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Nasdaq · USD

ORKA

Oruka Therapeutics, Inc.

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3781
SEC CIK
0000907654
Parsed reports
188

Last 12 months

Inside the activity.

0 purchase rows · 112 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202504
Jan 202605
Feb 202602
Mar 2026010
Apr 202603
May 2026016
Jun 2026015
Jul 2026012
Aug 2026015
Sep 2026023
Oct 202607

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 15, 2026 Filed May 16, 2026 00:17 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 100 $63.52 $6,352.00
Disclosure

SEC source: 0000907654-26-000039 · form4.xml · nonDerivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,377

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

Read SEC document
May 15, 2026 Filed May 16, 2026 00:17 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 2,100 $62.42 $131,088.30
Disclosure

SEC source: 0000907654-26-000039 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,477

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $62.02 to $62.89, inclusive.

Read SEC document
May 15, 2026 Filed May 16, 2026 00:17 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 4,800 $61.56 $295,494.72
Disclosure

SEC source: 0000907654-26-000039 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,577

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.93 to $61.90, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Read SEC document
May 15, 2026 Filed May 16, 2026 00:17 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000039 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 40,377

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 15, 2026 Filed May 16, 2026 00:17 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000039 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,877

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
Exercise / conversionEmployee Warrant (right to buy) · Derivative 5,000 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · derivative · entry 8

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,996

Underlying: Common Stock · 5,000 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 3, 2025 and as to 1/48 of the underlying shares monthly from April 3, 2025.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 100 $68.48 $6,848.00
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 7

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 236,984

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 200 $67.16 $13,431.00
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 6

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 237,084

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.11 to $67.20, inclusive.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 400 $66.06 $26,422.00
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 5

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 237,284

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.85 to $66.23, inclusive.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 300 $65.10 $19,530.00
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 4

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 237,684

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $64.85 to $65.28, inclusive.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 1,800 $64.15 $115,467.84
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 3

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 237,984

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.59 to $64.55, inclusive.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 2,200 $62.58 $137,685.46
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 2

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 239,784

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $62.33 to $62.83, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5) and (6) to this Form 4.

Read SEC document
May 01, 2026 Filed May 1, 2026 22:25 UTC
Sandler Laura LeeChief Operating Officer
Exercise / conversionCommon Stock 5,000 $7.80 $39,000.00
Disclosure

SEC source: 0000907654-26-000037 · form4.xml · nonDerivative · entry 1

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 241,984

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionEmployee Warrant (right to buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · derivative · entry 7

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 182,492

Underlying: Common Stock · 3,500 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · derivative · entry 6

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 211,063

Underlying: Common Stock · 3,500 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 500 $67.38 $33,692.00
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · nonDerivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,377

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.35 to $67.41, inclusive.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 2,273 $66.56 $151,300.65
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,877

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.31 to $67.15, inclusive.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 4,227 $65.73 $277,836.91
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,150

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.31 to $66.29, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3) and (4) to this Form 4.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 40,377

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:45 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000035 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,877

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:09 UTC
Agarwal ArjunSenior Vice President, Finance
SaleCommon Stock 395 $41.30 $16,313.50
Disclosure

SEC source: 0000907654-26-000032 · form4.xml · nonDerivative · entry 1

Agarwal Arjun · CIK 0002033974 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,863

F1 · kind: The reported sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:10 UTC
Klein Lawrence OttoDirector · Chief Executive Officer
SaleCommon Stock 1,729 $41.30 $71,407.70
Disclosure

SEC source: 0000907654-26-000033 · form4.xml · nonDerivative · entry 1

Klein Lawrence Otto · CIK 0001762583 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 927,309

F1 · kind: The reported sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:08 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 600 $41.30 $24,780.00
Disclosure

SEC source: 0000907654-26-000031 · form4.xml · nonDerivative · entry 1

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 236,984

F1 · kind: The reported sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionEmployee Warrant (right to buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · derivative · entry 8

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 185,992

Underlying: Common Stock · 3,500 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · derivative · entry 7

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 214,563

Underlying: Common Stock · 3,500 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 641 $41.30 $26,473.30
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 6

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,377

F5 · kind: These sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 1,177 $41.94 $49,358.79
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,018

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.75 to $42.28, inclusive.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 2,902 $41.20 $119,568.78
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,195

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.72 to $41.70, inclusive.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 2,921 $40.11 $117,158.68
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 38,097

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.65 to $40.64, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3) and (4) to this Form 4.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:04 UTC
Quinlan Paul TGeneral Counsel
SaleCommon Stock 733 $41.30 $30,272.90
Disclosure

SEC source: 0000907654-26-000029 · form4.xml · nonDerivative · entry 1

Quinlan Paul T · CIK 0001333277 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,767

F1 · kind: The reported sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 23:47 UTC
Sandler Laura LeeChief Operating Officer
Exercise / conversionEmployee Warrant (right to buy) · Derivative 5,000 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000022 · form4.xml · derivative · entry 4

