind: The sales reported by Mr. Mecklai were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $107.42 to $108.40, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055132 · doc4.xml · nonDerivative · entry 1

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,401

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-055130 · doc4.xml · derivative · entry 8

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,500

Underlying: Common Stock · 3,000 shares

Expires 2030-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: One-fourth of the shares subject to the option vested on June 15, 2021, and 1/48th of the shares subject to the option shall vest each month thereafter, subject to the Reporting Person's continued service to the Issuer through such date.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 7

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,266

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $112.94 to $113.58, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 6

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,583

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $111.815 to $112.46, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 5

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,189

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F5 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $110.78 to $111.76, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 4

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,461

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $109.755 to $110.73, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 3

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,189

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $108.70 to $109.61, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 2

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,591

F1 · kind: The sales reported by Mr. Baker were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $107.54 to $108.47, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-055130 · doc4.xml · nonDerivative · entry 1

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,141

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-054933 · doc4.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,307

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2022.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $108.09 to $109.00, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053678 · doc4.xml · nonDerivative · entry 3

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,401

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $79.62 to $80.2301, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053678 · doc4.xml · nonDerivative · entry 2

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,548

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $78.57 to $79.41, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053673 · doc4.xml · nonDerivative · entry 3

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,859

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $79.59 to $80.2301, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053673 · doc4.xml · nonDerivative · entry 2

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,997

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $78.57 to $79.45, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053668 · doc4.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 304,307

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $79.62 to $80.2301, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053668 · doc4.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 304,590

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $78.56 to $79.52, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053666 · doc4.xml · nonDerivative · entry 3

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,141

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $79.62 to $80.2301, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053666 · doc4.xml · nonDerivative · entry 2

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,237

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $78.58 to $79.39, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-053678 · doc4.xml · derivative · entry 4

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,938

Underlying: Common Stock · 1,094 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 17,500 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 17,500 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

SEC source: 0001209191-22-053678 · doc4.xml · nonDerivative · entry 1

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,828

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-053673 · doc4.xml · derivative · entry 4

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 1,250 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 20,000 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 20,000 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

SEC source: 0001209191-22-053673 · doc4.xml · nonDerivative · entry 1

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,347

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-053668 · doc4.xml · derivative · entry 5

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,250

Underlying: Common Stock · 3,125 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 50,000 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 50,000 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

SEC source: 0001209191-22-053668 · doc4.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 305,525

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-053666 · doc4.xml · derivative · entry 4

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,375

Underlying: Common Stock · 938 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 15,000 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 15,000 restricted stock units ("RSUs"), one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 12, 2022.

SEC source: 0001209191-22-053666 · doc4.xml · nonDerivative · entry 1

Baker Cary · CIK 0001705407 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,507

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-052738 · doc4.xml · nonDerivative · entry 1

DOSSETT JEFFREY · CIK 0001578147 · Chief Revenue Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,097

F1 · kind: The sales reported by Mr. Dossett were effected pursuant to a Rule 10b5-1 trading plan effective on February 11, 2022.

SEC source: 0001209191-22-052732 · doc4.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 302,400

SEC source: 0001209191-22-052732 · doc4.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 302,460

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $84.2301 to $85.10, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-051867 · doc4.xml · derivative · entry 1

PHELAN CATHAL G · CIK 0001259761 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common Stock · 8,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of Impinj common stock.

F2 · derivative.exercise_date: The RSUs were approved by the Compensation Committee of the Issuer's Board of Directors in connection with certain consulting services being provided by the Reporting Person. 25% of the RSUs will vest on each of January 1, 2023, April 1, 2023, July 1, 2023 and October 1, 2023, subject in each case to the Reporting Person continuing to be a service provider on each such vesting date.

F2 · derivative.expiration_date: The RSUs were approved by the Compensation Committee of the Issuer's Board of Directors in connection with certain consulting services being provided by the Reporting Person. 25% of the RSUs will vest on each of January 1, 2023, April 1, 2023, July 1, 2023 and October 1, 2023, subject in each case to the Reporting Person continuing to be a service provider on each such vesting date.

SEC source: 0001209191-22-052732 · doc4.xml · derivative · entry 5

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,719

Underlying: Common Stock · 3,906 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Impinj common stock.

F4 · derivative.exercise_date: On September 5, 2019, the reporting person was granted 62,500 restricted stock units ("RSUs"), one fourth of which vested on July 1, 2020, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 1, 2022.

F4 · derivative.expiration_date: On September 5, 2019, the reporting person was granted 62,500 restricted stock units ("RSUs"), one fourth of which vested on July 1, 2020, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on October 1, 2022.

SEC source: 0001209191-22-052732 · doc4.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 303,852

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-050652 · doc4.xml · nonDerivative · entry 4

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,734

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $88.17 to $88.54, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001209191-22-050652 · doc4.xml · nonDerivative · entry 3

MECKLAI HUSSEIN · CIK 0001908089 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,914

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $87.1401 to $88.14, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.