PI

SEC source: 0001415889-24-020636 · form4-08022024_080809.xml · nonDerivative · entry 4

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,949

F1 · kind: The sales reported by Mr. Dossett were effected pursuant to a 10b5-1 trading plan effective May 1, 2024.

F4 · price: This transaction was executed in multiple trades at prices ranging from $157.85 to $158.835. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-020636 · form4-08022024_080809.xml · nonDerivative · entry 3

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,359

F1 · kind: The sales reported by Mr. Dossett were effected pursuant to a 10b5-1 trading plan effective May 1, 2024.

F3 · price: This transaction was executed in multiple trades at prices ranging from $156.77 to $157.565. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-020636 · form4-08022024_080809.xml · nonDerivative · entry 2

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 72,797

F1 · kind: The sales reported by Mr. Dossett were effected pursuant to a 10b5-1 trading plan effective May 1, 2024.

F2 · price: This transaction was executed in multiple trades at prices ranging from $155.76 to $156.72. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-020636 · form4-08022024_080809.xml · nonDerivative · entry 1

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 78,642

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-019602 · form4-07162024_090740.xml · nonDerivative · entry 4

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,104

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

SEC source: 0001415889-24-019602 · form4-07162024_090740.xml · nonDerivative · entry 3

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,144

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $175.60 to $176.36, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019602 · form4-07162024_090740.xml · nonDerivative · entry 2

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,250

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $174.55 to $175.41, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019601 · form4-07162024_090726.xml · nonDerivative · entry 4

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,642

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

SEC source: 0001415889-24-019601 · form4-07162024_090726.xml · nonDerivative · entry 3

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,682

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $175.57 to $176.24, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019601 · form4-07162024_090726.xml · nonDerivative · entry 2

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,797

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $174.55 to $175.49, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019597 · form4-07162024_090704.xml · nonDerivative · entry 4

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 291,412

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

SEC source: 0001415889-24-019597 · form4-07162024_090704.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 291,508

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $175.59 to $176.36, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019597 · form4-07162024_090704.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 291,804

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $174.555 to $175.42, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019599 · form4-07162024_090743.xml · nonDerivative · entry 4

Baker Cary · CIK 0001705407 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,760

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $176.64 to $176.68, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019599 · form4-07162024_090743.xml · nonDerivative · entry 3

Baker Cary · CIK 0001705407 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,802

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $175.575 to $176.31, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019599 · form4-07162024_090743.xml · nonDerivative · entry 2

Baker Cary · CIK 0001705407 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,924

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $174.555 to $175.41, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019602 · form4-07162024_090740.xml · derivative · entry 5

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,282

Underlying: Common Stock · 1,093 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 17,500 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 17,500 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

SEC source: 0001415889-24-019602 · form4-07162024_090740.xml · nonDerivative · entry 1

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,520

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-019601 · form4-07162024_090726.xml · derivative · entry 5

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,750

Underlying: Common Stock · 1,250 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 20,000 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 20,000 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

SEC source: 0001415889-24-019601 · form4-07162024_090726.xml · nonDerivative · entry 1

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,117

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-019597 · form4-07162024_090704.xml · derivative · entry 6

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,375

Underlying: Common Stock · 3,125 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of Impinj common stock.

F5 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 50,000 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

F5 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 50,000 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

SEC source: 0001415889-24-019597 · form4-07162024_090704.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 292,599

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-019599 · form4-07162024_090743.xml · derivative · entry 5

Baker Cary · CIK 0001705407 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,813

Underlying: Common Stock · 937 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of Impinj common stock.

F6 · derivative.exercise_date: On April 12, 2021, the reporting person was granted 15,000 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

F6 · derivative.expiration_date: On April 12, 2021, the reporting person was granted 15,000 RSUs, one fourth of which vested on April 12, 2022, with an additional one-sixteenth of such RSUs vesting every three months thereafter. One-sixteenth of these RSUs vested on July 12, 2024.

SEC source: 0001415889-24-019599 · form4-07162024_090743.xml · nonDerivative · entry 1

Baker Cary · CIK 0001705407 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,116

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-019445 · form4-07092024_110755.xml · derivative · entry 6

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,536

Underlying: Common Stock · 5,000 shares

Expires 2028-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option became fully vested on June 11, 2022.

SEC source: 0001415889-24-019445 · form4-07092024_110755.xml · nonDerivative · entry 4

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,474

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $163.115 to $163.1825, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019445 · form4-07092024_110755.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,996

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $162.10 to $163.08, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019445 · form4-07092024_110755.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 292,977

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $161.0901 to $162.02, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-019445 · form4-07092024_110755.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 294,474

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · derivative · entry 14

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,536

Underlying: Common Stock · 5,000 shares

Expires 2028-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option became fully vested on June 11, 2022.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 11

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,474

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 10

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,824

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F9 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $155.25 to $156.245, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 9

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 293,391

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F8 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $154.25 to $155.22, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 8

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 294,474

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · derivative · entry 13

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 85,536

Underlying: Common Stock · 5,000 shares

Expires 2028-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option became fully vested on June 11, 2022.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 7

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,474

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $156.32 to $156.6775, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 6

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 290,306

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F6 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $155.265 to $156.025, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 5

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 291,399

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F5 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $154.09 to $154.99, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 4

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 291,808

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F4 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $153.045 to $153.905, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 3

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 293,193

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $151.975 to $152.855, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 2

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 293,585

F1 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $150.84 to $151.83, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018977 · form4-07022024_090747.xml · nonDerivative · entry 1

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 294,474

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-018171 · form4-06252024_110654.xml · derivative · entry 14

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 90,536

Underlying: Common Stock · 5,000 shares

Expires 2028-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: The option became fully vested on June 11, 2022.

SEC source: 0001415889-24-018171 · form4-06252024_110654.xml · nonDerivative · entry 9

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,474

F4 · kind: The sales reported by Dr. Diorio were effected pursuant to a Rule 10b5-1 trading plan effective on February 28, 2024.

F7 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $150.00 to $150.155, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018171 · form4-06252024_110654.xml · nonDerivative · entry 8

DIORIO CHRIS PH.D. · CIK 0001677721 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 294,474

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-24-018175 · form4-06252024_110647.xml · nonDerivative · entry 3

PHELAN CATHAL G · CIK 0001259761 · Director · CHIEF INNOVATION OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,669

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $148.04 to $148.59, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018175 · form4-06252024_110647.xml · nonDerivative · entry 2

PHELAN CATHAL G · CIK 0001259761 · Director · CHIEF INNOVATION OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,725

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units.

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $146.945 to $147.92 inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018174 · form4-06252024_110616.xml · nonDerivative · entry 4

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,427

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $147.95 to $148.62, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018174 · form4-06252024_110616.xml · nonDerivative · entry 3

MECKLAI HUSSEIN · CIK 0001908089 · CHIEF OPERATING OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,730

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F2 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $146.7401 to $147.68, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

SEC source: 0001415889-24-018173 · form4-06252024_110647.xml · nonDerivative · entry 4

DOSSETT JEFFREY · CIK 0001578147 · CHIEF REVENUE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 62,867

F1 · kind: These shares were disposed of in non-discretionary transactions to cover the reporting person's tax withholding obligations in connection with the settlement of an award of restricted stock units ("RSUs").

F3 · price: The "Amount" and "Price" reported in this Column 4 reflect the aggregate number and weighted-average price, respectively, of shares sold. These shares were sold in multiple transactions at prices ranging from $147.98 to $148.83, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.