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 89,996

Underlying: Common Stock · 5,000 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 3, 2025 and as to 1/48 of the underlying shares monthly from April 3, 2025.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 23:47 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 2,675 $33.81 $90,435.60
Disclosure

SEC source: 0000907654-26-000022 · form4.xml · nonDerivative · entry 3

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 237,584

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $33.66 to $34.33, inclusive.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 23:47 UTC
Sandler Laura LeeChief Operating Officer
SaleCommon Stock 2,325 $33.28 $77,386.00
Disclosure

SEC source: 0000907654-26-000022 · form4.xml · nonDerivative · entry 2

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 240,259

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.66 to $33.64, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 23:47 UTC
Sandler Laura LeeChief Operating Officer
Exercise / conversionCommon Stock 5,000 $7.80 $39,000.00
Disclosure

SEC source: 0000907654-26-000022 · form4.xml · nonDerivative · entry 1

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 242,584

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionEmployee Warrant (right to buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · derivative · entry 6

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 189,492

Underlying: Common Stock · 3,500 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · derivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 218,063

Underlying: Common Stock · 3,500 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

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February 17, 2026 Filed Feb 17, 2026 22:24 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 936 $32.78 $30,686.01
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,018

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.69 to $32.93, inclusive.

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February 17, 2026 Filed Feb 17, 2026 22:24 UTC
Goncalves JoanaChief Medical Officer
SaleCommon Stock 6,064 $32.30 $195,872.66
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,954

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.68 to $32.67, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

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February 17, 2026 Filed Feb 17, 2026 22:24 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC
Goncalves JoanaChief Medical Officer
Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC
Goncalves JoanaChief Medical Officer
GrantEmployee Stock Option (right to buy) · Derivative 130,000 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0000907654-26-000018 · form4.xml · derivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,000

Underlying: Common Stock · 130,000 shares

Expires 2036-01-22

F2 · derivative.exercise_date: The option vests as to 1/48 of the underlying shares monthly from January 1, 2026.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC
Goncalves JoanaChief Medical Officer
GrantCommon Stock 32,500 $0.00 $0.00
Disclosure

SEC source: 0000907654-26-000018 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,018

F1 · shares: The grant vests as to 1/16 of the shares on each March 14, June 14, September 14 and December 14 (or if not a trading day, the immediately preceding trading day).

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC
Agarwal ArjunSVP, Finance
GrantEmployee Stock Option (right to buy) · Derivative 70,000 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0000907654-26-000016 · form4.xml · derivative · entry 2

Agarwal Arjun · CIK 0002033974 · SVP, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option vests as to 1/48 of the underlying shares monthly from January 1, 2026.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC
Agarwal ArjunSVP, Finance
GrantCommon Stock 17,500 $0.00 $0.00
Disclosure

SEC source: 0000907654-26-000016 · form4.xml · nonDerivative · entry 1

Agarwal Arjun · CIK 0002033974 · SVP, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,258

F1 · shares: The grant vests as to 1/16 of the shares on each March 14, June 14, September 14 and December 14 (or if not a trading day, the immediately preceding trading day).

F2 · balance_after: Includes 1,758 shares acquired under the Oruka stock purchase plan on December 8, 2025.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC
Sandler Laura LeeChief Operating Officer
GrantEmployee Stock Option (right to buy) · Derivative 130,000 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0000907654-26-000017 · form4.xml · derivative · entry 2

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,000

Underlying: Common Stock · 130,000 shares

Expires 2036-01-22

F2 · derivative.exercise_date: The option vests as to 1/48 of the underlying shares monthly from January 1, 2026.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC
Sandler Laura LeeChief Operating Officer
GrantCommon Stock 32,500 $0.00 $0.00
Disclosure

SEC source: 0000907654-26-000017 · form4.xml · nonDerivative · entry 1

Sandler Laura Lee · CIK 0002075401 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 237,584

F1 · shares: The grant vests as to 1/16 of the shares on each March 14, June 14, September 14 and December 14 (or if not a trading day, the immediately preceding trading day).

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:38 UTC
Klein Lawrence OttoDirector · Chief Executive Officer
GrantEmployee Stock Option (right to buy) · Derivative 306,700 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0000907654-26-000015 · form4.xml · derivative · entry 2

Klein Lawrence Otto · CIK 0001762583 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 306,700

Underlying: Common Stock · 306,700 shares

Expires 2036-01-22

F2 · derivative.exercise_date: The option vests as to 1/48 of the underlying shares monthly from January 1, 2026.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:38 UTC
Klein Lawrence OttoDirector · Chief Executive Officer
GrantCommon Stock 76,700 $0.00 $0.00
Disclosure

SEC source: 0000907654-26-000015 · form4.xml · nonDerivative · entry 1

Klein Lawrence Otto · CIK 0001762583 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 929,038

F1 · shares: The grant vests as to 1/16 of the shares on each March 14, June 14, September 14 and December 14 (or if not a trading day, the immediately preceding trading day).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.